Investigation and diagnosis of latent Tuberculosis in patients with lymphomas

• Grant number: 22/13331-4
• Support Opportunities: Regular Research Grants
• Start date: September 01, 2023
• End date: August 31, 2025
• Field of knowledge: Health Sciences - Collective Health - Public Health
• Principal Investigator: Sebastião Pires Ferreira Filho
• Grantee: Sebastião Pires Ferreira Filho
• Host Institution: Faculdade de Medicina (FMB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
• Associated researchers: Carlos Magno Castelo Branco Fortaleza ; Ivana Regina Gonçalves ; Márjorie de Assis Golim ; Rafael Dezen Gaiolla ; Rosana Maria Barreto Colichi

Abstract

Despite the high false-negative rates of tuberculin skin test tests, currently, in Brazil, there is no recommendation for the diagnosis of latent tuberculosis infection (LTBI) using the Interferon-Gamma Release Assays (IGRA) method in patients with lymphomas, hampering adequate investigation and treatment. Objective: to investigate and diagnose latent tuberculosis in patients with lymphomas. Method: prospective and descriptive study, with data collection in a tertiary university hospital, located in the interior of the state of São Paulo, of patients older than 18 years with lymphomas. Latent tuberculosis will be investigated through PPD and IGRA tests. Sociodemographic and clinical data such as type of lymphoma and previous contact with tuberculosis patients will be collected. (AU)