European Research Council

• Abstract

  Sickle cell disease (SCD) is a severe disease caused by a single mutation in the beta-globin gene (HBB). The only curative therapy for SCD is allogeneic hematopoietic stem cell transplantation (alloHSCT), however most patients do not have a suitable donor. Gene therapy is a promising curative treatment for SCD. However, which is the best genome editing strategy remains an open question. A…

  Evaluation of functional efficacy and safety of base editing systems correcting the sickle cell mutation, BE.PQ

• Abstract

  This research proposal concerns a one year visit of Prof. Landi to the group of Prof. Goold at Trinity College, Dublin. The two groups already have several common research interests and have been active collaborators for over a year. The goal of this proposal is to consolidate a recently opened front of collaborative research dealing with the connection between thermodynamic uncertainty r…

  Thermodynamics of precision in non-equilibrium quantum devices, BE.PQ

• Abstract

  CrN and CrAlN films are widely used in piston rings in order to improve their working performance in combustion engines. This extensive use is corroborated by their good oxidation resistance, elevated hardness, chemical inertness and wear resistance. The combination of all of these properties is highly attractive for applications in tooling, automotive, aerospace and decorative industries…

  Advanced studies of microstructure-property relationship of Cr-Al-N mono- and multilayers for improved tribological performance in combustion engines, BE.PQ

(Only some records are available in English at this moment)