Study of nanoparticle-incorporated diamond-like carbon films for biomedical applications

• Grant number: 11/20345-7
• Support Opportunities: Research Grants - Young Investigators Grants
• Duration: June 01, 2012 - May 31, 2016
• Field of knowledge: Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials
• Principal Investigator: Fernanda Roberta Marciano
• Grantee: Fernanda Roberta Marciano
• Host Institution: Instituto de Pesquisa e Desenvolvimento (IP&D). Universidade do Vale do Paraíba (UNIVAP). São José dos Campos , SP, Brazil
• Associated researchers: Airton Abrahao Martin ; Anderson de Oliveira Lobo ; Cristina Pacheco Soares ; Evaldo Jose Corat ; Leandro José Raniero ; Newton Soares da Silva ; Vladimir Jesus Trava-Airoldi
• Associated scholarship(s): 16/00575-1 - Functional biomembranes based on peptides and bottlebrush polymers to tissue engineering, BE.PQ; 16/01184-6 - Bioactivity of nanostructured titanium surfaces, BP.IC; 14/11491-8 - Biomineralization study of diamond-like carbon films containing titanium dioxide nanoparticles, BP.IC; 13/20825-4 - Study of the growth of diamond-like carbon films containing incorporated titanium dioxide nanoparticles, BP.IC; 13/17415-9 - Electrochemical corrosion study of diamond-like carbon films containing crystalline diamond nanoparticles, BP.IC

Abstract

This project has an innovator and emergent character in biomedical area because presents a new technology to obtain nanoparticle-incorporated diamond-like carbon (DLC) films in order to cover orthopedic alloys. For that, this project proposes create a new research line (Biomedical Nanotechnology) in an institution with recognized tradition in Biomedical Engineering research (IP&D/Univap). The DLC films will be produced using plasma enhanced chemical vapor deposition technique. The nanoparticles of biomedical interest will be crystalline diamond (NCD), titanium dioxide and gold. The incorporation of these nanoparticles in DLC bulk was developed by the proponent of this Project during her doctoring degree. NCD and TiO2 will be functionalizated, and gold nanoparticles will be synthesized to homogeneously disperse in hydrocarbon liquids that are precursor DLC formation. Commercial biomedical alloys will be the substrates. The structural and morphological analysis will be performed by scanning electron microscopy, transmission electron microscopy, X-ray diffraction and Raman scattering spectroscopy. The films will be in vitro biologically characterizated using: (i) cell line like-L929 (ISSO 10993-5) and human osteoblast cells to evaluate cytotoxicity, cytocompatibility, bioactivity and biomineralization; (ii) bacterial strains to evaluate the bacteriostatic activity; and (iii) electrochemical assays to evaluate the anticorrosive effects using simulated body fluid, Ringer's solution and synovial solution. This project hopes prove the biocompatibility and anticorrosive effects in order to enable the use of DLC films in biomedical applications. (AU)

Scientific publications

(51)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SILVA SOARES, LUIS EDUARDO; NAHORNY, SIDNEI; BRAGA, VIVIAN DE FARIA; MARCIANO, FERNANDA ROBERTA; BHATTACHARJEE, TANMOY T.; LOBO, ANDERSON OLIVEIRA. Raman spectroscopy-multivariate analysis related to morphological surface features on nanomaterials applied for dentin coverage. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v. 228, MAR 5 2020. (11/20345-7, 11/17877-7, 16/00575-1, 13/11192-8, 14/21587-2, 15/09697-0, 14/02163-7)

MACHADO-PAULA, M. M.; CORAT, M. A. F.; LANCELLOTTI, M.; MI, G.; MARCIANO, F. R.; VEGA, M. L.; HIDALGO, A. A.; WEBSTER, T. J.; LOBO, A. O.. A comparison between electrospinning and rotary-jet spinning to produce PCL fibers with low bacteria colonization. Materials Science & Engineering C-Materials for Biological Applications, v. 111, JUN 2020. (11/20345-7, 15/08523-8, 11/17877-7, 14/50869-6, 14/16295-2, 15/09697-0)

SILVA SOARES, LUIS EDUARDO; MAGALHAES, JUAREZ DA SILVA; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA. Surface characteristics of a modified acidulated phosphate fluoride gel with nano-hydroxyapatite coating applied on bovine enamel subjected to an erosive environment. MICROSCOPY RESEARCH AND TECHNIQUE, v. 81, n. 12, p. 1456-1466, DEC 2018. (11/17877-7, 11/20345-7, 13/14464-9, 07/07984-5, 09/18440-1)

PESSOA, R. S.; DOS SANTOS, V. P.; CARDOSO, S. B.; DORIA, A. C. O. C.; FIGUEIRA, F. R.; RODRIGUES, B. V. M.; TESTONI, G. E.; FRAGA, M. A.; MARCIANO, F. R.; LOBO, A. O.; et al. TiO2 coatings via atomic layer deposition on polyurethane and polydimethylsiloxane substrates: Properties and effects on C. albicans growth and inactivation process. Applied Surface Science, v. 422, p. 73-84, NOV 15 2017. (11/50773-0, 12/15857-1, 11/17877-7, 11/20345-7, 15/10876-6, 15/09697-0, 15/08523-8, 16/00575-1, 15/05956-0)

SALLES, GEISA NOGUEIRA; DOS SANTOS PEREIRA, FERNANDA APARECIDA; PACHECO-SOARES, CRISTINA; MARCIANO, FERNANDA ROBERTA; HOLSCHER, CHRISTIAN; WEBSTER, THOMAS J.; LOBO, ANDERSON OLIVEIRA. A Novel Bioresorbable Device as a Controlled Release System for Protecting Cells from Oxidative Stress from Alzheimer's Disease. Molecular Neurobiology, v. 54, n. 9, p. 6827-6838, NOV 2017. (11/17877-7, 11/20345-7, 15/09697-0, 14/20561-0, 16/00575-1)

REIS DE VASCONCELLOS, LUANA MAROTTA; DO PRADO, RENATA FALCHETE; SARTORI, ELISA MATTIAS; SILVEIRA MENDONCA, DANIELA BACCELLI; MENDONCA, GUSTAVO; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA. In vitro osteogenesis process induced by hybrid nanohydroxyapatite/graphene nanoribbons composites. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, v. 30, n. 7, JUL 2019. (11/20345-7, 11/17877-7)

ZAMPRONI, LAURA N.; GRINET, MARCO A. V. M.; MUNDIM, MAYARA T. V. V.; REIS, MARCELLA B. C.; GALINDO, LAYLA T.; MARCIANO, FERNANDA R.; LOBO, ANDERSON O.; PORCIONATTO, MARIMELIA. Rotary jet-spun porous microfibers as scaffolds for stem cells delivery to central nervous system injury. Nanomedicine-Nanotechnology Biology and Medicine, v. 15, n. 1, p. 98-107, JAN 2019. (12/00652-5, 09/05700-5, 11/20345-7, 11/17877-7)

SANTANA-MELO, GABRIELA F.; RODRIGUES, BRUNO V. M.; DA SILVA, EDMUNDO; RICCI, RITCHELLI; MARCIANO, FERNANDA R.; WEBSTER, THOMAS J.; VASCONCELLOS, LUANA M. R.; LOBO, ANDERSON O.. Electrospun ultrathin PBAT/nHAp fibers influenced the in vitro and in vivo osteogenesis and improved the mechanical properties of neoformed bone. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 155, p. 544-552, JUL 1 2017. (11/17877-7, 11/20345-7, 15/09697-0, 15/08523-8, 16/00575-1)

NAHORNY, SIDNEI; ZANIN, HUDSON; CHRISTINO, VINIE ABREU; MARCIANO, FERNANDA ROBERTA; OLIVEIRA LOBO, ANDERSON; SILVA SOARES, LUIS EDUARDO. Multi-walled carbon nanotubes/graphene oxide hybrid and nanohydroxyapatite composite: A novel coating to prevent dentin erosion. Materials Science & Engineering C-Materials for Biological Applications, v. 79, p. 199-208, OCT 1 2017. (14/21587-2, 11/17877-7, 11/20345-7, 15/50093-0, 13/20825-4, 14/02163-7, 15/09697-0, 13/11192-8, 16/00575-1)

RICCI, RITCHELLI; LOBO, ANDERSON OLIVEIRA; MARCIANO, FERNANDA ROBERTA. In Vitro Osteogenesis Stimulation via Nano-Hydroxyapatite/Carbon Nanotube Thin Films on Biomedical Stainless Steel. MATERIALS, v. 11, n. 9, SEP 2018. (11/20345-7, 18/12383-5, 11/17877-7)

RODRIGUES, BRUNO V. M.; SILVA, ALINE S.; MELO, GABRIELA F. S.; VASCONSCELLOS, LUANA M. R.; MARCIANO, FERNANDA R.; LOBO, ANDERSON O.. Influence of low contents of superhydrophilic MWCNT on the properties and cell viability of electrospun poly (butylene adipate-co-terephthalate) fibers. Materials Science & Engineering C-Materials for Biological Applications, v. 59, p. 782-791, FEB 1 2016. (15/01259-3, 15/08523-8, 11/20345-7, 11/17877-7)

STOCCO, T. D.; RODRIGUES, B. V. M.; MARCIANO, F. R.; LOBO, A. O.. Design of a novel electrospinning setup for the fabrication of biomimetic scaffolds for meniscus tissue engineering applications. Materials Letters, v. 196, p. 221-224, JUN 1 2017. (11/17877-7, 15/08523-8, 11/20345-7, 16/00575-1, 15/09697-0)

ZANIN, H.; MARGRAF-FERREIRA, A.; DA SILVA, N. S.; MARCIANO, F. R.; CORAT, E. J.; LOBO, A. O.. Graphene and carbon nanotube composite enabling a new prospective treatment for trichomoniasis disease. Materials Science & Engineering C-Materials for Biological Applications, v. 41, p. 65-69, AUG 1 2014. (11/20345-7, 08/06654-4, 11/17877-7)

GRANATO, ALESSANDRO E. C.; RODRIGUES, BRUNO V. M.; RODRIGUES-JUNIOR, DORIVAL M.; MARCIANO, FERNANDA R.; LOBO, ANDERSON O.; PORCIONATTO, MARIMELIA A.. Magnetic super-hydrophilic carbon nanotubes/graphene oxide composite as nanocarriers of mesenchymal stem cells: Insights into the time and dose dependences. Materials Science & Engineering C-Materials for Biological Applications, v. 67, p. 694-701, OCT 1 2016. (11/20345-7, 12/00652-5, 15/08523-8, 11/17877-7)

GONCALVES, NATALIA I.; MUNCHOW, ELISEU A.; SANTOS, JESSICA D.; SATO, TABATA P.; DE OLIVEIRA, LETICIA R.; DE ARRUDA PAES-JUNIOR, TARCISIO J.; BOTTINO, MARCO C.; BORGES, ALEXANDRE L. S.. The role of polymeric nanofibers on the mechanical behavior of polymethyl methacrylate resin. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 112, DEC 2020. (11/17877-7, 11/20345-7)

SIQUEIRA, IDALIA A. W. B.; CORAT, MARCUS ALEXANDRE F.; CAVALCANTI, BRUNO DAS NEVES; RIBEIRO NETO, WILSON ALVES; MARTIN, AIRTON ABRAHAO; SUMAN BRETAS, ROSARIO ELIDA; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA. In Vitro and in Vivo Studies of Novel Poly(D,L-lactic acid), Superhydrophilic Carbon Nanotubes, and Nanohydroxyapatite Scaffolds for Bone Regeneration. ACS APPLIED MATERIALS & INTERFACES, v. 7, n. 18, p. 9385-9398, MAY 13 2015. (11/20345-7, 12/02159-4, 11/17877-7)

ZANIN, H.; ROSA, C. M. R.; ELIAZ, N.; MAY, P. W.; MARCIANO, F. R.; LOBO, A. O.. Assisted deposition of nano-hydroxyapatite onto exfoliated carbon nanotube oxide scaffolds. NANOSCALE, v. 7, n. 22, p. 10218-10232, 2015. (11/20345-7, 14/02163-7, 11/17877-7)

GRINET, MARCO A. V. M.; ZANIN, HUDSON; CAMPOS GRANATA, ALESSANDRO EUSTAQUIO; PORCIONATTO, MARIMELIA; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA. Fast preparation of free-standing nanohydroxyapatite-vertically aligned carbon nanotube scaffolds. JOURNAL OF MATERIALS CHEMISTRY B, v. 2, n. 9, p. 1196-1204, MAR 7 2014. (11/20345-7, 13/07696-0, 11/17877-7)

ALMEIDA, C. N.; RAMOS, B. C.; DA-SILVA, N. S.; PACHECO-SOARES, C.; TRAVA-AIROLDI, V. J.; LOBO, A. O.; MARCIANO, F. R.. Morphological analysis and cell viability on diamond-like carbon films containing nanocrystalline diamond particles. Applied Surface Science, v. 275, p. 258-263, JUN 15 2013. (11/20345-7, 11/17877-7)

BRAZIL, TAYRA RODRIGUES; DAS NEVES, MARCELE FLORENCIO; REGIANI, INACIO; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA. Proposed model for biomineralization of novel nanohydroxyapatite/vertically aligned multiwalled carbon nanotube scaffolds. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 16, n. 3, p. 661-667, MAY-JUN 2013. (11/20345-7, 12/02159-4, 11/17877-7)

WACHESK, C. C.; PIRES, C. A. F.; RAMOS, B. C.; TRAVA-AIROLDI, V. J.; LOBO, A. O.; PACHECO-SOARES, C.; MARCIANO, F. R.; DA-SILVA, N. S.. Cell viability and adhesion on diamond-like carbon films containing titanium dioxide nanoparticles. Applied Surface Science, v. 266, p. 176-181, FEB 1 2013. (11/20345-7, 11/17877-7)

COSTA, R. P. C.; LIMA-OLIVEIRA, D. A.; MARCIANO, F. R.; LOBO, A. O.; CORAT, E. J.; TRAVA-AIROLDI, V. J.. Comparative study of the tribological behavior under hybrid lubrication of diamond-like carbon films with different adhesion interfaces. Applied Surface Science, v. 285, n. B, p. 645-648, NOV 15 2013. (11/20345-7, 11/17877-7)

ZANIN, HUDSON; SAITO, EDUARDO; MARCIANO, FERNANDA ROBERTA; CERAGIOLI, HELDER JOSE; CAMPOS GRANATO, ALESSANDRO EUSTAQUIO; PORCIONATTO, MARIMELIA; LOBO, ANDERSON OLIVEIRA. Fast preparation of nano-hydroxyapatite/superhydrophilic reduced graphene oxide composites for bioactive applications. JOURNAL OF MATERIALS CHEMISTRY B, v. 1, n. 38, p. 4947-4955, 2013. (11/20345-7, 11/17877-7)

METOKI, N.; ROSA, C. M. R.; ZANIN, H.; MARCIANO, F. R.; ELIAZ, N.; LOBO, A. O.. Electrodeposition and biomineralization of nano-beta-tricalcium phosphate on graphenated carbon nanotubes. SURFACE & COATINGS TECHNOLOGY, v. 297, p. 51-57, JUL 15 2016. (11/20345-7, 11/17877-7)

ZANIN, HUDSON; MANZOLLI RODRIGUES, BRUNO VINICIUS; RIBEIRO NETO, WILSON ALVES; SUMAN BRETAS, ROSARIO ELIDA; DA-SILVA, NEWTON SOARES; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA. High loading of graphene oxide/multi-walled carbon nanotubes into PDLLA: A route towards the design of osteoconductive, bactericidal and non-immunogenic 3D porous scaffolds. Materials Chemistry and Physics, v. 177, p. 56-66, JUL 1 2016. (11/17877-7, 11/20345-7, 15/01259-3, 13/20054-8, 14/02163-7, 15/08523-8)

SIQUEIRA, IDALIA A. W. B.; OLIVEIRA, CILIANA A. G. S.; ZANIN, HUDSON; GRINET, MARCO A. V. M.; GRANATO, ALESSANDRO E. C.; PORCIONATTO, MARIMELIA A.; MARCIANO, FERNANDA R.; LOBO, ANDERSON O.. Bioactivity behaviour of nano-hydroxyapatite/freestanding aligned carbon nanotube oxide composite. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, v. 26, n. 2, FEB 2015. (11/20345-7, 14/02163-7, 13/07696-0, 11/17877-7)

ZANIN, H.; CERAGIOLI, H. J.; PETERLEVITZ, A. C.; BARANAUSKAS, VITOR; MARCIANO, F. R.; LOBO, A. O.. Field emission properties of the graphenated carbon nanotube electrode. Applied Surface Science, v. 324, p. 174-178, JAN 1 2015. (11/20345-7, 14/02163-7, 11/17877-7)

RAMOS, B. C.; SAITO, E.; TRAVA-AIROLDI, V. J.; LOBO, A. O.; MARCIANO, F. R.. Diamond-like carbon electrochemical corrosion resistance by addition of nanocrystalline diamond particles for biomedical applications. SURFACE & COATINGS TECHNOLOGY, v. 259, n. C, p. 732-736, NOV 25 2014. (11/20345-7, 11/17877-7)

LOBO, ANDERSON O.; ZANIN, HUDSON; SIQUEIRA, IDALIA A. W. B.; LEITE, NELLY C. S.; MARCIANO, FERNANDA R.; CORAT, EVALDO J.. Effect of ultrasound irradiation on the production of nHAp/MWCNT nanocomposites. Materials Science & Engineering C-Materials for Biological Applications, v. 33, n. 7, p. 4305-4312, OCT 1 2013. (11/20345-7, 11/17877-7)

LOBO, ANDERSON OLIVEIRA; SIQUEIRA, IDALIA A. W. B.; DAS NEVES, MARCELE F.; MARCIANO, FERNANDA ROBERTA; CORAT, EVALDO JOSE; CORAT, MARCUS ALEXANDRE F.. In vitro and in vivo studies of a novel nanohydroxyapatite/superhydrophilic vertically aligned carbon nanotube nanocomposites. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, v. 24, n. 7, p. 1723-1732, JUL 2013. (11/20345-7, 11/17877-7)

BARBOSA, MICHELLE C.; MESSMER, NIGEL R.; BRAZIL, TAYRA R.; MARCIANO, FERNANDA R.; LOBO, ANDERSON O.. The effect of ultrasonic irradiation on the crystallinity of nano-hydroxyapatite produced via the wet chemical method. Materials Science & Engineering C-Materials for Biological Applications, v. 33, n. 5, p. 2620-2625, JUL 1 2013. (11/20345-7, 11/17877-7)

NEVES, MARCELE FLORENCIO; SILVA, GISLENE RODRIGUES; BRAZIL, TAYRA RODRIGUES; MARCIANO, FERNANDA ROBERTA; PACHECO-SOARES, CRISTINA; LOBO, ANDERSON OLIVEIRA. Calcification in vitro of biomineralizated nanohydroxyapatite/superydrophilic vertically aligned multiwalled carbon nanotube scaffolds. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 16, n. 3, p. 614-618, MAY-JUN 2013. (11/20345-7, 12/02159-4, 11/17877-7)

NEVES, MARCELE FLORENCIO; BRAZIL, TAYRA RODRIGUES; SILVA SOARES, LUIS EDUARDO; CORAT, EVALDO JOSE; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA. In vitro biomineralization of a novel hydroxyapatite/superhydrophilic multiwalled carbon nanotube nanocomposite using simulated body fluids. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 16, n. 3, p. 650-654, MAY-JUN 2013. (11/20345-7, 12/02159-4, 11/17877-7)

ANTONIOLI, ELIANE; LOBO, ANDERSON O.; FERRETTI, MARIO; COHEN, MOISES; MARCIANO, FERNANDA R.; CORAT, EVALDO J.; TRAVA-AIROLDI, VLADIMIR J.. An evaluation of chondrocyte morphology and gene expression on superhydrophilic vertically-aligned multi-walled carbon nanotube films. Materials Science & Engineering C-Materials for Biological Applications, v. 33, n. 2, p. 641-647, MAR 1 2013. (11/20345-7, 11/17877-7)

MACHADO, SUSANE MOREIRA; PACHECO-SOARES, CRISTINA; MARCIANO, FERNANDA ROBERTA; LOBO, ANDERSON OLIVEIRA; DA SILVA, NEWTON SOARES. Photodynamic therapy in the cattle protozoan Tritrichomonas foetus cultivated on superhydrophilic carbon nanotube. Materials Science & Engineering C-Materials for Biological Applications, v. 36, p. 180-186, MAR 1 2014. (11/20345-7, 08/06654-4, 11/17877-7)

OLIVEIRA, C. A. G. S.; STEIN, M. F.; SAITO, E.; ZANIN, H.; VIEIRA, L. S.; RANIERO, L.; TRAVA-AIROLDI, V. J.; LOBO, A. O.; MARCIANO, F. R.. Effect of gold oxide incorporation on electrochemical corrosion resistance of diamond-like carbon. DIAMOND AND RELATED MATERIALS, v. 53, p. 40-44, MAR 2015. (11/20345-7, 14/02163-7, 11/17877-7)

SAITO, E.; ANTUNES, E. F.; ZANIN, H.; MARCIANO, F. R.; LOBO, A. O.; TRAVA-AIROLDI, V. J.; CORAT, E. J.. Oxygen Plasma Exfoliated Vertically-Aligned Carbon Nanotubes as Electrodes for Ultrasensitive Stripping Detection of Pb2+. Journal of the Electrochemical Society, v. 161, n. 5, p. H321-H325, 2014. (11/20345-7, 11/17877-7)

MACHADO, M. M.; LOBO, A. O.; MARCIANO, F. R.; CORAT, E. J.; CORAT, M. A. F.. Analysis of cellular adhesion on superhydrophobic and superhydrophilic vertically aligned carbon nanotube scaffolds. Materials Science & Engineering C-Materials for Biological Applications, v. 48, p. 365-371, MAR 1 2015. (11/20345-7, 11/17877-7)

RODRIGUES, BRUNO V. M.; LEITE, NELLY C. S.; CAVALCANTI, BRUNO DAS NEVES; DA SILVA, NEWTON S.; MARCIANO, FERNANDA R.; CORAT, EVALDO J.; WEBSTER, THOMAS J.; LOBO, ANDERSON O.. Graphene oxide/multi-walled carbon nanotubes as nanofeatured scaffolds for the assisted deposition of nanohydroxyapatite: characterization and biological evaluation. INTERNATIONAL JOURNAL OF NANOMEDICINE, v. 11, p. 2569-2585, 2016. (11/20345-7, 15/08523-8, 13/20054-8, 11/17877-7)

WACHESK, C. C.; TRAVA-AIROLDI, V. J.; DA-SILVA, N. S.; LOBO, A. O.; MARCIANO, F. R.. The Influence of Titanium Dioxide on Diamond-Like Carbon Biocompatibility for Dental Applications. Journal of Nanomaterials, 2016. (11/20345-7, 13/20054-8, 12/15857-1, 11/17877-7)

DE CASTRO, JUCARA G.; RODRIGUES, BRUNO V. M.; RICCI, RITCHELLI; COSTA, MAIRA M.; RIBEIRO, ANDRE F. C.; MARCIANO, FERNANDA R.; LOBO, ANDERSON O.. Designing a novel nanocomposite for bone tissue engineering using electrospun conductive PBAT/polypyrrole as a scaffold to direct nanohydroxyapatite electrodeposition. RSC ADVANCES, v. 6, n. 39, p. 32615-32623, 2016. (11/20345-7, 15/08523-8, 11/17877-7)

ZOGBI, JR., M. M.; SAITO, E.; ZANIN, H.; MARCIANO, F. R.; LOBO, A. O.. Hydrothermal-electrochemical synthesis of nano-hydroxyapatite crystals on superhydrophilic vertically aligned carbon nanotubes. Materials Letters, v. 132, p. 70-74, OCT 1 2014. (11/20345-7, 12/15773-2, 11/17877-7)

RICCI, R.; LEITE, N. C. S.; DA-SILVA, N. S.; PACHECO-SOARES, C.; CANEVARI, R. A.; MARCIANO, F. R.; WEBSTER, T. J.; LOBO, A. O.. Graphene oxide nanoribbons as nanomaterial for bone regeneration: Effects on cytotoxicity, gene expression and bactericidal effect. Materials Science & Engineering C-Materials for Biological Applications, v. 78, p. 341-348, SEP 1 2017. (11/17877-7, 11/20345-7, 13/14464-9, 13/20054-8, 15/09697-0, 09/18440-1, 16/00575-1)

TONIATTO, T. V.; RODRIGUES, B. V. M.; MARSI, T. C. O.; RICCI, R.; MARCIANO, F. R.; WEBSTER, T. J.; LOBO, A. O.. Nanostructured poly (lactic acid) electrospun fiber with high loadings of TiO2 nanoparticles: Insights into bactericidal activity and cell viability. Materials Science & Engineering C-Materials for Biological Applications, v. 71, p. 381-385, FEB 1 2017. (11/17877-7, 15/08523-8, 13/08341-1, 11/20345-7, 14/16966-4)

SILVA, EDMUNDO; REIS DE VASCONCELLOS, LUANA MAROTTA; RODRIGUES, BRUNO V. M.; DOS SANTOS, DANILO MARTINS; CAMPANA-FILHO, SERGIO P.; MARCIANO, FERNANDA ROBERTA; WEBSTER, THOMAS J.; LOBO, ANDERSON OLIVEIRA. PDLLA honeycomb-like scaffolds with a high loading of superhydrophilic graphene/multi-walled carbon nanotubes promote osteoblast in vitro functions and guided in vivo bone regeneration. Materials Science & Engineering C-Materials for Biological Applications, v. 73, p. 31-39, APR 1 2017. (11/17877-7, 11/20345-7, 15/09697-0, 15/08523-8, 16/00575-1)

PEREIRA, F. A. S.; SALLES, G. N.; RODRIGUES, B. V. M.; MARCIANO, F. R.; PACHECO-SOARES, C.; LOBO, A. O.. Diamond nanoparticles into poly(lactic acid) electrospun fibers: Cytocompatible and bioactive scaffolds with enhanced wettability and cell adhesion. Materials Letters, v. 183, p. 420-424, NOV 15 2016. (11/20345-7, 14/20561-0, 15/08523-8, 11/17877-7)

LOPES, F. S.; OLIVEIRA, J. R.; MILANI, J.; OLIVEIRA, L. D.; MACHADO, J. P. B.; TRAVA-AIROLDI, V. J.; LOBO, A. O.; MARCIANO, F. R.. Biomineralized diamond-like carbon films with incorporated titanium dioxide nanoparticles improved bioactivity properties and reduced biofilm formation. Materials Science & Engineering C-Materials for Biological Applications, v. 81, p. 373-379, DEC 1 2017. (12/15857-1, 11/17877-7, 11/20345-7, 14/11491-8, 15/09697-0, 16/00575-1)

WACHESK, C. C.; SEABRA, S. H.; DOS SANTOS, T. A. T.; TRAVA-AIROLDI, V. J.; LOBO, A. O.; MARCIANO, F. R.. In vivo biocompatibility of diamond-like carbon films containing TiO2 nanoparticles for biomedical applications. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, v. 32, n. 9, SEP 2021. (11/20345-7, 12/15857-1)

DIAS, VANESSA; MACIEL, HOMERO; FRAGA, MARIANA; LOBO, ANDERSON O.; PESSOA, RODRIGO; MARCIANO, FERNANDA R.. Atomic Layer Deposited TiO2 and Al2O3 Thin Films as Coatings for Aluminum Food Packaging Application. MATERIALS, v. 12, n. 4, FEB 2 2019. (14/18139-8, 11/50773-0, 11/17877-7, 12/15857-1, 11/20345-7, 16/00575-1, 15/05956-0, 15/09697-0, 18/01265-1, 15/10876-6)

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