Scientific, technological and infrastructure qualification in radiopharmaceuticals, radiation and entrepreneurship for health purposes (PDIp)

• Grant number: 17/50332-0
• Support Opportunities: Research Grants - State Research Institutes Modernization Program
• Start date: April 01, 2018
• End date: March 31, 2023
• Field of knowledge: Physical Sciences and Mathematics - Chemistry
• Principal Investigator: Marcelo Linardi
• Grantee: Marcelo Linardi
• Host Institution: Instituto de Pesquisas Energéticas e Nucleares (IPEN). Secretaria de Desenvolvimento Econômico (São Paulo - Estado). São Paulo , SP, Brazil
• Pesquisadores principais: Ademar Benévolo Lugão ; Artur Wilson Carbonari ; Elaine Bortoleti de Araújo ; Maria Elisa Chuery Martins Rostelato ; Monica Beatriz Mathor ; Niklaus Ursus Wetter ; Nilson Dias Vieira Junior
• Associated research grant(s): 18/25754-1 - Multi user equipment approved in grant FAPESP 2017/50332-0: digital mammograph, AP.EMU; 19/24085-1 - Development and characterization of nanoparticulate biomaterials for therapeutic and diagnostic applications in medicine, AV.EXT; 19/17154-7 - Development and characterization of nanoparticulated biomaterials for medicine therapy and diagnostic applications, AV.EXT; + associated grants 18/25961-7 - Laser particle acceleration and applications, AP.R SPRINT; 18/19251-7 - Multi-User Equipment approved in grant 2017/50332-0: ASAP 2020 plus surface area analyzer, volume and pore area, AP.EMU; 18/19240-5 - Multi-user equipment approved in grant 2017-50332-0: STM-AFM Raman SNOM analysis system, AP.EMU - associated grants
• Associated scholarship(s): 22/07199-6 - Characterization of nanocomposites and their interaction with cellular tissue by SNOM techniques for the purpose of new drugs, BP.PD; 21/13737-8 - Acceleration of laser particles in the Scientific, Technological and Infrastructure Training program in Radiopharmaceuticals and Entrepreneurship at the Service of Health., BP.PD; 19/15154-0 - Smart immunotherapeutic gold and palladium nanoparticles functionalized with immunomodulatory phytochemicals (mangiferin, resveratrol, piceatanol, naringin, silibilin, and astringin) and their use as radiosensitizers for tumor ablation therapy, BP.PD; + associated scholarships 19/15620-0 - Tuning MFe2O4 (M=Co,Ni) nanoparticles for in vivo biomedical applications: Doping with rare earths and biocompatible coating, BP.PD; 19/15640-1 - The role of Tissue Engineering on the development of in vitro models for biocompatibility tests and biological assessment, BP.PD; 18/18526-2 - Radioactive Nanosource for Use in Brachytherapy, BP.PD; 19/10110-4 - Studies of adequacy of radiolabeling of PSMA-1007 with fluorine-18 : validation of the analytical methodology and pre-clinical evaluation in the diagnosis of prostate cancer, BP.MS; 19/04172-7 - Pharmacotechnical development of DOTATATO lyophilized kit for 68Ga labeling and preclinical evaluation, BP.DR; 18/18928-3 - Development and Application of Theranostic Biomaterials: Evaluation of Cellular Response to Fluorescent Nanoparticles of Lanthanide and Magnesium-doped Calcium Phosphates and its Applicability as Non-Viral Vectors for Gene Therapy, BE.PQ; 18/13096-0 - Study for implantation of the radiopharmaceutical FES-18F process production in an automated system: process validation and analytical methods approach, BP.MS; 18/12965-4 - Obtaining and evaluating the applicability in the treatment of Prostate Cancer of the PSMA-617 kit for prompt radiolabeling with lutetium-177, BP.DR - associated scholarships

Abstract

The Scientific and Technological Qualification refers to the necessary adaptation to the development of new radiopharmaceuticals, specifically in the phase of scheduling until pilot, within the required quality standards. In addition, one must consider safety issues for manipulation of high radioactive activities, compatible with the scale of industrial production, making it possible to close development cycle for new products, destined to conduct clinical studies in order to demonstrate their efficacy and safety. In addition, this capacitation includes the development of advanced laboratory practices for the chemical and isotopic qualification of radiopharmaceuticals and nanobiomaterials, for health application, via mass spectrometry technique, among others. Radiopharmaceuticals produced at IPEN need assessment by pre-clinical tests for ANVISA approval. This project also aims to carry out research to evaluate the cytotoxic and genotoxic activity of new radiopharmaceutical candidates, as well as to improve radiation detection systems and the processes associated with radiotherapy, nuclear medicine and radio diagnosis, using high performance computing. Considering the qualification in R&D Infrastructure, the project aims to create a nucleus of imaging studies in molecules, cells, tissues and nanoparticles associated to biological processes at IPEN, unprecedented in the country, by SNOM and micro-FTIR, for innovative use in medicine. The proposed techniques will allow mapping of ultrastructural and cellular changes before and after a given treatment, by either laser, nanoparticules, brachytherapy, or radiopharmaceutical. On another front of R&D, the objective is to demonstrate the feasibility of the acceleration of charged particles (electrons/protons/hadrons) in compact systems with lower cost, compared to conventional technologies of acceleration, aiming to proton therapy for nuclear medicine. Closing the virtuous cycle of Innovation and Entrepreneurship, the project aims to improve the management of knowledge and intellectual property generated at IPEN and its interface with the productive sector, in specific actions. (AU)

Scientific publications

(63)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SANTOS, SUZILENE V.; COSTA, CLEIDILANE S.; PARAGUASSU, WALDECI; SILVA, CRYSTIAN W. C.; OTUBO, LARISSA; SOUZA, KATIUSSE S.; CORREA, BRUNO S.; MIRANDA-FILHO, ARNALDO A.; FERREIRA, WANDERSON L.; CARBONARI, ARTUR W.; et al. Synthesis and Local Characterization of CoO Nanoparticles in Distinct Phases: Unveiling Polymorphic Structures. ACS OMEGA, v. 9, n. 42, p. 12-pg., 2024-10-10. (17/50332-0, 14/14001-1, 14/50279-4, 20/15230-5)

FAROOQ, SAJID; ZEZELL, DENISE MARIA. Advances in Metallic-Based Localized Surface Plasmon Sensors for Enhanced Tropical Disease Detection: A Comprehensive Review. Plasmonics, v. 19, n. 4, p. 22-pg., 2023-11-21. (21/00633-0, 17/50332-0)

MUNOZ, PATRICIO; ILAVSKY, JAN; NEWVILLE, MATTHEW; WETTER, NIKLAUS U.; LOURENCO, RAFAEL ANDRE; DE ANDRADE, MARCELO BARBOSA; MARTINS, TEREZA S.; DIPOLD, JESSICA; FREITAS, ANDERSON Z.; CIDES DA SILVA, LUIS CARLOS; et al. (U)SAXS characterization of porous microstructure of chert: insights into organic matter preservation. JOURNAL OF APPLIED CRYSTALLOGRAPHY, v. 56, p. 15-pg., 2023-12-01. (13/03487-8, 19/08582-5, 18/19240-5, 17/50332-0)

SILVA, CRYSTIAN W. C.; CABRERA-PASCA, GABRIEL A.; SOUZA, KATIUSSE S.; COSTA, CLEIDILANE S.; COSTA, MESSIAS S.; CORREA, BRUNO S.; FERREIRA, WANDERSON L.; FREITAS, RAFAEL S.; CARBONARI, ARTUR W.; OTUBO, LARISSA. Investigation of Ni/Ni₃C Nanoparticle Synthesis for Application as a Catalyst in Carbon Nanostructure Growth. ACS APPLIED NANO MATERIALS, v. 6, n. 22, p. 16-pg., 2023-11-08. (17/50332-0, 14/14001-1, 14/50279-4, 20/15230-5)

CORREA, BRUNO S.; COSTA, MESSIAS S.; CABRERA-PASCA, GABRIEL A.; SENA, CLEIDILANE; PINTO, RAFAEL H.; SILVA, ANA PAULA S.; CARVALHO JUNIOR, RAUL N.; ISHIDA, LINA; RAMON, JONATHAN G. A.; FREITAS, RAFAEL S.; et al. High-saturation magnetization in small nanoparticles of Fe3O4 coated with natural oils. JOURNAL OF NANOPARTICLE RESEARCH, v. 22, n. 3, MAR 6 2020. (15/16191-5, 17/50332-0)

FAROOQ, SAJID; GERMANO, GLEICE; STANCARI, KLEBER ADRIANI; RAFFAELI, ROCIO; CROCE, MARIA VIRGINIA; CROCE, ADELA E.; ZEZELL, DENISE MARIA; IEEE. A 3D discriminant analysis for Hyperspectral FTIR images. 2023 INTERNATIONAL CONFERENCE ON OPTICAL MEMS AND NANOPHOTONICS, OMN AND SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE, SBFOTON IOPC, v. N/A, p. 2-pg., 2023-01-01. (21/00633-0, 17/50332-0)

PERES, DANIELLA LUMARA; FAROOQ, SAJID; RAFFAELI, ROCIO; CROCE, MARIA VIRGINIA; CROCE, ADELA E.; ZEZELL, DENISE MARIA; IEEE. Identification of basal cell carcinoma skin cancer using FTIR and Machine learning. 2023 INTERNATIONAL CONFERENCE ON OPTICAL MEMS AND NANOPHOTONICS, OMN AND SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE, SBFOTON IOPC, v. N/A, p. 2-pg., 2023-01-01. (21/00633-0, 17/50332-0)

FAROOQ, SAJID; PERES, DANIELLA L. PRIME UMARA; CAIXETA, DOUGLAS CARVALHO; LIMA, CASSIO; DA SILVA, ROBINSON SABINO; ZEZELL, DENISE MARIA; IEEE. Monitoring changes in urine from diabetic rats using ATR-FTIR and Machine Learning. 2023 INTERNATIONAL CONFERENCE ON OPTICAL MEMS AND NANOPHOTONICS, OMN AND SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE, SBFOTON IOPC, v. N/A, p. 2-pg., 2023-01-01. (21/00633-0, 17/50332-0)

RODRIGUES, PRISCILA S.; BURIMOVA, ANASTASIA; SALES, TATIANE S. N.; FILHO, ARNALDO A. M.; OTUBO, LARISSA; SAXENA, RAJENDRA N.; CARBONARI, ARTUR W.. The effect of Er doping on local structure of magnetite nanoparticles. HYPERFINE INTERACTIONS, v. 242, n. 1, p. 6-pg., 2021-12-01. (19/15620-0, 17/50332-0)

ZANINI, NATHALIA A.; RABELO, THAIS F.; ZAMATARO, CLAUDIA B.; CARAMEL-JUVINO, AMANDA; ANA, PATRICIA A.; ZEZELL, DENISE M.. Morphological, optical, and elemental analysis of dental enamel after debonding laminate veneer with Er,Cr:YSGGlaser: A pilot study. MICROSCOPY RESEARCH AND TECHNIQUE, v. 84, n. 3, p. 489-498, MAR 2021. (17/50332-0, 05/51689-2)

BORDON, CAMILA D. S.; DIPOLD, JESSICA; FREITAS, ANDERSON Z.; WETTER, NIKLAUS U.; DE ROSSI, WAGNER; KASSAB, LUCIANA R. P.. A new double-line waveguide architecture for photonic applications using fs laser writing in Nd3+ doped GeO2-PbO glasses. Optical Materials, v. 129, p. 6-pg., 2022-07-01. (13/26113-6, 17/50332-0, 18/19240-5, 16/02326-9, 17/10765-5, 19/06334-4)

DEL VALLE, MATHEUS; DOS SANTOS, MOISES OLIVEIRA; DOS SANTOS, SOFIA NASCIMENTO; BERNARDES, EMERSON SOARES; ZEZELL, DENISE MARIA; IEEE. Evaluation of machine learning models for the classification of breast cancer hormone receptors using micro-FTIR images. 2021 SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE (SBFOTON IOPC), v. N/A, p. 3-pg., 2021-01-01. (05/51689-2, 17/50332-0)

ANDRADE, MAIRA FRANCO; SARDO, ARIANE VENZON NAIA; BENETTI, CAROLINA; SICCHIERI, LETICIA BONFANTE; CORREA, LUCIANA; ZEZELL, DENISE MARIA. Comparison of Two Light Wavelengths (lambda = 660 nm and lambda = 780 nm) in the Repair Process of Oral Mucositis Induced by Ionizing Radiation: Clinical and Microscopic Evaluations in Rats. PHOTONICS, v. 10, n. 1, p. 13-pg., 2023-01-01. (17/07519-2, 17/50332-0, 13/26113-6)

VIEIRA, DANIEL PEREZ. Three-dimensional cellular culture system for testing of biological effects of radiations in tumoral and non-tumoral models. BIOPHYSICAL REVIEWS, v. 13, n. 6, p. 1-pg., 2021-12-01. (17/50332-0)

SARDO, ARIANE VENZON NAIA; ANDRADE, MAIRA FRANCO; FIGUEIREDO, ANAELIZA; ROSIN, FLAVIA CRISTINA PERILLO; CORREA, LUCIANA; ZEZELL, DENISE MARIA. Does Photobiomodulation Affects CK10 and CK14 in Oral Mucositis Radioinduced Repair?. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 24, p. 9-pg., 2022-12-01. (21/00633-0, 17/50332-0, 13/26113-6)

FAROOQ, SAJID; DEL-VALLE, MATHEUS; SANTOS, SOFIA NASCIMENTO DOS; BERNARDES, EMERSON SOARES; ZEZELL, DENISE MARIA. Recognition of breast cancer subtypes using FTIR hyperspectral data. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 310, p. 8-pg., 2024-01-29. (21/00633-0, 17/50332-0)

MALDONADO, EDISON PUIG; SAMAD, RICARDO ELGUL; ZUFFI, ARMANDO VALTER FELICIO; VIEIRA JR, NILSON DIAS. Simulation of self-modulated laser wakefield acceleration using few TW in downramp injection and ionization injection regimes. APPLIED OPTICS, v. 62, n. 12, p. 6-pg., 2023-04-20. (18/25961-7, 17/50332-0)

DEL VALLE, MATHEUS; STANCARI, KLEBER; AUGUSTO DE CASTRO, PEDRO ARTHUR; DOS SANTOS, MOISES OLIVEIRA; ZEZELL, DENISE MARIA; IEEE. Machine Learning methods for micro-FTIR imaging classification of human skin tumors. 2021 SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE (SBFOTON IOPC), v. N/A, p. 5-pg., 2021-01-01. (13/26113-6, 17/50332-0, 05/51689-2)

DE LIMA, CAROLINE S. A.; VARCA, JUSTINE P. R. O.; ALVES, VICTORIA M.; NOGUEIRA, KAMILA M.; CRUZ, CASSIA P. C.; RIAL-HERMIDA, M. ISABEL; KADLUBOWSKI, SLAWOMIR S.; VARCA, GUSTAVO H. C.; LUGAO, ADEMAR B.. Mucoadhesive Polymers and Their Applications in Drug Delivery Systems for the Treatment of Bladder Cancer. GELS, v. 8, n. 9, p. 25-pg., 2022-09-01. (17/50332-0)

SILVA, FELIPE D.; OLIVEIRA, JOAO E.; FREIRE, RENAN P.; SUZUKI, MIRIAM F.; SOARES, CARLOS R.; BARTOLINI, PAOLO. Expression of glycosylated human prolactin in HEK293 cells and related N-glycan composition analysis. AMB EXPRESS, v. 9, n. 1, AUG 29 2019. (15/26058-0, 17/50332-0)

SANTOS, JOSIEL F.; SILVA, CRYSTIAN WILLIAN C.; SILVA, BARBARA P. G.; BRITTO-COSTA, PEDRO H.; COSTA, CLEIDILANE S.; OTUBO, LARISSA; CARBONARI, ARTUR W.; CABRERA-PASCA, GABRIEL A.. Enhancing Cassava Starch Bioplastics with Vismia guianensis Alcoholic Extract: Characterization with Potential Applications. POLYMERS, v. 17, n. 3, p. 19-pg., 2025-02-01. (21/06712-9, 20/15230-5, 14/50279-4, 17/50332-0)

TAVARES, P. V. S.; DINIZ, R. E.; RODRIGUES JR, O.; CAMPOS, L. L.. Attenuation images of optical CT using Fricke xylenol orange gel for dose mapping in radiotherapy. Radiation Physics and Chemistry, v. 224, p. 8-pg., 2024-08-21. (17/50332-0)

VILLANI, D.; SAVI, M.; RODRIGUES JR, O.; POTIENS, M. P. A.; CAMPOS, L. L.. Computed tomography imaging analysis of a fused filament fabrication (FFF) 3D printed neck-thyroid phantom for multidisciplinary purposes. Radiation Physics and Chemistry, v. 224, p. 11-pg., 2024-08-21. (17/50332-0)

VINÍCIUS MAXIMIANO; ALANA CRISTINA MACHADO; RAQUEL MARIANNA LOPES; FERNANDA ELLEN MERCATELLI RABELO; STEPHANIE ASSIMAKOPOULOS GARÓFALO; DENISE MARIA ZEZELL; ANA CECILIA CORRÊA ARANHA; TAÍS SCARAMUCCI. Association of Nd:YAG laser and calcium-phosphate desensitizing pastes on dentin permeability and tubule occlusion. Journal of Applied Oral Science, v. 29, 2021-03-31. (17/50332-0, 17/02341-0, 17/24714-3)

VILLANI, D.; RODRIGUES, JR., O.; CAMPOS, L. L.. Dosimetric characterization of 3D printed phantoms at different infill percentages for diagnostic X-ray energy range. Radiation Physics and Chemistry, v. 172, JUL 2020. (17/50332-0)

LOPES, MNICA SCHAFFER; PEREIRA, DAISA LIMA; BRAINER DE OLIVEIRA MOTA, CLAUDIA CRISTINA; AMARAL, MARCELLO MAGRI; ZEZELL, DENISE MARIA; LEONIDAS GOMES, ANDERSON STEVENS. The lingual enamel morphology and bracket shear bond strength influenced by Nd:YAG laser and aluminum oxide sandblasting preconditioning. CLINICAL ORAL INVESTIGATIONS, v. 25, n. 3, JUN 2020. (17/50332-0, 05/51689-2)

KUZNETSOVA, MARIA; HASSE PALHARIM, PRISCILA; CLAUDINO, CAROLINE HELENA; ACUNA, JOSE JAVIER SAEZ; FRIN, KARINA P. M.; COLBEAU-JUSTIN, CHRISTOPHE; REMITA, HYND; SOUZA, JULIANA DOS SANTOS DE. Microwave-assisted synthesis of ZnO/BiNbO₄ heterojunctions for enhanced hydrogen production. NANOSCALE, v. 17, n. 26, p. 14-pg., 2025-06-20. (21/05958-4, 17/50332-0, 23/12948-0)

BOSCH-SANTOS, B.; NASCIMENTO, N. M.; SAIKI, M.; CORREA, E. L.; SALES, T. S. N.; PEREIRA, L. F. D.; CABRERA-PASCA, G. A.; SAXENA, R. N.; SCHELL, J.; CARBONARI, A. W.. Magnetic field at Ce impurities in La sites of La_0.5Ba_0.5MnO₃ double perovskites. AIP ADVANCES, v. 9, n. 3, p. 5-pg., 2019-03-01. (17/50332-0)

SANTOS, V, RENATA; CABRERA-PASCA, GABRIEL A.; COSTA, CLEIDILANE S.; BOSCH-SANTOS, BRIANNA; OTUBO, LARISSA; PEREIRA, LUCIANO F. D.; CORREA, BRUNO S.; EFFENBERGER, FERNANDO B.; BURIMOVA, ANASTASIA; FREITAS, RAFAEL S.; et al. Crystalline and magnetic properties of CoO nanoparticles locally investigated by using radioactive indium tracer. SCIENTIFIC REPORTS, v. 11, n. 1, OCT 25 2021. (19/15620-0, 17/50332-0, 15/16191-5)

GOMES NASCIMENTO, ANA CRISTINA; GALISTEO JUNIOR, ANDRES JIMENEZ; DA SILVA, GIOVANA DIAS; PEREIRA DE SOUZA ROCHA, LEONARDO WILANS; VIEIRA, DANIEL PEREZ. Effective methodology for maintaining Toxoplasma gondii in vitro using paramagnetic iron nanoparticles to support three-dimensional cell culture. BIOPHYSICAL REVIEWS, v. 13, n. 6, p. 1-pg., 2021-12-01. (17/50332-0)

SEBASTIAO, GLAUCIA I. A.; RANI-BORGES, BARBARA; DIPOLD, JESSICA; FREITAS, ANDERSON Z.; WETTER, NIKLAUS U.; ANDO, ROMULO A.; WALDMAN, WALTER R.. Forensic determination of adhesive vinyl microplastics in urban soils. Journal of Environmental Management, v. 373, p. 10-pg., 2024-12-06. (22/11983-4, 22/15586-0, 22/12104-4, 17/50332-0, 18/19240-5)

PAZ LIMA, MAYELLE MARIA; DO NASCIMENTO, PAMELA FERREIRA; GOMES NASCIMENTO, ANA CRISTINA; VIEIRA, DANIEL PEREZ. A simple and quick method to generate in vitro tridimensional tumor bodies from a human breast adenocarcinoma (MCF7) using magnetic aggregation technique. BIOPHYSICAL REVIEWS, v. 13, n. 6, p. 1-pg., 2021-12-01. (17/50332-0)

ARAUJO, ERIKA MICHELE DOS SANTOS; VIDAL, CRISTINA DE MATTOS PIMENTA; ZHU, MIN; BANAS, JEFFREY A.; FREITAS, ANDERSON ZANARDI DE; WETTER, NIKLAUS URSUS; MATOS, ADRIANA BONA. Comparison of biofilm models for producing artificial active white spot lesions. Journal of Applied Oral Science, v. 32, p. 10-pg., 2024-01-01. (18/19240-5, 17/50332-0)

DEL-VALLE, MATHEUS; SANTOS, MOISES OLIVEIRA DOS; SANTOS, SOFIA NASCIMENTO DOS; CASTRO, PEDRO ARTHUR AUGUSTO DE; BERNARDES, EMERSON SOARES; ZEZELL, DENISE MARIA. The impact of scan number and its preprocessing in micro-FTIR imaging when applying machine learning for breast cancer subtypes classification. VIBRATIONAL SPECTROSCOPY, v. 117, NOV 2021. (17/50332-0)

CORREA, E. L.; BOSCH-SANTOS, B.; SAXENA, R. N.; CABRERA-PASCA, G. A.; CARBONARI, A. W.. Effects of an external magnetic field on the hyperfine parameters in RE2O3 (RE = Gd, Er) nanoparticles measured by perturbed angular correlation spectroscopy. AIP ADVANCES, v. 10, n. 1, JAN 2020. (17/50332-0)

DE CARVALHO, L. R.; VIEIRA, D. P.. Evaluation of genotoxic potential of peptides used in nuclear medicine (PSMA -617 and -11, and ubiquicidine 29-41) using a flow-cytometric, semi-automated analysis of micronuclei frequency in cell cultures. TOXICOLOGY REPORTS, v. 7, p. 304-316, 2020. (17/50332-0)

DARUICH DE SOUZA, CARLA; BUENO BARBEZAN, ANGELICA; ARCOS ROSERO, WILMMER ALEXANDER; NASCIMENTO DOS SANTOS, SOFIA; VERGACAS DE SOUSA CARVALHO, DIEGO; ZEITUNI, CARLOS ALBERTO; SOARES BERNARDES, EMERSON; PEREZ VIEIRA, DANIEL; SPENCER, PATRICK JACK; SIMOES RIBEIRO, MARTHA; et al. ynthesis, In Vitro Testing, and Biodistribution of Surfactant-Free Radioactive Nanoparticles for Cancer Treatmen. NANOMATERIALS, v. 12, n. 2, JAN 2022. (18/18526-2, 17/50332-0)

BORDON, CAMILA DIAS DA SILVA; DIPOLD, JESSICA; WETTER, NIKLAUS U. U.; DE ROSSI, WAGNER; FREITAS, ANDERSON Z. Z.; KASSAB, LUCIANA R. P.. Effect of Silver Nanoparticles on the Optical Properties of Double Line Waveguides Written by fs Laser in Nd3+-Doped GeO2-PbO Glasses. NANOMATERIALS, v. 13, n. 4, p. 13-pg., 2023-02-01. (18/19240-5, 13/26113-6, 17/50332-0, 16/02326-9, 17/10765-5, 19/06334-4)

CARAMEL-JUVINO, AMANDA; FAROOQ, SAJID; ROMANO, MARIANA; ZEZELL, DENISE MARIA; IEEE. Identification of enamel demineralization using high performance convolutional neural network. 2022 SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE (SBFOTON IOPC), v. N/A, p. 3-pg., 2022-01-01. (17/50332-0)

FAROOQ, SAJID; CARAMEL-JUVINO, AMANDA; DEL-VALLE, MATHEUS; SANTOS, SOFIA; BERNANDES, EMERSON SOARES; ZEZELL, DENISE MARIA; IEEE. Superior Machine Learning Method for breast cancer cell lines identification. 2022 SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE (SBFOTON IOPC), v. N/A, p. 3-pg., 2022-01-01. (17/50332-0)

ZUFFI, ARMANDO V. F.; TABACOW, FABIO B. D.; VIEIRA, NILSON D.; SAMAD, RICARDO E.; IEEE. Ultrafast laser micromachining of submillimetric de Laval nozzles in alumina for laser electron acceleration. 2022 SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE (SBFOTON IOPC), v. N/A, p. 5-pg., 2022-01-01. (18/25961-7, 17/50332-0)

ZUFFI, ARMANDO VALTER FELICIO; DOS SANTOS, JHONATHA RICARDO; MALDONADO, EDISON PUIG; VIEIRA JR, NILSON DIAS; SAMAD, RICARDO ELGUL. Femtosecond laser-plasma dynamics study by a time-resolved Mach-Zehnder-like interferometer. APPLIED OPTICS, v. 62, n. 8, p. 7-pg., 2023-03-10. (17/50332-0, 21/13737-8)

FAROOQ, SAJID; DEL-VALLE, MATHEUS; DOS SANTOS, MOISES OLIVEIRA; DOS SANTOS, SOFIA NASCIMENTO; BERNARDES, EMERSON SOARES; ZEZELL, DENISE MARIA. Rapid identification of breast cancer subtypes using micro-FTIR and machine learning methods. APPLIED OPTICS, v. 62, n. 8, p. 8-pg., 2023-03-10. (21/00633-0, 17/50332-0)

CASTRO, PEDRO A. A.; LIMA, CASSIO A.; MORAIS, MYCHEL R. P. T.; ZORN, TELMA M. T.; ZEZELL, DENISE M.. Monitoring the Progress and Healing Status of Burn Wounds Using Infrared Spectroscopy. Applied Spectroscopy, v. 74, n. 7, MAY 2020. (13/26113-6, 17/50332-0, 05/51689-2)

MALDONADO, EDISON PUIG; SAMAD, RICARDO ELGUL; ZUFFI, ARMANDO VALTER FELICIO; DOS SANTOS, JHONATHA RICARDO; VIEIRA JUNIOR, NILSON DIAS. Impact of He+N₂ concentration on self-modulated laser wakefield acceleration driven by pulses of a few TW. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, v. 40, n. 4, p. 7-pg., 2023-04-01. (18/25961-7, 17/50332-0, 21/13737-8)

BURIMOVA, ANASTASIA; CARBONARI, ARTUR WILSON; DE LIMA, NICOLE PEREIRA; MIRANDA FILHO, ARNALDO ALVES; DOS SANTOS SOUZA, ALEXANDRE PINHO; NASCIMENTO SALES, TATIANE DA SILVA; FERREIRA, WANDERSON LOBATO; DIAS PEREIRA, LUCIANO FABRICIO; CORREA, BRUNO SANTOS; SAXENA, RAJENDRA NARAIN. Local Crystalline Structure of Doped Semiconductor Oxides Characterized by Perturbed Angular Correlations: Experimental and Theoretical Insights. CRYSTALS, v. 12, n. 9, p. 15-pg., 2022-09-01. (18/18657-0, 19/15620-0, 17/50332-0)

DOS SANTOS, JHONATHA RICARDO; BUENO, PATRICIA; JAKUTIS, JONAS; VICTOR, ALESSANDRO R.; BARRETA, LUIZ F. N.; SBAMPATO, MARIA ESTHER; NERI, JOST W.; SILVEIRA, CARLOS A. B.; RODRIGUES, NICOLAU A. S.; DESTRO, MARCELO GERALDO. Dysprosium optogalvanic spectroscopy in a hollow cathode lamp. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, v. 40, n. 5, p. 7-pg., 2023-05-01. (21/13737-8, 17/50332-0)

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