The University of São Paulo twin panel: research on twins' behavior, health, and well-being

• Grant number: 22/02107-6
• Support Opportunities: Research Projects - Thematic Grants
• Duration: August 01, 2023 - July 31, 2028
• Field of knowledge: Humanities - Psychology - Human Development Psychology
• Principal Investigator: Emma Otta
• Grantee: Emma Otta
• Host Institution: Instituto de Psicologia (IP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Pesquisadores principais: Edgard Michel Crosato ; Maria de Lourdes Brizot
• Associated researchers: Ada Morgenstern ; Adela Judith Stoppel de Gueller ; Ana Alexandra Caldas Osório ; Ana Clara Falabello de Luca ; Beatriz Magalhães Wolp ; Briseida Dôgo de Resende ; Cintia Fridman Rave ; Daniela Prócida Raggio ; Fabiana Maris Versuti Stoque ; Fausto Medeiros Mendes ; Fernando Eduardo Padovan Neto ; Fraulein Vidigal de Paula ; Gabriela Bielefeld Nardoto ; Gustavo Di Giorgi Ramos ; Hélio Buchmüller Lima ; Herculano da Silva Martinho ; Hila Segal ; Isabella França Ferreira ; Joscha Kärtner ; Juliana de Lima e Silva ; Laís Ubaldo Antonio ; Laura Regina Antunes Pontes ; Lilian Cristina Luchesi ; Louise Zanella Martins ; Luciane Ribeiro de Rezende Sucasas da Costa ; Maria Elizabeth Barreto Tavares dos Reis ; Maria Lívia Tourinho Moretto ; Mariana Azevedo Carvalho ; Mariana Minatel Braga Fraga ; Mariana Pissolato ; Mario Henrique Burlacchini de Carvalho ; Mayra Antonelli Ponti ; Meiga Aurea Mendes Menezes ; Mirella Gualtieri ; Nancy Segal ; Patrícia Ferreira Monticelli ; Paulo Henrique Braz da Silva ; Plinio Almeida Barbosa ; Rana Esseily ; Roger Junges ; Rossana Pulcineli Vieira Francisco ; Sarah Cristina De Luca e Silva ; Sckarlet Ernandes Biancolin Garavazzo ; Simone Giannecchini ; Sylvia Corte Cortazzo ; Tania Kiehl Lucci ; Thais Gomes de Oliveira Machado ; Timon Jospeh Andre Lebaron-Kherif ; Vanessa Cristina de Freitas ; Vera Lúcia Jornada Krebs ; Vinicius Frayze David ; Werther Brunow de Carvalho
• Associated scholarship(s): 24/09404-1 - TT4 Twins Collection of the César Ades Phonotheque (FOCA/G), BP.TT; 24/07274-3 - Evaluation of methodologies for individualization of monozygotic twins, BP.TT; 24/00219-7 - SCIENTIFIC DISSEMINATION OF THE UNIVERSITY OF SAO PAULO TWIN PANEL: RESEARCH ON TWINS' BEHAVIOR, HEALTH, AND WELL-BEING, BP.JC; + associated scholarships 24/03950-4 - Painel USP de gêmeos: nfluence of individual preferences in addition to hygiene habits and healthy diet in Pediatric Dentistry: a discrete brush experiment (DCE) in gêmeos, BP.DD; 24/05015-0 - Care for pregnant women who have experienced the death of a fetus and maintained the pregnancy of the others, BP.TT; 24/00213-9 - Scientific dissemination of the University of São Paulo Twin Panel: Research on the Behavior, Health and Well-Being of Twins, BP.JC; 24/01823-5 - Physical and behavioral development of twin children: behavioral and physiological indicators of environmental sensitivity in an anxiety context, BP.PD; 24/03988-1 - Use of palatal rugae as a form of identification for forensic purposes in children, BP.IC; 24/00847-8 - Cesar Ades Music Library "Gêmeos" collection - Phase 1, BP.TT; 23/17085-0 - PSYCHOLOGICAL ASSISTANCE FOR PREGNANT WOMEN AT RISK THROUGH THE CLINICAL BRANCH OF THE USP TWINS PANEL, BP.TT; 23/14480-6 - STRUCTURING AND MANAGEMENT OF THE DATABASE OF THOSE REGISTERED ON PAINEL USP DE GÊMEOS: PHASE 1, BP.TT; 23/14720-7 - THE UNIVERSITY OF SÃO PAULO TWIN PANEL (PAINEL USP DE GÊMEOS): RESEARCH ON TWINS' BEHAVIOR, HEALTH AND WELL-BEING, BP.PD; 23/13188-0 - Recording of babies' cries for prosodic characterization and constitution of a scientific collection, BP.IC; 23/14957-7 - Twin Birth Registry of the Hospital das Clínicas of the University of São Paulo., BP.PD; 23/13761-1 - Development of twin children as a function of zygosity and perinatal parameters, BP.IC; 23/13242-4 - Characterization of cognitive, psychomotor, socio-emotional indicators and developmental context of twin babies., BP.TT; 23/12233-1 - Parental interaction with twins: an observational study, BP.IC; 23/12481-5 - Development of twins according to zygosity and perinatal parameters, BP.IC; 23/12035-5 - Neurobiological development of twin children: construction of the cognitive function assessment paradigm in response to stress., BP.IC - associated scholarships

Abstract

The project is a joint initiative of psychology, dentistry, and medical researchers. Objectives: Our main objective is to carry out research on twins' behavior related to health and well-being from an ontogenetic perspective (P1-P14). Methods: Sociodemographic data and self-report measures, behavioral data, and physical and physiological indicators will be collected. Salivary biomarkers (microbiome and metabolomics) and their correlations with clinical outcomes will be analyzed. Expected results: We expect to expand and organize the database of the USP Twin Panel (P1) and the Twin Birth Registry of the FMUSP's Hospital das Clinicas and to carry out analyzes of the epidemiological profile and outcomes associated with twin pregnancies (P2). The genetic profile of the participants will be determined (P3). We will present results regarding parenting styles (P4), physical and behavioral development, and stress reactions of twin children as a function of zygosity and differences in fetal development (P5, P6). Descriptions of prosodic contours of human and non-human infants cry (P7) will be presented. Additionally, we will present results on relationship styles, cooperation and competition (P8) and on anxiety in a potentially stressful situation, i.e., during dental treatment (P9). Finally, we will present data on the influence of genetic and environmental variables on the occurrence of oral health problems, the efficacy of different restorative treatments, and interventions aimed at promoting appropriate oral health behaviors, and their correlations with the dynamics of salivary biomarkers (P10-P13). We conclude with the presentation of the Clinical Branch of the USP Twin Panel (P14), and of the Educational Branch of the USP Twin Panel (P15). (AU)