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Genome wide association study for reproductive traits in zebu bulls (Bos indicus) using high-density SNP chip

Abstract

Several studies in quantitative genetics and functional genomics have demonstrated that the Genome Wide Association Study (GWAS) allows the identification of molecular markers useful in animal selection, enhancing the genetic gain in breeding programs. This technique allows the identification of genetic markers associated with specific phenotypes, such as semen quality and sperm cryotolerance, useful for early, efficient and reliable selection, thereby increasing productivity and profitability of livestock systems. The use of advanced molecular tools, such as SNP chip, has maximized the benefits of marker assisted selection, allowing uniform coverage of the genome for thousands of markers simultaneously, providing dense and highly informative genomic maps. Taking into consideration the current need of the beef production chain to shorten production cycles by selecting superior animals with better reproductive performance at early age, this project proposes the identification of molecular markers associated with semen quality and sperm cryotolerance in zebu sires using the high-density (HD) SNP chip technology. (AU)

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Scientific publications (14)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
TRIGO, BEATRIZ B.; UTSUNOMIYA, ADAM T. H.; FORTUNATO, ALVARO A. A. D.; MILANESI, MARCO; TORRECILHA, RAFAELA B. P.; LAMB, HARRISON; NGUYEN, LOAN; ROSS, ELIZABETH M.; HAYES, BEN; PADULA, ROMULO C. M.; SUSSAI, THAYLA S.; ZAVAREZ, LUDMILLA B.; CIPRIANO, RAFAEL S.; CAMINHAS, MARIA M. T.; LOPES, FLAVIA L.; PELLE, CASSIANO; LEEB, TOSSO; BANNASCH, DANIKA; BICKHART, DEREK; SMITH, TIMOTHY P. L.; SONSTEGARD, TAD S.; GARCIA, JOSE F.; UTSUNOMIYA, YURI T. Variants at the ASIP locus contribute to coat color darkening in Nellore cattle. GENETICS SELECTION EVOLUTION, v. 53, n. 1 APR 28 2021. Web of Science Citations: 0.
AGUIAR, TAMIRIS SAYURI; PINTOR TORRECILHA, RAFAELA BEATRIZ; MILANESI, MARCO; HARTH UTSUNOMIYA, ADAM TAITI; TRIGO, BEATRIZ BATISTA; TIJJANI, ABDULFATAI; MUSA, HASSAN HUSSEIN; LOPES, FLAVIA LOMBARDI; AJMONE-MARSAN, PAOLO; CARVALHEIRO, ROBERTO; DE REZENDE NEVES, HAROLDO HENRIQUE; DO CARMO, ADRIANA SANTANA; HANOTTE, OLIVIER; SONSTEGARD, TAD STEWART; GARCIA, JOSE FERNANDO; UTSUNOMIYA, YURI TANI. Association of Copy Number Variation at Intron 3 of HMGA2 With Navel Length in Bos indicus. FRONTIERS IN GENETICS, v. 9, DEC 7 2018. Web of Science Citations: 1.
UTSUNOMIYA, YURI TANI; MILANESI, MARCO; HARTH UTSUNOMIYA, ADAM TAITI; PINTOR TORRECILHA, RAFAELA BEATRIZ; KIM, EUI-SOO; COSTA, MARCIO SILVA; AGUIAR, TAMIRIS SAYURI; SCHROEDER, STEVEN; DO CARMO, ADRIANA SANTANA; CARVALHEIRO, ROBERTO; REZENDE NEVES, HAROLDO HENRIQUE; MOROZINI PADULA, ROMULO CLAUDIO; SUSSAI, THAYLA SOUZA; ZAVAREZ, LUDMILLA BALBO; CIPRIANO, RAFAEL SILVA; THEODORO CAMINHAS, MARIA MARGARETH; HAMBRECHT, GEORGE; COLLI, LICIA; EUFEMI, ELISA; AJMONE-MARSAN, PAOLO; CESANA, DENEB; SANNAZARO, MARCO; BUORA, MAURIZIO; MORGANTE, MICHELE; LIU, GEORGE; BICKHART, DEREK; VAN TASSELL, CURTIS PAUL; SOLKNER, JOHANN; SONSTEGARD, TAD STEWART; GARCIA, JOSE FERNANDO. A PLAG1 mutation contributed to stature recovery in modern cattle. SCIENTIFIC REPORTS, v. 7, DEC 7 2017. Web of Science Citations: 13.
UTSUNOMIYA, ADAM T. H.; SANTOS, DANIEL J. A.; BOISON, SOLOMON A.; UTSUNOMIYA, YURI T.; MILANESI, MARCO; BICKHART, DEREK M.; AJMONE-MARSAN, PAOLO; SOELKNER, JOHANN; GARCIA, JOSE F.; DA FONSECA, RICARDO; DA SILVA, MARCOS V. G. B. Revealing misassembled segments in the bovine reference genome by high resolution linkage disequilibrium scan. BMC Genomics, v. 17, SEP 5 2016. Web of Science Citations: 12.
O'BRIEN, ANA M. PEREZ; HOELER, DANIELA; BOISON, SOLOMON A.; MILANESI, MARCO; BOMBA, LORENZO; UTSUNOMIYA, YURI T.; CARVALHEIRO, ROBERTO; NEVES, HAROLDO H. R.; DA SILVA, MARCOS V. B.; VANTASSELL, CURTIS P.; SONSTEGARD, TAD S.; MESZAROS, GABOR; AJMONE-MARSAN, PAOLO; GARCIA, FERNANDO; SOELKNER, JOHANN. Low levels of taurine introgression in the current Brazilian Nelore and Gir indicine cattle populations. GENETICS SELECTION EVOLUTION, v. 47, APR 17 2015. Web of Science Citations: 12.
BOISON, S. A.; NEVES, H. H. R.; PEREZ O'BRIEN, A. M.; UTSUNOMIYA, Y. T.; CARVALHEIRO, R.; DA SILVA, M. V. G. B.; SOELKNER, J.; GARCIA, J. F. Imputation of non-genotyped individuals using genotyped progeny in Nellore, a Bos indicus cattle breed. LIVESTOCK SCIENCE, v. 166, n. SI, p. 176-189, AUG 2014. Web of Science Citations: 5.
O'BRIEN, ANA M. PEREZ; MESZAROS, GABOR; UTSUNOMIYA, YURI T.; SONSTEGARD, TAD S.; GARCIA, J. FERNANDO; VAN TASSELL, CURTIS P.; CARVALHEIRO, ROBERTO; DA SILVA, MARCOS V. B.; SOLKNER, JOHANN. Linkage disequilibrium levels in Bos indicus and Bos taurus cattle using medium and high density SNP chip data and different minor allele frequency distributions. LIVESTOCK SCIENCE, v. 166, n. SI, p. 121-132, AUG 2014. Web of Science Citations: 24.
O'BRIEN, ANA M. PEREZ; UTSUNOMIYA, YURI T.; MESZAROS, GABOR; BICKHART, DEREK M.; LIU, GEORGE E.; VAN TASSELL, CURTIS P.; SONSTEGARD, TAD S.; DA SILVA, MARCOS V. B.; GARCIA, JOSE FERNANDO; SOELKNER, JOHANN. Assessing signatures of selection through variation in linkage disequilibrium between taurine and indicine cattle. GENETICS SELECTION EVOLUTION, v. 46, MAR 4 2014. Web of Science Citations: 32.
NEVES, HAROLDO H. R.; CARVALHEIRO, ROBERTO; PEREZ O'BRIEN, ANA M.; UTSUNOMIYA, YURI T.; DO CARMO, ADRIANA S.; SCHENKEL, FLAVIO S.; SOELKNER, JOHANN; MCEWAN, JOHN C.; VAN TASSELL, CURTIS P.; COLE, JOHN B.; DA SILVA, MARCOS V. G. B.; QUEIROZ, SANDRA A.; SONSTEGARD, TAD S.; GARCIA, JOSE FERNANDO. Accuracy of genomic predictions in Bos indicus (Nellore) cattle. GENETICS SELECTION EVOLUTION, v. 46, FEB 27 2014. Web of Science Citations: 39.
UTSUNOMIYA, YURI T.; CARMO, ADRIANA S.; NEVES, HAROLDO H. R.; CARVALHEIRO, ROBERTO; MATOS, MARCIA C.; ZAVAREZ, LUDMILLA B.; ITO, PIER K. R. K.; O'BRIEN, ANA M. PEREZ; SOELKNER, JOHANN; PORTO-NETO, LAERCIO R.; SCHENKEL, FLAVIO S.; MCEWAN, JOHN; COLE, JOHN B.; DA SILVA, MARCOS V. G. B.; VAN TASSELL, CURTIS P.; SONSTEGARD, TAD S.; GARCIA, JOSE FERNANDO. Genome-Wide Mapping of Loci Explaining Variance in Scrotal Circumference in Nellore Cattle. PLoS One, v. 9, n. 2 FEB 18 2014. Web of Science Citations: 24.
PORTO-NETO, LAERCIO R.; SONSTEGARD, TAD S.; LIU, GEORGE E.; BICKHART, DEREK M.; DA SILVA, MARCOS V. B.; MACHADO, MARCO A.; UTSUNOMIYA, YURI T.; GARCIA, JOSE F.; GONDRO, CEDRIC; VAN TASSELL, CURTIS P. Genomic divergence of zebu and taurine cattle identified through high-density SNP genotyping. BMC Genomics, v. 14, DEC 13 2013. Web of Science Citations: 54.
UTSUNOMIYA, YURI T.; DO CARMO, ADRIANA S.; CARVALHEIRO, ROBERTO; NEVES, HAROLDO H. R.; MATOS, MARCIA C.; ZAVAREZ, LUDMILLA B.; O'BRIEN, ANA M. PEREZ; SOELKNER, JOHANN; MCEWAN, JOHN C.; COLE, JOHN B.; VAN TASSELL, CURTIS P.; SCHENKEL, FLAVIO S.; DA SILVA, MARCOS V. G. B.; PORTO NETO, LAERCIO R.; SONSTEGARD, TAD S.; GARCIA, JOSE F. Genome-wide association study for birth weight in Nellore cattle points to previously described orthologous genes affecting human and bovine height. BMC GENETICS, v. 14, JUN 13 2013. Web of Science Citations: 59.
UTSUNOMIYA, YURI TANI; O'BRIEN, ANA MARIA PEREZ; SONSTEGARD, TAD STEWART; VAN TASSELL, CURTIS PAUL; DO CARMO, ADRIANA SANTANA; MESZAROS, GABOR; SOELKNER, JOHANN; GARCIA, JOSE FERNANDO. Detecting Loci under Recent Positive Selection in Dairy and Beef Cattle by Combining Different Genome-Wide Scan Methods. PLoS One, v. 8, n. 5 MAY 16 2013. Web of Science Citations: 48.
BARBOSA‚ D.S.; MARANHÃO‚ R.C.; ARAÚJO‚ F.B.; CHANG‚ Y.H.; HIRATA‚ M.H.; ABDALLA‚ D.S.P. Sialic acid and oxidizability of low density lipoprotein subfractions of hyperlipidemic patients. CLINICAL BIOCHEMISTRY, v. 28, n. 4, p. 435-441, 1995.

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