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Study of adhesion and proliferation of stem cells in capacitive electrical stimuli over scaffolds in 2D and 3D made by electrospinning and Solution Blow Spinning

Grant number: 19/15781-4
Support Opportunities:Regular Research Grants
Duration: December 01, 2019 - November 30, 2022
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
Convênio/Acordo: University of Manchester
Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
Principal Investigator:Susana Inés Córdoba de Torresi
Grantee:Susana Inés Córdoba de Torresi
Principal researcher abroad: Sarah Cartmell
Institution abroad: University of Manchester, England
Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated researchers: Jonathan James Blaker ; Roberto Manuel Torresi
Associated research grant:18/13492-2 - Synthetic and natural scaffolds applied to regenerative medicine, AP.TEM


The aim of this project is to swap knowledge and expertise in scaffolds with 2D and 3D structures built up by electrospinning and solution blow spinning using PEDOT-co-PDLLA in the molar proportion PEDOT: PDLLA 1:50, 1:25 and 1:5. It is expected material maintain their features associated with electroactive, biocompatible and biodegradable properties. The two kinds of scaffold could have macro-/microporous bers with 3D interconnected pores, which is ideal to apply in stem cells at capacitive electrical stimuli. Our objective is to build a collaboration between the two partners to propose a protocol for preparing such surfaces without involving costlier 2D and 3D build techniques. (AU)

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