Obtaining anthocyanins, carotenoids, flavonoids, volatile oils, and tocotrienols by supercritical technology: process parameters and chemical characterization of extracts

• Grant number: 09/17234-9
• Support Opportunities: Regular Research Grants
• Start date: June 01, 2010
• End date: August 31, 2012
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Engineering
• Principal Investigator: Maria Angela de Almeida Meireles Petenate
• Grantee: Maria Angela de Almeida Meireles Petenate
• Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• City of the host institution: Campinas

Abstract

Obtaining bioactive compounds from biological matrices by supercritical extraction, a green technology with many advantages is technically feasible for several biological matrices. Supercritical technology is viable for the production of ingredients for the food, cosmeceuticals and pharmaceuticals industries. In Brazil, the quantity and quality of research in this area are significant. But in our country there are no industries employing this technology for the production of extracts. One reason is association of this technology with higher investments. Studies done at LASEFI/DEA/FEA/UNICAMP have shown that this technology is economically feasible in our country for the production of bioactive extracts. Aiming to spread to the Productive Sector the advantages of supercritical technology we intend to develop a systematic study on the scaling-up to obtain plant extracts with antioxidant activity and to characterize these extracts. The studies of scale-up will be conducted using two extraction units: (1) Unit SFE 2×1L assembled in LASEFI with support from CNPq (Call MCT/CNPq 02/2006 - Universal; registration 472023/2006-3) and (2) unit SFE 2×5L obtained with support from the project PITE - FAPESP 05/60485-1/. The use of two extraction units will allow the transposition of data from laboratory scale (extracting maximum volume equal to 300 mL) for a semi-pilot and later to a pilot scale. The extracts will be characterized with respect to their chemical composition and antioxidant activity; thus, these parameters will be used for the quality control of the process. (AU)

Scientific publications

(18)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

SANTOS, DIEGO TRESINARI; DE ALMEIDA MEIRELES, MARIA ANGELA. Developing novel one-step processes for obtaining food-grade O/W emulsions from pressurized fluid extracts: processes description, state of the art and perspectives. FOOD SCIENCE AND TECHNOLOGY, v. 35, n. 4, p. 579-587, OCT-DEC 2015. (12/10685-8, 12/19304-7, 10/16485-5, 09/17234-9)

J. Q. ALBARELLI; A. MIAN; D. T. SANTOS; A. V. ENSINAS; F. MARÉCHAL; M. A. A. MEIRELES. Multi-objective Optimization of Supercritical Water Gasification of Leftover Brazilian Ginseng Roots After Phytochemical Recovery Steps. Brazilian Journal of Chemical Engineering, v. 34, n. 3, p. 841-850, 2017-07-00. (10/16485-5, 09/17234-9, 15/06954-1, 13/18114-2, 12/19304-7, 12/10685-8)

FARIAS-CAMPOMANES, ANGELA M.; ROSTAGNO, MAURICIO A.; MEIRELES, M. ANGELA A.. Production of polyphenol extracts from grape bagasse using supercritical fluids: Yield, extract composition and economic evaluation. JOURNAL OF SUPERCRITICAL FLUIDS, v. 77, p. 70-78, MAY 2013. (09/17234-9)

VARDANEGA, RENATA; CARVALHO, PEDRO I. N.; ALBARELLI, JULIANA Q.; SANTOS, DIEGO T.; MEIRELES, ANGELA A.. Techno-economic evaluation of obtaining Brazilian ginseng extracts in potential production scenarios. FOOD AND BIOPRODUCTS PROCESSING, v. 101, p. 45-55, JAN 2017. (12/19304-7, 15/06954-1, 12/10685-8, 10/16485-5, 09/17234-9, 13/18114-2)

ALBARELLI, J. Q.; MIAN, A.; SANTOS, D. T.; ENSINAS, A. V.; MARECHAL, F.; MEIRELES, M. A. A.. MULTI-OBJECTIVE OPTIMIZATION OF SUPERCRITICAL WATER GASIFICATION OF LEFTOVER BRAZILIAN GINSENG ROOTS AFTER PHYTOCHEMICAL RECOVERY STEPS. Brazilian Journal of Chemical Engineering, v. 34, n. 3, p. 10-pg., 2017-07-01. (15/06954-1, 12/10685-8, 10/16485-5, 09/17234-9, 12/19304-7, 13/18114-2)

ALBUQUERQUE, CAROLINA L. C.; MEIRELES, M. ANGELA A.. Defatting of annatto seeds using supercritical carbon dioxide as a pretreatment for the production of bixin: Experimental, modeling and economic evaluation of the process. JOURNAL OF SUPERCRITICAL FLUIDS, v. 66, p. 10-pg., 2012-06-01. (09/17234-9)

SANTOS, DIEGO T.; ALBARELLI, JULIANA Q.; ROSTAGNO, MAURICIO A.; ENSINAS, ADRIANO V.; MARECHAL, FRANCOIS; MEIRELES, M. ANGELA A.. New proposal for production of bioactive compounds by supercritical technology integrated to a sugarcane biorefinery. Clean Technologies and Environmental Policy, v. 16, n. 7, p. 14-pg., 2014-10-01. (13/15049-5, 10/16485-5, 09/17234-9, 12/19304-7, 12/10685-8)

ROSA, M. THEREZA M. G.; SILVA, ERIC KEVEN; SANTOS, DIEGO T.; PETENATE, ADEMIR J.; MEIRELES, M. ANGELA A.. Obtaining annatto seed oil miniemulsions by ultrasonication using aqueous extract from Brazilian ginseng roots as a biosurfactant. Journal of Food Engineering, v. 168, p. 68-78, JAN 2015. (09/17234-9, 12/10685-8, 12/19304-7, 10/16485-5)

RODRIGUES, LIARA M.; ALCAZAR-ALAY, SYLVIA C.; PETENATE, ADEMIR J.; MEIRELES, MARIA ANGELA A.. Bixin extraction from defatted annatto seeds. COMPTES RENDUS CHIMIE, v. 17, n. 3, p. 268-283, MAR 2014. (09/17234-9, 12/10685-8)

SANTOS, DIEGO T.; ALBARELLI, JULIANA Q.; ROSTAGNO, MAURICIO A.; ENSINAS, ADRIANO V.; MARECHAL, FRANCOIS; MEIRELES, M. ANGELA A.. New proposal for production of bioactive compounds by supercritical technology integrated to a sugarcane biorefinery. Clean Technologies and Environmental Policy, v. 16, n. 7, SI, p. 1455-1468, OCT 2014. (12/19304-7, 13/15049-5, 12/10685-8, 10/16485-5, 09/17234-9)

ZABOT, GIOVANI L.; MORAES, MOYSES N.; PETENATE, ADEMIR J.; MEIRELES, M. ANGELA A.. Influence of the bed geometry on the kinetics of the extraction of clove bud oil with supercritical CO2. JOURNAL OF SUPERCRITICAL FLUIDS, v. 93, n. SI, p. 56-66, SEP 2014. (09/17234-9, 11/23665-2)

ALBUQUERQUE, CAROLINA L. C.; MEIRELES, M. ANGELA A.. Defatting of annatto seeds using supercritical carbon dioxide as a pretreatment for the production of bixin: Experimental, modeling and economic evaluation of the process. JOURNAL OF SUPERCRITICAL FLUIDS, v. 66, n. SI, p. 86-95, JUN 2012. (09/17234-9)

ALBARELLI, J. Q.; MIAN, A.; SANTOS, D. T.; ENSINAS, A. V.; MARECHAL, F.; MEIRELES, M. A. A.. MULTI-OBJECTIVE OPTIMIZATION OF SUPERCRITICAL WATER GASIFICATION OF LEFTOVER BRAZILIAN GINSENG ROOTS AFTER PHYTOCHEMICAL RECOVERY STEPS. Brazilian Journal of Chemical Engineering, v. 34, n. 3, p. 841-850, JUL-SEP 2017. (12/19304-7, 12/10685-8, 15/06954-1, 10/16485-5, 09/17234-9, 13/18114-2)

SANTOS, DIEGO TRESINARI; DE ALMEIDA MEIRELES, MARIA ANGELA. Developing novel one-step processes for obtaining food-grade O/W emulsions from pressurized fluid extracts: processes description, state of the art and perspectives. FOOD SCIENCE AND TECHNOLOGY, v. 35, n. 4, p. 9-pg., 2015-10-01. (10/16485-5, 09/17234-9, 12/19304-7, 12/10685-8)

ZABOT, GIOVANI L.; MORAES, MOYSES N.; PETENATE, ADEMIR J.; MEIRELES, M. ANGELA A.. Influence of the bed geometry on the kinetics of the extraction of clove bud oil with supercritical CO2. JOURNAL OF SUPERCRITICAL FLUIDS, v. 93, p. 11-pg., 2014-09-01. (09/17234-9, 11/23665-2)

SANTOS, DIEGO T.; VARDANEGA, RENATA; ALBARELLI, JULIANA Q.; ENSINAS, ADRIANO V.; MARECHAL, FRANCOIS; MEIRELES, M. ANGELA A.; VARBANOV, P; KLEMES, JJ; SEFERLIS, P; PAPADOPOULOS, AI; et al. Energy Consumption Versus Antioxidant Activity of Pressurized Fluid Extracts from Pfaffia glomerata Roots. 16TH INTERNATIONAL CONFERENCE ON PROCESS INTEGRATION, MODELLING AND OPTIMISATION FOR ENERGY SAVING AND POLLUTION REDUCTION (PRES'13), v. 35, p. 6-pg., 2013-01-01. (12/10685-8, 12/19304-7, 10/16485-5, 09/17234-9)

SANTOS, DIEGO T.; BARBOSA, DAYANE F.; VARDANEGA, RENATA; ALBARELLI, JULIANA Q.; MEIRELES, M. ANGELA A.. Experimental and Simulation Study on Formulation of Clove Essential Oil Products Using Alternative Surfactant. JOURNAL OF COLLOID SCIENCE AND BIOTECHNOLOGY, v. 2, n. 2, p. 11-pg., 2013-06-01. (12/10685-8, 12/19304-7, 10/16485-5, 09/17234-9)

SANTOS, DIEGO T.; BARBOSA, DAYANE F.; VARDANEGA, RENATA; GOMES, M. THEREZA M. S.; MEIRELES, M. ANGELA A.. Novel Method to Produce Emulsions Containing Essential Oils from Saponin-Rich Pressurized Aqueous Plant Extracts. JOURNAL OF COLLOID SCIENCE AND BIOTECHNOLOGY, v. 2, n. 2, p. 7-pg., 2013-06-01. (12/10685-8, 12/19304-7, 10/16485-5, 09/17234-9)

Filed patent(s) as a result of this research project