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R&D&I in radiation metrology in the health area

Grant number: 18/05982-0
Support type:Research Projects - Thematic Grants
Duration: October 01, 2019 - September 30, 2024
Field of knowledge:Engineering - Nuclear Engineering - Applications of Radioisotopes
Principal researcher:Linda Viola Ehlin Caldas
Grantee:Linda Viola Ehlin Caldas
Home Institution: Instituto de Pesquisas Energéticas e Nucleares (IPEN). Secretaria de Desenvolvimento Econômico (São Paulo - Estado). São Paulo , SP, Brazil
Pesquisadores principais:
Elisabeth Mateus Yoshimura ; Leticia Lucente Campos Rodrigues
Assoc. researchers:Alessandra Tomal ; Alessio Mangiarotti ; Carmen Cecília Bueno ; Denise Yanikian Nersissian ; Emico Okuno ; Josemary Angélica Corrêa Gonçalves ; Laura Furnari ; Maria da Penha Albuquerque Potiens ; Nancy Kuniko Umisedo ; Neilo Marcos Trindade ; Orlando Rodrigues Júnior ; Patrícia Nicolucci ; Paulo Roberto Costa
Associated grant(s):22/03751-6 - 9th International Conference on Optical, Optoelectronic and Photonic Materials and Applications & 14th Europhysical Conference on Defects in Insulating Material, AR.EXT
Associated scholarship(s):22/06695-0 - Development of an EPR protocol for dosimetric characterization of co-doped rare-earth yttria based micro ceramics, BP.TT
21/12758-1 - Development and characterization of an optically stimulated luminescent detector based on natural Brazilian alexandrite, BP.MS
21/14688-0 - Development and validation of materials radiologically equivalent to human tissues for ionizing radiation dosimetry and quality control, BP.PD
20/06268-9 - Optimization of the production techniques and investigation of the viability of the MgB4O7:Ce,Li as a dosimetric material, BP.PD
20/04577-4 - Validation of human tissue-equivalent materials for ionizing radiation dosimetric and quality control purposes applied to radiography and computed tomography techniques, BP.IC


The applications of ionizing radiations in different areas, such as health, industry, environment and agriculture, have a direct effect on the life quality of the population. Therefore, the improvement of methods and techniques, and the development of instruments and systems for the radiation measurement, are essential for that their use is beneficial, effective and, at the same time, to comply with all safety requirements, avoiding the adverse radiation risks. This project is based on research, development and innovation in metrology of ionizing radiations with applications in the areas of radiotherapy, diagnostic radiology and nuclear medicine, and sterilization of medical materials and instruments. The aim is to form a metrological basis for the calibration of detectors with alpha, beta, gamma and X radiations, for new dosimetric systems and methodologies in radiation metrology, using luminescent and other techniques, generating national and international technical-scientific impact and contributing for the safe use of ionizing radiations. The research methodology will consist on the development and implementation of: dosimetric materials and systems, phantoms for radiotherapy and diagnostic radiology, ionizing chambers, radiation detectors and new methodologies (for solid state detectors and polymeric gels), interacting with national and international groups of excellence in the area. Another important goal will be the training of personnel in radiation metrology applied to medicine. The originality and relevance of the proposal consist in the development, improvement and establishment of new materials, instruments and techniques useful for radiation metrology and dosimetry, including also computational simulation techniques. (AU)

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Scientific publications (13)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
UMISEDO, NANCY K.; OKUNO, EMICO; CANCIO, FRANCISCO; YOSHIMURA, ELISABETH M.; KUNZEL, ROSELI. Development of a mechanically resistant fluorite-based pellet to be used in personal dosimetry. Radiation Measurements, v. 134, . (18/05982-0)
TRINDADE, N. M.; SILVA, E. P.; NUNES, M. C. S.; MUNOZ, J. M.; SANTOS, J. C. A.; YOSHIMURA, E. M.; SILVA, R. S.. Synthesis and thermoluminescence properties of MgAl2O4:Ca laser-sintered ceramics. Optical Materials, v. 108, . (18/05982-0, 19/05915-3, 18/16894-4, 19/22375-2)
MASSERA, RODRIGO T.; THOMSON, ROWAN M.; TOMAL, ALESSANDRA. Technical note: MC-GPU breast dosimetry validations with other Monte Carlo codes and phase space file implementation. Medical Physics, v. 49, n. 1, . (18/05982-0, 15/21873-8, 16/15366-9)
DE OLIVEIRA, LUCAS N.; DO NASCIMENTO, ERIBERTO O.; CALDAS, LINDA V. E.. A new natural detector for irradiations with blue LED light source in photodynamic therapy measurements via UV-Vis spectroscopy. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, v. 20, n. 11, . (18/05982-0)
MUNOZ, J. M.; LIMA, L. S.; YOSHIMURA, E. M.; JACOBSOHN, L. G.; TRINDADE, N. M.. OSL response of alpha-Al2O3:C, Mg exposed to beta and UVC radiation: A comparative investigation. Journal of Luminescence, v. 236, . (19/05915-3, 19/22375-2, 18/05982-0)
TRINDADE, N. M.; CRUZ, M. R.; YOSHIMURA, E. M.. Correlation between thermoluminescence and optically stimulated luminescence responses of natural alexandrite. Applied Radiation and Isotopes, v. 166, . (19/05915-3, 18/05982-0)
DE OLIVEIRA, LUCAS NONATO; DO NASCIMENTO, ERIBERTO OLIVEIRA; CALDAS, LINDA V. E.. New Fricke Xylenol Liquid detector doped with methylene blue (FXL-mblue) irradiated with red LED light. Journal of Luminescence, v. 230, . (18/05982-0)
DE OLIVEIRA, LUCAS NONATO; DO NASCIMENTO, ERIBERTO OLIVEIRA; MORAIS JUNIOR, PEDRO DE AQUINO; ANTONIO, PATRICIA DE LARA; CALDAS, LINDA V. E.. Evaluation of high-linearity bone radiation detectors exposed to gamma-rays via FTIR measurements. Applied Radiation and Isotopes, v. 170, . (18/05982-0)
BATISTA, WILSON OTTO; SOARES, MARIA ROSANGELA; GURJAO RIOS, JACQUELINE MACHADO; DOS SANTOS SOUZA, ANTONIO CARLOS; PINHEIRO, ISABELLE MATOS; JAVIER VEGA RAMIREZ, JOSE LUIS; CALDAS, LINDA V. E.. Assessment of scattered radiation from hand-held dental x-ray equipment using the Monte Carlo method. JOURNAL OF RADIOLOGICAL PROTECTION, v. 41, n. 4, p. 654-668, . (18/05982-0)
CASTRO, MAYSA C.; SILVA, NATALIA F.; SANTOS, WILLIAM S.; CALDAS, LINDA V. E.. Performance comparison of an extrapolation chamber in computed tomography standard beams of two laboratories. Radiation Physics and Chemistry, v. 189, . (18/05982-0)
COSTA, PAULO R.; NERSISSIAN, DENISE Y.; UMISEDO, NANCY K.; GONZALES, ALEJANDRO H. L.; FERNANDEZ-VAREA, JOSE M.. A comprehensive Monte Carlo study of CT dose metrics proposed by the AAPM Reports 111 and 200. Medical Physics, v. 49, n. 1, . (10/12237-7, 18/05982-0)
NUNES, M. C. S.; LIMA, L. S.; YOSHIMURA, E. M.; FRANCA, L. V. S.; BAFFA, O.; JACOBSOHN, L. G.; MALTHEZ, A. L. M. C.; KUNZEL, R.; TRINDADE, N. M.. Characterization of the optically stimulated luminescence (OSL) response of beta-irradiated alexandrite-polymer composites. Journal of Luminescence, v. 226, . (19/05915-3, 18/05982-0, 18/16894-4)
DO NASCIMENTO, ERIBERTO OLIVEIRA; PIRES BECATTI, MATHEUS JOSE; CALDAS, LINDA V. E.; DE OLIVEIRA, LUCAS NONATO. Design of Experiments (DoE) method for solar protective films via UV-Vis and NIR spectrophotometry measurements. Journal of Luminescence, v. 242, . (18/05982-0)

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