Genetic aspects of meat production quality, efficiency and sustainability in Nelore breed animals

• Grant number: 17/10630-2
• Support Opportunities: Research Projects - Thematic Grants
• Start date: June 01, 2018
• End date: May 31, 2025
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
• Principal Investigator: Lucia Galvão de Albuquerque
• Grantee: Lucia Galvão de Albuquerque
• Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
• Pesquisadores principais:( Últimos ): Josineudson Augusto Ii de Vasconcelos Silva ; Maria Eugênia Zerlotti Mercadante
• Pesquisadores principais:( Antigos ): Roberto Carvalheiro
• Associated researchers: Alexandre Berndt ; Ana Fabrícia Braga Magalhães ; Camila Urbano Braz ; Daiane Cristina Becker Scalez ; Daniel Guariz Pinheiro ; Diercles Francisco Cardoso ; Fernando Sebastián Baldi Rey ; Gerardo Alves Fernandes Júnior ; Guilherme Jordão de Magalhães Rosa ; Henrique Nunes de Oliveira ; Humberto Tonhati ; Jesus Aparecido Ferro ; Joslaine Noely dos Santos Goncalves Cyrillo ; Juliana de Oliveira Santos Marcatto ; Larissa Fernanda Simielli Fonseca ; Luis Artur Loyola Chardulo ; Rafael Espigolan ; Roberta Carrilho Canesin ; Roberto Carvalheiro ; Rosa Toyoko Shiraishi Frighetto
• Associated research grant(s): 23/02356-9 - 56th congress of the international society for applied ethology, AR.EXT; 18/20026-8 - Multi-user equipment approved in grant 2017/10630-2: server, AP.EMU
• Associated scholarship(s): 23/17818-8 - Genome-wide scan to identify selection signatures and candidate genes associated with enteric methane emission and feed efficiency traits in Nellore cattle using sequencing data, BP.DR; 23/11176-4 - Mapping candidates for lethal haplotypes and genomic regions associated with the occurrence of abortion and pre-weaning mortality in Nellore cattle, BP.MS; 22/11852-7 - Structural equation modeling as a tool to interpret genotype-environment interaction and genome-wide association (GWAS) for growth and reproductive traits in Nellore heifers using whole-genome sequence data, BP.PD; + associated scholarships 21/09942-5 - Variance of gametic diversity estimation for economically important traits of Nellore cattle, BP.DR; 20/03975-6 - Incorporating sequence variants to improve genomic prediction for reproductive traits in Nellore cattle, BP.PD; 19/11738-7 - Phenotypic, genetic correlations and genomic wide association between feed efficiency and enteric methane emission of Nellore cattle, BP.DR; 20/02392-7 - Determination of enteric methane emission from Nelore cattle, BP.TT; 20/02304-0 - Association of ingestive behavior and enteric methane emission in cattle of the Nellore breed, BP.IC; 19/06361-1 - Genotype-environment interaction in Nellore cattle for growth traits and visual scores using sequence data, BP.DR; 19/15397-0 - GENOME WIDE ASSOCIATION STUDY AND DETECTION OF SELECTION SIGNALS IN THE GENOME OF NELORE CATTLE USING SEQUENCE DATA, BP.PD; 19/16732-7 - Bioinformatics application in genome and transcriptome analysis of Nellore cattle, integrating public information, BP.PD; 19/05165-4 - Evaluation of ruminal methane emission flows of Nelore cattle, BP.TT; 18/12504-7 - Phenotyping for methane emission in Nelore males submitted to feed efficiency test, BP.TT; 18/10109-3 - Identification and analysis of genetic variants obtained from the whole-genome sequencing of Nellore bulls, BP.PD; 18/04313-7 - Assessment of inbreeding and study of functional variants using sequenced data in Nelore cattle, BP.PD - associated scholarships

Abstract

In general, Brazilian beef herds need to improve their indexes of efficiency and the final product (meat) quality. Moreover, nowadays, there is a worldwide concern about the animal production sustainability, which could be improved selecting animals with decreased enteric methane emission to the atmosphere. With the evolution of the complete genome sequencing and the decreasing sequencing costs by animal, this technic has been proposed as an alternative to the SNP chips for genomic selection, with various advantages. Therefore, the present project aims to build a data set of enteric methane emission and to use a data set including feed efficiency, meat and carcass quality and reproduction traits already existent to perform genomic studies based in the complete DNA sequence, with the objective of developing technologies to increase the biologic knowledge and the genetic improvement of quality, efficiency and sustainability of Nelore beef cattle production. The following topics will be developed in the project: a) genetic quantitative studies of traits related to enteric methane emission and their genetic associations with feed efficiency traits; b) studies about the accuracy of imputation to the complete DNA sequence from animals genotyped with commercial chips with different SNP numbers and using various methods; c) studies of Nelore genome characterization using sequence data; d) genome wide association studies for economic important traits using genome complete sequence as well as fine mapping candidate genes aiming to identify causal and deleterious mutations for economic traits; e) genomic selection studies for quality, efficiency and sustainability of production traits using sequence data; f) gene expression analysis (transcriptome) for feed efficiency. (AU)

Scientific publications

(43)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MARIN-GARZON, N. A.; MAGALHAES, A. F. B.; SCHMIDT, P. I.; SERNA, M.; FONSECA, L. F. S.; SALATTA, B. M.; FREZARIM, G. B.; FERNANDES-JUNIOR, G. A.; BRESOLIN, T.; CARVALHEIRO, R.; et al. Genome-wide scan reveals genomic regions and candidate genes underlying direct and maternal effects of preweaning calf mortality in Nellore cattle. Genomics, v. 113, n. 3, p. 1386-1395, MAY 2021. (17/10630-2, 18/20026-8)

SAKAMOTO, LEANDRO SANNOMIYA; SOUZA, LUANA LELIS; GIANVECCHIO, SARAH BERNARDES; DE OLIVEIRA, MATHEUS HENRIQUE VARGAS; SILVA, JOSINEUDSON AUGUSTO I. I. DE VASCONCELOS; CANESIN, ROBERTA CARRILHO; BRANCO, RENATA HELENA; BACCAN, MELISSA; BERNDT, ALEXANDRE; DE ALBUQUERQUE, LUCIA GALVAO; et al. Phenotypic association among performance, feed efficiency and methane emission traits in Nellore cattle. PLoS One, v. 16, n. 10, 2021. (18/17313-5, 17/50339-5, 19/11738-7, 17/10630-2)

SCHETTINI, GUSTAVO PIMENTA; PERIPOLLI, ELISA; ALEXANDRE, PAMELA ALMEIDA; DOS SANTOS, WELLINGTON BIZARRIA; CRAVO PEREIRA, ANGELICA SIMONE; DE ALBUQUERQUE, LUCIA GALVAO; BALDI, FERNANDO; CURI, ROGERIO ABDALLAH. Transcriptome Profile Reveals Genetic and Metabolic Mechanisms Related to Essential Fatty Acid Content of Intramuscular Longissimus thoracis in Nellore Cattle. METABOLITES, v. 12, n. 5, p. 18-pg., 2022-05-01. (18/20026-8, 17/10630-2)

ALVES, A. A. C.; ESPIGOLAN, R.; BRESOLIN, T.; COSTA, R. M.; FERNANDES JUNIOR, G. A.; VENTURA, R. V.; CARVALHEIRO, R.; ALBUQUERQUE, L. G.. Genome-enabled prediction of reproductive traits in Nellore cattle using parametric models and machine learning methods. ANIMAL GENETICS, v. 52, n. 1, NOV 2020. (17/10630-2, 09/16118-5, 18/20026-8, 16/24227-2)

SERNA-GARCIA, MARTA; FONSECA, LARISSA FERNANDA SIMIELLI; ROMERO, JOAQUIN JAVIER PANADERO; ASUNCION, JULIAN CARRETERO; SILVA, DANIELLY BERALDO DOS SANTOS; SALATTA, BRUNA MARIA; FREZARIM, GABRIELA BONFA; MERCADANTE, MARIA EUGENIA ZERLOTTI; BONILHA, SARAH FIGUEIREDO MARTINS; FERRO, JESUS APARECIDO; et al. Transcriptome Profiling of the Liver in Nellore Cattle Phenotypically Divergent for RFI in Two Genetic Groups. ANIMALS, v. 13, n. 3, p. 22-pg., 2023-02-01. (18/20026-8, 09/16118-5, 17/10630-2)

SILVA, DANIELLY B. S.; FONSECA, LARISSA F. S.; PINHEIRO, DANIEL G.; MAGALHAES, ANA F. B.; MUNIZ, MARIA M. M.; FERRO, JESUS A.; BALDI, FERNANDO; CHARDULO, LUIS A. L.; SCHNABEL, ROBERT D.; TAYLOR, JEREMY F.; et al. Spliced genes in muscle from Nelore Cattle and their association with carcass and meat quality. SCIENTIFIC REPORTS, v. 10, n. 1, SEP 7 2020. (17/10630-2, 15/16850-9, 09/16118-5, 16/22894-1, 18/20026-8)

TORO OSPINA, ALEJANDRA MARIA; AGUILAR, IGNACIO; VARGAS DE OLIVEIRA, MATHEUS HENRIQUE; CRUZ DOS SANTOS CORREIA, LUIZ EDUARDO; VERCESI FILHO, ANIBAL EUGENIO; ALBUQUERQUE, LUCIA GALVAO; II DE VASCONCELOS SILVA, JOSINEUDSON AUGUSTO. Assessing the accuracy of imputation in the Gyr breed using different SNP panels. GENOME, v. 64, n. 10, p. 893-899, OCT 2021. (15/06686-7, 17/10630-2)

ALVES, ANDERSON ANTONIO CARVALHO; DA COSTA, REBEKA MAGALHAES; FONSECA, LARISSA FERNANDA SIMIELLI; CARVALHEIRO, ROBERTO; VENTURA, RICARDO VIEIRA; ROSA, GUILHERME JORDAO DE MAGALHAES; ALBUQUERQUE, LUCIA GALVAO. A Random Forest-Based Genome-Wide Scan Reveals Fertility-Related Candidate Genes and Potential Inter-Chromosomal Epistatic Regions Associated With Age at First Calving in Nellore Cattle. FRONTIERS IN GENETICS, v. 13, p. 18-pg., 2022-05-18. (18/20026-8, 17/10630-2, 09/16118-5, 16/24227-2)

FERNANDES JUNIOR, GERARDO ALVES; PERIPOLLI, ELISA; SCHMIDT, PATRICIA IANA; CAMPOS, GABRIEL SOARES; MOTA, LUCIO FLAVIO MACEDO; MERCADANTE, MARIA EUGENIA ZERLOTTI; BALDI, FERNANDO; CARVALHEIRO, ROBERTO; DE ALNUQUERQUE, LUCIA GALVAO. Current applications and perspectives of genomic selection in Bos indicus (Nellore) cattle. LIVESTOCK SCIENCE, v. 263, p. 15-pg., 2022-09-01. (18/20026-8, 17/10630-2, 18/10109-3)

FILHO, IVAN CARVALHO; SILVA, DELVAN A.; TEIXEIRA, CAIO S.; SILVA, THALES L.; MOTA, LUCIO F. M.; ALBUQUERQUE, LUCIA G.; CARVALHEIRO, ROBERTO. Heteroscedastic Reaction Norm Models Improve the Assessment of Genotype by Environment Interaction for Growth, Reproductive, and Visual Score Traits in Nellore Cattle. ANIMALS, v. 12, n. 19, p. 24-pg., 2022-10-01. (18/20026-8, 19/06361-1, 17/10630-2)

GIANVECCHIO, SARAH BERNARDES; SAKAMOTO, LEANDRO SANNOMIYA; SOUZA, LUANA LELIS; BENFICA, LORENA FERREIRA; MARCATTO, JULIANA DE OLIVEIRA SANTOS; DE PAULA, EDUARDO MAROSTEGAN; MALHEIROS, JESSICA MORAES; CANESIN, ROBERTA CARRILHO; BONILHA, SARAH FIGUEIREDO MARTINS; DE ALBUQUERQUE, LUCIA GALVAO; et al. Is apparent digestibility associated with residual feed intake and enteric methane emission in Nellore cattle?. REVISTA BRASILEIRA DE ZOOTECNIA-BRAZILIAN JOURNAL OF ANIMAL SCIENCE, v. 53, p. 14-pg., 2024-01-01. (19/07626-9, 17/10630-2, 22/12669-1, 17/50339-5, 18/17313-5, 19/11738-7)

FILHO, IVAN CARVALHO; ARIKAWA, LEONARDO M.; MOTA, LUCIO F. M.; CAMPOS, GABRIEL S.; FONSECA, LARISSA F. S.; FERNANDES, GERARDO A.; SCHENKEL, FLAVIO S.; LOURENCO, DANIELA; SILVA, DELVAN A.; TEIXEIRA, CAIO S.; et al. Genome-wide association study considering genotype-by-environment interaction for productive and reproductive traits using whole-genome sequencing in Nellore cattle. BMC Genomics, v. 25, n. 1, p. 16-pg., 2024-06-20. (17/10630-2, 18/20026-8, 20/14846-2, 19/06361-1, 22/11852-7)

MOTA, LUCIO F. M.; ARIKAWA, LEONARDO M.; NASNER, SINDY L. C.; SCHMIDT, PATRICIA I.; CARVALHEIRO, ROBERTO; OLIVEIRA, HENRIQUE N.; ALBUQUERQUE, LUCIA G.. Evaluation of the productive and reproductive performance of sexual precocity at different ages in Nellore heifers. Theriogenology, v. 230, p. 9-pg., 2024-09-19. (18/20026-8, 22/11852-7, 17/10630-2)

MOTA, LUCIO F. M.; ARIKAWA, LEONARDO M.; SANTOS, SAMUEL W. B.; FERNANDES, GERARDO A.; ALVES, ANDERSON A. C.; ROSA, GUILHERME J. M.; MERCADANTE, MARIA E. Z.; CYRILLO, JOSLAINE N. S. G.; CARVALHEIRO, ROBERTO; ALBUQUERQUE, LUCIA G.. Benchmarking machine learning and parametric methods for genomic prediction of feed efficiency-related traits in Nellore cattle. SCIENTIFIC REPORTS, v. 14, n. 1, p. 14-pg., 2024-03-17. (09/16118-5, 17/10630-2, 18/20026-8, 16/24228-9, 17/13411-0)

ARIKAWA, LEONARDO MACHESTROPA; MOTA, LUCIO FLAVIO MACEDO; SCHMIDT, PATRICIA IANA; FREZARIM, GABRIELA BONFA; FONSECA, LARISSA FERNANDA SIMIELLI; MAGALHAES, ANA FABRICIA BRAGA; SILVA, DELVAN ALVES; CARVALHEIRO, ROBERTO; CHARDULO, LUIS ARTUR LOYOLA; DE ALBUQUERQUE, LUCIA GALVAO. Genome-wide scans identify biological and metabolic pathways regulating carcass and meat quality traits in beef cattle. MEAT SCIENCE, v. 209, p. 13-pg., 2023-12-05. (17/10630-2)

DOS SANTOS, THAIS CRISTINA FERREIRA; SILVA, EVANDRO NEVES; FREZARIM, GABRIELA BONFA; SALATTA, BRUNA MARIA; BALDI, FERNANDO; FONSECA, LARISSA FERNANDA SIMIELLI; DE ALBUQUERQUE, LUCIA GALVAO; MUNIZ, MARIA MALANE MAGALHAES; SILVA, DANIELLY BERALDO DOS SANTOS. Identification of cis-sQTL demonstrates genetic associations and functional implications of inflammatory processes in Nelore cattle muscle tissue. Mammalian Genome, v. N/A, p. 12-pg., 2025-01-18. (18/20026-8, 17/10630-2)

DOS SANTOS, THAIS CRISTINA FERREIRA; SILVA, EVANDRO NEVES; FREZARIM, GABRIELA BONFA; SALATTA, BRUNA MARIA; BALDI, FERNANDO; FONSECA, LARISSA FERNANDA SIMIELLI; DE ALBUQUERQUE, LUCIA GALVAO; MUNIZ, MARIA MALANE MAGALHAES; SILVA, DANIELLY BERALDO DOS SANTOS. Cis-eQTL analysis reveals genes involved in biological processes of the immune system in Nelore cattle. Gene, v. 937, p. 9-pg., 2024-12-04. (18/20026-8, 17/10630-2)

RODRIGUES, GUSTAVO R. D.; CYRILLO, JOSLAINE N. S. G.; MOTA, LUCIO F. M.; SCHMIDT, PATRICIA I.; VALENTE, JULIA P. S.; OLIVEIRA, EDUARDA S.; ALBUQUERQUE, LUCIA G.; BRITO, LUIZ F.; MERCADANTE, MARIA E. Z.. Effect of genomic regions harboring putative lethal haplotypes on reproductive performance in closed experimental selection lines of Nellore cattle. SCIENTIFIC REPORTS, v. 15, n. 1, p. 15-pg., 2025-02-03. (18/20026-8, 24/01909-7, 24/05697-4, 21/09942-5, 17/10630-2, 23/11176-4, 22/11852-7, 17/50339-5)

ARIKAWA, LEONARDO MACHESTROPA; MOTA, LUCIO FLAVIO MACEDO; SCHMIDT, PATRICIA IANA; SALATTA, BRUNA MARIA; NASNER, SINDY LILIANA CAIVIO; SILVA NETO, JOAO BARBOSA DA; FONSECA, LARISSA FERNANDA SIMIELLI; MAGALHAES, ANA FABRICIA BRAGA; SILVA, DELVAN ALVES; CARVALHEIRO, ROBERTO; et al. Genetic Parameter Estimates for Carcass and Meat Quality Traits and Their Genetic Associations With Sexual Precocity Indicator Traits in Nellore Cattle. JOURNAL OF ANIMAL BREEDING AND GENETICS, v. N/A, p. 13-pg., 2025-02-05. (17/10630-2)

SOUZA, LUANA LELIS; DOMINGUEZ-CASTANO, PABLO; GIANVECCHIO, SARAH BERNARDES; SAKAMOTO, LEANDRO SANNOMIYA; RODRIGUES, GUSTAVO ROBERTO DIAS; SOARES, TAINARA LUANA DA SILVA; BONILHA, SARAH FIGUEIREDO MARTINS; MARCATTO, JULIANA DE OLIVEIRA SANTOS; ALBUQUERQUE, LUCIA GALVAO; SILVA, JOSINEUDSON AUGUSTO I. I. VASCONCELOS; et al. Heritability estimates and genome-wide association study of methane emission traits in Nellore cattle. JOURNAL OF ANIMAL SCIENCE, v. 102, p. 10-pg., 2024-07-27. (17/10630-2, 18/20026-8, 23/11176-4, 17/50339-5, 18/17313-5, 19/11738-7)

MUNIZ, MALANE M.; SIMIELLI FONSECA, LARISSA FERNANDA; CANOVAS, ANGELA; DOS SANTOS SILVA, DANIELLY BERALDO; FERRO, JESUS APARECIDO; CHARDULO, ARTUR LOYOLA; BALDI, FERNANDO; DE ALBUQUERQUE, LUCIA GALVAO. Structural variants affecting mRNAs isoforms splice sites associated with marbling in Nellore cattle. JOURNAL OF ANIMAL SCIENCE, v. 98, p. 2-pg., 2020-11-01. (18/11154-2, 11/21241-0, 09/16118-5, 18/20026-8, 17/10630-2)

MOTA, LUCIO F. M.; SANTOS, SAMUEL W. B.; JUNIOR, GERARDO A. FERNANDES; BRESOLIN, TIAGO; MERCADANTE, MARIA E. Z.; SILVA, JOSINEUDSON A. V.; CYRILLO, JOSLAINE N. S. G.; MONTEIRO, FABIO M.; CARVALHEIRO, ROBERTO; ALBUQUERQUE, LUCIA G.. Meta-analysis across Nellore cattle populations identifies common metabolic mechanisms that regulate feed efficiency-related traits. BMC Genomics, v. 23, n. 1, p. 12-pg., 2022-06-07. (09/16118-5, 17/10630-2, 17/13411-0, 16/24228-9)

MAGALHAES MUNIZ, MARIA MALANE; SIMIELLI FONSECA, LARISSA FERNANDA; BECKER SCALEZ, DAIANE CRISTINA; VEGA, AROA SUAREZ; DOS SANTOS SILVA, DANIELLY BERALDO; FERRO, JESUS APARECIDO; CHARDULO, ARTUR LOYOLA; BALDI, FERNANDO; CANOVAS, ANGELA; DE ALBUQUERQUE, LUCIA GALVAO. Characterization of novel lncRNA muscle expression profiles associated with meat quality in beef cattle. EVOLUTIONARY APPLICATIONS, v. 15, n. 4, p. 13-pg., 2022-03-25. (18/11154-2, 18/20026-8, 09/16118-5, 17/10630-2, 11/21241-0)

MAGALHAES MUNIZ, MARIA MALANE; SIMIELLI FONSECA, LARISSA FERNANDA; DOS SANTOS SILVA, DANIELLY BERALDO; DE OLIVEIRA, HINAYAH ROJAS; BALDI, FERNANDO; CHARDULO, ARTUR LOYOLA; FERRO, JESUS APARECIDO; CANOVAS, ANGELA; DE ALBUQUERQUE, LUCIA GALVAO. Identification of novel mRNA isoforms associated with meat tenderness using RNA sequencing data in beef cattle. MEAT SCIENCE, v. 173, MAR 2021. (18/20026-8, 11/21241-0, 18/11154-2, 09/16118-5, 17/10630-2)

SOARES VALENTE, JULIA DE PAULA; DE-SOUSA, KAROLINI TENFFEN; DENIZ, MATHEUS; BONILHA, SARAH FIGUEIREDO MARTINS; MERCADANTE, MARIA EUGENIA ZERLOTTI; DIAS, LAILA TALARICO. Heritability and genetic association of social organization traits with feeding behavior, feed efficiency and growth in Bos indicus. APPLIED ANIMAL BEHAVIOUR SCIENCE, v. 265, p. 6-pg., 2023-06-13. (17/50339-5, 17/10630-2)

FERNANDES JUNIOR, GERARDO ALVES; DE OLIVEIRA, HENRIQUE NUNES; CARVALHEIRO, ROBERTO; CARDOSO, DIERCLES FRANCISCO; FONSECA, LARISSA FERNANDA SIMIELLI; VENTURA, RICARDO VIEIRA; DE ALBUQUERQUE, LUCIA GALVAO. Whole-genome sequencing provides new insights into genetic mechanisms of tropical adaptation in Nellore (Bos primigenius indicus). SCIENTIFIC REPORTS, v. 10, n. 1, JUN 10 2020. (09/16118-5, 19/12434-1, 18/10109-3, 18/20026-8, 17/10630-2)

FREZARIM, GABRIELA B.; FONSECA, LARISSA F. S.; SALATTA, BRUNA M.; SILVA, DANIELLY B. S.; BRESOLIN, TIAGO; SENO, LEONARDO DE OLIVEIRA; BARUFATTI, ALEXEIA; FERRO, JESUS APARECIDO; ALBUQUERQUE, LUCIA GALVAO. Genes and proteins associated with ribeye area and meat tenderness in a commercial Nellore cattle population. GENOME, v. 65, n. 4, p. 12-pg., 2022-04-01. (18/20026-8, 17/10630-2, 16/23937-6)

CARVALHEIRO, ROBERTO; COSTILLA, ROY; NEVES, HAROLDO H. R.; ALBUQUERQUE, LUCIA G.; MOORE, STEPHEN; HAYES, BEN J.. Unraveling genetic sensitivity of beef cattle to environmental variation under tropical conditions. GENETICS SELECTION EVOLUTION, v. 51, JUN 20 2019. (17/18415-3, 17/10630-2)

FERNANDES JUNIOR, GERARDO A.; CARVALHEIRO, ROBERTO; DE OLIVEIRA, HENRIQUE N.; SARGOLZAEI, MEHDI; COSTILLA, ROY; VENTURA, RICARDO V.; FONSECA, LARISSA F. S.; NEVES, HAROLDO H. R.; HAYES, BEN J.; DE ALBUQUERQUE, LUCIA G.. Imputation accuracy to whole-genome sequence in Nellore cattle. GENETICS SELECTION EVOLUTION, v. 53, n. 1, MAR 12 2021. (17/10630-2, 19/12434-1, 09/16118-5, 18/10109-3, 18/20026-8)

NEVES, HAROLDO H. R.; VARGAS, GIOVANA; BRITO, LUIZ F.; SCHENKEL, FLAVIO S.; ALBUQUERQUE, LUCIA G.; CARVALHEIRO, ROBERTO. Genetic and genomic analyses of testicular hypoplasia in Nellore cattle. PLoS One, v. 14, n. 1, JAN 24 2019. (17/10630-2)

ALVES, JACKELINE SANTOS; DIAZ, IARA DEL PILAR SOLAR; DA CRUZ, VALDECY APARECIDA ROCHA; BASTOS, MARISA SILVA; DE OLIVEIRA, LOUISE SARMENTO MARTINS; DE ALBUQUERQUE, LUCIA GALVAO; DE CAMARGO, GREGORIO MIGUEL FERREIRA; COSTA, RAPHAEL BERMAL. The effect of mitochondrial DNA polymorphisms on cattle reproduction. MOLECULAR BIOLOGY REPORTS, v. 48, n. 1, JAN 2021. (18/20026-8, 17/10630-2, 09/16118-5)

BENFICA, LORENA FERREIRA; SAKAMOTO, LEANDRO SANNOMIYA; BRAGA MAGALHAES, ANA FABRICIA; VARGAS DE OLIVEIRA, MATHEUS HENRIQUE; DE ALBUQUERQUE, LUCIA GALVAO; CAVALHEIRO, ROBERTO; BRANCO, RENATA HELENA; DOS SANTOS GONCALVES CYRILLO, JOSLAINE NOELY; ZERLOTTI MERCADANTE, MARIA EUGENIA. Genetic association among feeding behavior, feed efficiency, and growth traits in growing indicine cattle. JOURNAL OF ANIMAL SCIENCE, v. 98, n. 11, NOV 2020. (17/10630-2, 18/04313-7, 17/50339-5, 18/17313-5)

BENFICA, LORENA F.; BRITO, LUIZ F.; DO BEM, RICARDO D.; DE OLIVEIRA, LETICIA F.; MULIM, HENRIQUE A.; BRAGA, LARISSA G.; CYRILLO, JOSLAINE N. S. G.; BONILHA, SARAH F. M.; MERCADANTE, MARIA EUGENIA Z.. Detection and characterization of copy number variation in three differentially-selected Nellore cattle populations. FRONTIERS IN GENETICS, v. 15, p. 14-pg., 2024-04-17. (17/50339-5, 17/10630-2)

SCHMIDT, PATRICIA IANA; MOTA, LUCIO FLAVIO MACEDO; FONSECA, LARISSA FERNANDA SIMIELLI; DOS SANTOS SILVA, DANIELLY BERALDO; FREZARIM, GABRIELA BONFA; ARIKAWA, LEONARDO MACHESTROPA; DE ABREU SANTOS, DANIEL JORDAN; MAGALHES, ANA FABRICIA BRAGA; COLE, JOHN BRUCE; CARVALHEIRO, ROBERTO; et al. Identification of candidate lethal haplotypes and genomic association with post-natal mortality and reproductive traits in Nellore cattle. SCIENTIFIC REPORTS, v. 13, n. 1, p. 12-pg., 2023-06-27. (09/16118-5, 17/10630-2, 18/20026-8, 18/17812-1, 19/10123-9, 21/09942-5)

SALATTA, BRUNA MARIA; MUNIZ, MARIA MALANE MAGALHAES; FONSECA, LARISSA FERNANDA SIMIELLI; MOTA, LUCIO FLAVIO MACEDO; TEIXEIRA, CAIO DE SOUZA; FREZARIM, GABRIELA BONFA; SERNA-GARCIA, MARTA; ARIKAWA, LEONARDO MACHESTROPA; SCHMIDT, PATRICIA IANA; NASNER, SINDY LILIANA CAIVIO; et al. Differentially expressed messenger RNA isoforms in beef cattle skeletal muscle with different fatty acid profiles. MEAT SCIENCE, v. 222, p. 14-pg., 2025-01-10. (09/16118-5, 17/10630-2, 11/21241-0)

RODRIGUES, GUSTAVO R. D.; BRITO, LUIZ F.; MOTA, LUCIO F. M.; CYRILLO, JOSLAINE N. S. G.; VALENTE, JULIA P. S.; BENFICA, LORENA F.; NETO, JOAO B. SILVA; BORGES, MARCELO S.; MONTEIRO, FABIO M.; EL FARO, LENIRA; et al. Genome-wide association studies and functional annotation of pre-weaning calf mortality and reproductive traits in Nellore cattle from experimental selection lines. BMC Genomics, v. 25, n. 1, p. 17-pg., 2024-12-18. (24/01909-7, 24/05697-4, 17/10630-2, 23/11176-4, 22/11852-7, 17/50339-5)

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