Influence of body weight or composition on clinical, biomechanical and muscular condition of individuals with patellofemoral pain: a prospective study

• Grant number: 20/14715-5
• Support Opportunities: Regular Research Grants
• Start date: July 01, 2022
• End date: June 30, 2024
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Fábio Mícolis de Azevedo
• Grantee: Fábio Mícolis de Azevedo
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil
• Associated researchers: David Matthew Bazett-Jones ; Fernando Henrique Magalhães ; Luis Mochizuki ; Rômulo Araújo Fernandes ; Ronaldo Valdir Briani
• Associated scholarship(s): 23/05014-1 - Scientific technical training for biomechanical analysis of human movement., BP.TT; 23/07004-3 - Scientific technical training for biomechanical analysis of human movement., BP.TT; 22/10069-7 - Influence of body weight on clinical, mechanical and muscular condition decomposition of patellofemoral biocomposition: A prospective study., BP.TT; 22/10236-0 - Influence of weight or body composition on the clinical, biomechanical and muscular condition of individuals with patellofemoral pain: A prospective study, BP.TT

Abstract

The increase in body weight is a public health problem associated with several musculoskeletal disorders. Recently, a systematic review reported that individuals with patellofemoral pain (PFP) have a higher body mass index (BMI) compared to asymptomatic individuals. Recent studies from our group have also reported that women with PFP have higher percentage of body fat and less muscle mass compared to controls; and that a higher percentage of body fat and a lower percentage of lean mass are associated with worse functional capacity and lower torque of the knee and hip muscles in individuals with PFP. The increase in body weight is commonly associated with a decrease in the physical activity level and can influence several factors that are altered in individuals with PFP, such as pain, function, psychological factors, quality of life, muscle torque, and biomechanical parameters. However, no longitudinal studies have been performed to investigate the influence of body weight, body composition, and physical activity level on the long-term clinical, biomechanical, and muscular condition of men and women with PFP. Therefore, this project aims to investigate the influence of body weight, body composition and physical activity level on pain, function, quality of life, psychological factors, objective function, muscle torque of the knee and hip muscles, and patellofemoral stress in individuals with PFP over a 3-year period. Men and women with PFP and aged between 18 and 35 years will be recruited to participate in this study. Self-reported data (ie, pain, function, quality of life, kinesiophobia, pain catastrophism, level of physical activity), anthropometric measures (ie, body weight, height, skinfolds), body composition, performance in functional tests such as the single leg hop test, maximum torque of the knee extensors and flexors and hip abductors, and biomechanical data will be obtained, with the latter being used to calculate patellofemoral stress. Statistical tests will be used to compare the variables of interest after 3 years (baseline x follow up). Linear regressions will be performed to investigate how changes in body weight, body composition and physical activity level explain changes in the clinical, biomechanical and muscle capacity of men and women with PFP. For those individuals who had no clinically important change in body weight (less than ±7% change in body weight), linear regressions will be calculated to investigate how much body weight and body composition after 3 years explain clinical, biomechanical, and capacity muscle of men and women with PFP. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BOTTA, ANA FLAVIA BALOTARI; WAITEMAN, MARINA CABRAL; DUCATTI, MATHEUS HENRIQUE MAIOLINI; GARCIA, CARMEN LUCIA GOMES; FARINELLI, LUCCA ANDRE LIPORONI BEGO; BAZETT-JONES, DAVID MATTHEW; BRIANI, RONALDO VALDIR; DE AZEVEDO, FABIO MICOLIS. Patellofemoral pain over time: Protocol for a prospective, longitudinal study investigating physical and non-physical features. FRONTIERS IN SPORTS AND ACTIVE LIVING, v. 4, p. 11-pg., 2023-01-11. (20/12703-0, 22/10236-0, 22/10069-7, 20/14715-5, 20/12257-0)