| Grant number: | 11/15609-5 |
| Support Opportunities: | Regular Research Grants |
| Start date: | March 01, 2012 |
| End date: | February 28, 2014 |
| Field of knowledge: | Health Sciences - Medicine - Medical Clinics |
| Principal Investigator: | Samuel Katsuyuki Shinjo |
| Grantee: | Samuel Katsuyuki Shinjo |
| Host Institution: | Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil |
| Associated researchers: | Clovis Artur Almeida da Silva ; Daniel Brito de Araujo ; Edmund Chada Baracat ; Eloisa Silva Dutra de Oliveira Bonfá ; Fernando Henrique Carlos de Souza ; Helio Hehl Caiaffa Filho ; Lucas Yugo Shiguehara Yamakami ; Sandra Gofinet Pasoto ; Vilma dos Santos Trindade Viana |
Abstract
The idiopathic inflammatory myopathies (IIM) are a heterogeneous group of chronic autoimmune disease, systemic, associated with high morbidity and functional disability. Considering the clinical and histopathological features, the MII can be classified into polymyositis (PM), dermatomyositis (DM), juvenile dermatomyositis (JDM), inclusion body myositis (IBM), myositis associated with malignancy and myositis associated with other collagen diseases. The etiologies of both DM and PM remain unknown, but it is believed to be multifactorial, involving genetic, immunological and environmental features.Unlike other systemic autoimmune diseases, there are not studies analyzing specifically the gonadal function, cervical dysplasia and sexual dysfunction in patient with DM and PM, as well as their correlation with clinical and laboratory features and drug therapy. All these aspects will be analyzed in the present project. (AU)
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