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Seroepidemiological and molecular characterization of malarial infection in neotropical primates in the state of Maranhão

Grant number: 10/12820-4
Support type:Regular Research Grants
Duration: May 01, 2011 - April 30, 2014
Field of knowledge:Agronomical Sciences - Veterinary Medicine
Principal Investigator:Rosangela Zacarias Machado
Grantee:Rosangela Zacarias Machado
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
Assoc. researchers:Silvia Maria Fátima Di Santi

Abstract

This study aims to characterize the etiology, epidemiology and molecular simian malaria in the state of Maranhao through blood samples of primates in captivity and free living. Thus, the morphological observation of the parasite will be done by using traditional techniques recommended by the Health Ministry for diagnosis of human malaria in thick blood smears, which allows the specific differentiation of parasites and their stages of development in the peripheral blood, due high concentration parasitised erythrocytes in blood film, which allows better visualization of the structures of the parasite and the characteristic changes in the parasitized erythrocyte. For species-specific identification and quantification will be held, respectively, molecular techniques of PCR and qPCR. And we will evaluate the existence and frequency of antibodies anti-Plasmodium in free life and captive primates by indirect immunofluorescence assay (IFA). The project is licensed by IBAMA no. 23078-1 and it was approved by the Ethics Committee on Animal Use (CEUA) from Universidade Estadual Paulista Julio de Mesquita Filho, Jaboticabal, Protocol No. 020091/09. This project to intend to study the possible transmission of primate malaria to human and vice versa, and to diagnose the species of Plasmodium in primates as reservoirs in the state of Maranhão - Brazil. (AU)

Scientific publications (6)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PEREIRA FIGUEIREDO, MAYRA ARAGUAIA; DI SANTI, SILVIA MARIA; MANRIQUE, WILSON GOMEZ; ANDRE, MARCOS ROGERIO; MACHADO, ROSANGELA ZACARIAS. Serological and molecular techniques applied for identification of Plasmodium spp. in blood samples from nonhuman primates. Revista Brasileira de Parasitologia Veterinária, v. 27, n. 3, p. 363-376, JUL-SEP 2018. Web of Science Citations: 0.
PEREIRA FIGUEIREDO, MAYRA ARAGUAIA; DI SANTI, SILVIA MARIA; MANRIQUE, WILSON GOMEZ; ANDRE, MARCOS ROGERIO; MACHADO, ROSANGELA ZACARIAS. Identification of Plasmodium spp. in Neotropical primates of Maranhense Amazon in Northeast Brazil. PLoS One, v. 12, n. 8 AUG 10 2017. Web of Science Citations: 5.
PEREIRA FIGUEIREDO, MAYRA ARAGUAIA; DI SANTI, SILVIA MARIA; MANRIQUE, WILSON GOMEZ; GONCALVES, LUIZ RICARDO; ANDRE, MARCOS ROGERIO; MACHADO, ROSANGELA ZACARIAS. Molecular identification of Plasmodium spp. and blood meal sources of anophelines in environmental reserves on Sao LuIs Island, state of Maranhao, Brazil. PARASITES & VECTORS, v. 10, APR 26 2017. Web of Science Citations: 2.
BONATO, LETICIA; PEREIRA FIGUEIREDO, MAYRA ARAGUAIA; GONCALVES, LUIZ RICARDO; MACHADO, ROSANGELA ZACARIAS; ANDRE, MARCOS ROGERIO. Occurrence and molecular characterization of Bartonella spp. and hemoplasmas in neotropical primates from Brazilian Amazon. COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, v. 42, p. 15-20, OCT 2015. Web of Science Citations: 9.
PEREIRA FIGUEIREDO, MAYRA ARAGUAIA; FATIMA DI SANTI, SILVIA MARIA; PEREIRA FIGUEIREDO, THAYSA ARAGUAIA; MACHADO, ROSANGELA ZACARIAS. Natural Plasmodium infection in neotropical primates in the island of Sao Luis, state of Maranhao, Brazil. Revista Brasileira de Parasitologia Veterinária, v. 24, n. 2, p. 122-128, APR-JUN 2015. Web of Science Citations: 6.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.