Study about the effects of the Tribulus terrestris and Tibolona used in the treatment of women with sexual desire dysfunctions after menopause

• Grant number: 09/02773-1
• Support Opportunities: Regular Research Grants
• Start date: September 01, 2009
• End date: August 31, 2011
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Sonia Maria Rolim Rosa Lima
• Grantee: Sonia Maria Rolim Rosa Lima
• Host Institution: Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). Fundação Arnaldo Vieira de Carvalho. São Paulo , SP, Brazil

Abstract

Sexuality is an essential part of each human being's personality: it exercises influence on thoughts, feelings, actions and integration. Consequently, it influences the physical and mental health. It is estimated that 43% of all women present at least one complaint about sexual problems. The disturbances in desire and arousal are among the most commonly presented clinical gynecology problems. Medicinal plants have been utilized for therapeutic purposes for millions of years, where many of such plants have been described as having aphrodisiac properties. The Tribulus terrestris is a medicinal plant native from India, which its active principle is protodioscin (PTN). , is recommended for the treatment against infertility, low libido and sexual impotence. While the effects of the estrogen in the neuroendocrine and trophism of genital organs have been well established, the contribution of androgens to the female physical and mental well-being is still subject of discussion. Many studies suggest that the Tibolona can improve the sexual function. This is plausible due to the fact that the testosterone has demonstrated that increases the libido and the frequency of sexual activity, where the Tibolona is also known to have androgenic activity. Women after menopause present a 30% reduction in the levels of testosterone circulation when compared to the pre-menopause period. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

POSTIGO, SOSTENES; ROLIM ROSA LIMA, SONIA MARIA; YAMADA, SILVIA SAITO; DOS REIS, BENEDITO FABIANO; DUTRA DA SILVA, GUSTAVO MAXIMILIANO; AOKI, TSUTOMU. Avaliação dos efeitos do Tribulus Terrestris na sexualidade de mulheres no climatério. Revista Brasileira de Ginecologia e Obstetrícia, v. 38, n. 3, p. 140-146, MAR 2016. (09/02773-1)