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Multi-user equipment approved in grant 2018/01550-8: electro-spray equipment to obtain bioactive compounds into nanostructures

Grant number: 18/13408-1
Support type:Multi-user Equipment Program
Duration: August 01, 2018 - July 31, 2025
Field of knowledge:Agronomical Sciences - Food Science and Technology
Principal Investigator:Anna Rafaela Cavalcante Braga
Grantee:Anna Rafaela Cavalcante Braga
Home Institution: Instituto de Saúde e Sociedade (ISS). Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Santos , SP, Brazil
Associated research grant:18/01550-8 - Nanoestructures containing anthocyanins extracted from juçara pulp (Euterpe edulis Mart.): interaction with lactic acid bacteria and bioavailability, AP.R
EMU web page: Página do Equipamento Multiusuário não informada
Use scheduling: E-mail de agendamento não informado


The beneficial health properties had led to consumers growing interest in the consumption of products containing bioactive compounds. Among the more than 20 thousand species of plants present in the Atlantic Forest the jussara fruit (Euterpe edulis Mart.) stands out for its contents of phenolic and other bioactive compounds present in its composition. The biological action of phenolic compounds, particularly anthocyanins, has been demonstrated in in vitro experiments; however, this activity is not always reproduced in vivo, since it is dependent on factors such as absorption, metabolism, tissue distribution, composition intestinal microbiota and excretion. Intestinal microbiota has been targeted by many studies since their importance in all aspects of human health; however, the difficulty of improving the general population microbiota using fermentative processes to pre-digest biocompounds before its consumption is an interesting alternative to a wide the range of benefits of bioactive compounds. Instability against environmental stress and low bioaccessibility and bioavailability are the main limitations of anthocyanins industrial application, in this perspective, nanoencapsulated phenolic compounds can solve their restrictions. The objective of this project is to evaluate the production of nanostructures containing fermented anthocyanins extracts from jussara and to compare them, in terms of bioaccessibility, bioavailability with to nanocapsules of microorganisms added with fruit extract. (AU)