CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bsc in Biology from Universidade Federal do Rio de Janeiro, Ms in Molecular Biology from Universidade Federal do Rio de Janeiro and PhD in Biochemistry from Universidade de São Paulo. Research experience focused on Molecular Microbiology, specially on the following subjects: bacterial secretion systems, regulation of gene expression in bacteria, bacterial toxins, microbial interactions. (Source: Lattes Curriculum)
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Bacterial secretion systems are protein nanomachines that specifically translocate protein substrates (effectors) to target cells or to the extracellular milieu, playing major roles in biotic and abiotic interactions. Type VI secretion systems (T6SSs) are widespread in Proteobacteria and have been mainly characterized for their roles as antibacterial weapons in interspecies competition. S…
The CEPID B3 is a network with research hubs based in São Paulo (IQ-USP, ICB-USP), Campinas (IB-UNICAMP, IAC), Ribeirão Preto (FCFRP-USP, FMRP-USP) and Rio Claro (UNESP) that will collaborate to carry out cutting edge basic research into molecular mechanisms that are of prime importance to understand bacterial reproduction, multicellular behavior, competition, colonization and interaction…
Bacterial secretion systems are transenvelope protein complexes that promote the translocation of effector proteins directly into target cells or the extracellular milieu, and thus play fundamental roles in environmental adaptation. Type VI secretion systems (T6SS) are widespread in Proteobacteria and target prokaryotic and/or eukaryotic cells, acting as antibacterial weapons or anti-host…
Bacterial type VI secretion systems (T6SS) are multiprotein complexes that translocate protein effectors and/or toxins to target cells, playing major roles in interspecies competition, virulence and environmental adaptation in several bacteria. Xanthomonas citri subsp. citri is the causative agent of citrus canker disease, infecting all citrus crops. Previous studies by our research group…
Bacterial type VI secretion systems (T6SS) are protein complexes that span the bacterial cell envelope and are involved in protein translocation to target cells. It was not until recently that T6SS were first described and structural and functional studies indicate that they act by a mechanism similar to injection of DNA into bacterial cells by bacteriophages, specially the T4 phage. T6SS…
Xanthomonas citri pv citri (Xcc) is the bacterium that causes citrus canker, a disease that affects several plant species of the Citrus genus and causes losses for producers. In the process of plant infection, various conditions are encountered by pathogens and mechanisms have been selected to deal with adversity. Of relevance in this process are the different types of secretion systems, …
Acinetobacter baumannii is a Gram-negative bacterium considered an emerging opportunistic pathogen of major concern in hospital settings, due to its extensive resistance to antibiotics and ability to cause severe infections, primarily affecting immunocompromised patients undergoing invasive procedures, catheter use, and antibiotic therapy. Furthermore, A. baumannii is characterized by a g…
Bacterial sigma factors are subunits of the RNA polymerase that confer specificity to promoter DNA sequences and trigger transcription initiation. The vegetative sigma factor is responsible for transcription of housekeeping genes, whereas alternative sigma factors recognize different promoter sequences and regulate specific subsets of genes in response to variations in environmental condi…
(Only some records are available in English at this moment)
Bacteria are ubiquitous organisms that have a vast repertoire of strategies to survive and respond to environmentalchanges. The Proteobacteria Xanthomonas citri subsp. citri is the causative agent of citrus canker, a disease that resultsfrom colonization of Citrus plant tissue and affects all economically important cultivars. Secretion Systems are proteincomplexes that cross the bacterial…
Citriculture, an important economic activity in Brazil, is threatened by diseases that attack crops, such as citrus canker produced by Xanthomonas citri, which leads to reduced productivity and significant economic losses. Bacterial sigma factors are dissociable subunits of RNA polymerases that are responsible for the recognition of promoters and for promoting the initiation of transcript…
(Only some records are available in English at this moment)
The phytopathogenic bacterium Xanthomonas citri pv. citri is the causative agent of citrus canker disease, which causes premature abscission of plant organs like branches and fruits and severely impacts the productivity of a wide range of citrus cultivars. Secretion systems are bacterial envelope protein complexes that translocate effector proteins to target cells or the external environm…
Type 6 Secretion Systems (T6SS) are bacterial nanomachines that deliver effector proteins or toxins directly into prokaryotic and/or eukaryotic target cells. These devices are involved in the interspecific competition and virulence playing fundamental roles in bacterial fitness in their ecological niches. The T6SS of Xanthomonas citri pv citri is required for resistance against the bacter…
| 3 / 3 | Ongoing grants |
| 4 / 2 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 10 / 8 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 25 / 21 | All research grants and scholarships |
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