National Institute for Developmental Psychiatry

• Grant number: 08/57896-8
• Support type: Research Projects - Thematic Grants
• Duration: March 01, 2009 - February 28, 2015
• Field of knowledge: Health Sciences - Medicine - Psychiatry
• Cooperation agreement: CNPq - INCTs
• Principal researcher: Eurípedes Constantino Miguel Filho
• Grantee: Eurípedes Constantino Miguel Filho
• Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 12/09246-0 - Study of obsessive-compulsive disorder and other mental disorders costs in childhood, BP.DR; 11/05481-1 - Structuring the mental status exam: impact on quality of data and clinical practice, BP.PD

Abstract

Significant increases in the average Iife span have made chronic diseases a principal target of studies and interventions in the field of health care. However, there have only been few advances towards a full recovery for major psychiatric disorders. This project is designed to create strategies that promote mental health and protect the vulnerable and at-risk individuals. Mental disorders frequently begin in childhood. With this in mind, we have designed our project to provide a new framework for psychiatry in Brazil: developmental psychiatry. Developmental psychiatry is an interdisciplinary field that attempts to understand typical and atypical development, as well as the origin of developmental alterations and their expression as mental illness. The core feature of this initiative is the creation of the National Institute for Developmental Psychiatry. This institute involves a set of initiatives and research projects designed to introduce tools and methods that promote the healthy development of children and adolescents through the connection for the first time of a huge net including the best investigators on the field in our country. This Institute will introduce the precepts of developmental psychiatry into research, human resource development, outreach to the public, and the development of new technologies to achieve these objectives in partnership with the business community. We will initially describe the panorama of sociodemographic and psychopathological parameters in children and adolescents by means of a nationwide cross-sectional population-based study including the assessment of both cases and at-risk children. Special attention would be given to areas with major needs Iike the semi-arido. In an additional longitudinal study, we will follow a birth cohort until age three. Children considered to be at risk for mental disorders will be evaluated In terms of genetic and environmental factors, as well as endophenotypic risk profiles for the development of mental disorders. Underscoring the role of the institute in research and treatment, we will employ clinical trials to evaluate the efficacy of different adaptive therapeutic methods and strategies for use with children and adolescents presenting with psychiatric disorders or at-risk for them. Using translational neuroscience research as a reference, we will employ animal models to help investigate etiological factors and also to evaluate the association with candidate genes for behavioral traits. Strong emphasis will be placed on the cultivation of human resources which are currently in short supply in the area of child and adolescent mental health in the country. Various programs are proposed in to integrate the principals of developmental psychiatry into the training of mental health professionals, postgraduate medical students, public school personnel, family health care workers. For the dissemination of knowledge in the mental health field, we will devise and apply tools allowing for the appropriate use of telemedicine. The heart of this initiative 15 based in the northeast part of the country. We plan to employ an electronic medical records system to help integrate and provide more efficient accessibility to the information generated by our proposed research activities. We also plan to evaluate the costs of the prophylactic and therapeutic interventions that can then be used towards more efficient planning and management of mental health programs by governmental authorities. Therefore, using observational and experimental studies coupled with modules that are focused on teaching and improving therapy, along with the development of new technologies to achieve these objectives, we pro pose to establish a comprehensive institute that will explore a broader psychiatry that addresses the problems encountered at the individual and collective levels. In conclusion, we believe that the projects proposed here towards focus on developmental psychiatry will help building closer ties between child and adolescent psychiatrists and those who treat adults. This work will also help all of those in their respective mental health fields to have a better understanding of the natural course of mental wellness and mental disorders over the human lifespan. (AU)

Scientific publications

(50)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

VALERIO, CAROLINA; DINIZ, JULIANA BELO; FOSSALUZA, VICTOR; DE MATHIS, MARIA ALICE; BELOTTO-SILVA, CRISTINA; JOAQUIM, MARINES ALVES; MIGUEL FILHO, EURIPEDES CONSTANTINO; SHAVITT, ROSELI GEDANKE. Does anti-obsessional pharmacotherapy treat so-called comorbid depressive and anxiety states?. Journal of Affective Disorders, v. 139, n. 2, p. 187-192, JUL 2012. (08/55855-2, 08/57896-8, 08/57598-7)

DE MATHIS, MARIA ALICE; DINIZ, JULIANA B.; HOUNIE, ANA G.; SHAVITT, ROSELI G.; FOSSALUZA, VICTOR; FERRAO, YGOR; LECKMAN, JAMES F.; PEREIRA, CARLOS DE BRAGANCA; DO ROSARIO, MARIA CONCEICAO; MIGUEL, EURIPEDES C.. Trajectory in obsessive-compulsive disorder comorbidities. European Neuropsychopharmacology, v. 23, n. 7, p. 594-601, JUL 2013. (08/57896-8, 08/57598-7)

STAMATIS, CAITLIN A.; BATISTUZZO, MARCELO C.; TANAMATIS, TAIS; MIGUEL, EURIPEDES C.; HOEXTER, MARCELO Q.; TIMPANO, KIARA R.. Using supervised machine learning on neuropsychological data to distinguish OCD patients with and without sensory phenomena from healthy controls. BRITISH JOURNAL OF CLINICAL PSYCHOLOGY, v. 60, n. 1, DEC 2020. (08/57896-8, 17/50041-6)

SATO, JOAO RICARDO; BIAZOLI, JR., CLAUDINEI EDUARDO; SALUM, GIOVANNI ABRAHAO; GADELHA, ARY; CROSSLEY, NICOLAS; VIEIRA, GILSON; ZUGMAN, ANDRE; PICON, FELIPE ALMEIDA; PAN, PEDRO MARIO; HOEXTER, MARCELO QUEIROZ; et al. Association between abnormal brain functional connectivity in children and psychopathology: A study based on graph theory and machine learning. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, v. 19, n. 2, p. 119-129, 2018. (13/08531-5, 08/57896-8, 13/10498-6, 13/00506-1)

PAULA, CRISTIANE S.; MARI, JAIR J.; SANTOS BORDIN, ISABEL ALTENFELDER; MIGUEL, EURIPEDES C.; FORTES, ISABELA; BARROSO, NATALIA; ROHDE, LUIS AUGUSTO; FREIRE COUTINHO, EVANDRO SILVA. Early vulnerabilities for psychiatric disorders in elementary schoolchildren from four Brazilian regions. Social Psychiatry and Psychiatric Epidemiology, v. 53, n. 5, p. 477-486, MAY 2018. (08/57896-8)

HOFFMANN, MAURICIO SCOPE; LEIBENLUFT, ELLEN; STRINGARIS, ARGYRIS; LAPORTE, PAOLA PAGANELLA; PAN, PEDRO MARIO; GADELHA, ARY; MANFRO, GISELE GUS; MIGUEL, EURIPEDES CONSTANTINO; ROHDE, LUIS AUGUSTO; SALUM, GIOVANNI ABRAHAO. Positive Attributes Buffer the Negative Associations Between Low Intelligence and High Psychopathology With Educational Outcomes. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, v. 55, n. 1, p. 47-53, JAN 2016. (08/57896-8)

SATO, JOAO RICARDO; BIAZOLI, JR., CLAUDINEI EDUARDO; SALUM, GIOVANNI ABRAHAO; GADELHA, ARY; CROSSLEY, NICOLAS; SATTERTHWAITE, THEODORE D.; VIEIRA, GILSON; ZUGMAN, ANDRE; PICON, FELIPE ALMEIDA; PAN, PEDRO MARIO; et al. Temporal Stability of Network Centrality in Control and Default Mode Networks: Specific Associations with Externalizing Psychopathology in Children and Adolescents. Human Brain Mapping, v. 36, n. 12, p. 4926-4937, DEC 2015. (13/10498-6, 08/57896-8, 13/00506-1)

MARTEL, MICHELLE M.; PAN, PEDRO M.; HOFFMANN, MAURICIO S.; GADELHA, ARY; DO ROSARIO, MARIA C.; MARI, JAIR J.; MANFRO, GISELE G.; MIGUEL, EURIPEDES C.; PAUS, TOMAS; BRESSAN, RODRIGO A.; et al. A General Psychopathology Factor (P Factor) in Children: Structural Model Analysis and External Validation Through Familial Risk and Child Global Executive Function. JOURNAL OF ABNORMAL PSYCHOLOGY, v. 126, n. 1, p. 137-148, JAN 2017. (08/57896-8)

OTA, VANESSA KIYOMI; SANTORO, MARCOS LEITE; SPINDOLA, LETICIA MARIA; PAN, PEDRO MARIO; SIMABUCURO, ANDRESSA; XAVIER, GABRIELA; VIEIRA-FONSECA, TAMIRIS; ZANARDO, EVELIN ALINE; CAMARGO DOS SANTOS, FELIPE RODOLFO; SCHAFER, JULIA LUIZA; et al. Gene expression changes associated with trajectories of psychopathology in a longitudinal cohort of children and adolescents. TRANSLATIONAL PSYCHIATRY, v. 10, n. 1, MAR 17 2020. (16/04983-7, 08/57896-8, 14/50917-0, 14/07280-1, 17/05339-7)

ROMANI-SPONCHIADO, ALINE; VIDAL-RIBAS, PABLO; BRESSAN, RODRIGO AFFONSECA; MARI, JAIR DE JESUS; MIGUEL, EURIPEDES CONSTANTINO; GADELHA, ARY; PAIM ROHDE, LUIS AUGUSTO; EVANS-LACKO, SARA; SALUM, GIOVANNI ABRAHAO; HOFFMANN, MAURICIO SCOPEL. Longitudinal associations between positive attributes and psychopathology and their interactive effects on educational outcomes. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, SEP 2021. (14/50917-0, 08/57896-8)

DINIZ, JULIANA B.; COSTA, DANIEL L. C.; CASSAB, RAONY C. C.; PEREIRA, CARLOS A. B.; MIGUEL, EURIPEDES C.; SHAVITT, ROSELI G.. The impact of comorbid body dysmorphic disorder on the response to sequential pharmacological trials for obsessive-compulsive disorder. JOURNAL OF PSYCHOPHARMACOLOGY, v. 28, n. 6, p. 603-611, JUN 2014. (11/21357-9, 08/57896-8, 11/00968-0)

PAULA, CRISTIANE S.; COUTINHO, EVANDRO S.; MARI, JAIR J.; ROHDE, LUIS A.; MIGUEL, EURIPEDES C.; BORDIN, ISABEL A.. Prevalence of psychiatric disorders among children and adolescents from four Brazilian regions. Revista Brasileira de Psiquiatria, v. 37, n. 2, p. 178-179, APR-JUN 2015. (08/57896-8)

MOURA, L. M.; CROSSLEY, N. A.; ZUGMAN, A.; PAN, P. M.; GADELHA, A.; DEL AQUILLA, M. A. G.; PICON, F. A.; ANES, M.; AMARO, JR., E.; DE JESUS MARI, J.; et al. Coordinated brain development: exploring the synchrony between changes in grey and white matter during childhood maturation. BRAIN IMAGING AND BEHAVIOR, v. 11, n. 3, p. 808-817, JUN 2017. (13/08531-5, 13/10498-6, 08/57896-8, 13/00506-1)

COELHO, ROBERTA; LEVANDOWSKI, MATEUS L.; MANSUR, RODRIGO B.; DA CUNHA, GRACCIELLE RODRIGUES; ASEVEDO, ELSON; ZUGMAN, ANDRE; SALUM, GIOVANNI A.; GADELHA, ARY; PAN, PEDRO M.; RIZZO, LUCAS B.; et al. Serum copeptin in children exposed to maltreatment. PSYCHIATRY AND CLINICAL NEUROSCIENCES, v. 70, n. 10, p. 434-441, OCT 2016. (08/57896-8)

SAAD, LAURA O.; DO ROSARIO, MARIA C.; CESAR, RAONY C.; BATISTUZZO, MARCELO C.; HOEXTER, MARCELO Q.; MANFRO, GISELE G.; SHAVITT, ROSELI G.; LECKMAN, JAMES F.; MIGUEL, EURIPEDES C.; ALVARENGA, PEDRO G.. The Child Behavior Checklist-Obsessive-Compulsive Subscale Detects Severe Psychopathology and Behavioral Problems Among School-Aged Children. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, v. 27, n. 4, p. 342-348, MAY 2017. (08/57896-8)

FORTES, ISABELA S.; PAULA, CRISTIANE S.; OLIVEIRA, MELAINE C.; BORDIN, ISABEL A.; MARI, JAIR DE JESUS; ROHDE, LUIS A.. A cross-sectional study to assess the prevalence of DSM-5 specific learning disorders in representative school samples from the second to sixth grade in Brazil. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, v. 25, n. 2, p. 195-207, FEB 2016. (08/57896-8)

HOFFMANN, MAURICIO SCOPEL; PAN, PEDRO MARIO; MANFRO, GISELE GUS; MARI, JAIR DE JESUS; MIGUEL, EURIPEDES CONSTANTINO; BRESSAN, RODRIGO AFFONSECA; ROHDE, LUIS AUGUSTO; SALUM, GIOVANNI ABRAHAO. Cross-Sectional and Longitudinal Associations of Temperament and Mental Disorders in Youth. CHILD PSYCHIATRY & HUMAN DEVELOPMENT, v. 50, n. 3, p. 374-383, JUN 2019. (08/57896-8, 14/50917-0)

GIOVANNI A. SALUM; DIOGO ARAÚJO DESOUSA; GISELE GUS MANFRO; PEDRO MARIO PAN; ARY GADELHA; ELISA BRIETZKE; EURÍPEDES CONSTANTINO MIGUEL; JAIR J. MARI; MARIA CONCEIÇÃO DO ROSÁRIO; RODRIGO GRASSI-OLIVEIRA. Dados de levantamento com múltiplos informantes para a mensuração de maus-tratos na infância: uma análise fatorial confirmatória de segunda ordem. Trends in Psychiatry and Psychotherapy, v. 38, n. 1, p. 23-32, 2016-03-18. (08/57896-8)

AXELRUD, LUIZA KVITKO; SATO, JOAO RICARDO; SANTORO, MARCOS LEITE; TALARICO, FERNANDA; PINE, DANIEL SAMUEL; ROHDE, LUIS AUGUSTO; ZUGMAN, ANDRE; AMARO, JR., EDSON; BRESSAN, RODRIGO AFFONSECA; GRASSI-OLIVEIRA, RODRIGO; et al. Genetic risk for Alzheimer's disease and functional brain connectivity in children and adolescents. NEUROBIOLOGY OF AGING, v. 82, p. 10-17, OCT 2019. (08/57896-8)

CARVALHO, CAROLINA MUNIZ; PAN, PEDRO M.; OTA, VANESSA K.; SPINDOLA, LETICIA M.; XAVIER, GABRIELA; SANTORO, MARCOS L.; MAZZOTTI, DIEGO R.; PELLEGRINO, RENATA; HAKONARSON, HAKON; ROHDE, LUIS AUGUSTO; et al. Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders. PSYCHIATRY RESEARCH, v. 273, p. 575-577, MAR 2019. (08/57896-8, 14/50917-0, 14/07280-1)

FATORI, DANIEL; DE BRAGANCA PEREIRA, CARLOS ALBERTO; ASBAHR, FERNANDO R.; REQUENA, GUARACI; ALVARENGA, PEDRO G.; DE MATHIS, MARIA ALICE; ROHDE, LUIS A.; LECKMAN, JAMES F.; MARCH, JOHN S.; POLANCZYK, GUILHERME V.; et al. Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial. JOURNAL OF ANXIETY DISORDERS, v. 58, p. 42-50, AUG 2018. (08/57896-8)

MIGUEL, EURIPEDES C.; MERCADANTE, MARCOS T.; GRISI, SANDRA; ROHDE, LUIZ A.. O Instituto Nacional de Ciência e Tecnologia de Psiquiatria do Desenvolvimento para a Infância e Adolescência: um novo paradigma para a Psiquiatria Brasileira tendo como foco as nossas crianças e o seu futuro. Revista Brasileira de Psiquiatria, v. 31, n. 2, p. 85-88, 2009. (08/57896-8)

ZIEBOLD, CAROLINA; EVANS-LACKO, SARA; REZENDE ANDRADE, MARIO CESAR; HOFFMANN, MAURICIO; FONSECA, LAIS; BARBOSA, MATHEUS; PAN, PEDRO MARIO; MIGUEL, EURIPEDES; BRESSAN, RODRIGO; ROHDE, LUIS AUGUSTO; et al. Childhood poverty and mental health disorders in early adulthood: evidence from a Brazilian cohort study. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, DEC 2021. (08/57896-8, 14/50917-0)

MANFRO, ARTHUR GUS; PINE, DANIEL S.; POLANCZYK, GUILHERME VANONI; SANTORO, MARCOS; SMOLLER, JORDAN WASSERTHEIL; KOENEN, KARESTAN; MARI, JAIR; PAN, PEDRO MARIO; ZUGMAN, ANDRE; SCHAFER, JULIA LUIZA; et al. Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, v. 60, n. 12, p. 1501-1512, DEC 2021. (08/57896-8)

MACUL FERREIRA DE BARROS, PEDRO; DO ROSARIO, MARIA CONCEICAO; SZEJKO, NATALIA; POLGA, NATALIA; REQUENA, GUARACI DE LIMA; RAVAGNANI, BEATRIZ; FATORI, DANIEL; BATISTUZZO, MARCELO CAMARGO; HOEXTER, MARCELO QUEIROZ; ROHDE, LUIS AUGUSTO; et al. Risk factors for obsessive-compulsive symptoms. Follow-up of a community-based youth cohort. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, v. 30, n. 1, FEB 2020. (15/01587-0, 08/57896-8)

HOEXTER, MARCELO Q.; BIAZOLI, JR., CLAUDINEI E.; ALVARENGA, PEDRO G.; BATISTUZZO, MARCELO C.; SALUM, GIOVANNI A.; GADELHA, ARY; PAN, PEDRO M.; ANES, MAURICIO; MANCINI-MARTINS, LETICIA; MOURA, LUCIANA M.; et al. Low frequency fluctuation of brain spontaneous activity and obsessive compulsive symptoms in a large school-age sample. JOURNAL OF PSYCHIATRIC RESEARCH, v. 96, p. 224-230, JAN 2018. (13/08531-5, 08/57896-8, 13/00506-1, 16/05865-8, 16/02246-5, 13/10498-6, 12/50722-0)

AXELRUD, LUIZA KVITKO; SIMIONI, ANDRE RAFAEL; PINE, DANIEL SAMUEL; WINKLER, ANDERSON MARCELO; PAN, PEDRO MARIO; SATO, JOAO RICARDO; ZUGMAN, ANDRE; PARKER, NADINE; PICON, FELIPE; JACKOWSKI, ANDREA; et al. Neuroimaging Association Scores: reliability and validity of aggregate measures of brain structural features linked to mental disorders in youth. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, v. 30, n. 12, p. 1895-1906, DEC 2021. (08/57896-8)

BIAZOLI JR, CLAUDINEI EDUARDO; SALUM, GIOVANNI ABRAHAO; GADELHA, ARY; REBELLO, KEILA; MOURA, LUCIANA MONTEIRO; PAN, PEDRO MARIO; BRIETZKE, ELISA; MIGUEL, EURIPEDES CONSTANTINO; ROHDE, LUIS AUGUSTO; BRESSAN, RODRIGO AFFONSECA; et al. Socioeconomic status in children is associated with spontaneous activity in right superior temporal gyrus. BRAIN IMAGING AND BEHAVIOR, v. 14, n. 4, p. 961-970, AUG 2020. (13/08531-5, 13/10498-6, 08/57896-8, 13/00506-1)

MORIYAMA, TAIS SILVEIRA; VAN OS, JIM; GADELHA, ARY; PAN, PEDRO MARIO; SALUM, GIOVANNI ABRAHAO; MANFRO, GISELA GUS; MARI, JAIR DE JESUS; MIGUEL, EURIPEDES CONSTANTINO; ROHDE, LUIS AUGUSTO; POLANCZYK, GUILHERME VANONI; et al. Differences Between Self-Reported Psychotic Experiences, Clinically Relevant Psychotic Experiences, and Attenuated Psychotic Symptoms in the General Population. FRONTIERS IN PSYCHIATRY, v. 10, OCT 29 2019. (08/57896-8)

SHANNAHOFF-KHALSA, DAVID; FERNANDES, RODRIGO YACUBIAN; PEREIRA, CARLOS A. DE B.; MARCH, JOHN S.; LECKMAN, JAMES F.; GOLSHAN, SHAHROKH; VIEIRA, MARIO S. R.; POLANCZYK, V, GUILHERME; MIGUEL, EURIPEDES C.; SHAVITT, ROSELI G.. Kundalini Yoga Meditation Versus the Relaxation Response Meditation for Treating Adults With Obsessive-Compulsive Disorder: A Randomized Clinical Trial. FRONTIERS IN PSYCHIATRY, v. 10, NOV 11 2019. (08/57896-8)

MORIYAMA, TAIS SILVEIRA; DRUKKER, MARJAN; GADELHA, ARY; PAN, PEDRO MARIO; SALUM, GIOVANNI ABRAHAO; MANFRO, GISELE GUS; MARI, JAIR DE JESUS; MIGUEL, EURIPEDES CONSTANTINO; ROHDE, LUIS AUGUSTO; POLANCZYK, GUILHERME VANONI; et al. The association between psychotic experiences and traumatic life events: the role of the intention to harm. PSYCHOLOGICAL MEDICINE, v. 48, n. 13, p. 2235-2246, OCT 2018. (08/57896-8)

HOFFMANN, MAURICIO SCOPEL; PAN, PEDRO MARIO; MANFRO, GISELE GUS; MARI, JAIR DE JESUS; MIGUEL, EURIPEDES CONSTANTINO; BRESSAN, RODRIGO AFFONSECA; ROHDE, LUIS AUGUSTO; SALUM, GIOVANNI ABRAHAO. Independent and interactive associations of temperament dimensions with educational outcomes in young adolescents. LEARNING AND INDIVIDUAL DIFFERENCES, v. 78, FEB 2020. (08/57896-8)

SALUM, GIOVANNI A.; POLANCZYK, GUILHERME V.; MIGUEL, EURIPEDES C.; ROHDE, LUIS A. P.. Effects of childhood development on late-life mental disorders. CURRENT OPINION IN PSYCHIATRY, v. 23, n. 6, p. 498-503, NOV 2010. (08/57896-8)

LUCIO, P. S.; SALUM, G. A.; ROHDE, L. A.; SWARDFAGER, W.; GADELHA, A.; VANDEKERCKHOVE, J.; PAN, P. M.; POLANCZYK, G. V.; DO ROSARIO, M. C.; JACKOWSKI, A. P.; et al. Poor stimulus discriminability as a common neuropsychological deficit between ADHD and reading ability in young children: a moderated mediation model. PSYCHOLOGICAL MEDICINE, v. 47, n. 2, p. 255-266, JAN 2017. (08/57896-8)

RESENDE, L. S.; AMARAL, C. E.; SOARES, R. B. S.; ALVES, A. S.; ALVES-DOS-SANTOS, L.; BRITTO, L. R. G.; CHIAVEGATTO, S.. Social stress in adolescents induces depression and brain-region-specific modulation of the transcription factor MAX. TRANSLATIONAL PSYCHIATRY, v. 6, OCT 11 2016. (08/57896-8, 09/01333-8)

MOGG, K.; SALUM, G. A.; BRADLEY, B. P.; GADELHA, A.; PAN, P.; ALVARENGA, P.; ROHDE, L. A.; PINE, D. S.; MANFRO, G. G.. Attention network functioning in children with anxiety disorders, attention-deficit/hyperactivity disorder and non-clinical anxiety. PSYCHOLOGICAL MEDICINE, v. 45, n. 12, p. 2633-2646, SEP 2015. (08/57896-8)

LUCIO, PATRICIA S.; SALUM, GIOVANNI; SWARDFAGER, WALTER; MARI, JAIR DE JESUS; PAN, PEDRO M.; BRESSAN, RODRIGO A.; GADELHA, ARY; ROHDE, LUIS A.; COGO-MOREIRA, HUGO. Testing Measurement Invariance across Groups of Children with and without Attention-Deficit/Hyperactivity Disorder: Applications for Word Recognition and Spelling Tasks. FRONTIERS IN PSYCHOLOGY, v. 8, OCT 25 2017. (08/57896-8)

SAMPAIO, ALINE SANTOS; HOUNIE, ANA GABRIELA; PETRIBU, KATIA; CAPPI, CAROLINA; MORAIS, IVANIL; VALLADA, HOMERO; DO ROSARIO, MARIA CONCEICAO; STEWART, S. EVELYN; FARGENESS, JESEN; MATHEWS, CAROL; et al. COMT and MAO-A Polymorphisms and Obsessive-Compulsive Disorder: A Family-Based Association Study. PLoS One, v. 10, n. 3, MAR 20 2015. (08/57896-8)

ALVARENGA, PEDRO G.; CESAR, RAONY C.; LECKMAN, JAMES F.; MORIYAMA, TAIS S.; TORRES, ALBINA R.; BLOCH, MICHAEL H.; COUGHLIN, CATHERINE G.; HOEXTER, MARCELO Q.; MANFRO, GISELE G.; POLANCZYK, GUILHERME V.; et al. Obsessive-compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged children. JOURNAL OF PSYCHIATRIC RESEARCH, v. 62, p. 108-114, MAR 2015. (08/57896-8)

SALUM, GIOVANNI ABRAHAO; GADELHA, ARY; PAN, PEDRO MARIO; MORIYAMA, TAIS SILVEIRA; GRAEFF-MARTINS, ANA SOLEDADE; TAMANAHA, ANA CARINA; ALVARENGA, PEDRO; KRIEGER, FERNANDA VALLE; FLEITLICH-BILYK, BACY; JACKOWSKI, ANDREA; et al. High risk cohort study for psychiatric disorders in childhood: rationale, design, methods and preliminary results. INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, v. 24, n. 1, p. 58-73, MAR 2015. (08/57896-8)

PAOLA P. LAPORTE; PEDRO M. PAN; MAURICIO S. HOFFMANN; LAUREN S. WAKSCHLAG; LUIS A. ROHDE; EURIPEDES C. MIGUEL; DANIEL S. PINE; GISELE G. MANFRO; GIOVANNI A. SALUM. Specific and social fears in children and adolescents: separating normative fears from problem indicators and phobias. Revista Brasileira de Psiquiatria, v. 39, n. 2, p. 118-125, 2017-03-09. (08/57896-8)

CUNHA, G. R.; ASEVEDO, E.; MANSUR, R. B.; ZUGMAN, A.; PAN, P. M.; GADELHA, A.; BELANGERO, S. I.; RIZZO, L. B.; COELHO, R.; STERTZ, L.; et al. Inflammation, neurotrophism and oxidative stress and childhood psychopathology in a large community sample. ACTA PSYCHIATRICA SCANDINAVICA, v. 133, n. 2, p. 122-132, FEB 2016. (08/57896-8)

SATO, JOAO RICARDO; BIAZOLI, JR., CLAUDINEI EDUARDO; SALUM, GIOVANNI ABRAHAO; GADELHA, ARY; CROSSLEY, NICOLAS; VIEIRA, GILSON; ZUGMAN, ANDRE; PICON, FELIPE ALMEIDA; PAN, PEDRO MARIO; HOEXTER, MARCELO QUEIROZ; et al. Connectome hubs at resting state in children and adolescents: Reproducibility and psychopathological correlation. DEVELOPMENTAL COGNITIVE NEUROSCIENCE, v. 20, p. 2-11, AUG 2016. (13/08531-5, 13/10498-6, 08/57896-8, 13/00506-1)

LIMA, LEANDRO DE ARAUJO; FEIO-DOS-SANTOS, ANA CECILIA; BELANGERO, SINTIA IOLE; GADELHA, ARY; BRESSAN, RODRIGO AFFONSECA; SALUM, GIOVANNI ABRAHAO; PAN, PEDRO MARIO; MORIYAMA, TAIS SILVEIRA; GRAEFF-MARTINS, ANA SOLEDADE; TAMANAHA, ANA CARINA; et al. An integrative approach to investigate the respective roles of single-nucleotide variants and copy-number variants in Attention-Deficit/Hyperactivity Disorder. SCIENTIFIC REPORTS, v. 6, MAR 7 2016. (08/57896-8)

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MASCHIETTO, MARIANA; BASTOS, LAURA CAROLINE; TAHIRA, ANA CAROLINA; BASTOS, ELEN PEREIRA; VALE EUCLYDES, VERONICA LUIZA; BRENTANI, ALEXANDRA; FINK, GUNTHER; DE BAUMONT, ANGELICA; FELIPE-SILVA, ALOSIO; VIEIRA FRANCISCO, ROSSANA PULCINELI; et al. Sex differences in DNA methylation of the cord blood are related to sex-bias psychiatric diseases. SCIENTIFIC REPORTS, v. 7, MAR 17 2017. (15/06281-7, 08/57896-8, 12/19472-7)

BLANCO-VIEIRA, THIAGO; HOEXTER, MARCELO QUEIROZ; BATISTUZZO, MARCELO C.; ALVARENGA, PEDRO; SZEJKO, NATALIA; FUMO, AFONSO MAZINE TIAGO; MIGUEL, EURIPEDES C.; DO ROSARIO, MARIA CONCEICAO. Association Between Obsessive-Compulsive Symptom Dimensions in Mothers and Psychopathology in Their Children. FRONTIERS IN PSYCHIATRY, v. 12, JUN 28 2021. (08/57896-8)

HOFFMANN, MAURICIO SCOPEL; MCDAID, DAVID; SALUM, GIOVANNI ABRAHAO; SILVA-RIBEIRO, WAGNER; ZIEBOLD, CAROLINA; KING, DEREK; GADELHA, ARY; MIGUEL, EURIPEDES CONSTANTINO; MARI, JAIR DE JESUS; ROHDE, LUIS AUGUSTO; et al. The impact of child psychiatric conditions on future educational outcomes among a community cohort in Brazil. EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES, v. 30, OCT 28 2021. (14/50917-0, 08/57896-8)

SIMIONI, ANDRE R.; PAN, PEDRO M.; GADELHA, ARY; MANFRO, GISELE G.; MARI, JAIR J.; MIGUEL, EURIPEDES C.; ROHDE, LUIS A.; SALUM, GIOVANNI A.. Prevalence, clinical correlates and maternal psychopathology of deliberate self-harm in children and early adolescents: results from a large community study. Revista Brasileira de Psiquiatria, v. 40, n. 1, p. 48-55, JAN-MAR 2018. (08/57896-8)