Calorimetry researcher visiting

• Grant number: 11/17643-6
• Support Opportunities: Research Grants - Visiting Researcher Grant - International
• Duration: September 22, 2011 - November 21, 2011
• Field of knowledge: Biological Sciences - Biochemistry - Chemistry of Macromolecules
• Principal Investigator: Carlos Henrique Inacio Ramos
• Grantee: Carlos Henrique Inacio Ramos
• Visiting researcher: Conceição A. Minetti
• Visiting researcher institution: Rutgers The State University of New Jersey, New Brunswick, United States
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

The coordinator of this proposal, Carlos Ramos, has a research project financed by FAPESP, which has as its objective the use of the technique of isothermal titration calorimetry (ITC) to study the interaction between proteins and small molecules. The proteins studied in the research group are those involved in protein homeostasis, especially molecular chaperones and sirtuins. With the great experience prof Minetti has in the area of study of thermodynamics of interaction between proteins and ligands, she can make important contributions in our research project and training of specialized personnel. In addition to that, an automated ITC will be installed in an Institutional Laboratory at UNICAMP and will be available to researchers of universities in Sao Paulo state. Thus the training of specialized personnel will be very important to the widespread use of this equipment. (AU)