CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associate Professor in the Department of Genetics, Microbiology and Immunology at the Institute of Biosciences, São Paulo State University (UNESP), Botucatu campus, and Coordinator of the Graduate Program in Biological Sciences (Genetics). He is the leader of the research group The Non-Coding Genome (UNESP), a collaborator of the Structure and Evolution of Genomes group (UNESP), and a member of the Pescado para Saúde Network (NPOP/CCD-FAPESP). He is actively involved in national and international scientific cooperation, developing studies in vertebrate genomics, with a focus on freshwater and marine fishes, encompassing microRNAs and other non-coding genome elements, with applications in conservation, fisheries, and aquaculture. He serves as a member of editorial boards of scientific journals, acts as an ad hoc reviewer for international journals, and as a reviewer for research proposals submitted to FAPESP and CNPq. He is also a member of the Brazilian Society for Evolutionary Biology (SBBE). (Source: Lattes Curriculum)
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Amidst global climate changes, understanding the genetic mechanisms of cold tolerance can bring significant gains to aquaculture. As ectothermic organisms, fish are sensitive to extreme temperature fluctuations due to the strong influence of the environment on their physiological functions. Currently, there are no commercially available genetic or epigenetic markers capable of selecting a…
The limited regenerative capacity of mammals has serious implications for tissue damage. Throughout the life cycle, loss of cells in long-lasting tissues such as brain, heart, skeletal muscles and thymus occurs due to the aging process itself and complications due to tissue damages such as amputation and cardiovascular diseases that can not be repaired by the patients tissue regeneration.…
MicroRNAs (miRNAs) are non-coding RNAs that regulate a wide range of biological pathways by post-transcriptionally modulating gene expression levels. Given that even a single miRNA may simultaneously control several biological functions, one would expect that they have the ability to properly sort among distinctive biological process in order to drive gene products production required by …
(Only some records are available in English at this moment)
Understanding the genetic mechanisms underlying tolerance to low temperatures is crucial for aquaculture, particularly in the context of global climate change. As ectothermic organisms, fish are highly sensitive to extreme temperature variations due to the strong influence of the environment on their physiological functions. Circulating extracellular microRNAs (c-miRNAs) remain largely un…
This research project aims to investigate the effects of editing the sp7 and runx2a genes on the epimorphic regeneration capacity of the caudal fin in zebrafish (Danio rerio), a valuable study model due to its unique ability to regenerate various types of tissues. Specific objectives include analyzing the expression profiles of edited genes (sp7 and runx2a) and regulatory microRNAs (miR-2…
In recent decades, coastal ecosystems have been affected by considerable environmental changes caused by human activities, leading to loss of biodiversity. To address this issue, species surveys of these transition areas between rivers and seas are a crucial tool for ecosystem preservation. However, conducting traditional surveys in marine and coastal environments can be expensive and cha…
Over the lifetime of organisms, cells in long-lasting tissues, such as the brain, heart, skeletal muscles and thymus, are inevitably lost due to the natural aging process and tissue damage, since the regenerative capacity is limited and variable between different organisms. In view of this, animal models have been used in translational research to look for possible solutions for tissue re…
(Only some records are available in English at this moment)
The Nile tilapia (Oreochromis niloticus) is an economically important farmed fish in different countries and particularly in Brazil. Crossbreding has been carried out between two strains of nile tilapia - Red color Stirling and wild type Chitralada strains. This crossing combines superior performance of Chitrlada strain with red dominant red coloration of Stirling strain. Although crossb…
The heart has undergone several morphological changes leading to an increased functional complexity during vertebrate evolution. Currently, such differences in morphological complexity are recognized as being a result of distinct expression profiles of protein-coding and regulatory non-coding RNAs (ncRNAs) genes. Among ncRNAs, microRNAs (miRNAs) have been described as key micromanagers in…