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Adaptation for veterinary use of the type rabies antigen in adhered BHK cells used for humans

Grant number: 04/00575-4
Support type:Research Grants - Research Partnership for Technological Innovation - PITE
Duration: November 01, 2004 - March 31, 2007
Field of knowledge:Biological Sciences - Immunology - Applied Immunology
Principal researcher:Hisako Gondo Higashi
Grantee:Hisako Gondo Higashi
Home Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
Company: Ouro Fino Produtos Veterinários Ltda
City: São Paulo


The production and manufacture of vaccines against rabies for veterinary use using technology already developed for human use, of the type rabies antigen in adhered BHK cells, is aimed at increasing global productivity in response to new market demands. This involves a relevant technological innovation for the country, insofar as it will create the conditions for a significant increase in competitiveness in the biological products segment of the Brazilian veterinary market, tending to provoke a substantial drop in the price of these vaccines for the end consumer. This innovation will have a positive impact on public health, in addition to producing savings for the Ministry of Health, which is responsible for the vaccination of 19 million dogs in the entire country. The two institutions involved in this project are committed to the proof of concept of production and they should undertake every effort to achieve ideal levels of quality and efficiency of manufacture on an industrial scale and tests of the product in the field to comply with the necessary steps for the transference of this technology. (AU)

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