Development of supramolecular metal-organic chemistry and devices

• Grant number: 00/06560-8
• Support Opportunities: Research Projects - Thematic Grants
• Duration: January 01, 2001 - February 28, 2005
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
• Principal Investigator: Henrique Eisi Toma
• Grantee: Henrique Eisi Toma
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

This proposal, submitted by the Laboratory of Supramolecular Chemistry and Devices of IQ-USP, is focused on the development and applications of supramolecular metal-organic systems, obtained from the assembly of multibridging subunits such as porphyrins, porphyrazins, metal clusters and functionalized polyimmin/polypyrazine complexes. In addition to the design and synthesis of new supermolecules and supramolecular systems, the research is deeply devoted to the investigation and exploitation of their relevant spectroscopic, photophysical and electrochemical properties, based on a wide variety of experimental techniques, and theoretical molecular modeling calculations. The studies are also directed to the development of applications of the supramolecular systems in photodynamic therapy (e.g. in photooxydation of DNA), catalysis and electrocatalysis (e. g. oxidation of organic substrates, cytochrome P-450 reactions, and tetraelectronic reduction of dioxygen). Finally, the supramolecular properties are exploited for the design of molecular devices such as amperometric sensors, photoelectrochemical cells and optodes. Such studies are carded out by starting from the interfacing of the molecular response with the conventional measuring devices, via the formation of thin films adsorbed onto electrode surfaces, electropolymerization, or intercalation into Prussian blue, conducting lamelar oxide matrices and composites. The research has strong interfaces with molecular electronics and bioinorganic chemistry, exploring fundamental and biomimetic aspects related to artificial photosynthesis and multielectronic redox catalysis. The proposed work is currently in progress, with the renewed support of FAPESP. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

NAUE, JEFERSON A.; TOMA, SERGIO H.; BONACIN, JULIANO A.; ARAKI, KOITI; TOMA, HENRIQUE E.. Probing the binding of tetraplatinum(pyridyl)porphyrin complexes to DNA by means of surface plasmon resonance. Journal of Inorganic Biochemistry, v. 103, n. 2, p. 182-189, Feb. 2009. (00/06560-8)

QUINTINO‚ M.S.M.; WINNISCHOFER‚ H.; ARAKI‚ K.; TOMA‚ H.E.; ANGNES‚ L.. Cobalt oxide/tetraruthenated cobalt-porphyrin composite for hydrogen peroxide amperometric sensors. ANALYST, v. 130, n. 2, p. 221-226, 2005. (00/06560-8)

Filed patent(s) as a result of this research project