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Genetic aspects of meat production quality, efficiency and sustainability in Nelore breed animals

Grant number: 17/10630-2
Support type:Research Projects - Thematic Grants
Duration: June 01, 2018 - May 31, 2023
Field of knowledge:Agronomical Sciences - Animal Husbandry
Principal Investigator:Lucia Galvão de Albuquerque
Grantee:Lucia Galvão de Albuquerque
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal, SP, Brazil
Co-Principal Investigators:Josineudson Augusto Ii de Vasconcelos Silva ; Maria Eugênia Zerlotti Mercadante ; Roberto Carvalheiro
Assoc. researchers:Alexandre Berndt ; Ana Fabrícia Braga Magalhães ; Camila Urbano Braz ; Daiane Cristina Becker Scalez ; Daniel Guariz Pinheiro ; Diercles Francisco Cardoso ; Fernando Sebastián Baldi Rey ; Gerardo Alves Fernandes Júnior ; Guilherme Jordão de Magalhães Rosa ; Henrique Nunes de Oliveira ; Humberto Tonhati ; Jesus Aparecido Ferro ; Joslaine Noely dos Santos Goncalves Cyrillo ; Larissa Fernanda Simielli Fonseca ; Luis Artur Loyola Chardulo ; Rafael Espigolan ; Roberta Carrilho Canesin ; Rosa Toyoko Shiraishi Frighetto
Associated grant(s):18/20026-8 - Multi-user equipment approved in grant 2017/10630-2: server, AP.EMU
Associated scholarship(s):18/12504-7 - Phenotyping for methane emission in Nelore males submitted to feed efficiency test, BP.TT
18/10109-3 - Identification and analysis of genetic variants obtained from the whole-genome sequencing of Nellore bulls, BP.PD
18/04313-7 - Assessment of inbreeding and study of functional variants using sequenced data in Nelore cattle, BP.PD


In general, Brazilian beef herds need to improve their indexes of efficiency and the final product (meat) quality. Moreover, nowadays, there is a worldwide concern about the animal production sustainability, which could be improved selecting animals with decreased enteric methane emission to the atmosphere. With the evolution of the complete genome sequencing and the decreasing sequencing costs by animal, this technic has been proposed as an alternative to the SNP chips for genomic selection, with various advantages. Therefore, the present project aims to build a data set of enteric methane emission and to use a data set including feed efficiency, meat and carcass quality and reproduction traits already existent to perform genomic studies based in the complete DNA sequence, with the objective of developing technologies to increase the biologic knowledge and the genetic improvement of quality, efficiency and sustainability of Nelore beef cattle production. The following topics will be developed in the project: a) genetic quantitative studies of traits related to enteric methane emission and their genetic associations with feed efficiency traits; b) studies about the accuracy of imputation to the complete DNA sequence from animals genotyped with commercial chips with different SNP numbers and using various methods; c) studies of Nelore genome characterization using sequence data; d) genome wide association studies for economic important traits using genome complete sequence as well as fine mapping candidate genes aiming to identify causal and deleterious mutations for economic traits; e) genomic selection studies for quality, efficiency and sustainability of production traits using sequence data; f) gene expression analysis (transcriptome) for feed efficiency. (AU)