Post-lesion cell regeneration in the nervous system and functional aspects of genes linked to innate immune response

• Grant number: 07/53732-8
• Support Opportunities: Research Grants - Young Investigators Grants
• Start date: November 01, 2008
• End date: May 31, 2013
• Field of knowledge: Biological Sciences - Biochemistry - Molecular Biology
• Principal Investigator: Isaias Glezer
• Grantee: Isaias Glezer
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated scholarship(s): 11/13134-0 - Study of the influence of signaling Toll-Like Receptors (TLRs) and the gene MyD88 on olfactry epithelium neuronal regeneration, BP.DD; 11/10680-3 - Functional identification of neuronal cells expressing CD36 receptor., BP.IC; 10/14043-5 - Caracterization of GEM gene expression in the signaling pathways of hypothalamus-pituitary-adrenal axis, BP.MS; 09/04437-9 - The Role of Innate Immune Response in the Course of Neuroregeneration: A Gene Expression Profile Study., BP.MS; 09/10358-4 - Characterization of CD36 Receptor Expression and Signaling in central nervous and olfactory system., BP.IC

Scientific publications

(7)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GLEZER, ISAIAS; RIVEST, SERGE. Oncostatin M is a novel glucocorticoid-dependent neuroinflammatory factor that enhances oligodendrocyte precursor cell activity in demyelinated sites. BRAIN BEHAVIOR AND IMMUNITY, v. 24, n. 5, SI, p. 695-704, JUL 2010. (07/53732-8)

CHANG, SEO YOUNG; GLEZER, ISAIAS. The balance between efficient anti-inflammatory treatment and neuronal regeneration in the olfactory epithelium. NEURAL REGENERATION RESEARCH, v. 13, n. 10, p. 1711-1714, OCT 2018. (13/07937-8, 07/53732-8)

CRISAFULLI, UMBERTO; XAVIER, ANDRE M.; DOS SANTOS, FABIANA B.; CAMBIAGHI, TAVANE D.; CHANG, SEO Y.; PORCIONATTO, MARIMELIA; CASTILHO, BEATRIZ A.; MALNIC, BETTINA; GLEZER, ISAIAS. Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium. FRONTIERS IN MOLECULAR NEUROSCIENCE, v. 11, MAR 6 2018. (09/04437-9, 07/53732-8, 16/24471-0, 11/13134-0, 09/52047-5, 13/07937-8)

XAVIER, ANDRE MACHADO; LUDWIG, RAISSA GUIMARAES; NAGAI, MAIRA HARUME; DE ALMEIDA, TIAGO JONAS; WATANABE, HEBE MIZUNO; HIRATA, MARCIO YUKIO; ROSENSTOCK, TATIANA ROSADO; PAPES, FABIO; MALNIC, BETTINA; GLEZER, ISAIAS. CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium. SCIENTIFIC REPORTS, v. 6, MAY 5 2016. (11/51604-8, 07/53732-8)

XAVIER, ANDRE MACHADO; OLIMPIO ANUNCIATO, APARECIDA KATARYNA; ROSENSTOCK, TATIANA ROSADO; GLEZER, ISAIAS. Gene Expression Control by Glucocorticoid Receptors during Innate Immune Responses. FRONTIERS IN ENDOCRINOLOGY, v. 7, APR 19 2016. (07/53732-8)

GLEZER, ISAIAS; BITTENCOURT, JACKSON C.; RIVEST, SERGE. Neuronal Expression of Cd36, Cd44, and Cd83 Antigen Transcripts Maps to Distinct and Specific Murine Brain Circuits. JOURNAL OF COMPARATIVE NEUROLOGY, v. 517, n. 6, p. 906-924, DEC 20 2009. (04/13849-5, 07/53732-8)

GLEZER, ISAIAS; RIVEST, SERGE. Oncostatin M is a novel glucocorticoid-dependent neuroinflammatory factor that enhances oligodendrocyte precursor cell activity in demyelinated sites. BRAIN BEHAVIOR AND IMMUNITY, v. 24, n. 5, p. 10-pg., 2010-07-01. (07/53732-8)