CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1989), master's at Periodontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1995) and doctorate at Periodontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1998). Has experience in Odontology, focusing on Periodontology, acting on the following subjects: periodontia, doença periodontal, enxertos, periodontal regeneration and biomaterials. (Source: Lattes Curriculum)
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In the area of biomedical research, microcomputed tomography has been an essential tool for investigating the structure and composition of mineralized tissues, such as bones and teeth, also allowing the evaluation of soft tissues, such as the cardiovascular and respiratory systems. High-resolution images and three-dimensional reconstruction make it possible to map samples ex vivo or in vi…
Intraoral bone defects comprise clinical conditions caused by different factors, which are pathological, traumatic and iatrogenic. The search for regenerative methods and biomaterials that promote the resolution of bone defects and the restoration of oral functional and aesthetic conditions are fundamental for the maintenance of the health and well-being of the population. The present stu…
Over the past decades obesity has been increasing worldwide and represents a major risk factor for many chronic diseases. Meta-analyses have demonstrated that obesity is also associated with periodontitis, a bacteria-induced inflammatory disease of the tooth-supporting tissues. Obesity is characterized by excess adipose tissue, which secrets bioactive molecules called adipokines. Although…
With a high success ratio observed by the use of implants (97%), the development of new alloys and surface treatments has been the main objective in the Implantology research area. Periodontal tissue responses towards these modifications are determinant for implant integration with the human body. The proposition of this study is characterize a new titanium-molybdenum alloy with different…
Several studies have been conducted to understand distinctly the effects of periodontal diseases and of orthodontic movements on the periodontal tissues. But the effects of both processes presented together have not been fully elucidated. The aim of these in vitro and in vivo studies is to investigate the interactions of microbial and biomechanical signals on models that mimic the influe…
(Only some records are available in English at this moment)
The endocannabinoid system (EC) of cell signaling regulates bone homeostasis, and activation of its CB2 receptor has been associated with the inhibition of bone resorption and increased bone formation, making it a potential therapeutic target for osteoporosis and other osteometabolic diseases. These sistemic diseases affect the orthodontic tooth movement (OTM). Thus, the aim of the prese…
Bioglasses (BV) are widely and successfully used for bone regeneration in orthopedic, dental and maxillofacial applications. In parallel, hydrogels containing bone marrow mesenchymal stem cells (BMSCs) have also been proposed for bone regeneration within the contemporary proposal of multipotent cell transplantation in tissue engineering. However, the insufficient osteoinduction capacity o…
Pure titanium (Ti) and its alloys are the most used materials for dental implants due to their excellent corrosion resistance and superior mechanical properties. However, their biological inertness can lead to clinical failures. In parallel, in regenerative medicine, bioactive glasses (BGs) are considered outstanding biomaterials in the field of tissue restoration due to their remarkable …
(Only some records are available in English at this moment)
Intraoral bone defects comprise clinical conditions caused by different factors, including periodontitis and peri-implantitis. These are chronic inflammatory diseases associated with dysbiosis of the oral microbiota, which affect periodontal and peri-implant tissues, resulting in progressive loss of supporting bone. The use of natural products for the treatment of intraoral pathological c…
The clinical failure of dental implants can occur due to inadequate osseointegration. Poor osseointegration induces mobility, inflammation, and bone resorption, leading to treatment failure. Due to systemic challenges related to insufficiency and/or poor quality of peri-implant bone tissue, which can compromise osseointegration, the development of titanium surfaces with an osteogenic and …
Osteoporosis is an osteometabolic disease, characterized by a reduction in bone mass in long bones and vertebrae, which occurs due to a decrease in estrogen levels, especially in postmenopausal women. Recently, a new drug based on an anti-sclerostin antibody (Scl-Ab) was approved for postmenopausal osteoporosis treatment. Its mechanism of action corresponds to an increase in the activity …
(Only some records are available in English at this moment)
Monocytic myeloid-derived suppressor cells (M-MDSCs) play a crucial role in the immunopathology of periodontitis, contributing to inflammatory bone loss through immune suppression and osteoclast-mediated resorption. Similarly, the cannabinoid receptor type 2 (CB2) activation has been shown to modulate immune responses and bone remodeling, suggesting a potential role in periodontitis. Howe…
Mucogingival surgeries are widely used in Periodontology and Implantology to improve aesthetics and gingival health. Soft tissue grafting has emerged as an effective technique for these purposes, helping to restore gingival contour and thickness, especially around dental implants and in areas of gingival recession. Minimally invasive graft techniques have attracted attention due to their …
Dental implants with osteogenic potential loaded with Calcium (Ca) and Strontium (Sr) may be promising to modulate bone turnover towards osteogenesis and accelerate osseointegration. In this sense, the candidate's master's project, supported by FAPESP - process 2022/08006-7, is dedicated to evaluate the effect of the addition of Ca, Sr and osteogenic biomolecules - dexamethasone, ascorbic…
Surface treatments, development of new alloys and functionalization of implant surfaces with bioactive elements have been the objective of recent studies in the area of implant dentistry aiming to contribute to the process of osseointegration. The functionalization of the titanium surface with strontium can be performed by different methods. The purpose of this study is to compare, in vit…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 10 / 7 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 28 / 24 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 7 / 7 | Completed scholarships abroad |
| 54 / 47 | All research grants and scholarships |
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