Manufacture of disposable electrochemical devices composed of hollow carbon nanospheres and carbon nanowires decorated with silver nanoparticles for the quantification of endocrine disruptors in supply water samples

• Grant number: 19/01777-5
• Support Opportunities: Regular Research Grants
• Start date: May 01, 2019
• End date: April 30, 2021
• Field of knowledge: Engineering - Sanitary Engineering - Water Supply and Wastewater Treatment
• Principal Investigator: Sergio Antonio Spinola Machado
• Grantee: Sergio Antonio Spinola Machado
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Associated researchers: Paulo Augusto Raymundo Pereira
• Associated scholarship(s): 19/11080-1 - Development of disposable electrochemical devices composed of hollow carbon nanospheres and carbon nanowires decorated with silver nanoparticles for the quantification of endocrine disruptors in supply water samples, BP.TT

Abstract

One of the major threats to the environment and, consequently, to human health is the release, in the environment, of the so-called endocrine disrupters. These are organic molecules, synthetic or not, which, because of their chemical properties, have the potential to interfere with the functioning of the endocrine system, that is, the functioning of the glands of the human organism. Several classes of organic molecules have this characteristic such as pesticides, some drugs, hormones and their metabolites, molecules such as bisphenol-A, etc. All are classified as emerging pollutants due to the drastic increase in their daily use with consequent waste disposal in the environment where there is no natural mechanism of degradation for such molecules. Thus, the toxic characteristics of this class of pollutants require continuous monitoring and specific regulation of government agencies, with the establishment of the maximum residues amount acceptable in food, water, etc. However, this regulation does not exist and monitoring, in water supply, is not done. This research project proposes the development of a fast, low cost and miniaturizable electrochemical analytical method for the in situ and real time detection of hormones in water supply. This method will be based on screen printed carbon electrodes modified with hollow carbon nanospheres decorated with silver nanoparticles for use in the quantification of hormones without the need for a conventional electrochemical cell. The electrochemical measurements will be made in an easily miniaturized equipment and compared, through an adequate statistical methodology, with those obtained by the standard method, that is, by high performance liquid chromatography. (AU)

Scientific publications

(17)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BRAZACA, LAIS CANNIATTI; IMAMURA, AMANDA HIKARI; GOMES, NATHALIA OEZAU; ALMEIDA, MARIANA BORTHOLAZZI; SCHEIDT, DESIREE TAMARA; RAYMUNDO-PEREIRA, PAULO A.; OLIVEIRA JR, OSVALDO N.; JANEGITZ, BRUNO CAMPOS; SPINOLA MACHADO, SERGIO ANTONIO; CARRILHO, EMANUEL. Electrochemical immunosensors using electrodeposited gold nanostructures for detecting the S proteins from SARS-CoV and SARS-CoV-2. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, v. 414, n. 18, p. 11-pg., 2022-02-15. (20/09587-8, 17/21097-3, 19/01777-5, 17/05362-9, 18/22214-6, 16/01919-6, 18/19750-3)

RAYMUNDO-PEREIRA, PAULO A.; GOMES, NATHALIA O.; SHIMIZU, FLAVIO M.; MACHADO, SERGIO A. S.; OLIVEIRA, JR., OSVALDO N.. Selective and sensitive multiplexed detection of pesticides in food samples using wearable, flexible glove-embedded non-enzymatic sensors. CHEMICAL ENGINEERING JOURNAL, v. 408, MAR 15 2021. (16/01919-6, 13/14262-7, 18/22214-6, 19/01777-5)

RAYMUNDO-PEREIRA, PAULO A.; GOMES, NATHALIA O.; MACHADO, SERGIO A. S.; OLIVEIRA, JR., OSVALDO N.. Simultaneous, ultrasensitive detection of hydroquinone, paracetamol and estradiol for quality control of tap water with a simple electrochemical method. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 848, SEP 1 2019. (16/12759-0, 13/14262-7, 16/01919-6, 19/01777-5)

NETO, JOSE L. BOTT; MARTINS, THIAGO S.; MACHADO, SERGIO A. S.; OLIVEIRA JR, OSVALDO N.. Enhanced photocatalysis on graphitic carbon nitride sensitized with gold nanoparticles for photoelectrochemical immunosensors. Applied Surface Science, v. 606, p. 6-pg., 2022-12-30. (19/13514-9, 18/22214-6, 19/01777-5)

MARTONI, LUCAS V. L.; GOMES, NATHALIA O.; PRADO, THIAGO M.; CALEGARO, MARCELO L.; OLIVEIRA JR, OSVALDO N.; MACHADO, SERGIO A. S.; RAYMUNDO-PEREIRA, PAULO A.. Carbon spherical shells in a flexible photoelectrochemical sensor to determine hydroquinone in tap water. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 10, n. 3, p. 9-pg., 2022-04-01. (20/09587-8, 19/01777-5, 16/01919-6, 18/22214-6)

MARTINS, THIAGO S.; BOTT-NETO, JOSE L.; OLIVEIRA, JR., OSVALDO N.; MACHADO, SERGIO A. S.. A sandwich-type electrochemical immunosensor based on Au-rGO composite for CA15-3 tumor marker detection. Microchimica Acta, v. 189, n. 1, JAN 2022. (18/22214-6, 19/13514-9, 19/01777-5)

GOMES, NATHALIA O.; MENDONCA, CAMILA D.; MACHADO, SERGIO A. S.; OLIVEIRA, JR., OSVALDO N.; RAYMUNDO-PEREIRA, PAULO A.. lexible and integrated dual carbon sensor for multiplexed detection of nonylphenol and paroxetine in tap water sample. Microchimica Acta, v. 188, n. 10, OCT 2021. (19/01777-5, 18/22214-6, 16/06139-9)

MARTINS, THIAGO S.; BOTT-NETO, JOSE L.; OLIVEIRA, JR., OSVALDO N.; MACHADO, SERGIO A. S.. Paper-based electrochemical sensors with reduced graphene nanoribbons for simultaneous detection of sulfamethoxazole and trimethoprim in water samples. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 882, FEB 1 2021. (19/13514-9, 18/22214-6, 19/01777-5)

MARTINS, THIAGO S.; MACHADO, SERGIO A. S.; OLIVEIRA JR, OSVALDO N.; BOTT-NETO, JOSE L.. Optimized paper-based electrochemical sensors treated in acidic media to detect carbendazim on the skin of apple and cabbage. Food Chemistry, v. 410, p. 7-pg., 2023-01-13. (19/13514-9, 22/03758-0, 18/22214-6, 19/01777-5)

RAYMUNDO-PEREIRA, PAULO A.; GOMES, NATHALIA O.; MACHADO, SERGIO A. S.; OLIVEIRA JR, OSVALDO N.. Wearable glove-embedded sensors for therapeutic drug monitoring in sweat for personalized medicine. CHEMICAL ENGINEERING JOURNAL, v. 435, p. 9-pg., 2022-05-01. (19/01777-5, 20/09587-8, 09/54216-9, 18/22214-6, 16/01919-6)

MARTINS, THIAGO S.; BOTT-NETO, JOSE L.; MACHADO, SERGIO A. S.; OLIVEIRA, OSVALDO N.. Label-Free Electrochemical Immunosensor Made with Tree-like Gold Dendrites for Monitoring 25-Hydroxyvitamin D3 Metabolite. ACS APPLIED MATERIALS & INTERFACES, v. 14, n. 27, p. 8-pg., 2022-07-13. (19/13514-9, 18/22214-6, 19/01777-5)

BONDANCIA, THALITA J.; SOARES, ANDREY COATRINI; POPOLIN-NETO, MARIO; GOMES, NATHALIA O.; RAYMUNDO-PEREIRA, PAULO A.; BARUD, HERNANE S.; MACHADO, SERGIO A. S.; RIBEIRO, SIDNEY J. L.; MELENDEZ, MATIAS E.; CARVALHO, ANDRE L.; et al. Low-cost bacterial nanocellulose-based interdigitated biosensor to detect the p53 cancer biomarker. BIOMATERIALS ADVANCES, v. 134, p. 7-pg., 2022-03-01. (20/09587-8, 19/01777-5, 18/18953-8, 18/22214-6, 16/01919-6)

PASCHOALIN, RAFAELLA T.; GOMES, NATHALIA O.; ALMEIDA, GABRIELA F.; BILATTO, STANLEY; FARINAS, CRISTIANE S.; MACHADO, SERGIO A. S.; MATTOSO, LUIZ H. C.; OLIVEIRA JR, OSVALDO N.; RAYMUNDO-PEREIRA, PAULO A.. Wearable sensors made with solution-blow spinning poly(lactic acid) for non-enzymatic pesticide detection in agriculture and food safety. BIOSENSORS & BIOELECTRONICS, v. 199, p. 7-pg., 2022-03-01. (20/09587-8, 16/10636-8, 19/01777-5, 18/22214-6, 18/10899-4, 16/01919-6, 17/18725-2)

GOMES, NATHALIA O.; PASCHOALIN, RAFAELLA T.; BILATTO, STANLEY; SORIGOTTI, AMANDA R.; FARINAS, CRISTIANE S.; MATTOSO, LUIZ HENRIQUE C.; MACHADO, SERGIO A. S.; OLIVEIRA JR, OSVALDO N.; RAYMUNDO-PEREIRA, PAULO A.. Flexible, Bifunctional Sensing Platform Made with Biodegradable Mats for Detecting Glucose in Urine. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 11, n. 6, p. 10-pg., 2023-02-13. (19/01777-5, 20/09587-8, 16/10636-8, 17/18725-2, 18/22214-6, 13/07296-2, 18/10899-4, 22/02164-0, 16/01919-6)

MARTINS, THIAGO S.; BOTT-NETO, JOSE L.; MACHADO, SERGIO A. S.; OLIVEIRA JR, OSVALDO N.. Label-Free Electrochemical Immunosensor Made with Tree-like Gold Dendrites for Monitoring 25-Hydroxyvitamin D3 Metabolite. ACS APPLIED MATERIALS & INTERFACES, v. N/A, p. 8-pg., 2022-07-01. (19/01777-5, 19/13514-9, 18/22214-6)

BOTT-NETO, JOSE L.; MARTINS, THIAGO S.; BUSCAGLIA, LORENZO A.; MACHADO, SERGIO A. S.; OLIVEIRA, OSVALDO N. JR JR. Photocatalysis of TiO2 Sensitized with Graphitic Carbon Nitride and Electrodeposited Aryl Diazonium on Screen-Printed Electrodes to Detect Prostate Specific Antigen under Visible Light. ACS APPLIED MATERIALS & INTERFACES, v. 14, n. 19, p. 8-pg., 2022-05-18. (19/13514-9, 19/00101-8, 18/22214-6, 19/01777-5)

GOMES, NATHALIA O.; TEIXEIRA, SAMIRIS COCCO; CALEGARO, MARCELO L.; MACHADO, SERGIO A. S.; FERREIRA SOARES, NILDA DE FATIMA; DE OLIVEIRA, TAILA VELOSO; RAYMUNDO-PEREIRA, PAULO A.. Flexible and sustainable printed sensor strips for on-site, fast decentralized self-testing of urinary biomarkers integrated with a portable wireless analyzer. CHEMICAL ENGINEERING JOURNAL, v. 472, p. 10-pg., 2023-09-15. (23/07686-7, 19/01777-5, 22/02164-0, 23/00850-6, 16/01919-6, 20/09587-8)