Assessing the secondary metabolites occurrence in parasitic plants and hosts

• Grant number: 22/08191-9
• Support Opportunities: Research Grants - Young Investigators Grants
• Start date: October 01, 2023
• End date: September 30, 2028
• Field of knowledge: Health Sciences - Pharmacy - Pharmacognosy
• Principal Investigator: Daniel Pecoraro Demarque
• Grantee: Daniel Pecoraro Demarque
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 24/15443-0 - Isolation of non-dereplicated parasitic plant metabolites in metabolomic analyses., BP.MS; 24/05530-2 - Isotopic labeling as a verification strategy for substance sharing between parasitic plants and their hosts, BP.IC

Abstract

Biodiversity is organized through complex interactions between the individuals in the ecosystems, which respond differently to stimuli, whether these are abiotic factors, pollution, climate change, urbanization, and others. In addition to the environmental adversities, plants also have to deal with the parasitism of their peers. The parasitism in plants is currently defined by the presence of a specialized structure produced by the parasite species to invade the host tissue, called haustoria. Through this, the parasitic plant connects its tissues with the host to exchange water, chemicals, nutrients, and even endophytic fungi. These plants, when used to produce products for human health, need a strict control, since the accumulation of substances from the host plant can occur, and vice versa. Thus, the present project aims to evaluate the transfer, accumulation and/or alteration of secondary metabolites from parasitic plants used in teas in Brazil in different hosts by means of metabolomic analysis. At the end of the project, it is expected to better understand the chemical interrelationship of these plants with their hosts. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

OLIVEIRA, EDUARDA DOS SANTOS; KOHATSU, CINTIA NAOMI; HUFNAGEL, MARIANA TEDESCO; GENNARO, VICTORIA FURLANETTO; DEMARQUE, DANIEL PECORARO. New Compounds from Terrestrial Plants: A Perspective View. COMPOUNDS, v. 4, n. 2, p. 26-pg., 2024-06-01. (22/08191-9)