The agreement with CNPq - National Council for Scientific and Technological Development aims to implement the Program of Support for Excellence Centers - Pronex, in the State of São Paulo.
The agreement with CNPq - National Council for Scientific and Technological Development aims to implement the Program of Support for Excellence Centers - Pronex, in the State of São Paulo.
The present project aims the study of intermolecular interactions in transition metal complexes with organic ligands, with the objective of establishing the mechanism of action of these compounds as potential anticancer drugs, antituberculosis, antichagasic or antimalarial drugs. These studies consist of several steps that include the synthesis of the compounds, their spectroscopic charac…
Cancer is one of the most deadly diseases in the world, in addition to being always growing, both in number and in diversity. Thus, in view of the need for more efficient drugs than those found on the market, and with fewer side effects than those presented by the drugs used in the treatment of the disease, the development of organic or inorganic anticancer agents, in order to find new dr…
The development of metallic compounds to find new drug candidates for the treatment of cancer has gained increasing importance in the scientific field, considering that cancer is a serious public health problem worldwide. Therefore, several metallic compounds have been studied, seeking to identify more selective and effective compounds. In particular, ruthenium-based compounds have shown …
The development of metallic compounds, in order to find new drug candidates for the treatment of cancer, has gained increasing importance in the scientific field, given that this disease is a serious worldwide public health problem . For this, several transition metals have been used, seeking to identify more selective and effective compounds, without side effects. In particular, rutheniu…
(Only some records are available in English at this moment)
The development of metallic compounds to find new drug candidates for the treatment of cancer has gained increasing importance in the scientific field, considering that cancer is a serious public health problem worldwide. Therefore, several metallic compounds have been studied, seeking to identify more selective and effective compounds. In particular, ruthenium-based compounds have shown …
The present project aim the synthesis and characterizing ruthenium II semi-sandwich complexes containing binders of biological interest, as new candidates for metallopharmaceuticals, being an integral part of the thematic project "X-Ray Diffraction as a Tool in the Development of Potential Drugs" (2017 / 15850-0). In the synthesis stage, it is intended to perform a "screening" to evaluate…
Polysomnographic studies involving subjects with schizophrenia have reported the continuity of sleep disturbances, decreased slow-wave sleep, a reduction in the latency of REM sleep, increased the percentage of REM sleep and reducing the amount of NREM sleep in minutes. As for the polysomnographic findings in TB, the main feature seems to be the reduction of total sleep time. The atypical…
(Only some records are available in English at this moment)
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