bv-cdiResearch Supported by FAPESP
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Scholarships abroad - New Frontiers
The scholarships provide funds under the New Frontiers Program for researchers to accomplish long-term internships in foreign excellence centers in research areas not yet well established in the State of São Paulo.
The recent characterization of the CpG island methylator phenotype (CIMP), observed in 20 to 30 percent of the colorectal cancer samples, confirms the important role of epigenetic mechanisms in the pathogenesis of this tumor type. This phenotype is characterized by the frequent hypermethylation of different regions of the tumor genome. Considering that epigenetic modifications are coordin…
A substantial number of valuable drugs available these days are based upon or inspired in natural products. Among the most useful natural products, polyketides and non-ribosomal peptides share high molecular complexity and therapeutic activity. Though the production of such metabolites is being observed from several organisms as bacteria, fungi, insects, dinoflagellates, mollusks and spon…