Biology of Bacteria and Bacteriophages Research Center

• Grant number: 21/10577-0
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• Duration: May 01, 2023 - April 30, 2028
• Field of knowledge: Biological Sciences - Biochemistry - Biochemistry of Microorganisms
• Principal Investigator: Shaker Chuck Farah
• Grantee: Shaker Chuck Farah
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Pesquisadores principais: Aline Maria da Silva ; Beny Spira ; Cristiane Rodrigues Guzzo Carvalho ; Henrique Ferreira ; Marcelo Brocchi ; Marcio Vinicius Bertacine Dias ; Marilis Do Valle Marques ; Regina Lúcia Baldini ; Roberto Kopke Salinas ; Rodrigo da Silva Galhardo ; Sandro Roberto Marana
• Associated researchers: Cristiane Rodrigues Guzzo Carvalho ; Cristina Elisa Alvarez Martinez ; Frederico José Gueiros Filho ; Germán Gustavo Sgro ; João Carlos Setubal ; José Freire da Silva Neto ; Leonardo Talachia Rosa ; Marcio Vinicius Bertacine Dias ; Marco Aurélio Takita ; Rita de Cássia Café Ferreira ; Robson Francisco de Souza ; Rodrigo da Silva Galhardo
• Associated grant(s): 23/12239-0 - Multi-user equipment approved in grant 2021/10577-0: PEAQ-ITC (Isothermal Calorimeter), AP.EMU
• Associated scholarship(s): 23/13291-5 - Determining the intrinsic levels of ppGpp across a species and its influence on growth rate and tolerance to antibiotics, BP.DD; 23/05679-3 - Characterization of xac4136 gene as a putative Type VI Secretion System effector in Xanthomonas citri, BP.MS; 23/12063-9 - Dissemination of concepts in microbiology: Impact assessment on basic education., BP.IC; + associated scholarships 23/13177-8 - Development and implementation of the educational project MicroMath., BP.IC; 23/09812-0 - Study of the action of Pseudomonas aeruginosa secretion systems and their effectors in co-cultures with Aspergillus fumigatus, BP.IC; 23/11219-5 - Development and implementation of the educational project MicroMath, BP.IC; 23/10731-4 - Implementation of computational infrastructure for NMR spectroscopy, BP.TT; 23/06554-0 - Identification of compounds that interact with DNA gyrase from Mycobacterium tuberculosis through fragment screening, BP.IC; 23/06833-6 - Evaluating the role of aconitase in the regulation of FeS synthesis genes in Caulobacter, BP.IC; 23/06724-2 - Isolation of Pseudomonas aeruginosa lytic bacteriophages from various natural sources, BP.IC; 23/06729-4 - Training of Pseudomonas aeruginosa lytic bacteriophages to overcome bacterial resistance, BP.IC - associated scholarships

Abstract

The CEPID B3 is a network with research hubs based in São Paulo (IQ-USP, ICB-USP), Campinas (IB-UNICAMP, IAC), Ribeirão Preto (FCFRP-USP, FMRP-USP) and Rio Claro (UNESP) that will collaborate to carry out cutting edge basic research into molecular mechanisms that are of prime importance to understand bacterial reproduction, multicellular behavior, competition, colonization and interactions with their eukaryotic hosts and bacteriophages. The acquired knowledge will be used in the search and development of new chemical and biological inhibitors of bacterial growth. (AU)