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Translational studies of head and neck cancer in South America and Europe

Grant number: 18/26297-3
Support type:Research Projects - Thematic Grants
Duration: December 01, 2019 - November 30, 2023
Field of knowledge:Health Sciences - Collective Health - Epidemiology
Cooperation agreement: European Commission (Horizon 2020)
Principal researcher:Maria Paula Curado
Grantee:Maria Paula Curado
Principal researcher abroad: Paul Brennan
Institution abroad: World Health Organization, Swiss (WHO), Switzerland
Home Institution: A C Camargo Cancer Center. Fundação Antonio Prudente (FAP). São Paulo , SP, Brazil
Pesquisadores principais:
Luiz Paulo Kowalski
Assoc. researchers: Gisele Aparecida Fernandes ; Stela Verzinhasse Peres ; Vinicius Fernando Calsavara
Associated scholarship(s):20/09088-1 - Translational studies of head and neck cancer in South America and Europe (headspace) / H2020, BP.JC
20/08805-1 - Translational studies of head and neck cancer in South America and Europe, BP.PD


Worldwide, more than 550,000 new cases of head and neck cancer (HNC) occur each year, resulting in approximately 300,000 deaths annually. It is the 6th most common cancer in both Europe and South America. A major reason for the high mortality rate for this cancer is the late stage of diagnosis for many patients. Accurate assessment of the prognosis of HNC cases also allows for appropriate treatment decisions. HEADSpAcE will bring together a consortium of 15 partners with a long and successful record of collaboration in HNC. The impact of HEADSpAcE will be to understand reasons for late diagnosis and reduce the proportion of HNC that are diagnosed at a very late stage. It will identify the most appropriate way to diagnosis cancer caused by human papilloma virus (HPV), and also provide genomic evidence of strong predictors of prognosis that will have the potential to improve care and reduce treatment related morbidity. Within this project, we will develop guidelines for implementation into clinical care. All these activities will be disseminated through communications tools achieving researchers, young researchers and pos graduate students, for patient and family will be available through HEADSpAce website. (AU)

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