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Subsequent reproductive outcome in women who experienced a potentially life-threatening condition or a maternal near-miss during pregnancy


Objectives: To evaluate the long-term reproductive consequences affecting women who experienced potentially life-threatening or life-threatening (near-miss) maternal complications. Introduction: Although advances have been made towards maternal death reduction, little has been studied about long term repercussions of significant events such as severe maternal morbidity and maternal near-miss. These repercussions may be long-lasting, negatively affecting quality of life. Methods: In a retrospective cohort study, a total of 382 women who had had any potentially life-threatening pregnancy-related condition within the last five years were studied. A control group of 188 women who gave birth without complications was also included. Trained interviewers contacted the subjects by telephone and completed a pre-coded, structured questionnaire on reproductive health. Data were analyzed using odds ratios, adjusted for age. The main outcome measures were occurrence and outcome of subsequent pregnancies. Results: The estimated risk for women who experienced a maternal near miss becoming infertile as a result of tubal ligation or hysterectomy during index pregnancy was 3.5 times higher compared to controls in cases of severe maternal morbidity; however, no differences were found in the occurrence and number of subsequent pregnancies or perinatal outcome. Nonetheless, the risk of complication in subsequent pregnancies was five times greater in women who had experienced severe maternal morbidity. Conclusion: The occurrence of a potentially life-threatening or life-threatening maternal condition reduces future reproductive potential and increases the risk of complications in subsequent pregnancies. (AU)

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(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CAMARGO, RODRIGO S.; PACAGNELLA, RODOLFO C.; CECATTI, JOSE G.; PARPINELLI, MARY A.; SOUZA, JOAO P.; SOUSA, MARIA H. Subsequent reproductive outcome in women who have experienced a potentially life-threatening condition or a maternal near-miss during pregnancy. Clinics, v. 66, n. 8, p. 1367-1372, 2011. Web of Science Citations: 10.

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