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Marcos Roberto de Mattos Fontes

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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Graduation in Physics at the University of São Paulo (1989), Master in Sciences (1992), and PhD (1995) in Physics by University of São Paulo; Post-doctorals at the University of Melbourne (2001) and University of Queensland (2004), both in Australia. At this moment, he is a Full Professor in Biophysics at the São Paulo State University (UNESP) - Institute of Biosciences - Botucatu/SP. He is the head of the Department of Physics and Biophysics and head of the Structural Biology Laboratory. He was the coordinator of Applied and General Biology graduation course (4 years) and head of the Department of Physics and Biophysics by three terms. He has experience in Molecular Biophysics field, including protein crystallography, bioinformatics, calorimetry and other biophysical techniques. The main research fields include animal toxins, nuclear import proteins, DNA repair proteins and other proteins with biotechnological importance. He was responsible for the third laboratory in South America able to work with protein crystallography techniques and he worked in the project responsible for the first protein solved by crystallography in South America (1995) during his PhD. He has supervised 25 MSc/PhD and over than 30 diploma thesis and already coordinated over than 20 research projects granted by FAPESP, CNPq e FINEP (Brazilian governmental research agencies). He is the reviewer of over 20 scientific journals and was responsible for oral communications in several international conferences. He is the elected vice-president of Brazilian Society of Toxinology. He already published 110 scientific articles in important scientific journals which were already cited more than 2600 times in other articles with H index of 28. (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (11)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications8
Citations8
Cit./Article1.0
Data from Web of Science

TOYAMA, DANIELA DE OLIVEIRA; GAETA, HENRIQUE HESSEL; TERASHIMA DE PINHO, MARCUS VINICIUS; PENA FERREIRA, MARCELO JOSE; ROMOFF, PAULETE; MATIOLI, FABIO FILIPPI; MAGRO, ANGELO JOSE; DE MATTOS FONTES, MARCOS ROBERTO; TOYAMA, MARCOS HIKARI. An Evaluation of 3-Rhamnosylquercetin, a Glycosylated Form of Quercetin, against the Myotoxic and Edematogenic Effects of sPLA(2) from Crotalus durissus terrificus. BIOMED RESEARCH INTERNATIONAL, . Web of Science Citations: 1. (13/12077-8, 11/06704-4, 12/06502-5)

CHIOATO‚ L.; WARD‚ R.J.. Mapping structural determinants of biological activities in snake venom phospholipases A2 by sequence analysis and site directed mutagenesis. Toxicon, v. 42, n. 8, p. 869-883, .

WATANABE‚ L.; SHANNON‚ J.D.; VALENTE‚ R.H.; RUCAVADO‚ A.; ALAPE-GIRÓN‚ A.; KAMIGUTI‚ A.S.; THEAKSTON‚ R.D.G.; FOX‚ J.W.; GUTIÉRREZ‚ J.M.; ARNI‚ R.K.. Amino acid sequence and crystal structure of BaP1‚ a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities. Protein Science, v. 12, n. 10, p. 2273-2281, .

SOARES‚ A.M.; FONTES‚ M.R.M.; GIGLIO‚ J.R.. Phospholipase A2 myotoxins from Bothrops snake venoms: structure-function relationship. CURRENT ORGANIC CHEMISTRY, v. 8, n. 17, p. 1677-1690, .

VIRGILIO, STELA; CUPERTINO, FERNANDA BARBOSA; BERNARDES, NATALIA ELISA; FREITAS, FERNANDA ZANOLLI; SEKIJIMA TAKEDA, AGNES ALESSANDRA; DE MATTOS FONTES, MARCOS ROBERTO; BERTOLINI, MARIA CELIA. Molecular Components of the Neurospora crassa pH Signaling Pathway and Their Regulation by pH and the PAC-3 Transcription Factor. PLoS One, v. 11, n. 8, . Web of Science Citations: 2. (12/09435-7, 13/24705-3)

PAVANI, RAPHAEL SOUZA; DA SILVA, MARCELO SANTOS; HENRIQUE FERNANDES, CARLOS ALEXANDRE; MORINI, FLAVIA SOUZA; ARAUJO, CHRISTIANE BEZERRA; DE MATTOS FONTES, MARCOS ROBERTO; SANT'ANNA, OSVALDO AUGUSTO; MACHADO, CARLOS RENATO; CANO, MARIA ISABEL; FRAGOSO, STENIO PERDIGAO; et al. Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. PLoS Neglected Tropical Diseases, v. 10, n. 12, . Web of Science Citations: 1. (15/10580-0, 13/17864-8, 14/24170-5, 14/02978-0, 13/07467-1)

BORGES, RAFAEL J.; CARDOSO, FABIO F.; FERNANDES, CARLOS A. H.; DREYER, THIAGO R.; DE MORAES, DELKIA S.; FLORIANO, RAFAEL S.; RODRIGUES-SIMIONI, LEA; FONTES, MARCOS R. M.. Functional and structural studies of a Phospholipase A(2)-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, v. 1861, n. 1, A, p. 3199-3209, . Web of Science Citations: 1. (13/00873-4, 15/17286-0)

MAKIYAMA, RODRIGO K.; FERNANDES, CARLOS A. H.; DREYER, THIAGO R.; MODA, BRUNO S.; MATIOLI, FABIO F.; FONTES, MARCOS R. M.; MAIA, IVAN G.. Structural and thermodynamic studies of the tobacco calmodulin-like rgs-CaM protein. International Journal of Biological Macromolecules, v. 92, p. 1288-1297, . Web of Science Citations: 2. (13/17864-8, 10/03001-0)

FERNANDES, CARLOS A. H.; PAZIN, WALLANCE M.; DREYER, THIAGO R.; BICEV, RENATA N.; CAVALCANTE, WALTER L. G.; FORTES-DIAS, CONSUELO L.; ITO, AMANDO S.; OLIVEIRA, CRISTIANO L. P.; FERNANDEZ, ROBERTO MORATO; FONTES, MARCOS R. M.. Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism. SCIENTIFIC REPORTS, v. 7, . Web of Science Citations: 1. (15/17286-0, 13/17864-8)

SALVADOR, GUILHERME H. M.; DOS SANTOS, JULIANA I.; LOMONTE, BRUNO; FONTES, MARCOS R. M.. Crystal structure of a phospholipase A(2) from Bothrops asper venom: Insights into a new putative ``myotoxic cluster{''}. Biochimie, v. 133, p. 95-102, . Web of Science Citations: 0. (15/24167-7, 15/17286-0)

CAVALCANTE, WALTER L. G.; NORONHA-MATOS, JOSE B.; TIMOTEO, MARIA A.; FONTES, MARCOS R. M.; GALLACCI, MARCIA; CORREIA-DE-SA, PAULO. Neuromuscular paralysis by the basic phospholipase A(2) subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage. Toxicology and Applied Pharmacology, v. 334, p. 8-17, . Web of Science Citations: 0. (13/03624-5, 13/17864-8, 12/00428-8)

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