CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Bacharelado Em Química from Universidade Estadual Paulista Júlio de Mesquita Filho (1996), master's at Chemistry from Universidade Estadual Paulista Júlio de Mesquita Filho (1999) and doctorate at Chemistry from Universidade Estadual Paulista Júlio de Mesquita Filho (2003). Has experience in Chemistry, acting on the following subjects: complexos pirazólicos de paládio, pseudo-haletos, paládio(ii), polímeros de coordenação and auto-organização molecular. (Source: Lattes Curriculum)
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The development of drug resistance remains the main limiting factor for the effectiveness of the treatment of cancer patients. The challenge to overcome resistance is multifaceted and highly complex. The search for new molecules to compose new combination chemotherapy regimens is a very active research area for cancer treatment. Particularly, metal complexes naturally emerge as very inter…
This project deals with the synthesis, characterization and evaluation of the antitumor potential of compounds [PdCl(C2,N-ox)(PR3)], [Pd2Cl2(C2,N-ox)2(µ-PP)] and [PdCl(CINTSC)(PR3)] (PR3 = tertiary monodentate phosphanes, PP = diphosphanes; ox = orthometallated oximes functionalized or not, CINTSC = thiosemicabazones derived from cinmaldehyde). The compounds will be characterized by eleme…
(Only some records are available in English at this moment)
Breast cancer is one of the main types of malignant tumors that affect women. The percentage of new cases of female breast cancer predicted for Brazil between 2023 and 2025 (10.5%), represents around 74 thousand cases, that is, a risk of 66.54 new cases for every 100 thousand women. Carboplatin is indicated in combination therapy with other chemotherapy drugs or anti-HER2 agents for the t…
Chagas disease has the protozoan Trypanosoma cruzi as its etiological agent and is a neglected tropical disease endemic to Latin American countries. It is estimated that 6 to 8 million people in these countries suffer from the disease and that more than 75 million are at risk of contracting it. The drugs currently in use have low specificity, which results in several side effects. Further…
Cancer is the second disease that causes the most deaths in the world. According to the NationalCancer Institute (INCA), 704.000 new cases of cancer are expected in Brazil for each year of the2023-2025 triennium. Given the complexity of this set of diseases, the discovery of new moleculescapable of destroying tumor cells without being toxic to the patient represents an importantchallenge.…
Breast Cancer (BC) is the most common type of non-cutaneous cancer and the second leading cause of cancer death among women worldwide. Breast tumors are characterized by differences in behavior, biological evolution and therapeutic responses. Due to its heterogeneity and complexity, the discovery of new molecules to increase our available arsenal in the war against CM is an urgent and cha…
(Only some records are available in English at this moment)
This work deals with the synthesis, characterization and human telomeric G-quadruplex DNA binding studies on new chelates of general formulae [M(bisq)(N-X)]+n (M = Pd(II), Pt(II); bisq = 3,32-biisoquinoline; N-X (X = C) = C2,N-benzylidenemethylamine, C2,N-benzaldehydeoxime type-ligands; N-X (X = S) = thiosemicarbazide type ligands; n = 1,2). These complexes exhibit pre-conceived structura…
| 4 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 10 / 6 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 16 / 12 | All research grants and scholarships |
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