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Institutional research development plan of the Instituto Adolfo Lutz (PDIp)

Grant number: 17/50333-7
Support type:Research Grants - State Research Institutes Modernization Program
Duration: April 01, 2018 - March 31, 2022
Field of knowledge:Health Sciences - Collective Health - Public Health
Principal researcher:José Eduardo Tolezano
Grantee:José Eduardo Tolezano
Home Institution: Instituto Adolfo Lutz (IAL). Coordenadoria de Controle de Doenças (CCD). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
Pesquisadores principais:
( Atuais )
André Gustavo Tempone Cardoso ; Carlos Roberto Prudencio ; Marcia de Souza Carvalho Melhem ; Maria Do Carmo Sampaio Tavares Timenetsky ; Paula Ordonhez Rigato
Pesquisadores principais:
( Anteriores )
José Eduardo Tolezano
Associated grant(s):18/14384-9 - Identification and characterization of acute cases of Human Immunodeficiency Virus (HIV-1) infection, AP.PP
18/25889-4 - Technological innovations in health for the diagnosis and control of Visceral Leishmaniosis in the municipality of Bauru, State of São Paulo, Brazil, AP.PP
18/21192-9 - Multi-User Equipment approved in grant 2017/50333-7: MALDI-TOF, AP.EMU
18/21191-2 - Multi-User Equipment approved in grant 2017/50333-7: flow cytometer, AP.EMU
18/21193-5 - Multi-user equipment approved in grant 2017/50333-7: genetic analyzer, AP.EMU
Associated scholarship(s):21/02608-2 - Construction and selection of a library of scFv monoclonal antibodies against SARS-CoV-2 spike protein by phage display technology, BP.PD
21/01496-6 - Investigation of CD4 and CD8 T cells profiles using multicolour flow cytometry to biomarkers identification on latent tuberculosis, BP.MS
20/03637-3 - Study of new drug candidates for neglected protozoan diseases, BP.PD
19/22246-8 - The use of geotechnologies in health: spatial analysis of laboratory-based surveillance phenomena: Leishmaniases in São Paulo State, Brazil, BP.PD
18/18996-9 - Cryptic Candida species among bloodstream isolates: identification and susceptibility pattern to azole drugs, BP.MS


IAL has established itself as a reference institution in Public Health, developing scientific research and performing analytical procedures for diagnostic elucidation and sanitary control, rapidly addressing the demands of Health Surveillance of the different regions of the State of Sao Paulo and other units of the federation. The data regarding the IAL scientific-technical production (services, publications, continuing education, and professional training) in the last 5 years have indicated that the institution performance is consistent with its mission, as part of the Health Surveillance System of the State of Sao Paulo, and convergent to the priorities established on 2016-2019 PES (State Plan for Health), producing satisfactory results in the areas of concentration of such demands. The IAL Research Institutional Development Plan intends to be an auxiliary resource for planning and management, aiming to encourage the development of laboratory researches and contribute to the integrity of government actions for the protection, prevention and promotion of health, and improvement of the quality of life for the population. The chosen strategy lies on the development of technological units, enabling the implementation of advanced methodologies for the study of incidence and biological diversity of pathogens, identification of biomarkers in health events/diseases, and assessment of food/water safety of relevance to Public Health. The research grants and infrastructure resources requested in this plan will be allocated for structuring of the following units: bioinformatics, georeferencing, and next-generation sequencing, and also to enhance units such as flow cytometry, chromatography, and spectrometry. Together, these units will allow IAL to offer better conditions for the provision of public services and generation of research in its operational field. With the accomplishment of the projects presented here, we expect to establish new research lines, gain expertise, generate high quality human resources, and strengthen competencies to keep IAL as a Center of Excellence and Reference in Epidemiological, Sanitary and Environmental Surveillance, operating at the forefront of science, technology and resulting in suitable technological solutions to the challenges in Public Health. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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