Development and implementation of new methods of study of the accommodation and control of the stomach. Applications in investigations of the physiology and physiopathology of motility

• Grant number: 03/10107-5
• Support Opportunities: PRONEX Research - Thematic Grants
• Start date: July 01, 2004
• End date: September 30, 2008
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Agreement: CNPq - Pronex
• Principal Investigator: Ricardo Brandt de Oliveira
• Grantee: Ricardo Brandt de Oliveira
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Pesquisadores principais: Luiz Ernesto de Almeida Troncon ; Oswaldo Baffa Filho ; Roberto Oliveira Dantas ; Ulysses Garzella Meneghelli

Abstract

The study of gastric motility was, for a long time, undertaken only by invasive methods. But recently, non-invasive methods have been used, such as ultrasound, conventional scintillography, single photon emission tomography and nuclear magnetic resonance. Within an active group of the study of Digestive Motility, interest emerged in the implantation of these methods, in the introduction of modifications to make them more efficient, as well as the development of other techniques, such as biomagnetic. It is planned, furthermore, to determine the effect of other variables systemic in nature, such as those related to volemic homeostasis, and the relationships between motors dysfunctions of the stomach and the control of appetite and the ingestion of food, mediated by the releasing of neuropeptides, such as PYV, by endocrine cells existing in the distal part of the small intestine. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CORÁ, L. A.; ANDREIS, U.; ROMEIRO, F. G.; AMÉRICO, M. F.; OLIVEIRA, R. B.; BAFFA, O.; MIRANDA, J. R. A.. Magnetic images of the disintegration process of tablets in the human stomach by ac biosusceptometry. Physics in Medicine and Biology, v. 50, n. 23, p. 5523-5534, Dec. 2005. (03/10107-5)

ROMEIRO, F. G.; CORÁ, L. A.; ANDREIS, U. DE; AMÉRICO, M. F.; OLIVEIRA, R. B.; BAFFA, O.; MIRANDA, J. R. A.. A novel biomagnetic approach to study caecocolonic motility in humans. Neurogastroenterology and Motility, v. 18, n. 12, p. 1078-1083, Dec. 2006. (05/04345-6, 03/10107-5)

CORÁ‚ L.A.; ROMEIRO‚ F.G.; PAIXÃO‚ F.C.; AMÉRICO‚ M.F.; OLIVEIRA‚ R.B.; BAFFA‚ O.; MIRANDA‚ J.R.A.. Enteric coated magnetic HPMC capsules evaluated in human gastrointestinal tract by AC biosusceptometry. PHARMACEUTICAL RESEARCH, v. 23, n. 8, p. 1809-1816, 2006. (03/10107-5)