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In situ evaluation of the effect of the CO2 laser, associated or not to fluoride, in inhibiting bovine enamel erosion progression

Grant number: 12/17170-3
Support type:Regular Research Grants
Duration: May 01, 2013 - April 30, 2015
Field of knowledge:Health Sciences - Dentistry
Principal Investigator:Patricia Moreira de Freitas Costa e Silva
Grantee:Patricia Moreira de Freitas Costa e Silva
Home Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Epidemiological studies indicate an increase in the prevalence of dental erosion due to an increased longevity of the population and changes in dietary habits of the population, which has indiscriminately consuming acidic foods and drinks. Thus, this study aims to evaluate the efficacy of CO2 laser irradiation, associated or not to fluoride, on protecting eroded bovine dental enamel from future acids episodes. Sixteen volunteers will participate in this in situ study which five treatments will be tested: G1 - control (no treatment), G2 - topical fluoride application (Acidulated Phosphate Fluoride - APF), G3 - CO2 laser irradiation (10.6 ¼ m ) G4 - CO2 laser (10.6 ¼ m) + topical application of FFA and G5 - topical application of APF + CO2 laser. The samples will have their microhardness (n = 13) measured at the start of the trial period (baseline, t0) and after the erosive challenge in vitro (t1), which will be accomplished by immersing the samples in the citric acid solution 1% (pH 4.0) for 3 minutes, after the enamel surface treatments eroded in vitro (t2) and in situ after erosion (t3), which will be performed by immersing the device in the samples containing palatal citric acid (0.05M - pH 2.3) for 20 minutes, 2 times daily. The scanning electron microscopy (n = 3) will allow the observation of changes in surface morphology in 04 experimental times. The results will be evaluated according to the classical statistical concepts. (AU)

Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MANTILLA, TAIS FONSECA; DA SILVA, CAMILA VIEIRA; RAMOS-OLIVEIRA, THAYANNE MONTEIRO; TURSSI, CECILIA PEDROSO; RIBEIRO, MARTHA SIMOES; DE FREITAS, PATRICIA MOREIRA. TiF4 gel effects on tubular occlusion of eroded/abraded human dentin. MICROSCOPY RESEARCH AND TECHNIQUE, v. 80, n. 11, p. 1182-1188, NOV 2017. Web of Science Citations: 1.
MANTILLA, TAIS FONSECA; RAMOS-OLIVEIRA, THAYANNE MONTEIRO; DA SILVA, CAMILA VIEIRA; PEREIRA CERSOSIMO, MARIA CECILIA; TURSSI, CECILIA PEDROSO; DE FREITAS, PATRICIA MOREIRA. Effects of Different Concentrations and Excipients of Titanium Tetrafluoride on Dentin Erosion Prevention. ORAL HEALTH & PREVENTIVE DENTISTRY, v. 15, n. 5, p. 461-465, OCT 13 2017. Web of Science Citations: 1.
THAYANNE MONTEIRO RAMOS-OLIVEIRA; CAMILA VIEIRA SILVA; PAULA MENDES ACATAUASSU NUNES; CECÍLIA PEDROSO TURSSI; PETER RECHMANN; PATRICIA MOREIRA DE FREITAS. AmF/NaF/SnCl2 solution reduces in situ enamel erosion – profilometry and cross-sectional nanoindentation analysis. Brazilian Oral Research, v. 31, p. -, 2017.
RAMOS-OLIVEIRA, THAYANNE MONTEIRO; SILVA, CAMILA VIEIRA; ACATAUASSU NUNES, PAULA MENDES; TURSSI, CECLIA PEDROSO; RECHMANN, PETER; DE FREITAS, PATRICIA MOREIRA. AmF/NaF/SnCl2 solution reduces in situ enamel erosion - profilometry and cross-sectional nanoindentation analysis. Brazilian Oral Research, v. 31, 2017. Web of Science Citations: 3.

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