In situ flow SAXS characterization of surfactant aggregates through the digestive process

• Grant number: 23/14830-7
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2024
• End date: January 31, 2026
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Watson Loh
• Grantee: Watson Loh
• Principal researcher abroad: Benjamin James Boyd
• Institution abroad: University of Copenhagen, Denmark
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated researchers: Mateus Borba Cardoso
• Associated research grant: 21/12071-6 - Tailoring colloids through supramolecular interactions: from fundamentals to applications, AP.TEM

Abstract

Monitoring changes in the self-associated systems of surfactants and electrolyte complexes during digestion can provide information on the complex molecular interactions that can occur in biological systems. However, static instrumentation can be a limitation for evaluating dynamic processes in flow. In this way, we propose the use of in situ time-resolved small-angle X-ray scattering techniques in fourth-generation facilities, to investigate and monitor our system phases transformation under flow set up. Our primary focus in this collaboration is the information exchanging and instrumental knowledge between Max IV and Sirius beamlines. The development and use new sample environments that provide insights into our system, opening possibilities to characterization of other dynamic processes. (AU)