Advanced search
Start date
Betweenand

CRID - Center for Research in Inflammatory Diseases

Grant number: 13/08216-2
Support Opportunities:Research Grants - Research, Innovation and Dissemination Centers - RIDC
Duration: August 01, 2013 - July 31, 2025
Field of knowledge:Biological Sciences - Pharmacology
Principal Investigator:Fernando de Queiroz Cunha
Grantee:Fernando de Queiroz Cunha
Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Pesquisadores principais:
( Atuais )
Helder Takashi Imoto Nakaya ; João Santana da Silva ; José Carlos Farias Alves Filho ; Paulo Louzada Junior ; Rita de Cassia Aleixo Tostes Passaglia ; Thiago Mattar Cunha
Pesquisadores principais:
( Anteriores )
Carlos Henrique Tomich de Paula da Silva ; Dario Simões Zamboni
Associated researchers:Ana Maria Ferreira Roselino ; Ana Paula de Carvalho Panzeri Carlotti ; Anibal Basile Filho ; Antônio Pazin Filho ; Beatriz Rossetti Ferreira ; Cacilda da Silva Souza ; Carlos Henrique Tomich de Paula da Silva ; Claudio Miguel da Costa Neto ; Dario Simões Zamboni ; Doralina Guimarães Brum Souza ; Eduardo Antônio Donadi ; Eduardo Barbosa Coelho ; Elcio dos Santos Oliveira Vianna ; Flavio da Silva Emery ; Francisco José Albuquerque de Paula ; Geraldo Aleixo da Silva Passos Júnior ; Helder Takashi Imoto Nakaya ; João Santana da Silva ; José Carlos Farias Alves Filho ; Jose Marcos Chaves Ribeiro ; Luiz Osório Silveira Leiria ; Marcello Henrique Nogueira Barbosa ; Marcos Antonio Rossi ; Marcos de Carvalho Borges ; Renê Donizeti Ribeiro de Oliveira ; Ronaldo de Albuquerque Ribeiro ; Roque Pacheco de Almeida ; Sandra Yasuyo Fukada Alves ; Sérgio Henrique Ferreira ; Thiago Mattar Cunha ; Vanessa Carregaro Pereira ; Vânia Luiza Deperon Bonato ; Virginia Paes Leme Ferriani ; Waldiceu Aparecido Verri Junior
Associated grant(s):23/09798-7 - Experimental protocols consolidation using human pathogenic fungi in the Bi-Institutional Platform for Research in Translational Medicine., AV.BR
23/01533-4 - CGRP and PKM2 immunomodulation during cutaneous leishmaniasis infection, AP.R
22/11885-2 - Identification of critical cellular factors during neurotropic arbovirus infection through global screening with CRISPR-Cas9 libraries, AV.BR
+ associated grants 22/08412-5 - Understanding the molecular regulation of Th17 and regulatory T cells in infections and autoimmune diseases, AP.R
21/08865-7 - Multi-user equipment approved in grant 2013/08216-2: QuantStudio 5 Real Time PCR System Applied Biosystems, AP.EMU
20/05211-3 - Evaluation of Amphiregulin as a prognostic biomarker of severity and its participation in the pathophysiology of COVID-19, AP.R
20/04860-8 - Global genome screening with CRISPRko libraries to identify essential factors in SARS-CoV2 infection and replication, AP.R
20/05601-6 - Neutrophil extracelular traps (NETs): role in the pathophysiology and potential as a therapeutic target on COVID-19, AP.R
19/21482-0 - Multi-User Equipment approved in grant 2013/08216-2: chromium" 10x genomics, controller & accessory kit, 12 mo. warranty, AP.EMU
19/08265-0 - Multi-User Equipment approved in grant 2013/08216-2: analyzer measures oxygen consumption rate, AP.EMU
18/15235-7 - Macrophage metabolism as a target for cancer therapy, AP.R SPRINT
18/15192-6 - Contribution of endothelial dysfunction in progression of aortic aneurysm, AP.R SPRINT
17/23826-2 - Rheumatoid arthritis and periodontal disease: association between microbiome and disease-modifying drugs, AV.BR
17/20347-6 - Multi-user equipment approved in grant 13/08216-2: flow cytometer, AP.EMU
17/10255-7 - Molecular mechanisms underlying the resistance to the immunosupression development in neonatal sepsis, AV.EXT
15/01055-9 - Multi-User Equipment approved in grant 2013/08216-2: sistema de alta performance por imagem, AP.EMU
14/50268-2 - Deciphering the interactions between Legionella longbeachae and eukaryotic host cells, AP.R - associated grants
Associated scholarship(s):24/10752-4 - HDL-mediated reverse cholesterol transport as a regulator of hepatic lipogenesis, BP.PD
24/10526-4 - Metabolic changes in lymphocytes in the face of viral infection, BP.TT
24/06707-3 - Assessment of immunocompetence and risk factors of infection in patients with systemic lupus erythematosus, BP.IC
+ associated scholarships 24/03237-6 - Regulation between AIM2/BLIMP-1 in the activation of dendritic cells during in vitro and in vivo L. infantum infection., BP.IC
24/08618-8 - Single-cell transcriptomes of inflammatory diseases, BP.TT
24/08622-5 - Role of HCAR2 receptor in the development of neuropathic pain, BP.IC
24/04906-9 - Mechanisms and consequences of the activation of cytoplasmic receptors by intracellular pathogens, BP.TT
24/01270-6 - Modulation of the immune response to Cryptococcus neoformans by IL-27 and IL-35, BP.IC
23/13328-6 - Role of the enzyme Pyruvate Kinase M2 (PKM2) in astrocytes under neuroinflammatory conditions, BP.DR
24/02507-0 - HDL-mediated reverse transport as a regulator of hepatic lipogenesis, BP.TT
23/16352-5 - EVALUATION OF THE RELEASE OF NEUTROPHIL EXTRACELLULAR NETWORKS (NETs) IN RESPONSE TO DIFFERENT VARIANTS OF THE SARS-CoV-2 VIRUS, BP.IC
23/09528-0 - Study of the mechanisms involved in the reduction of endothelin-1 signaling in the vascular bed of spontaneously diabetic mice, BP.MS
23/13452-9 - Systems Biology Applied to Transcriptomic Analysis of Inflammatory Diseases, BP.PD
23/05350-1 - Maternal transfer of antibodies and BAT development, BP.PD
23/11522-0 - Scientific dissemination contextualized in health sciences., BP.TT
23/08211-2 - In vitro and in vivo validation of new pharmacology HITs for the treatment of inflammatory diseases and neuropathic pain, BP.PD
23/02994-5 - Systems immunology of autoimmune inflammatory diseases, BP.DD
23/06703-5 - Manipulation and genotyping of Cre-lox transgenic animals, BP.TT
23/06526-6 - Training in laboratory and colony management of transgenic mice., BP.TT
22/16903-9 - Role of neutrophil extracellular traps in the pathogenesis of inflammatory bowel disease, BP.DR
22/16347-9 - Characterization of the autoimmune response in mice deficient for the DDX41 protein on regulatory T cells., BP.MS
23/02455-7 - Contextualized scientific dissemination in health education, BP.TT
23/04175-1 - Technical training in autoimmune neurodegenerative diseases, BP.TT
23/03043-4 - Single-cell transcriptomes of inflammatory diseases, BP.PD
23/01133-6 - Characterization and structural optimization of protein target ligands related to inflammatory processes studied by CRID, BP.PD
22/13361-0 - Influence of the metabolic profile of CD4+ T cells on testosterone-induced heart dysfunction in an experimental model of gender affirming hormone therapy, BP.DR
23/00472-1 - Mechanisms and consequences of activation of cytoplasmic receptors by intracellular pathogens., BP.TT
22/13842-9 - Bipolar Affective Disorder: a transcriptome data study, BP.IC
22/15620-3 - Mechanisms involved in Neutrophil Extracellular Traps (NETs) during infectious and inflammatory diseases, BP.PD
22/04864-9 - Systems Immunology of Inflammatory Diseases, BP.MS
22/14416-3 - Generation and genotyping of transgenic animals (Cre-lox System) for experimental models, BP.TT
22/10198-1 - Learning of procedures for obtaining mouse embryos., BP.TT
22/09144-4 - Implementation, experimental standardization and analysis of multiparametric flow cytometry, BP.TT
22/02651-8 - The importance of STING signaling pathway on the differentiation and function of T regulatory cells, BP.DD
22/08052-9 - Participation of NETs as a biomarker of autoimmune rheumatic diseases, BP.PD
21/10494-7 - Importance of IL-33 in the development of Wallerian degeneration and its actions on immune cells, BP.DR
22/05647-1 - Genotyping of conditionally deficient animals using the Cre/loxP system, BP.TT
22/04846-0 - Contribution of endothelin-1 in perivascular adipose tissue dysfunction in obese mice: involvement of transcriptional factor Nrf2 and kinase GSK-3B, BP.IC
22/02605-6 - Systems Biology Applied to Transcriptomic Analysis of Inflammatory Diseases, BP.PD
21/00840-5 - Cellular and molecular characterization and origin of the leukocytes accumulated in the leptomeninges of the dorsal roots of neuropathic animals, BP.PD
22/04449-1 - The importance of iron metabolism in the differentiation, stability, function and pathogenicity of Th17 lymphocytes and its implication in autoimmunity, BP.PD
22/00951-4 - Scientific diffusion contextualized in health sciences, BP.TT
21/09854-9 - Role of cytoplasmic DNA sensor, STING, in cisplatin-induced peripheral neuropathic pain development, BP.DR
21/08847-9 - Contribution of autophagic processes in perivascular adipose tissue hyperinflammation associated with metabolic syndrome, BP.PD
21/13400-3 - Manipulation and genotyping of transgenic animal Cre-lox, BP.TT
21/11728-1 - Generation and genotyping of transgenic animals (Cre-Lox System) for use in experimental models, BP.TT
21/08843-3 - The role of gamma delta T cells in the acute Sepsis, BP.IC
21/10650-9 - Morphological and functional characterization of sensory neurons expressing neurotensin (NTS), BP.IC
21/08754-0 - Importance of NFR2 on osteoclastogenis and its impact on bone metabolism, BP.PD
21/06771-5 - Characterization of resistance and susceptibility genes in Visceral Leishmaniasis, BP.PD
21/08330-6 - Crosstalk between innate immune cells and thermogenic adipocytes in the regulation of energetic metabolism, BP.PD
21/08425-7 - Immunopathogenesis of post-Sepsis immunosuppression, BP.PD
21/08434-6 - Identification and validation of drugs for the treatment of Leishmaniasis, BP.PD
20/11339-2 - Trimethylamine N-oxide (TMAO) as a link among gut dysbiosis, immune system activation and vascular dysfunction induced by ethanol consumption, BP.PD
21/03506-9 - Contextualized scientific dissemination in health education, BP.TT
21/04378-4 - ROLE OF O-GLUCONACILATION IN THE ACTIVITY OF THE FOXO1 TRANSCRIPTION FACTOR: VASCULAR ENDOTHELIAL CELL PHYSIOLOGY IN HYPERGLYCEMIA, BP.IC
21/02049-3 - DDX41 protein study on the differentiation and function of regulatory T cells (Tregs), BP.IC
21/03525-3 - Tissue processing for histopathological analysis in experimental models., BP.TT
21/03420-7 - Role of kinase inhibition of G 2 protein-coupled receptors (GRK2) in the treatment of Sepsis, BP.IC
21/02047-0 - Determination of the metabolic profile in real time of cells of the immune system, BP.TT
21/02934-7 - Gene knokouts generation and validation using CRISPR/Cas9 in vitro, BP.TT
21/01213-4 - Identification of therapeutic targets from transcriptomic analysis of the sensory system cells after peripheral nerve injury, BP.IC
21/00696-1 - Manipulation and genotyping of transgenic animal expressing human ACE2 for COVID-19 studies, BP.TT
21/02053-0 - Evaluation of leishmanicidal activity of drugs in macrophages infected by L. amazonensis, BP.TT
20/11372-0 - Importance of ERK5 in the differentiation and function of regulatory T cells, BP.DR
19/24921-4 - Role of resistin via CAP1 in perivascular adipose tissue and vascular dysfunction in an experimental Arthritis model, BP.DR
20/13742-9 - Structural studies and molecular screening for the development of PKM2 and related proteins inhibitors, BP.PD
20/05446-0 - Origin, dynamics and transcriptional profile of dorsal root ganglion and sciatic nerve macrophages in homeostasis and during neuropathic pain, BP.DD
20/08109-5 - Molecular mechanisms involved in the desensibilization of ± adrenergic receptors during Sepsis: potential for the treatment of Vasoplegia, BP.PD
19/20692-0 - Involvement of the NLRP3 inflammasome in cardiac dysfunction associated with supraphysiological levels of testosterone, BP.DR
18/17542-4 - The role of the STING signaling pathway in the regulation of Th17 cell pathogenicity and its implication for autoimmunity, BP.DR
20/04170-1 - The role of DDX41 on the differentiation and function of regulatory T lymphocytes, BP.DR
20/02642-3 - Characterization of the TIGIT+ T regulatory cell subset in response to therapy with disease-modifying anti-rheumatic drugs in patients with Rheumatoid Arthritis, BP.PD
20/00382-4 - Sting signaling pathway study on the differentiation and function of Regulatory T cells (Tregs), BP.IC
19/15070-0 - Determination of molecular and cellular mechanisms associated with Sepsis outcome using single cell RNA sequencing, BP.DR
20/02899-4 - Role of NETs in the pathogenesis of psoriasis, BP.TT
20/04393-0 - The use of High-content to evaluate the leishmanicidal activity of drugs., BP.TT
19/25305-5 - Involvement of O-GlcNAcylation in astrocyte activation during development of experimental autoimmune encephalomyelitis, BP.IC
19/19190-0 - Role of NETs as osteoclastogenesis modulators in Rheumatoid Arthritis , BP.DR
19/22579-7 - Systems biology applied to transcriptomic analysis of inflammatory diseases, BP.PD
19/25622-0 - Generation and genotyping of transgenic animals (Cre-Lox system) for use in experimental models, BP.TT
19/25586-4 - Contribution of tyrosin phosfatase protein DUSP1 in endothelial disfunction induced by lysophosfatidilcolina and participation in the formation of atherosclerosis plaque, BP.IC
19/15063-4 - Characterization of the role of the sensory fibers a (TRKb+) and fibers C (galanin+/neurotensin+) in nociceptive and pathological pain, BP.DR
19/14285-3 - Role of succinate/SUCNR1 signalling pathway in sensory neurons in neuropathic pain development, BP.DR
19/09901-7 - Biochemical and pharmacological characterization of oxytocin forms in New World Monkeys: activities on oxytocin and vasopressin receptors, BP.PD
19/19555-9 - Development of a transgenic line, with the conditioned expression of Cre recombinase protein to the activation Sucnr1/Gpr91 endogenous promoter., BP.PD
19/13829-0 - Role of O-GlcNAcylation in the neuroinflammatory functions of astrocytes, BP.DR
19/18645-4 - Understanding the immune response to Leishmania infantum, BP.PD
19/10473-0 - Chemical library screening and structural and biochemical characterization of ligands of novel molecular targets for the treatment of inflammatory diseases., BP.PD
19/04888-2 - Awareness and inflammation: the diffusion of topics related to inflammation and inflammatory diseases, BP.TT
19/08177-3 - The generation of astrocytes derived from human induced pluripotent stem cells (hiPSC): a powerful tool for the neuroinflammation study, BP.IC
18/24063-5 - Role of CCL-2/MCP-1 produced by peripheral sensorial neurons in the development of neuropathic pain, BP.DR
18/23910-6 - Role of PFKFB-3 enzyme in regulatory t cells, BP.MS
18/23168-8 - Importance of AMP-activated protein kinase (AMPK) in the regulation of TGF-beta pathway and T regulatory cells differentiation, BP.DR
18/22802-5 - Origin, dynamics and transcriptional profile of macrophages of the sensory ganglia of the dorsal roots and sciatic nerve, BP.MS
18/20130-0 - Function, mechanisms of activation and regulation of PI3K delta and PI3K gamma signaling pathway in the control of Trypanosoma cruzi infection., BP.PD
18/19312-6 - Role of S100A9/TLR4 pathway in the metabolic and functional modulation of keratinocytes and activation of dendritic cells: implications on the Psoriasis pathogenesis, BP.DR
17/26095-9 - Expression and activity of NRF2 in aorta of mice with insulin resistance submitted to the caloric restriction, BP.IC
18/05102-0 - Cellular metabolite profile analysis in neuropathic pain, BP.PD
17/25308-9 - Role of lactic acid in the resistance to checkpoint inhibitors (anti-PD-1/PD-L1) used in cancer immunotherapy, BP.PD
18/09509-7 - Proteomic approach for the evaluation of pathways related to the control of Leishmania major infection dependent on nitric oxide (NO), BP.IC
18/10444-7 - Evaluation of Naip receptors in NLRC4 inflammasome activation in response to L. amazonensis infection, BP.IC
17/21926-0 - Influence of the neutrophil infection upon the virulence factors of the Leishmania mexicana and Leishmania major parasites, BE.PQ
17/24669-8 - Unraveling the molecular bases of the early protein secretory pathway in humans using biophysical techniques, BP.PD
18/04782-7 - Awareness and inflammation: the dissemination of themes concerning inflammation and inflammatory diseases, BP.TT
17/12487-2 - Studying Juvenile Idiopathic Arthritis through a network Medicine approach, BP.DD
18/02587-2 - Histological processing in bone tissue, BP.TT
17/20692-5 - Regulation and function of O-GlcNAcylation in TAM macrophage differentiation and tumor progression, BP.DR
17/18264-5 - Biased agonists for the Gq protein pathway in the a1-adrenoceptor subtypes in Septic Vasoplegia treatment, BP.PD
17/19040-3 - Use of high-content screening to evaluate drug leishmanicidal activity in macrophages, BP.PD
17/04347-6 - Cooperation between TLR4 and IL-1R signaling pathways in the regulation of immune response during human and murine L. infantum infection, BP.PD
17/13353-0 - Association between inflammation and use of cannabis (Cannabis sativa) in patients in first psychotic episode, BP.IC
17/11270-0 - Awareness and inflammation: the dissemination of themes concerning inflammation and inflammatory diseases, BP.TT
17/01714-8 - PKM2 contribution to neutrophils' activation in experimental systemic lupus erythematosus onset, BP.PD
17/03203-0 - Planning of new candidates for anti-inflammatory drugs, BP.PD
17/06007-8 - Role of methotrexate and pro-resolving mediators in rheumatoid arthritis and in inflammatory response resolution process, BP.PD
17/03491-6 - RIDCs: Research, Innovation and Dissemination Centers, BP.PD
17/04936-1 - Evaluating the in vivo effect of potential drugs for the treatment of Arthritis, BP.PD
17/04200-5 - NEDD4L protein role in the differentiation regulation of TGF-²-induced Treg lymphocytes , BP.PD
17/03775-4 - Control of Sepsis-induced vital organs damage through glycolysis pathway modulation, BP.PD
17/03211-3 - The role of the H2S donor, ATB-346, in the evolution of experimental sepsis, BP.IC
16/24155-1 - Biased agonists for the Gq protein pathway in the a1-adrenoceptor subtypes in Septic Vasoplegia treatment, BP.PD
16/24049-7 - Role of interleukin-17 in the pathogenesis of Legionella longbeachae infection in vivo, BP.IC
16/24050-5 - Evaluation of caspase-8 activity regulation by caspase-1 in response to Legionella pneumophila infection, BP.IC
16/18357-0 - Phenotypic and transcriptome evaluation of murine and human leukocytes in Leishmania infantum infection, BP.PD
16/10280-9 - Involvement of the enzyme pyruvate kinase M2 (PKM2) in the differentiation of Th17 lymphocytes and pathogenesis of experimental autoimmune encephalomyelitis, BP.MS
16/11405-0 - Immuno-molecular mechanisms involved in the resistance to the development of immunosuppression in neonatal sepsis, BP.DR
16/17773-0 - Validation of new pharmacological hits for the treatment of inflammatory diseases and pain, BP.PD
16/16207-1 - Center for Research on Inflammatory Diseases - CRID, BP.PD
16/14188-0 - Relationship of endoplasmic reticulum stress, autophagy, inflammasome and nitric oxide production in inflammatory infectious processes, BP.PD
16/13154-4 - Synthesis and biological evaluation of lysine specific demethylase 1 (LSD-1), BP.IC
16/07602-4 - Role of Dectin-1 and Syk kinase evaluation in Nlrp3 inflammasome activation in murine macrophages infected with L. amazonensis, BP.IC
16/10867-0 - Development of HaCaT keratinocyte cell line knockouts for PKM2 enzyme, BP.IC
16/05377-3 - Role of Erk5 pathway on Th17 and Treg cells differentiation and on experimental autoimmune encephalomyelitis, BP.DR
16/07492-4 - New molecular targets cloning and expression for inflammatory diseases treatment and functional assays validation for selective binders identification, BP.PD
14/24162-2 - Analyses of the regulatory transcriptional mechanisms mediated by miRNAs in metabolic syndrome, BP.DD
15/25289-9 - Identification and validation of essential genes responsible for the immune response induction in patients with visceral leishmaniasis, BP.DR
15/25825-8 - Analysis of metabolic regulatory networks in inflammation, BP.PD
14/18566-3 - Center for Research in Inflammatory Diseases, BP.PD
15/03620-5 - Ubiquitination process and autophagic activity evaluation during macrophages infection with Leishmania spp., BP.IC
14/17740-0 - Planning, development and pharmacological evaluation of new aryl hydrocarbon receptors (AhR) antagonists that are candidates for atheroprotective drugs, BP.PD
14/11009-1 - Planning of new candidates for anti-inflammatory drugs design, BP.PD
14/16630-6 - Characterization of a luciferase expression assay induced by aryl hydrocarbon receptor activation, BP.IC
13/15994-1 - The role of NOD1 and NOD2 receptors in the control of Leishmania (L.) major infection, BP.PD
13/00579-9 - Role of inflammasomes and IL-1 in experimental infection by Trypanosoma cruzi, BP.PD
12/23846-0 - Role of succinate/GPR91 signaling in the physiopathology of neuropathic pain, BP.PD
12/08240-8 - Role of Blimp-1 in differentiation and function of Th9 cells., BP.PD
12/10100-0 - The role of ectonucleotidases and adenosine in the establishment of sepsis-induced immunosuppression, BP.PD
12/02438-0 - Role of the induced miRNAs after the aryl hydrocarbon receptor (AhR) activation and their functions in the pathogenesis of rheumatoid arthritis, BP.PD - associated scholarships

Abstract

Inflammatory diseases are a complex and heterogeneous group of diseases that affect more than 10% of the word population. The current options for the treatment of these diseases are still limited and in some cases, inefficient due to limited understanding of the mechanisms underlying these diseases. The development of translational research by a center that can generate scientific knowledge and also identify new therapeutic targets of inflammatory diseases is imperative. The Center for research in inflammatory diseases (CPDI) will be created with this goal. The general objective of the CPDI will be to perform integrative and translational research to identify, validate and target known and novel biological pathways involved with the induction and resolution of inflammation. As a result, we expect the development of innovative therapeutic strategies and drugs that effectively target inflammatory diseases. The project will involve high-throughput genetic screenings, in vivo and in vitro models of diseases, modeling and chemical synthesis, as well as the discovery of new natural molecules from plants and saliva from arthropods. After selecting the potential drugs and bio-drugs, CPDI will protect the intellectual property and, after partnerships with private companies, coordinate pre-clinical toxicological studies and early clinical trials. The CPDI will also dedicate intense efforts to disseminate knowledge to the general public, in order to fulfill the societal objective of spreading education and generating an enthusiasm for science. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
More itemsLess items
Articles published in other media outlets ( ):
More itemsLess items
VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (322)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PERES, RAPHAEL SANCHES; LIEW, FOO Y.; TALBOT, JHIMMY; CARREGARO, VANESSA; OLIVEIRA, RENE D.; ALMEIDA, SERGIO L.; FRANCA, RAFAEL F. O.; DONATE, PAULA B.; PINTO, LARISSA G.; FERREIRA, FLAVIA I. S.; et al. Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America, v. 112, n. 8, p. 2509-2514, . (13/08216-2, 11/19670-0)
ZAMBONI, DARIO S.; LIMA-JUNIOR, DJALMA S.. Inflammasomes in host response to protozoan parasites. IMMUNOLOGICAL REVIEWS, v. 265, n. 1, SI, p. 156-171, . (13/08216-2, 14/04684-4)
MORICONI, ALESSIO; CUNHA, THIAGO M.; SOUZA, GUILHERME R.; LOPES, ALEXANDRE H.; CUNHA, FERNANDO Q.; CARNEIRO, VICTOR L.; PINTO, LARISSA G.; BRANDOLINI, LAURA; ARAMINI, ANDREA; BIZZARRI, CINZIA; et al. Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief. Proceedings of the National Academy of Sciences of the United States of America, v. 111, n. 47, p. 16937-16942, . (13/08216-2, 11/19670-0)
SISTI, FLAVIA; WANG, SOUJUAN; BRANDT, STEPHANIE L.; GLOSSON-BYERS, NICOLE; MAYO, LINDSEY D.; SON, YOUNG MIN; STURGEON, SARAH; FILGUEIRAS, LUCIANO; JANCAR, SONIA; WONG, HECTOR; et al. Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis. Science Signaling, v. 11, n. 528, . (13/08216-2, 11/19670-0)
SACRAMENTO, LAIS AMORIM; CUNHA, FERNANDO Q.; DE ALMEIDA, ROQUE PACHECO; DA SILVA, JOAO SANTANA; CARREGARO, VANESSA. Protective Role of 5-Lipoxigenase during Leishmania infantum Infection Is Associated with Th17 Subset. BIOMED RESEARCH INTERNATIONAL, . (13/08216-2, 12/14524-9)
PERNOMIAN, LARISSA; GIMENES, LILIAN R.; GOMES, MAYARA S.; DO VALE, BRUNO N.; CARDOSO, CRISTINA R. B.; DE OLIVEIRA, ANA M.; MOREIRA, JOSIMAR D.. Endothelinergic Contractile Hyperreactivity in Rat Contralateral Carotid to Balloon Injury: Integrated Role for ETB Receptors and Superoxide Anion. BIOMED RESEARCH INTERNATIONAL, . (13/08216-2, 12/00640-7, 14/17740-0, 12/09019-3, 09/01005-0)
DA COSTA, RAFAEL MENEZES; FAIS, RAFAEL S.; DECHANDT, CARLOS R. P.; LOUZADA-JUNIOR, PAULO; ALBERICI, LUCIANE C.; LOBATO, NUBIA S.; TOSTES, RITA C.. Increased mitochondrial ROS generation mediates the loss of the anti-contractile effects of perivascular adipose tissue in high-fat diet obese mice. British Journal of Pharmacology, v. 174, n. 20, SI, p. 3527-3541, . (13/08216-2, 10/17259-9)
XAVIER-ELSAS, PEDRO; DE LUCA, BIANCA; QUETO, TULIO; VIEIRA, BRUNO MARQUES; MASID-DE-BRITO, DANIELA; DAHAB, ELIZABETH CHEN; ALVES FILHO, JOSE CARLOS; CUNHA, FERNANDO Q.; GASPAR-ELSAS, MARIA IGNEZ C.. Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation. Mediators of Inflammation, . (13/08216-2)
BASSI, GABRIEL SHIMIZU; ULLOA, LUIS; SANTOS, VICTOR RODRIGUES; DEL VECCHIO, FLAVIO; DELFINO-PEREIRA, POLIANNA; RODRIGUES, GERSON JHONATAN; CASTANIA, JACI AIRTON; CUNHA, FERNANDO DE QUEIROZ; SALGADO, HELIO CESAR; CUNHA, THIAGO MATTAR; et al. Cortical stimulation in conscious rats controls joint inflammation. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 84, n. A, p. 201-213, . (13/20549-7, 13/08216-2, 11/20343-4, 12/04237-2)
LOUREIRO, CAMILA MARCELINO; CORSI-ZUELLI, FABIANA; FACHIM, HELENE APARECIDA; SHUHAMA, ROSANA; DE SOUZA CHAGAS, NATALIA MOTA; MENEZES, PAULO ROSSI; DEL-BEN, CRISTINA MARTA; LOUZADA-JUNIOR, PAULO. Plasma prevalence of anti-N-methyl-d-aspartate receptor IgG antibodies in early stages of psychosis. Ciênc. saúde coletiva, v. 26, n. 3, p. 1085-1094, . (17/17480-6, 13/08216-2, 13/11167-3, 17/00624-5, 16/12195-9, 12/05178-0, 15/02948-7)
BRANDAO, W. N.; DE OLIVEIRA, M. G.; ANDREONI, R. T.; NAKAYA, H.; FARIAS, A. S.; PERON, J. P. S.. Neuroinflammation at single cell level: What is new?. Journal of Leukocyte Biology, . (13/08216-2, 18/21934-5, 17/50137-3, 17/26170-0, 12/19278-6, 17/22504-1, 17/21363-5, 18/14933-2, 19/06372-3)
DE OLIVEIRA, AMANDA A.; PRIVIERO, FERNANDA; TOSTES, RITA C.; WEBB, R. CLINTON; NUNES, KENIA P.. Dissecting the interaction between HSP70 and vascular contraction: role of Ca2+ handling mechanisms. SCIENTIFIC REPORTS, v. 11, n. 1, . (13/08216-2)
COSTA, FREDERICO R. C.; LEITE, JEFFERSON A.; RASSI, DIANE M.; DA SILVA, JOSIANE F.; ELIAS-OLIVEIRA, JEFFERSON; GUIMARAES, JHEFFERSON B.; FOSS-FREITAS, MARIA C.; CAMARA, NIELS O. S.; PONTILLO, ALESSANDRA; TOSTES, RITA C.; et al. LRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabete. CELL REPORTS, v. 35, n. 8, . (12/10395-0, 18/14815-0, 13/08216-2)
SANCHES, TIAGO L. M.; CUNHA, LARISSA D.; SILVA, GRACE K.; GUEDES, PAULO M. M.; SILVA, JOAO SANTANA; ZAMBONI, DARIO S.. The Use of a Heterogeneously Controlled Mouse Population Reveals a Significant Correlation of Acute Phase Parasitemia with Mortality in Chagas Disease. PLoS One, v. 9, n. 3, . (10/50959-4, 13/08216-2)
PASSOS, GERALDO ALEIXO; MENDES-DA-CRUZ, DANIELLE AREAS; OLIVEIRA, ERNNA HERIDA. The thymic orchestration involving Aire, miRNAs, and cell-cell interactions during the induction of central tolerance. FRONTIERS IN IMMUNOLOGY, v. 6, . (13/08216-2, 13/17481-1)
QUIRINO, GUSTAVO F. S.; NASCIMENTO, MANUELA S. L.; DAVOLI-FERREIRA, MARCELA; SACRAMENTO, LAIS A.; LIMA, MIKHAEL H. F.; ALMEIDA, ROQUE P.; CARREGARO, VANESSA; SILVA, JOAO SANTANA. Interleukin-27 (IL-27) Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response. Infection and Immunity, v. 84, n. 8, p. 2289-2298, . (13/08216-2, 12/14524-9)
SILVA, RANGEL L.; CASTANHEIRA, FERNANDA V.; FIGUEIREDO, JOZI G.; BASSI, GABRIEL S.; FERREIRA, SERGIO H.; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.; KANASHIRO, ALEXANDRE. Pharmacological Beta-Adrenergic Receptor Activation Attenuates Neutrophil Recruitment by a Mechanism Dependent on Nicotinic Receptor and the Spleen. Inflammation, v. 39, n. 4, p. 1405-1413, . (13/08216-2, 11/20343-4, 11/19670-0, 13/01466-3, 12/04237-2)
BASSI, G. S.; KANASHIRO, A.; RODRIGUES, G. J.; CUNHA, F. Q.; COIMBRA, N. C.; ULLOA, L.. Brain Stimulation Differentially Modulates Nociception and Inflammation in Aversive and Non-aversive Behavioral Conditions. Neuroscience, v. 383, p. 191-204, . (13/08216-2, 12/04237-2, 13/20549-7, 11/20343-4)
TALBOT, JHIMMY; PERES, RAPHAEL S.; PINTO, LARISSA G.; OLIVEIRA, RENE D. R.; LIMA, KALIL A.; DONATE, PAULA B.; SILVA, JAQUELINE R.; RYFFEL, BERNARD; CUNHA, THIAGO M.; ALVES-FILHO, JOSE C.; et al. Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells. ARTHRITIS RESEARCH & THERAPY, v. 20, . (13/08216-2, 11/19670-0)
RAMOS-JUNIOR, ERIVAN S.; LEITE, GISELE A.; CARMO-SILVA, CECILIA C.; TAIRA, THAISE M.; NEVES, KARLA B.; COLON, DAVID F.; DA SILVA, LEA A. B.; SALVADOR, SERGIO L.; TOSTES, RITA C.; CUNHA, FERNANDO Q.; et al. Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice. Journal of Bone and Mineral Research, v. 32, n. 5, p. 974-984, . (15/09034-0, 13/08216-2, 12/50842-5, 14/11958-3)
SILVA, JAQUELINE R.; LOPES, ALEXANDRE H.; TALBOT, JHIMMY; CECILIO, NERRY T.; ROSSATO, MATEUS F.; SILVA, RANGEL L.; SOUZA, GUILHERME R.; SILVA, CASSIA R.; LUCAS, GUILHERME; FONSECA, BENEDITO A.; et al. Neuroimmune-Glia Interactions in the Sensory Ganglia Account for the Development of Acute Herpetic Neuralgia. JOURNAL OF NEUROSCIENCE, v. 37, n. 27, p. 6408-6422, . (10/12309-8, 13/08216-2, 11/19670-0)
STAURENGO-FERRARI, LARISSA; TREVELIN, SILVIA C.; FATTORI, VICTOR; NASCIMENTO, DANIELE C.; DE LIMA, KALIL A.; PELAYO, JACINTA S.; FIGUEIREDO, FLORENCIO; CASAGRANDE, RUBIA; FUKADA, SANDRA Y.; TEIXEIRA, MAURO M.; et al. Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of Staphylococcus aureus-lnduced Septic Arthritis. FRONTIERS IN IMMUNOLOGY, v. 9, . (13/08216-2, 11/19670-0)
PERES, RAPHAEL S.; DONATE, PAULA B.; TALBOT, JHIMMY; CECILIO, NERRY T.; LOBO, PATRICIA R.; MACHADO, CAIO C.; LIMA, KALIL W. A.; OLIVEIRA, RENE D.; CARREGARO, VANESSA; NAKAYA, I, HELDER; et al. TGF-beta signalling defect is linked to low CD39 expression on regulatory T cells and methotrexate resistance in rheumatoid arthritis. Journal of Autoimmunity, v. 90, p. 49-58, . (13/08216-2, 12/10438-0, 09/54014-7)
HUANG, LEI; OU, RONG; DE SOUZA, GUILHERME RABELO; CUNHA, THIAGO M.; LEMOS, HENRIQUE; MOHAMED, ESLAM; LI, LINGQIAN; PACHOLCZYK, GABRIELA; RANDALL, JANICE; MUNN, DAVID H.; et al. Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase. PLOS PATHOGENS, v. 12, n. 5, . (13/08216-2, 11/19670-0)
BASSI, GABRIEL S.; MALVAR, DAVID DO C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; KANASHIRO, ALEXANDRE. Spinal GABA-B receptor modulates neutrophil recruitment to the knee joint in zymosan-induced arthritis. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, v. 389, n. 8, p. 851-861, . (13/08216-2, 12/04237-2, 11/19670-0, 11/20343-4)
FRANCHIN, MARCELO; ROSALEN, PEDRO LUIZ; DA CUNHA, MARCOS GUILHERME; SILVA, RANGEL LEAL; COLON, DAVID F.; BASSI, GABRIEL SHIMIZU; DE ALENCAR, SEVERINO MATIAS; IKEGAKI, MASAHARU; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; et al. Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-kappa B. Journal of Natural Products, v. 79, n. 7, p. 1828-1833, . (12/22378-2, 13/08216-2, 12/01365-0)
CUNHA, LARISSA D.; RIBEIRO, JULIANA M.; FERNANDES, TALITA D.; MASSIS, LILIANA M.; KHOO, CHEN AI; MOFFATT, JENNIFER H.; NEWTON, HAYLEY J.; ROY, CRAIG R.; ZAMBONI, DARIO S.. Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA. NATURE COMMUNICATIONS, v. 6, . (14/50268-2, 13/08216-2, 14/04684-4)
FRANCA, R. F. O.; VIEIRA, S. M.; TALBOT, J.; PERES, R. S.; PINTO, L. G.; ZAMBONI, D. S.; LOUZADA-JUNIOR, P.; CUNHA, F. Q.; CUNHA, T. M.. Expression and activity of NOD1 and NOD2/RIPK2 signalling in mononuclear cells from patients with rheumatoid arthritis. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, v. 45, n. 1, p. 8-12, . (10/19770-2, 13/08216-2, 11/19670-0)
CZAIKOSKI, PAULA GISELLE; SEGUNDO CORREIA MOTA, JOSE MAURCIO; NASCIMENTO, DANIELE CARVALHO; SONEGO, FABIANE; VARGAS E SILVA CASTANHEIRA, FERNANDA; MELO, PAULO HENRIQUE; SCORTEGAGNA, GABRIELA TRENTIN; SILVA, RANGEL LEAL; BARROSO-SOUSA, ROMUALDO; SOUTO, FABRICIO OLIVEIRA; et al. Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis. PLoS One, v. 11, n. 2, . (13/08216-2, 11/19670-0)
LOUREIRO, C. M.; SHUHAMA, R.; FACHIM, H. A.; MENEZES, P. R.; DEL-BEN, C. M.; LOUZADA-JUNIOR, P.. Low plasma concentrations of N-methyl-D-aspartate receptor subunits as a possible biomarker for psychosis. SCHIZOPHRENIA RESEARCH, v. 202, p. 55-63, . (12/05178-0, 13/08216-2)
BERTOLINI, THAIS B.; PINEROS, ANNIE R.; PRADO, RAFAEL Q.; GEMBRE, ANA FLAVIA; RAMALHO, LEANDRA N. Z.; ALVES-FILHO, JOSE CARLOS; BONATO, VANIA L. D.. CCR4-dependent reduction in the number and suppressor function of CD4(+)Foxp3(+) cells augments IFN-gamma-mediated pulmonary inflammation and aggravates tuberculosis pathogenesis. CELL DEATH & DISEASE, v. 10, . (13/08216-2, 11/09702-2)
DE CARVALHO, RENAN V. H.; ANDRADE, WARRISON A.; LIMA-JUNIOR, DJALMA S.; DILUCCA, MARISA; DE OLIVEIRA, V, CAROLINE; WANG, KUN; NOGUEIRA, PAULA M.; RUGANI, JERONIMO N.; SOARES, RODRIGO P.; BEVERLEY, STEPHEN M.; et al. Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome. CELL REPORTS, v. 26, n. 2, p. 429+, . (13/08216-2, 14/04684-4)
LOPES, ALEXANDRE H.; TALBOT, JHIMMY; SILVA, RANGEL L.; LIMA, JONILSON B.; FRANCA, RAFAEL O.; VERRI, JR., WALDICEU A.; MASCARENHAS, DANIELLE P.; RYFFEL, BERNHARD; CUNHA, FERNANDO Q.; ZAMBONI, DARIO S.; et al. Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain. Pain, v. 156, n. 3, p. 451-459, . (13/08216-2, 11/19670-0)
MASCARENHAS, DANIELLE P. A.; PEREIRA, MARCELO S. F.; MANIN, GRAZIELE Z.; HORI, JULIANA I.; ZAMBONI, DARIO S.. Interleukin 1 Receptor-Driven Neutrophil Recruitment Accounts to MyD88-Dependent Pulmonary Clearance of Legionella pneumophila Infection In Vivo. Journal of Infectious Diseases, v. 211, n. 2, p. 322-330, . (13/08216-2, 14/04684-4, 12/09363-6)
CORSI-ZUELLI, FABIANA; FACHIM, HELENE APARECIDA; LOUREIRO, CAMILA MARCELINO; SHUHAMA, ROSANA; BERTOZI, GIULIANO; JOCA, SAMIA REGIANE LOURENGO; MENEZES, PAULO ROSSI; LOUZADA-JUNIOR, PAULO; DEL-BEN, CRISTINA MARTA. Prolonged Periods of Social Isolation From Weaning Reduce the Anti-inflammatory Cytokine IL-10 in Blood and Brain. FRONTIERS IN NEUROSCIENCE, v. 12, . (13/11167-3, 13/08216-2, 17/00624-5, 16/12195-9, 15/02948-7, 17/17480-6, 12/05178-0)
LIMA, VICTOR V.; GIACHINI, FERNANDA R.; MATSUMOTO, TAKAYUKI; LI, WEIGUO; BRESSAN, ALECSANDER F. M.; CHAWLA, DHRUV; WEBB, R. CLINTON; ERGUL, ADVIYE; TOSTES, RITA C.. High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity?. Clinical Science, v. 130, n. 11, p. 871-880, . (13/08216-2)
PINHO-RIBEIRO, FELIPE A.; FATTORI, VICTOR; ZARPELON, ANA C.; BORGHI, SERGIO M.; STAURENGO-FERRARI, LARISSA; CARVALHO, THACYANA T.; ALVES, JOSE C.; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.; CASAGRANDE, RUBIA; et al. Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-kappa B and oxidative stress. INFLAMMOPHARMACOLOGY, v. 24, n. 2-3, p. 97-107, . (13/08216-2, 11/19670-0)
PINHO-RIBEIRO, FELIPE A.; ZARPELON, ANA C.; MIZOKAMI, SANDRA S.; BORGHI, SERGIO M.; BORDIGNON, JULIANO; SILVA, RANGEL L.; CUNHA, THIAGO M.; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; CASAGRANDE, RUBIA; et al. The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-kappa B activation. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, v. 33, p. 8-14, . (13/08216-2, 11/19670-0)
FRANCA, RAFAEL F. O.; COSTA, RENATA S.; SILVA, JAQUELINE R.; PERES, RAPHAEL S.; MENDONCA, LEILA R.; COLON, DAVID F.; ALVES-FILHO, JOSE CARLOS; CUNHA, FERNANDO Q.. IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system. JOURNAL OF NEUROINFLAMMATION, v. 13, . (10/19770-2, 13/08216-2, 11/19670-0)
YAMACITA-BORIN, FABIANE Y.; ZARPELON, ANA C.; PINHO-RIBEIRO, FELIPE A.; FATTORI, VICTOR; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.; CASAGRANDE, RUBIA; VERRI, JR., WALDICEU A.. Superoxide anion-induced pain and inflammation depends on TNF alpha/TNFR1 signaling in mice. Neuroscience Letters, v. 605, p. 53-58, . (13/08216-2, 11/19670-0)
FATTORI, VICTOR; PINHO-RIBEIRO, FELIPE A.; BORGHI, SERGIO M.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; CASAGRANDE, RUBIA; VERRI, JR., WALDICEU A.. Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-kappa B activation. Inflammation Research, v. 64, n. 12, p. 993-1003, . (13/08216-2, 11/19670-0)
PERNOMIAN, LARISSA; PERNOMIAN, LAENA; GOMES, MAYARA S.; DA SILVA, CARLOS H. T. P.. Pharmacological significance of the interplay between angiotensin receptors: MAS receptors as putative final mediators of the effects elicited by angiotensin ATi receptors antagonists. European Journal of Pharmacology, v. 769, p. 143-146, . (14/17740-0, 13/08216-2, 12/00640-7, 11/11205-7)
TREVELIN, SILVIA CELLONE; DOS SANTOS, CELIO XAVIER; FERREIRA, RAPHAEL GOMES; LIMA, LARISSA DE SA; SILVA, RANGEL LEAL; SCAVONE, CRISTOFORO; CURI, RUI; CARLOS ALVES-FILHO, JOSE; CUNHA, THIAGO MATTAR; ROXO-JUNIOR, PERSIO; et al. Apocynin and Nox2 regulate NF-kappa B by modifying thioredoxin-1 redox-state. SCIENTIFIC REPORTS, v. 6, . (12/24677-7, 09/54764-6, 13/08216-2, 13/03520-5, 11/19670-0, 11/03293-3, 13/07937-8)
FERNANDES, TALITA D.; CUNHA, LARISSA D.; RIBEIRO, JULIANA M.; MASSIS, LILIANA M.; LIMA-JUNIOR, DJALMA S.; NEWTON, HAYLEY J.; ZAMBONI, DARIO S.. Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro. Infection and Immunity, v. 84, n. 9, p. 2439-2448, . (14/50268-2, 13/08216-2, 14/04684-4)
MACEDO, CLAUDIA; OLIVEIRA, ERNNA H.; ALMEIDA, RENATA S.; DONATE, PAULA B.; FORNARI, THAIS A.; PEZZI, NICOLE; SAKAMOTO-HOJO, ELZA T.; DONADI, EDUARDO A.; PASSOS, GERALDO A.. Aire-dependent peripheral tissue antigen mRNAs in mTEC cells feature networking refractoriness to microRNA interaction. Immunobiology, v. 220, n. 1, p. 93-102, . (13/08216-2, 13/17481-1, 08/56594-8)
DE SOUSA BARROS, JESSICA BARLETTO; NEVES DA SILVA, PAULO ALEX; ROCHA KOGA, ROSEMARY DE CARVALHO; GONZALEZ-DIAS, PATRICIA; CARMO FILHO, JOSE RODRIGUES; ALO NAGIB, PATRICIA RESENDE; COELHO, VERONICA; NAKAYA, HELDER I.; FONSECA, SIMONE GONCALVES; HOFFMANN PFRIMER, IRMTRAUT ARACI. Acute Zika Virus Infection in an Endemic Area Shows Modest Proinflammatory Systemic Immunoactivation and Cytokine-Symptom Associations. FRONTIERS IN IMMUNOLOGY, v. 9, . (13/08216-2)
CERQUEIRA, DAIANE M.; PEREIRA, MARCELO S. F.; SILVA, ALEXANDRE L. N.; CUNHA, LARISSA D.; ZAMBONI, DARIO S.. Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by Flagellated Legionella Species in Mouse Macrophages and In Vivo. JOURNAL OF IMMUNOLOGY, v. 195, n. 5, p. 2303-2311, . (12/14456-3, 11/22617-4, 13/08216-2, 14/04684-4, 12/15932-3, 12/16941-6)
BONFA, GIULIANO; BENEVIDES, LUCIANA; SOUZA, MARIA DO CARMO; FONSECA, DENISE MORAIS; PATRIARCA MINEO, TIAGO WILSON; ROSSI, MARCOS ANTONIO; SILVA, NEIDE MARIA; SILVA, JOAO SANTANA; DE BARROS CARDOSO, CRISTINA RIBEIRO. CCR5 Controls Immune and Metabolic Functions during Toxoplasma gondii Infection. PLoS One, v. 9, n. 8, . (13/08216-2, 12/14524-9)
SONEGO, FABIANE; ALVES-FILHO, JOSE CARLOS; CUNHA, FERNANDO QUEIROZ. Targeting neutrophils in sepsis. EXPERT REVIEW OF CLINICAL IMMUNOLOGY, v. 10, n. 8, p. 1019-1028, . (13/08216-2, 11/19670-0)
PERNOMIAN, LARISSA; GOMES, MAYARA S.; PERNOMIAN, LAENA; MOREIRA, RAFAEL P.; CORREA, FERNANDO M. A.; DE OLIVEIRA, ANA M.. Vasoprotective effects of neurocompensatory response to balloon injury during diabetes involve the improvement of Mas signaling by TGF beta(1) activation. VASCULAR PHARMACOLOGY, v. 64, p. 36-48, . (14/17740-0, 09/01005-0, 11/11205-7, 12/00640-7, 13/08216-2)
FREITAS, CRISTINA S.; ROVEDA, ANTONIO C.; TRUZZI, JR., DANIELA R.; GARCIA, ANDRE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; FRANCO, DOUGLAS W.. Anti-inflammatory and Anti-nociceptive Activity of Ruthenium Complexes with Isonicotinic and Nicotinic Acids (Niacin) as Ligands. Journal of Medicinal Chemistry, v. 58, n. 11, p. 4439-4448, . (12/23651-4, 13/08216-2, 11/19670-0)
LIMA, MIKHAEL H. F.; SACRAMENTO, LAIS A.; QUIRINO, GUSTAVO F. S.; FERREIRA, MARCELA D.; BENEVIDES, LUCIANA; SANTANA, ALYNNE K. M.; CUNHA, FERNANDO Q.; ALMEIDA, ROQUE P.; SILVA, JOAO S.; CARREGARO, VANESSA. Leishmania infantum Parasites subvert the host inflammatory response through the adenosine A2(A) receptor to Promote the establishment of infection. FRONTIERS IN IMMUNOLOGY, v. 8, . (15/12526-2, 13/08216-2)
PINEROS ALVAREZ, ANNIE ROCIO; GLOSSON-BYERS, NICOLE; BRANDT, STEPHANIE; WANG, SOUJUAN; WONG, HECTOR; STURGEON, SARAH; MCCARTHY, BRIAN PAUL; TERRITO, PAUL R.; ALVES-FILHO, JOSE CARLOS; HENRIQUE SEREZANI, C.. SOCS1 is a negative regulator of metabolic reprogramming during sepsis. JCI INSIGHT, v. 2, n. 13, . (13/08216-2, 11/19670-0)
P. MEDEIROS; I.R. DOS SANTOS; A.C. MEDEIROS; J.A. DA SILVA; S.H. FERREIRA; R.L. DE FREITAS; N.C. COIMBRA. Indomethacin attenuates mechanical allodynia during the organization but not the maintenance of the peripheral neuropathic pain induced by nervus ischiadicus chronic constriction injury. Brazilian Journal of Medical and Biological Research, v. 53, n. 5, . (14/07902-2, 12/25167-2, 17/13560-5, 14/11869-0, 13/08216-2, 13/12916-0, 11/19670-0, 09/17258-5)
KANASHIRO, ALEXANDRE; HIROKI, CARLOS HIROJI; DA FONSECA, DENISE MORAIS; BIRBRAIR, ALEXANDER; FERREIRA, RAPHAEL GOMES; BASSI, GABRIEL SHIMIZU; FONSECA, MIRIAN D.; KUSUDA, RICARDO; MARTELOSSI CEBINELLI, GUILHERME CESAR; DA SILVA, KATIUSSIA PINHO; et al. The role of neutrophils in neuro-immune modulation. PHARMACOLOGICAL RESEARCH, v. 151, . (16/08385-7, 13/08216-2, 11/20343-4, 11/19670-0, 12/04237-2)
SCHNEIDER, AYDA HENRIQUES; MACHADO, CAIO CAVALCANTE; VERAS, FLAVIO PROTASIO; DE MACEDO MAGANIN, ALEXANDRE GOMES; LIMA DE SOUZA, FLAVIO FALCAO; BARROSO, LIVIA CORREA; RIBEIRO DE OLIVEIRA, RENE DONIZETI; ALVES-FILHO, JOSE CARLOS; CUNHA, THIAGO MATTAR; FUKADA, SANDRA YASUYO; et al. Neutrophil extracellular traps mediate joint hyperalgesia induced by immune inflammation. RHEUMATOLOGY, v. 60, n. 7, p. 3461-3473, . (13/08216-2)
SILVA, CARLA B. P.; ELIAS-OLIVEIRA, JEFFERSON; MCCARTHY, CAMERON G.; WENCESLAU, CAMILLA F.; CARLOS, DANIELA; TOSTES, RITA C.. Ethanol: striking the cardiovascular system by harming the gut microbiota. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 321, n. 2, p. H275-H291, . (18/14815-0, 13/08216-2)
DE OLIVEIRA, AMANDA A.; PRIVIERO, FERNANDA; TOSTES, RITA C.; WEBB, R. CLINTON; NUNES, KENIA P.. Dissecting the interaction between HSP70 and vascular contraction: role of Ca2+ handling mechanisms. SCIENTIFIC REPORTS, v. 11, n. 1, p. 11-pg., . (13/08216-2)
BENEVIDES, LUCIANA; SALTARELLI, VERONICA M.; PIOTO, FRANCIELE; SACRAMENTO, LAIS A.; DIAS, MURILO S.; RODRIGUEZ, GRETEL R.; VIOLA, JOAO P. B.; CARREGARO, VANESSA; SILVA, JOAO S.. NFAT1 Regulates Ly6C(hi) Monocyte Recruitment to the CNS and Plays an Essential Role in Resistance to Toxoplasma gondii Infection. FRONTIERS IN IMMUNOLOGY, v. 10, . (13/08216-2)
MEDEIROS, PRISCILA; NEGRINI-FERRARI, SYLMARA ESTHER; PALAZZO, ENZA; MAIONE, SABATINO; FERREIRA, SERGIO HENRIQUE; DE FREITAS, RENATO LEONARDO; COIMBRA, NORBERTO CYSNE. N-methyl-d-aspartate Receptors in the Prelimbic Cortex are Critical for the Maintenance of Neuropathic Pain. Neurochemical Research, v. 44, n. 9, p. 2068-2080, . (14/11869-0, 12/25167-2, 13/08216-2, 13/12916-0, 11/19670-0, 17/13560-5, 09/17258-5, 14/07902-2)
BORGHI, SERGIO M.; BUSSULO, SYLVIA K. D.; PINHO-RIBEIRO, FELIPE A.; FATTORI, VICTOR; CARVALHO, THACYANA T.; RASQUEL-OLIVEIRA, FERNANDA S.; ZANINELLI, TIAGO H.; FERRAZ, CAMILA R.; CASELLA, ANTONIO M. B.; CUNHA, FERNANDO Q.; et al. ntense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammatio. FRONTIERS IN PHARMACOLOGY, v. 12, . (13/08216-2)
OLIVEIRA, SICILIA REZENDE; ALMEIDA DE ARRUDA, JOSE ALCIDES; SCHNEIDER, AYDA HENRIQUES; CARVALHO, VALESSA FLORINDO; MACHADO, CAIO CAVALCANTE; CORREA, JOICE DIAS; MOURA, MARCELA FARIA; DUFFLES, LETICIA FERNANDA; LIMA DE SOUZA, FLAVIO FALCAO; FERREIRA, GILDA APARECIDA; et al. re neutrophil extracellular traps the link for the cross-talk between periodontitis and rheumatoid arthritis physiopathology. RHEUMATOLOGY, v. 61, n. 1, p. 174-184, . (13/08216-2)
SILVA, CAMILA MEIRELLES S.; WANDERLEY, CARLOS WAGNER S.; VERAS, FLAVIO P.; SONEGO, FABIANE; NASCIMENTO, DANIELE C.; GONCALVES, AUGUSTO V.; MARTINS, TIMNA V.; COLON, DAVID F.; BORGES, VANESSA F.; BRAUER, VERONICA S.; et al. asdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formatio. Blood, v. 138, n. 25, p. 2702-2713, . (13/08216-2)
OLIVEIRA, SICILIA REZENDE; DE ARRUDA, JOSE ALCIDES ALMEIDA; SCHNEIDER, AYDA HENRIQUES; CARVALHO, VALESSA FLORINDO; MACHADO, CAIO CAVALCANTE; CORREA, JOICE DIAS; MOURA, MARCELA FARIA; DUFFLES, LETICIA FERNANDA; DE SOUZA, FLAVIO FALCAO LIMA; FERREIRA, GILDA APARECIDA; et al. re neutrophil extracellular traps the link for the cross-talk between periodontitis and rheumatoid arthritis physiopathology. RHEUMATOLOGY, v. 61, n. 1, p. 174-184, . (13/08216-2)
CORSI-ZUELLI, FABIANA; LOUREIRO, CAMILA MARCELINO; SHUHAMA, ROSANA; FACHIM, HELENE APARECIDA; MENEZES, PAULO ROSSI; LOUZADA-JUNIOR, PAULO; MONDELLI, VALERIA; DEL-BEN, CRISTINA MARTA. Cytokine profile in first-episode psychosis, unaffected siblings and community-based controls: the effects of familial liability and childhood maltreatment. PSYCHOLOGICAL MEDICINE, v. 50, n. 7, p. 1139-1147, . (12/05178-0, 16/12195-9, 13/11167-3, 13/08216-2, 17/17480-6, 15/02948-7)
SILVA, MARIA CLAUDIA; BONFIM CARBONE, DEBORA CARDOZO; DINIZ, PEDRO FERNANDO; FERNANDES, FABRICIO FREITAS; FUZO, CARLOS ALESSANDRO; PEREIRA CARDOSO TRINDADE, CAROLINA SANTOS; CHANG, MARILENE RODRIGUES; SILVA, JOAO SANTANA. Modulation of ERG Genes Expression in Clinical Isolates of Candida tropicalis Susceptible and Resistant to Fluconazole and Itraconazole. Mycopathologia, v. 185, n. 4, . (13/08216-2)
COSTA, TIAGO J.; POTJE, SIMONE R.; FRAGA-SILVA, THAIS F. C.; DA SILVA-NETO, JULIO A.; BARROS, PAULA R.; RODRIGUES, DANIEL; MACHADO, MIRELE R.; MARTINS, RONALDO B.; SANTOS-EICHLER, ROSANGELA A.; BENATTI, MAIRA N.; et al. itochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damag. VASCULAR PHARMACOLOGY, v. 142, . (13/08216-2, 16/21239-0, 17/25116-2)
SILVA, JAQUELINE RAYMONDI; IFTINCA, MIRCEA; GOMES, FRANCISCO I. FERNANDES; SEGAL, JULIA P.; SMITH, OLIVIA M. A.; BANNERMAN, COURTNEY A.; MENDES, ATLANTE SILVA; DEFAYE, MANON; ROBINSON, MADELINE E. C.; GILRON, IAN; et al. kin-resident dendritic cells mediate postoperative pain via CCR4 on sensory neuron. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 119, n. 4, . (13/08216-2)
ANDRADE, WARRISON A.; ZAMBONI, DARIO S.. NLRC4 biology in immunity and inflammation. Journal of Leukocyte Biology, v. 108, n. 4, p. 11-pg., . (19/11342-6, 14/04684-4, 13/08216-2, 18/14398-0)
AQUIME GONCALVES, ANDRE NICOLAU; MASO, VANESSA ESCOLANO; SANTOS DE CASTRO, ICARO MAIA; VASCONCELOS, AMANDA PEREIRA; TOMIO OGAVA, RODRIGO LUIZ; NAKAYA, HELDER, I. High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, v. N/A, n. 181, p. 22-pg., . (18/14933-2, 13/08216-2, 19/13880-5, 19/16418-0, 19/27146-1, 12/19278-6, 20/05284-0, 17/50137-3, 18/21934-5)
PINTO, BRUNA G. G.; OLIVEIRA, ANTONIO E. R.; SINGH, YOUVIKA; JIMENEZ, LEANDRO; GONCALVES, ANDRE N. A.; OGAVA, RODRIGO L. T.; CREIGHTON, RACHEL; SCHATZMANN PERON, JEAN PIERRE; NAKAYA, I, HELDER. ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19. Journal of Infectious Diseases, v. 222, n. 4, p. 556-563, . (12/19278-6, 18/14933-2, 18/21934-5, 13/08216-2, 17/50137-3)
FERREIRA, NATHANNE S.; TOSTES, RITA C.; PARADIS, PIERRE; SCHIFFRIN, ERNESTO L.. Aldosterone, Inflammation, Immune System, and Hypertension. AMERICAN JOURNAL OF HYPERTENSION, v. 34, n. 1, p. 15-27, . (13/08216-2)
MEDEIROS, PRISCILA; DOS SANTOS, IEDA REGINA; MATIAS JUNIOR, IVAIR; PALAZZO, ENZA; DA SILVA, JOSE APARECIDO; MACHADO, HELIO RUBENS; FERREIRA, SERGIO HENRIQUE; MAIONE, SABATINO; COIMBRA, NORBERTO CYSNE; DE FREITAS, RENATO LEONARDO. An Adapted Chronic Constriction Injury of the Sciatic Nerve Produces Sensory, Affective, and Cognitive Impairments: A Peripheral Mononeuropathy Model for the Study of Comorbid Neuropsychiatric Disorders Associated with Neuropathic Pain in Rats. PAIN MEDICINE, v. 22, n. 2, p. 338-351, . (11/19670-0, 13/08216-2, 13/12916-0, 17/13560-5, 14/11869-0, 12/25167-2, 14/07902-2, 09/17258-5)
DOS PASSOS JUNIOR, RINALDO RODRIGUES; BOMFIM, GISELE FACHOLI; GIACHINI, FERNANDA R.; TOSTES, RITA C.; LIMA, VICTOR VITORINO. O-Linked beta-N-Acetylglucosamine Modification: Linking Hypertension and the Immune System. FRONTIERS IN IMMUNOLOGY, v. 13, p. 13-pg., . (13/08216-2)
FATTORI, VICTOR; STAURENGO-FERRARI, LARISSA; ZANINELLI, TIAGO H.; CASAGRANDE, RUBIA; OLIVEIRA, RENE D.; LOUZADA-JUNIOR, PAULO; CUNHA, THIAGO M.; ALVES-FILHO, JOSE C.; TEIXEIRA, MAURO M.; CUNHA, FERNANDO Q.; et al. IL-33 enhances macrophage release of IL-1 beta and promotes pain and inflammation in gouty arthritis. Inflammation Research, v. 69, n. 12, . (13/08216-2)
COSTA, RAFAEL M.; ALVES-LOPES, RHEURE; ALVES, JULIANO V.; SERVIAN, CAROLINA P.; MESTRINER, FABIOLA L.; CARNEIRO, FERNANDO S.; LOBATO, NUBIA DE S.; TOSTES, RITA C.. Testosterone Contributes to Vascular Dysfunction in Young Mice Fed a High Fat Diet by Promoting Nuclear Factor E2-Related Factor 2 Downregulation and Oxidative Stress. FRONTIERS IN PHYSIOLOGY, v. 13, p. 14-pg., . (13/08216-2)
MAGANIN, ALEXANDRE G.; SOUZA, GUILHERME R.; FONSECA, MIRIAM D.; LOPES, ALEXANDRE H.; GUIMARAES, RAFAELA M.; DAGOSTIN, ANDRE; CECILIO, NERRY T.; MENDES, ATLANTE S.; GONCALVES, WILLIAM A.; SILVA, CONCEICAO E. A.; et al. Meningeal dendritic cells drive neuropathic pain through elevation of the kynurenine metabolic pathway in mice. Journal of Clinical Investigation, v. 132, n. 23, p. 17-pg., . (13/08216-2, 11/19670-0)
COLON, DAVID F.; WANDERLEY, CARLOS W.; FRANCHIN, MARCELO; SILVA, CAMILA M.; HIROKI, CARLOS H.; CASTANHEIRA, FERNANDA V. S.; DONATE, PAULA B.; LOPES, ALEXANDRE H.; VOLPON, LEILA C.; KAVAGUTI, SILVIA K.; et al. Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis. Critical Care, v. 23, p. 13-pg., . (13/08216-2, 11/19670-0)
FONSECA, MIRIAM M.; DAVOLI-FERREIRA, MARCELA; SANTA-CECILIA, FLAVIA; GUIMARAES, RAFAELA M.; OLIVEIRA, FRANCISCO F. B.; KUSUDA, RICARDO; FERREIRA, DAVID W.; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.. IL-27 Counteracts Neuropathic Pain Development Through Induction of IL-10. FRONTIERS IN IMMUNOLOGY, v. 10, p. 14-pg., . (13/08216-2, 11/19670-0)
CARREGARO, VANESSA; NAPIMOGA, MARCELO H.; PERES, RAPHAEL S.; BENEVIDES, LUCIANA; SACRAMENTO, LAIS AMORIM; PINTO, LARISSA G.; GRESPAN, RENATA; CUNHA, THIAGO M.; DA SILVA, JOAO SANTANA; CUNHA, FERNANDO Q.. Therapeutic Treatment of Arthritic Mice with 15-Deoxy Delta(12,14)-Prostaglandin J(2) (15d-PGJ(2)) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4(+)CD25(-)FOXP3(+) Cells. Mediators of Inflammation, v. 2016, p. 13-pg., . (13/08216-2)
TOLLER-KAWAHISA, JULIANA ESCHER; HIROKI, CARLOS HIROJI; SILVA, CAMILA MEIRELLES DE SOUZA; NASCIMENTO, DANIELE CARVALHO; PUBLIO, GABRIEL AZEVEDO; MARTINS, TIMNA VARELA; DAMASCENO, LUIS EDUARDO ALVES; VERAS, FLAVIO PROTASIO; VIACAVA, PAULA RAMOS; SUKESADA, FABIO YUJI; et al. The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils. NATURE COMMUNICATIONS, v. 14, n. 1, p. 16-pg., . (13/08216-2, 19/25298-9, 17/01714-8, 20/02207-5)
VERAS, FLAVIO P.; GOMES, GIOVANNI F.; SILVA, BRUNA M. S.; CAETITE, DIEGO B.; ALMEIDA, CICERO J. L. R.; SILVA, CAMILA MEIRELLES S.; SCHNEIDER, AYDA H.; CORNEO, EMILY S.; BONILHA, CAIO S.; BATAH, SABRINA S.; et al. Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model. RESPIRATORY RESEARCH, v. 24, n. 1, p. 11-pg., . (13/08216-2, 20/05601-6)
SANTOS, JEIMISON D.; TOSTES, RITA C.; OLIVEIRA-NETO, JOSE T.. The cardiovascular subtleties of testosterone on gender-affirming hormone therapy. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 325, n. 1, p. 24-pg., . (13/08216-2)
CERNI, FELIPE; OLIVEIRA, ISADORA; CORDEIRO, FRANCIELLE; BORDON, KARLA; FERREIRA, ISABELA; MONTEIRO, WUELTON; ARANTES, ELIANE; CUNHA, THIAGO; PUCCA, MANUELA. The nociceptive response induced by different classes of Tityus serrulatus neurotoxins: The important role of Ts5 in venom-induced nociception. PLoS Neglected Tropical Diseases, v. 17, n. 1, p. 14-pg., . (20/13176-3, 19/10173-6, 13/08216-2)
GOMES, FRANCISCO ISAAC F.; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.. Peripheral nitric oxide signaling directly blocks inflammatory pain. Biochemical Pharmacology, v. 176, p. 11-pg., . (13/08216-2, 19/14285-3)
AGUIAR, RENATO S.; POHL, FABIO; MORAIS, GUILHERME L.; NOGUEIRA, FABIO C. S.; DE CARVALHO, JOSEANE B.; GUIDA, LETICIA; ARGE, LUIS W. P.; MELO, ADRIANA; MOREIRA, MARIA E. L.; CUNHA, DANIELA P.; et al. Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome. SCIENCE SIGNALING, v. 13, n. 635, p. 13-pg., . (13/08216-2, 17/50137-3, 18/14933-2, 18/21934-5, 12/19278-6)
LUIZ, JOAO PAULO M.; TOLLER-KAWAHISA, JULIANA E.; VIACAVA, PAULA R.; NASCIMENTO, DANIELE C.; PEREIRA, PRISCILLA T.; SARAIVA, ANDRE L.; PRADO, DOUGLAS S.; LE BERT, MARC; GIURISATO, EMANUELE; TOURNIER, CATHY; et al. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology, v. 108, n. 4, p. 9-pg., . (16/05377-3, 17/20692-5, 17/01714-8, 13/08216-2, 11/12671-1)
CORSI-ZUELLI, FABIANA; MARQUES, LEONARDO; DA ROZA, DAIANE LEITE; LOUREIRO, CAMILA MARCELINO; SHUHAMA, ROSANA; MENEZES, PAULO ROSSI; LOUZADA-JUNIOR, PAULO; DEL-BEN, CRISTINA MARTA. Cannabis Consumption Increases Risk of Psychosis in a Subgroup of Patients With High Peripheral Blood Inflammation. BIOLOGICAL PSYCHIATRY, v. 87, n. 9, p. 1-pg., . (13/08216-2, 19/13229-2, 12/05178-0)
LOPES, ALEXANDRE H.; SILVA, RANGEL L.; FONSECA, MIRIAM D.; GOMES, FRANCISCO I.; MAGANIN, ALEXANDRE G.; RIBEIRO, LUCAS S.; MARQUES, LUCAS MACIEL MAURIZ; CUNHA, FERNANDO Q.; ALVES-FILHO, JOSE C.; ZAMBONI, DARIO S.; et al. Molecular basis of carrageenan-induced cytokines production in macrophages. CELL COMMUNICATION AND SIGNALING, v. 18, n. 1, p. 17-pg., . (13/08216-2, 11/19670-0)
DA COSTA, RAFAEL MENEZES; FAIS, RAFAEL S.; DECHANDT, CARLOS R. P.; LOUZADA-JUNIOR, PAULO; ALBERICI, LUCIANE C.; LOBATO, NUBIA S.; TOSTES, RITA C.. Increased mitochondrial ROS generation mediates the loss of the anti-contractile effects of perivascular adipose tissue in high-fat diet obese mice. British Journal of Pharmacology, v. 174, n. 20, p. 15-pg., . (13/08216-2, 10/17259-9)
BECARI, CHRISTIANE; SILVA, MARCONDES A. B.; DURAND, MARINA T.; PRADO, CIBELE M.; OLIVEIRA, EDUARDO B.; RIBEIRO, MAURICIO S.; SALGADO, HELIO C.; SALGADO, MARIA CRISTINA O.; TOSTES, RITA C.. Elastase-2, an angiotensin II-generating enzyme, contributes to increased angiotensin II in resistance arteries of mice with myocardial infarction. British Journal of Pharmacology, v. 174, n. 10, p. 12-pg., . (13/08216-2)
NEVES, KARLA BIANCA; MONTEZANO, AUGUSTO CESAR; ALVES-LOPES, RHEURE; BRUDER-NASCIMENTO, THIAGO; COSTA, RAFAEL MENEZES; COSTA, ROBERTO S.; TOUYZ, RHIAN M.; TOSTES, RITA C.. Upregulation of Nrf2 and Decreased Redox Signaling Contribute to Renoprotective Effects of Chemerin Receptor Blockade in Diabetic Mice. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 19, n. 8, p. 15-pg., . (15/01630-3, 13/08216-2, 12/13144-8)
SANTOS, CAMILLA NATALIA O.; CALDAS, GUSTAVO C. C.; DE OLIVEIRA, FABRICIA A. A.; DA SILVA, ANGELA MARIA; DA SILVA, JOAO S.; DA SILVA, RICARDO LUIS L.; DE JESUS, AMELIA R.; MAGALHAES, LUCAS S. S.; DE ALMEIDA, ROQUE P. P.. COVID-19 recurrence is related to disease-early profile T cells while detection of anti-S1 IgG is related to multifunctional T cells. MEDICAL MICROBIOLOGY AND IMMUNOLOGY, v. 212, n. 5, p. 9-pg., . (13/08216-2)
MARTUCCI, LUIZ FELIPE; EICHLER, ROSANGELA A. S.; SILVA, RENEE N. O.; COSTA, TIAGO J.; TOSTES, RITA C.; BUSATTO, GERALDO F.; SEELAENDER, MARILIA C. L.; DUARTE, ALBERTO J. S.; SOUZA, HERALDO P.; FERRO, EMER S.. Intracellular peptides in SARS-CoV-2-infected patients. ISCIENCE, v. 26, n. 9, p. 17-pg., . (13/08216-2, 16/04000-3, 17/25116-2)
CORSI-ZUELLI, FABIANA; CARVALHO RAGAZZI, TACIANA CRISTINA; LOUREIRO, CAMILA MARCELINO; MENEZES, PAULO ROSSI; LOUZADA-JUNIOR, PAULO; DEL-BEN, CRISTINA MARTA. Signals of Adaptive Immune Activation in Non-Clinical Populations With Psychotic Experiences. BIOLOGICAL PSYCHIATRY, v. 89, n. 9, p. 1-pg., . (13/08216-2, 19/13229-2, 12/05178-0)
COSTA, FREDERICO R. C.; LEITE, JEFFERSON A.; RASSI, DIANE M.; DA SILVA, JOSIANE F.; ELIAS-OLIVEIRA, JEFFERSON; GUIMARAES, JHEFFERSON B.; FOSS-FREITAS, MARIA C.; CAMARA, NIELS O. S.; PONTILLO, ALESSANDRA; TOSTES, RITA C.; et al. NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes. CELL REPORTS, v. 35, n. 8, p. 15-pg., . (13/08216-2, 12/10395-0, 18/14815-0)
PERON, J. P. S.; NAKAYA, H., I; SCHLINDWEIN, M. A. M.; GONCALVES, M. V. M.. COVID-19 Pandemic and Dysbiosis: Can the Ivermectin Hysteria Lead to an Increase of Autoimmune Neuroinflammatory Diseases?. CRITICAL REVIEWS IN IMMUNOLOGY, v. 40, n. 6, p. 6-pg., . (17/22504-1, 19/06372-3, 13/08216-2, 17/21363-5, 18/14933-2, 18/21934-5, 12/19278-6)
LOUREIRO, CAMILA MARCELINO; CORSI-ZUELLI, FABIANA; FACHIM, HELENE APARECIDA; SHUHAMA, ROSANA; DE SOUZA CHAGAS, NATALIA MOTA; MENEZES, PAULO ROSSI; DEL-BEN, CRISTINA MARTA; LOUZADA-JUNIOR, PAULO. Plasma prevalence of anti-N-methyl-d-aspartate receptor IgG antibodies in early stages of psychosis. Ciênc. saúde coletiva, v. 26, n. 3, p. 10-pg., . (15/02948-7, 17/17480-6, 12/05178-0, 13/11167-3, 13/08216-2, 16/12195-9, 17/00624-5)
ALVES-FILHO, JOSE C.; PALSSON-MCDERMOTT, EVA M.. Pyruvate Kinase M2: A Potential Target for Regulating inflammation. FRONTIERS IN IMMUNOLOGY, v. 7, . (13/08216-2, 11/19670-0)
CECILIO, NERRY T.; SOUZA, GUILHERME R.; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.. The PI3K gamma/AKT signaling pathway mediates peripheral antinociceptive action of dipyrone. FUNDAMENTAL & CLINICAL PHARMACOLOGY, v. 35, n. 2, p. 364-370, . (13/08216-2, 11/19670-0)
PRADO, MORGANA K. B.; FONTANARI, CAROLINE; SOUZA, CAMILA O. S.; GARDINASSI, LUIZ G.; ZOCCAL, KARINA F.; DE PAULA-SILVA, FRANCISCO W. G.; PETI, ANA P. F.; SORGI, CARLOS A.; MEIRELLES, ALYNE F. G.; RAMOS, SIMONE G.; et al. IL-22 Promotes IFN-gamma-Mediated Immunity against Histoplasma capsulatum Infection. BIOMOLECULES, v. 10, n. 6, . (13/08216-2, 14/07125-6, 15/00658-1)
CARLOS, DANIELA; PEREZ, MALENA M.; LEITE, JEFFERSON A.; ROCHA, FERNANDA A.; MARTINS, LARISSA M. S.; PEREIRA, CAMILA A.; FRAGA-SILVA, THAIS F. C.; PUCCI, TAIS A.; RAMOS, SIMONE G.; CAMARA, NIELS O. S.; et al. NOD2 Deficiency Promotes Intestinal CD4+T Lymphocyte Imbalance, Metainflammation, and Aggravates Type 2 Diabetes in Murine Model. FRONTIERS IN IMMUNOLOGY, v. 11, . (12/10395-0, 13/08216-2)
SILVA, CASSIA R.; MELO, BRUNO M. S.; SILVA, JAQUELINE R.; LOPES, ALEXANDRE H.; PEREIRA, JANAINA A.; CECILIO, NERRY T.; BERLINK, JONILSON; SOUZA, GIOVANI G.; LUCAS, GUILHERME; VOGL, THOMAS; et al. S100A9 plays a pivotal role in a mouse model of herpetic neuralgia via TLR4/TNF pathway. BRAIN BEHAVIOR AND IMMUNITY, v. 88, p. 353-362, . (13/08216-2, 11/19670-0)
BRANDAO, W. N.; DE OLIVEIRA, M. G.; ANDREONI, R. T.; NAKAYA, H.; FARIAS, A. S.; PERON, J. P. S.. Neuroinflammation at single cell level: What is new?. Journal of Leukocyte Biology, v. 108, n. 4, p. 9-pg., . (17/22504-1, 13/08216-2, 18/14933-2, 19/06372-3, 17/21363-5, 17/26170-0, 12/19278-6, 17/50137-3, 18/21934-5)
BORGHI, SERGIO M.; FATTORI, VICTOR; CARVALHO, THACYANA T.; TATAKIHARA, VERA L. H.; ZANINELLI, TIAGO H.; PINHO-RIBEIRO, FELIPE A.; FERRAZ, CAMILA R.; STAURENGO-FERRARI, LARISSA; CASAGRANDE, RUBIA; PAVANELLI, WANDER R.; et al. Experimental Trypanosoma cruzi Infection Induces Pain in Mice Dependent on Early Spinal Cord Glial Cells and NF kappa B Activation and Cytokine Production. FRONTIERS IN IMMUNOLOGY, v. 11, . (13/08216-2)
LOPES, MARIA ISABEL; BONJORNO, LETICIA P.; GIANNINI, MARCELA C.; AMARAL, NATALIA B.; MENEZES, PAMELLA INDIRA; DIB, SAULO MUSSE; GIGANTE, SAMARA LIBICH; BENATTI, MAIRA N.; REZEK, UEBE C.; EMRICH-FILHO, LAERTE L.; et al. Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial. RMD OPEN, v. 7, n. 1, . (13/08216-2, 20/05601-6, 20/05288-6, 20/04964-8)
SILVA, MARIA CLAUDIA; MEDINA, TIAGO DA SILVA; FUZO, CARLOS ALESSANDRO; DIAS, FABRICIO CESAR; FREITAS-CASTRO, FELIPE; FUKUTANI, KIYOSHI FERREIRA; DONADI, EDUARDO ANTONIO; CUNHA-NETO, EDECIO; CUNHA, THIAGO MATTAR; SILVA, JOAO SANTANA. Polymorphism in the catalytic subunit of the PI3K gamma gene is associated with Trypanosoma cruzi-induced chronic chagasic cardiomyopathy. INFECTION GENETICS AND EVOLUTION, v. 88, . (18/20130-0, 13/08216-2)
KANASHIRO, ALEXANDRE; DE LUCENA LEONCIO, THAIS OLIVEIRA; SCHNEIDER, AYDA HENRIQUES; ALVES, HELIO ROCHA; BASSI, GABRIEL SHIMIZU; VELOSO DUTRA, SABRINA GRAZIANI; CUNHA, FERNANDO DE QUEIROZ; ULLOA, LUIS; MALVAR, DAVID DO CARMO. Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors. PHARMACOLOGICAL REPORTS, v. 71, n. 6, p. 1095-1103, . (11/20343-4, 13/08216-2, 12/04237-2)
ALVES DAMASCENO, LUIS EDUARDO; MARTELOSSI CEBINELLI, GUILHERME CESAR; FERNANDES, MARIANE FONT; NASCIMENTO, DANIELE CARVALHO; PUBLIO, GABRIEL AZEVEDO; RAMIREZ VINOLO, MARCO AURELIO; OLIVEIRA, SERGIO COSTA; SPARWASSER, TIM; CUNHA, THIAGO MATTAR; CUNHA, FERNANDO QUEIROZ; et al. STING is an intrinsic checkpoint inhibitor that restrains the T(H)17 cell pathogenic program. CELL REPORTS, v. 39, n. 8, p. 15-pg., . (19/15070-0, 20/04170-1, 18/17542-4, 13/08216-2)
SARAIVA, ANDRE LOPES; PERES, RAPHAEL SANCHES; VERAS, FLAVIO PROTASIO; TALBOT, JHIMMY; DE LIMA, KALIL ALVES; MESQUITA LUIZ, JOAO PAULO; CUNHA, THIAGO MATTAR; LOUZADA-JUNIOR, PAULO; CUNHA, FERNANDO QUEIROZ; ALVES-FILHO, JOSE CARLOS. Citrullinated human fibrinogen triggers arthritis through an inflammatory response mediated by IL-23/IL-17 immune axis. International Immunopharmacology, v. 101, p. 8-pg., . (13/08216-2, 11/12671-1)
PRADO, DOUGLAS SILVA; VERAS, FLAVIO P.; FERREIRA, RAPHAEL GOMES; DAMASCENO, LUIS EDUARDO ALVES; MELO, PAULO HENRIQUE; ZAMBONI, DARIO SIMOES; CUNHA, THIAGO MATTAR; CUNHA, FERNANDO QUEIROZ; ALVES-FILHO, JOSE CARLOS. NLRP12 controls arthritis severity by acting as a checkpoint inhibitor of Th17 cell differentiation. FASEB JOURNAL, v. 34, n. 8, . (13/08216-2, 16/05377-3)
BORGES, VANESSA DE FATIMA; GALANT, LETICIA SELINGER; KANASHIRO, ALEXANDRE; CASTANHEIRA, FERNANDA VARGAS E SILVA; MONTEIRO, VALTER VINICIUS SILVA; DUARTE, DIEGO ANGELO; RODRIGUES, FILIPE CAMARGO; SILVA, CAMILA MEIRELLES DE SOUZA; SCHNEIDER, AYDA HENRIQUES; CEBINELLI, GUILHERME CESAR MARTELOSSI; et al. FK506 impairs neutrophil migration that results in increased polymicrobial sepsis susceptibility. Inflammation Research, v. 72, n. 2, p. 13-pg., . (17/18264-5, 13/08216-2, 20/08109-5)
HIROKI, CARLOS H.; TOLLER-KAWAHISA, JULIANA E.; FUMAGALLI, MARCILIO J.; COLON, DAVID F.; FIGUEIREDO, LUIZ T. M.; FONSECA, BENDITO A. L. D.; FRANCA, RAFAEL F. O.; CUNHA, FERNANDO Q.. Neutrophil Extracellular Traps Effectively Control Acute Chikungunya Virus Infection. FRONTIERS IN IMMUNOLOGY, v. 10, . (13/08216-2, 11/19670-0)
ALVES DAMASCENO, LUIS EDUARDO; PRADO, DOUGLAS SILVA; VERAS, FLAVIO PROTASIO; FONSECA, MIRIAM M.; TOLLER-KAWAHISA, JULIANA E.; ROSA, MARCOS HENRIQUE; PUBLIO, GABRIEL AZEVEDO; MARTINS, TIMNA VARELA; RAMALHO, FERNANDO S.; WAISMAN, ARI; et al. PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation. JOURNAL OF EXPERIMENTAL MEDICINE, v. 217, n. 10, . (13/08216-2, 16/05377-3, 17/01714-8, 18/23910-6, 16/10280-9)
FACHIM, HELENE A.; LOUREIRO, CAMILA M.; CORSI-ZUELLI, FABIANA; SHUHAMA, ROSANA; LOUZADA, JR., PAULO; MENEZES, PAULO ROSSI; DALTON, CAROLINE F.; DEL-BEN, CRISTINA MARTA; REYNOLDS, GAVIN P.. GRIN2B promoter methylation deficits in early-onset schizophrenia and its association with cognitive function. Epigenomics, v. 11, n. 4, p. 401-410, . (12/05178-0, 12/17626-7, 16/12195-9, 13/11167-3, 13/08216-2, 17/17480-6, 15/02948-7)
DA COSTA, RAFAEL M.; RODRIGUES, DANIEL; PEREIRA, CAMILA A.; SILVA, JOSIANE F.; ALVES, JULIANO V.; LOBATO, NUBIA S.; TOSTES, RITA C.. Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases. FRONTIERS IN PHARMACOLOGY, v. 10, . (13/08216-2)
SPILLER, FERNANDO; FORMIGA, RODRIGO OLIVEIRA; DA SILVA COIMBRA, JONATHAN FERNANDES; ALVES-FILHO, JOSE CARLOS; CUNHA, THIAGO MATTAR; CUNHA, FERNANDO QUEIROZ. Targeting nitric oxide as a key modulator of sepsis, arthritis and pain. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, v. 89, p. 32-40, . (13/08216-2, 12/04132-6)
PEREIRA, CAMILA A.; CARNEIRO, FERNANDO S.; MATSUMOTO, TAKAYUKI; TOSTES, RITA C.. Bonus Effects of Antidiabetic Drugs: Possible Beneficial Effects on Endothelial Dysfunction, Vascular Inflammation and Atherosclerosis. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, v. 123, n. 5, p. 523-538, . (13/08216-2)
WANDERLEY, CARLOS W.; COLON, DAVID F.; LUIZ, JOAO PAULO M.; OLIVEIRA, FRANCISCO F.; VIACAVA, PAULA R.; LEITE, CAIO A.; PEREIRA, JANAINA A.; SILVA, CAMILA M.; SILVA, CASSIA R.; SILVA, RANGEL L.; et al. Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner. Cancer Research, v. 78, n. 20, p. 5891-5900, . (13/08216-2)
GONZALEZ-DIAS, PATRICIA; LEE, EVA K.; SORGI, SARA; DE LIMA, DIOGENES S.; URBANSKI, ALYSSON H.; SILVEIRA, EDUARDO LV; NAKAYA, HELDER I.. Methods for predicting vaccine immunogenicity and reactogenicity. HUMAN VACCINES & IMMUNOTHERAPEUTICS, v. 16, n. 2, . (13/08216-2, 18/21934-5, 18/14933-2)
KUSUDA, RICARDO; CARREIRA, ELEONORA UCHOA; ULLOA, LUIS; CUNHA, FERNANDO QUEIROZ; KANASHIRO, ALEXANDRE; CUNHA, THIAGO MATTAR. Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway. Brain Research, v. 1727, . (12/23846-0, 13/08216-2, 11/20343-4, 10/16823-8)
SILVA, JOSIANE FERNANDES; OLIVON, VANIA C.; MESTRINER, FABIOLA LESLIE A. C.; ZANOTTO, CAMILA ZILIOTTO; FERREIRA, RAPHAEL GOMES; FERREIRA, NATHANNE SANTOS; SILVA, CARLOS ALBERTO AGUIAR; LUIZ, JOAO PAULO MESQUITA; ALVES, JULIANO VILELA; FAZAN, RUBENS; et al. Acute Increase in O-GlcNAc Improves Survival in Mice With LPS-Induced Systemic Inflammatory Response Syndrome. FRONTIERS IN PHYSIOLOGY, v. 10, . (13/08216-2, 16/16207-1)
SILVA CASTANHEIRA, FERNANDA V. E; BORGES, VANESSA; SONEGO, FABIANE; KANASHIRO, ALEXANDRE; DONATE, PAULA B.; MELO, PAULO H.; PALLAS, KENNETH; RUSSO, REMO C.; AMARAL, FLAVIO A.; TEIXEIRA, MAURO M.; et al. THE ATYPICAL CHEMOKINE RECEPTOR ACKR2 IS PROTECTIVE AGAINST SEPSIS. Shock, v. 49, n. 6, p. 682-689, . (13/08216-2, 11/19670-0)
SCHNEIDER, AYDA HENRIQUES; KANASHIRO, ALEXANDRE; VELOSO DUTRA, SABRINA GRAZIANI; DE SOUZA, RAQUEL DO NASCIMENTO; VERAS, FLAVIO PROTASIO; CUNHA, FERNANDO DE QUEIROZ; ULLOA, LUIS; MECAWI, ANDRE SOUZA; REIS, LUIS CARLOS; MALVARA, DAVID DO CARMO. Estradiol replacement therapy regulates innate immune response in ovariectomized arthritic mice. International Immunopharmacology, v. 72, p. 504-510, . (11/20343-4, 13/08216-2, 12/04237-2)
SOUZA, MARIA C.; FONSECA, DENISE M.; KANASHIRO, ALEXANDRE; BENEVIDES, LUCIANA; MEDINA, TIAGO S.; DIAS, MURILO S.; ANDRADE, WARRISON A.; BONFA, GIULIANO; SILVA, MARCONDES A. B.; GOZZI, ALINE; et al. Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v. 7, . (13/08216-2)
MASCARENHAS, DANIELLE P. A.; ZAMBONI, DARIO S.. Inflammasome biology taught by Legionella pneumophila. Journal of Leukocyte Biology, v. 101, n. 4, p. 841-849, . (14/50268-2, 13/08216-2, 14/04684-4, 14/00794-0)
BENEVIDES, LUCIANA; COSTA, RENATA SESTI; TAVARES, LUCAS ALVES; RUSSO, MOMTCHILO; MARTINS, GISLAINE A.; DA SILVA, LUIS LAMBERTI P.; KARLA ARRUDA, L.; CUNHA, FERNANDO Q.; CARREGARO, VANESSA; SILVA, JOAO SANTANA. B lymphocyte-induced maturation protein 1 controls T(H)9 cell development, IL-9 production, and allergic inflammation. Journal of Allergy and Clinical Immunology, v. 143, n. 3, p. 1119+, . (13/08216-2)
SANTA-CECILIA, V, FLAVIA; FERREIRA, DAVID W.; GUIMARAES, RAFAELA M.; CECILIO, NERRY T.; FONSECA, MIRIAM M.; LOPES, ALEXANDRE H.; DAVOLI-FERREIRA, MARCELA; KUSUDA, RICARDO; SOUZA, GUILHERME R.; NACHBUR, UELI; et al. The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development. Pain, v. 160, n. 1, p. 102-116, . (13/08216-2, 11/19670-0)
SILVA, RANGEL L.; SILVEIRA, GABRIELA T.; WANDERLEI, CARLOS W.; CECILIO, NERRY T.; MAGANIN, ALEXANDRE G. M.; FRANCHIN, MARCELO; MARQUES, LUCAS M. M.; LOPES, NORBERTO P.; CRIPPA, JOSE A.; GUIMARAES, FRANCISCO S.; et al. DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A(2A) receptor. Toxicology and Applied Pharmacology, v. 368, p. 63-71, . (13/08216-2)
CARLOS, DANIELA; COSTA, FREDERICO R. C.; PEREIRA, CAMILA A.; ROCHA, FERNANDA A.; YAOCHITE, JULIANA N. U.; OLIVEIRA, GABRIELA G.; CARNEIRO, FERNANDO S.; TOSTES, RITA C.; RAMOS, SIMONE G.; ZAMBONI, DARIO S.; et al. Mitochondrial Dna activates the nlrP3 inflammasome and Predisposes to Type 1 Diabetes in Murine Model. FRONTIERS IN IMMUNOLOGY, v. 8, . (12/10395-0, 13/08216-2)
PERES, RAPHAEL S.; SANTOS, GABRIELA B.; CECILIO, NERRY T.; JABOR, VALQURIA A. P.; NIEHUES, MICHAEL; TORRES, BRUNA G. S.; BUQUI, GABRIELA; SILVA, CARLOS H. T. P.; DALLA COSTA, TERESA; LOPES, NORBERTO P.; et al. Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis. ARTHRITIS RESEARCH & THERAPY, v. 19, . (13/08216-2, 12/20990-2, 09/54014-7, 12/25075-0, 14/50265-3)
TREVELIN, SILVIA C.; CARLOS, DANIELA; BERETTA, MATTEO; DA SILVA, JOAO S.; CUNHA, FERNANDO Q.. Diabetes Mellitus and Sepsis: A Challenging Association. Shock, v. 47, n. 3, p. 276-287, . (13/08216-2, 11/03293-3, 11/19670-0, 09/54764-6)
ZARPELON, ANA C.; FATTORI, VICTOR; SOUTO, FABRICIO O.; PINTO, LARISSA G.; PINHO-RIBEIRO, FELIPE A.; RUIZ-MIYAZAWA, KENJI W.; TURATO, WALTER M.; CUNHA, THIAGO M.; DA COSTA, FERNANDO B.; CUNHA, FERNANDO Q.; et al. The Sesquiterpene Lactone, Budlein A, Inhibits Antigen-Induced Arthritis in Mice: Role of NF-kappa B and Cytokines. Inflammation, v. 40, n. 6, p. 2020-2032, . (13/08216-2, 11/19670-0)
FATTORI, VICTOR; HOHMANN, MIRIAM S. N.; ROSSANEIS, ANA C.; MANCHOPE, MARILIA F.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; VERRI, JR., WALDICEU A.. Targeting IL-33/ST2 signaling: regulation of immune function and analgesia. EXPERT OPINION ON THERAPEUTIC TARGETS, v. 21, n. 12, p. 1141-1152, . (13/08216-2, 11/19670-0)
KETELUT-CARNEIRO, NATALIA; GHOSH, SREYA; LEVITZ, STUART M.; FITZGERALD, KATHERINE A.; DA SILVA, JOAO SANTANA. A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1 beta Release in Response to a Pathogenic Fungus. Journal of Infectious Diseases, v. 217, n. 2, p. 329-339, . (13/08216-2, 13/21295-9, 12/14524-9, 14/24503-4)
FRANCHIN, MARCELO; COLON, DAVID F.; CASTANHEIRA, FERNANDA V. S.; DA CUNHA, MARCOS G.; BUENO-SILVA, BRUNO; ALENCAR, SEVERINO M.; CUNHA, THIAGO M.; ROSALEN, PEDRO L.. Vestitol Isolated from Brazilian Red Propolis Inhibits Neutrophils Migration in the Inflammatory Process: Elucidation of the Mechanism of Action. Journal of Natural Products, v. 79, n. 4, p. 954-960, . (12/22378-2, 13/08216-2, 12/01365-0)
MASSAFERA TRISTAO, FABRINE SALES; ROCHA, FERNANDA AGOSTINI; CARLOS, DANIELA; KETELUT-CARNEIRO, NATALIA; SILVA SOUZA, CAMILA OLIVEIRA; MILANEZI, CRISTIANE MARIA; SILVA, JOAO SANTANA. Th17-inducing cytokines IL-6 and IL-23 are crucial for granuloma Formation during experimental Paracoccidioidomycosis. FRONTIERS IN IMMUNOLOGY, v. 8, . (13/08216-2)
MASCARENHAS, DANIELLE P. A.; CERQUEIRA, DAIANE M.; PEREIRA, MARCELO S. F.; CASTANHEIRA, FERNANDA V. S.; FERNANDES, TALITA D.; MANIN, GRAZIELE Z.; CUNHA, LARISSA D.; ZAMBONI, DARIO S.. Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome. PLOS PATHOGENS, v. 13, n. 8, . (13/08216-2, 14/04684-4, 12/09363-6)
LIMA-JUNIOR, DJALMA S.; MINEO, TIAGO W. P.; CALICH, VERA L. G.; ZAMBONI, DARIO S.. Dectin-1 Activation during Leishmania amazonensis Phagocytosis Prompts Syk-Dependent Reactive Oxygen Species Production To Trigger Inflammasome Assembly and Restriction of Parasite Replication. JOURNAL OF IMMUNOLOGY, v. 199, n. 6, p. 2055-2068, . (13/08216-2, 14/04684-4, 13/15994-1)
TEIXEIRA, LARISSA B.; PARREIRAS-E-SILVA, LUCAS T.; BRUDER-NASCIMENTO, THIAGO; DUARTE, DIEGO A.; SIMOES, SARAH C.; COSTA, RAFAEL M.; RODRIGUEZ, DEISY Y.; FERREIRA, PEDRO A. B.; SILVA, CARLOS A. A.; ABRAO, EMILIANA P.; et al. Ang-(1-7) is an endogenous beta-arrestin-biased agonist of the AT(1) receptor with protective action in cardiac hypertrophy. SCIENTIFIC REPORTS, v. 7, . (12/20148-0, 13/08216-2, 15/50086-4)
FRANCHIN, MARCELO; COLON, DAVID F.; DA CUNHA, MARCOS G.; CASTANHEIRA, FERNANDA V. S.; SARAIVA, ANDRE L. L.; BUENO-SILVA, BRUNO; ALENCAR, SEVERINO M.; CUNHA, THIAGO M.; ROSALEN, PEDRO L.. Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide and IL-6. SCIENTIFIC REPORTS, v. 6, . (12/22378-2, 13/08216-2, 12/01365-0)
KETELUT-CARNEIRO, NATALIA; SILVA, GRACE KELLY; ROCHA, FERNANDA AGOSTINI; MILANEZI, CRISTIANE MARIA; CAVALCANTI-NETO, FLORENCIO FIGUEIREDO; ZAMBONI, DARIO SIMOES; SILVA, JOAO SANTANA. IL-18 Triggered by the Nlrp3 Inflammasome Induces Host Innate Resistance in a Pulmonary Model of Fungal Infection. JOURNAL OF IMMUNOLOGY, v. 194, n. 9, p. 4507-4517, . (13/08216-2, 13/21295-9, 12/14524-9)
ZARPELON, ANA C.; RODRIGUES, FRANCIELLE C.; LOPES, ALEXANDRE H.; SOUZA, GUILHERME R.; CARVALHO, THACYANA T.; PINTO, LARISSA G.; XU, DAMO; FERREIRA, SERGIO H.; ALVES-FILHO, JOSE C.; MCINNES, IAIN B.; et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB JOURNAL, v. 30, n. 1, p. 54-65, . (13/08216-2, 11/19670-0)
SANTA-CECILIA, FLAVIA V.; SOCIAS, BENJAMIN; OUIDJA, MOHAND O.; SEPULVEDA-DIAZ, JULIA E.; ACUNA, LEONARDO; SILVA, RANGEL L.; MICHEL, PATRICK P.; DEL-BEL, ELAINE; CUNHA, THIAGO M.; RAISMAN-VOZARI, RITA. Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways. NEUROTOXICITY RESEARCH, v. 29, n. 4, p. 447-459, . (13/08216-2, 11/19670-0)
DA COSTA, RAFAEL MENEZES; NEVES, KARLA BIANCA; MESTRINER, FABIOLA LESLIE; LOUZADA-JUNIOR, PAULO; BRUDER-NASCIMENTO, THIAGO; TOSTES, RITA C.. TNF-alpha induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice. CARDIOVASCULAR DIABETOLOGY, v. 15, . (13/08216-2)
NASCIMENTO, MANUELA S. L.; FERREIRA, MARCELA D.; QUIRINO, GUSTAVO F. S.; MARUYAMA, SANDRA R.; KRISHNASWAMY, JAYENDRA K.; LIU, DONG; BERLINK, JONILSON; FONSECA, DENISE M.; ZAMBONI, DARIO S.; CARREGARO, VANESSA; et al. NOD2-RIP2-Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis. Journal of Infectious Diseases, v. 214, n. 11, p. 1647-1657, . (13/08216-2)
MEDINA, TIAGO SILVA; OLIVEIRA, GABRIELA GONCALVES; SILVA, MARIA CLAUDIA; DAVID, BRUNA ARAUJO; SILVA, GRACE KELLY; FONSECA, DENISE MORAIS; SESTI-COSTA, RENATA; FRADE, AMANDA FARAGE; BARON, MONIQUE ANDRADE; IANNI, BARBARA; et al. Ebi3 Prevents Trypanosoma cruzi-Induced Myocarditis by Dampening IFN-gamma-Driven Inflammation. FRONTIERS IN IMMUNOLOGY, v. 8, . (13/08216-2, 12/14524-9)
GONCALVES, AUGUSTO V.; MARGOLIS, SHALLY R.; QUIRINO, GUSTAVO F. S.; MASCARENHAS, DANIELLE P. A.; RAUCH, ISABELLA; NICHOLS, RANDILEA D.; ANSALDO, EDUARD; FONTANA, MARY F.; VANCE, RUSSELL E.; ZAMBONI, DARIO S.. Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila. PLOS PATHOGENS, v. 15, n. 6, . (13/08216-2, 14/04684-4)
SOARES-SCHANOSKI, ALESSANDRA; BAPTISTA CRUZ, NATALIA; DE CASTRO-JORGE, LUIZA ANTUNES; HOMEM DE CARVALHO, RENAN VILLANOVA; DOS SANTOS, CLIOMAR ALVES; DA ROS, NANCY; OLIVEIRA, URSULA; COSTA, DANUZA DUARTE; SIMOES DOS SANTOS, CECILIA LUIZA; CUNHA, MARIELTON DOS PASSOS; et al. Systems analysis of subjects acutely infected with the Chikungunya virus. PLOS PATHOGENS, v. 15, n. 6, . (12/19278-6, 13/07467-1, 15/25055-8, 13/08216-2, 16/08204-2, 17/50137-3)
SARAIVA, ANDRE L.; VERAS, FLAVIO P.; PERES, RAPHAEL S.; TALBOT, JHIMMY; DE LIMA, KALIL A.; LUIZ, JOAO P.; CARBALLIDO, JOSE M.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; RYFFEL, BERNHARD; et al. Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of T(h)17 cells in the lymph nodes. FASEB JOURNAL, v. 32, n. 12, p. 6550-6558, . (13/08216-2, 11/19670-0)
MANCHOPE, MARILIA F.; ARTERO, NAYARA A.; FATTORI, VICTOR; MIZOKAMI, SANDRA S.; PITOL, DIMITRIUS L.; ISSA, JOAO P. M.; FUKADA, SANDRA Y.; CUNHA, THIAGO M.; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; et al. Naringenin mitigates titanium dioxide (TiO2)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NF kappa B. Inflammation Research, v. 67, n. 11-12, p. 997-1012, . (13/08216-2, 11/19670-0)
DE LIMA, KALIL ALVES; DONATE, PAULA BARBIM; TALBOT, JHIMMY; DAVOLI-FERREIRA, MARCELA; PERES, RAPHAEL SANCHES; CUNHA, THIAGO MATTAR; ALVES-FILHO, JOSE CARLOS; CUNHA, FERNANDO QUEIROZ. TGF beta 1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of T(H)17 cells by an AHR-independent mechanism. CELL DEATH & DISEASE, v. 9, . (13/08216-2, 16/05013-1, 13/04942-0)
LOUREIRO, CAMILA MARCELINO; FACHIM, HELENE APARECIDA; CORSI-ZUELLI, FABIANA; SHUHAMA, ROSANA; JOCA, SAMIA; MENEZES, PAULO ROSSI; DALTON, CAROLINE F.; DEL-BEN, CRISTINA MARTA; LOUZADA-JUNIOR, PAULO; REYNOLDS, GAVIN P.. Epigenetic-mediated N-methyl-D-aspartate receptor changes in the brain of isolated reared rats. Epigenomics, v. 12, n. 22, . (13/08216-2, 16/12195-9, 12/05178-0, 13/11167-3, 12/17626-7, 15/02948-7, 19/13229-2, 17/00624-5)
PINEROS, ANNIE R.; DE LIMA, MIKHAEL H. F.; RODRIGUES, TAMARA; GEMBRE, ANA FLAVIA; BERTOLINI, THAIS B.; FONSECA, MIRIAM D.; BERRETTA, ANDRESA A.; RAMALHO, LEANDRA N. Z.; CUNHA, FERNANDO Q.; HORI, JULIANA I.; et al. Green propolis increases myeloid suppressor cells and CD4(+) Foxp3(+) cells and reduces Th2 inflammation in the lungs after allergen exposure. Journal of Ethnopharmacology, v. 252, . (13/08216-2, 11/09702-2, 15/15963-4)
SACRAMENTO, LAIS AMORIM; BENEVIDES, LUCIANA; MARUYAMA, SANDRA REGINA; TAVARES, LUCAS; FUKUTANI, KIYOSHI FERREIRA; FRANCOZO, MARCELA; SPARWASSER, TIM; CUNHA, FERNANDO QUEIROZ; ALMEIDA, ROQUE PACHECO; DA SILVA, JOAO SANTANA; et al. TLR4 abrogates the Th1 immune response through IRF1 and IFN-beta to prevent immunopathology during L. infantum infection. PLOS PATHOGENS, v. 16, n. 3, . (15/12526-2, 13/08216-2, 17/04347-6, 12/14524-9)
KANASHIRO, ALEXANDRE; FRANCHIN, MARCELO; BASSI, GABRIEL SHIMIZU; REIS SANTANA, DENIS AUGUSTO; CUNHA, THIAGO MATTAR; CUNHA, FERNANDO QUEIROZ; ULLOA, LUIS; RODRIGUES, GERSON JONATHAN. Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation. FUNDAMENTAL & CLINICAL PHARMACOLOGY, v. 32, n. 2, p. 155-162, . (13/08216-2, 12/04237-2, 11/20343-4)
ARIAS-CARRASCO, RAUL; GIDDALURU, JEEVAN; CARDOZO, LUCAS E.; MARTINS, FELIPE; MARACAJA-COUTINHO, VINICIUS; NAKAYA, HELDER I.. OUTBREAK: a user-friendly georeferencing online tool for disease surveillance. Biological Research, v. 54, n. 1, . (18/14933-2, 13/08216-2, 19/16419-7, 18/21934-5, 17/50137-3)
GOMES, ELLEN; ROGERIO, LUANA APARECIDA; TAKAMIYA, NAYORE TAMIE; TORRES, CAROLINE; DA SILVA, JOAO SANTANA; ALMEIDA, ROQUE PACHECO; MARUYAMA, SANDRA REGINA. Dataset of dual RNA-seq mapping in visceral leishmaniasis: Inquiry on parasite transcripts in human blood transcriptome upon Leishmania infantum infection. DATA IN BRIEF, v. 46, p. 7-pg., . (16/20258-0, 17/16328-6, 21/12464-8, 22/01525-9, 20/14011-8, 13/08216-2, 21/10358-6)
OLIVEIRA, ISADORA; COSTA, VICTOR; VERAS, FLAVIO; FERREIRA, ISABELA; CUNHA, FERNANDO; CUNHA, THIAGO; MONTEIRO, WUELTON; ARANTES, ELIANE; PUCCA, MANUELA. A Promising Biomolecule Able to Degrade Neutrophil Extracellular Traps: CdcPDE, a Rattlesnake Phosphodiesterase. TOXINS, v. 15, n. 1, p. 5-pg., . (20/13176-3, 19/10173-6, 13/08216-2)
CAMILA MARCELINO LOUREIRO; FABIANA CORSI-ZUELLI; HELENE APARECIDA FACHIM; ROSANA SHUHAMA; ADRIELLE MARTINS DE OLIVEIRA; PAULO ROSSI MENEZES; CAROLINE F. DALTON; PAULO LOUZADA-JUNIOR; SINTIA IOLE BELANGERO; FERNANDA COELI-LACCHINI; et al. Lifetime cannabis use and childhood trauma increase risk of psychosis in carriers of CNR1 genetic variants: findings from the STREAM study. Revista Brasileira de Psiquiatria, v. 45, n. 3, p. 226-235, . (12/05178-0, 19/13229-2, 17/00624-5, 15/02948-7, 20/15752-1, 13/08216-2, 21/07448-3, 13/11167-3)
ALMEIDA, CELLYNE R.; LIMA, JULIA F.; MACHADO, MIRELE R.; ALVES, JULIANO V.; COUTO, ARIEL E. S.; CAMPOS, LIGIA C. B.; AVILA-MESQUITA, CAROLINA D.; AUXILIADORA-MARTINS, MARIA; BECARI, CHRISTIANE; LOUZADA-JUNIOR, PAULO; et al. Inhibition of IL-6 signaling prevents serum-induced umbilical cord artery dysfunction from patients with severe COVID-19. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, v. 324, n. 4, p. 11-pg., . (13/08216-2)
ANIBAL SILVA, CONCEICAO ELIDIANNE; GUIMARAES, RAFAELA MANO; CUNHA, THIAGO MATTAR. Sensory neuron-associated macrophages as novel modulators of neuropathic pain. PAIN REPORTS, v. 6, n. 1, . (20/05446-0, 13/08216-2, 19/13829-0, 17/50419-9)
DIAS FLORENCIO, KATHARINE GURGEL; EDSON, EVELLINE ARAUJO; DA SILVA FERNANDES, KEILLA SANTANA; MESQUITA LUIZ, JOAO PAULO; LIMA PINTO, FRANCISCO DAS CHAGAS; LOIOLA PESSOA, OTILIA DEUSDENIA; CUNHA, FERNANDO DE QUEIROZ; MACHADO-NETO, JOAO AGOSTINHO; WILKE, DIEGO VERAS. Chromomycin A(5) induces bona fide immunogenic cell death in melanoma. FRONTIERS IN IMMUNOLOGY, v. 13, p. 19-pg., . (13/08216-2, 19/23864-7)
SILVA, CAMILA MEIRELLES S.; WANDERLEY, CARLOS WAGNER S.; VERAS, FLAVIO PROTASIO; GONCALVES, AUGUSTO VELOSO; FERNANDES LIMA, MIKHAEL HARUO; TOLLER KAWAHISA, JULIANA ESCHER; GOMES, GIOVANNI FREITAS; NASCIMENTO, DANIELE CARVALHO; SILVA MONTEIRO, VALTER V.; PAIVA, ISADORA MARQUES; et al. Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology. Critical Care, v. 26, n. 1, p. 16-pg., . (13/08216-2)
GUIMARES, RAFAELA M.; ANIBAL-SILVA, CONCEICO E.; DAVOLI-FERREIRA, MARCELA; GOMES, FRANCISCO ISAAC F.; MENDES, ATLANTE; CAVALLINI, MARIA C. M.; FONSECA, MIRIAM M.; DAMASCENO, SAMARA; ANDRADE, LARISSA P.; COLONNA, MARCO; et al. Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling. eLIFE, v. 12, p. 26-pg., . (13/08216-2)
CARREGARO, VANESSA; NAPIMOGA, MARCELO H.; PERES, RAPHAEL S.; BENEVIDES, LUCIANA; SACRAMENTO, LAIS AMORIM; PINTO, LARISSA G.; GRESPAN, RENATA; CUNHA, THIAGO M.; DA SILVA, JOAO SANTANA; CUNHA, FERNANDO Q.. Therapeutic Treatment of Arthritic Mice with 15-Deoxy Delta(12,14)-Prostaglandin J(2) (15d-PGJ(2)) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4(+)CD25(-)FOXP3(+) Cells. Mediators of Inflammation, . (13/08216-2)
CUNHA, LARISSA D.; ZAMBONI, DARIO S.. Recognition of Legionella pneumophila nucleic acids by innate immune receptors. Microbes and Infection, v. 16, n. 12, SI, p. 985-990, . (13/08216-2, 14/04684-4, 12/09363-6)
COLON, DAVID F.; WANDERLEY, CARLOS W.; FRANCHIN, MARCELO; SILVA, CAMILA M.; HIROKI, CARLOS H.; CASTANHEIRA, FERNANDA V. S.; DONATE, PAULA B.; LOPES, ALEXANDRE H.; VOLPON, LEILA C.; KAVAGUTI, SILVIA K.; et al. Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis. CRITICAL CARE, v. 23, . (13/08216-2, 11/19670-0)
LOURENCO-GONZALEZ, YURI; FATTORI, VICTOR; DOMICIANO, TALITA P.; ROSSANEIS, ANA C.; BORGHI, SERGIO M.; ZANINELLI, TIAGO H.; BERNARDY, CATIA C. F.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; et al. Repurposing of the Nootropic Drug Vinpocetine as an Analgesic and Anti-Inflammatory Agent: Evidence in a Mouse Model of Superoxide Anion-Triggered Inflammation. Mediators of Inflammation, . (13/08216-2, 11/19670-0)
BECARI, CHRISTIANE; SILVA, MARCONDES A. B.; DURAND, MARINA T.; PRADO, CIBELE M.; OLIVEIRA, EDUARDO B.; RIBEIRO, MAURICIO S.; SALGADO, HELIO C.; SALGADO, MARIA CRISTINA O.; TOSTES, RITA C.. Elastase-2, an angiotensin II-generating enzyme, contributes to increased angiotensin II in resistance arteries of mice with myocardial infarction. British Journal of Pharmacology, v. 174, n. 10, SI, p. 1104-1115, . (13/08216-2)
GOMES, FRANCISCO ISAAC F.; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.. Peripheral nitric oxide signaling directly blocks inflammatory pain. Biochemical Pharmacology, v. 176, n. SI, . (13/08216-2, 19/14285-3)
ANDRADE, WARRISON A.; ZAMBONI, DARIO S.. NLRC4 biology in immunity and inflammation. Journal of Leukocyte Biology, . (13/08216-2, 18/14398-0, 19/11342-6, 14/04684-4)
AGUIAR, RENATO S.; POHL, FABIO; MORAIS, GUILHERME L.; NOGUEIRA, FABIO C. S.; DE CARVALHO, JOSEANE B.; GUIDA, LETICIA; ARGE, LUIS W. P.; MELO, ADRIANA; MOREIRA, MARIA E. L.; CUNHA, DANIELA P.; et al. Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome. Science Signaling, v. 13, n. 635, . (13/08216-2, 12/19278-6, 18/21934-5, 17/50137-3, 18/14933-2)
PERON, J. P. S.; NAKAYA, I, H.; SCHLINDWEIN, M. A. M.; GONCALVES, M. V. M.. COVID-19 Pandemic and Dysbiosis: Can the Ivermectin Hysteria Lead to an Increase of Autoimmune Neuroinflammatory Diseases?. CRITICAL REVIEWS IN IMMUNOLOGY, v. 40, n. 6, SI, p. 537-542, . (17/22504-1, 18/14933-2, 12/19278-6, 13/08216-2, 18/21934-5, 19/06372-3, 17/21363-5)
NEVES, KARLA BIANCA; MONTEZANO, AUGUSTO CESAR; ALVES-LOPES, RHEURE; BRUDER-NASCIMENTO, THIAGO; COSTA, RAFAEL MENEZES; COSTA, ROBERTO S.; TOUYZ, RHIAN M.; TOSTES, RITA C.. Upregulation of Nrf2 and Decreased Redox Signaling Contribute to Renoprotective Effects of Chemerin Receptor Blockade in Diabetic Mice. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 19, n. 8, . (13/08216-2, 15/01630-3, 12/13144-8)
ZUCCOLI, GIULIANA S.; REIS-DE-OLIVEIRA, GUILHERME; GARBES, BRUNA; FALKAI, PETER; SCHMITT, ANDREA; NAKAYA, I, HELDER; MARTINS-DE-SOUZA, DANIEL. Linking proteomic alterations in schizophrenia hippocampus to NMDAr hypofunction in human neurons and oligodendrocytes. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, . (17/25588-1, 19/00098-7, 18/01410-1, 13/08216-2, 18/14666-4, 12/19278-6, 17/50137-3)
LUIZ, JOAO PAULO M.; TOLLER-KAWAHISA, JULIANA E.; VIACAVA, PAULA R.; NASCIMENTO, DANIELE C.; PEREIRA, PRISCILLA T.; SARAIVA, ANDRE L.; PRADO, DOUGLAS S.; LEBERT, MARC; GIURISATO, EMANUELE; TOURNIER, CATHY; et al. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology, . (17/20692-5, 13/08216-2, 11/12671-1, 17/01714-8, 16/05377-3)
DAL-SECCO, DANIELA; DALBO, SILVIA; LAUTHERBACH, NATALIA E. S.; GAVA, FABIO N.; CELES, MARA R. N.; BENEDET, PATRICIA O.; SOUZA, ADRIANA H.; AKINAGA, JULIANA; LIMA, VANESSA; SILVA, KATIUSSIA P.; et al. Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G protein receptor kinase. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 313, n. 1, p. H149-H163, . (13/08216-2, 09/54010-1)
BERTOZZI, MARIANA M.; ROSSANEIS, ANA C.; FATTORI, VICTOR; LONGHI-BALBINOT, DANIELA T.; FREITAS, ANDRESSA; CUNHA, FERNANDO Q.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; CASAGRANDE, RUBIA; VERRI, JR., WALDICEU A.. Diosmin reduces chronic constriction injury-induced neuropathic pain in mice. Chemico-Biological Interactions, v. 273, p. 180-189, . (13/08216-2, 11/19670-0)
SACRAMENTO, LAIS A.; DA COSTA, JESSICA L.; DE LIMA, MIKHAEL H. F.; SAMPAIO, PEDRO A.; ALMEIDA, ROQUE P.; CUNHA, FERNANDO Q.; SILVA, JOAO S.; CARREGARO, VANESSA. Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection. FRONTIERS IN MICROBIOLOGY, v. 8, . (15/12526-2, 13/08216-2)
RUSSO, PEDRO S. T.; FERREIRA, GUSTAVO R.; CARDOZO, LUCAS E.; BUERGER, MATHEUS C.; ARIAS-CARRASCO, RAUL; MARUYAMA, SANDRA R.; HIRATA, THIAGO D. C.; LIMA, DIOGENES S.; PASSOS, FERNANDO M.; FUKUTANI, KIYOSHI F.; et al. CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses. BMC Bioinformatics, v. 19, . (15/25825-8, 13/08216-2, 12/19278-6, 14/19323-7, 14/24162-2, 17/05762-7, 15/20897-0)
CARREGARO, VANESSA; RIBEIRO, JOSE M.; VALENZUELA, JESUS G.; SOUZA-JUNIOR, DJALMA L.; COSTA, DIEGO L.; OLIVEIRA, CARLO J. F.; SACRAMENTO, LAIS A.; NASCIMENTO, MANUELA S. L.; MILANEZI, CRISTIANE M.; CUNHA, FERNANDO Q.; et al. Nucleosides Present on Phlebotomine Saliva Induce Immunossuppression and Promote the Infection Establishment. PLoS Neglected Tropical Diseases, v. 9, n. 4, . (13/08216-2)
SILVA, MARIA C.; DAVOLI-FERREIRA, MARCELA; MEDINA, TIAGO S.; SESTI-COSTA, RENATA; SILVA, GRACE K.; LOPES, CARLA D.; CARDOZO, LUCAS E.; GAVA, FABIO N.; LYRONI, KONSTANTINA; DIAS, FABRICIO C.; et al. Canonical PI3K gamma signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. NATURE COMMUNICATIONS, v. 9, . (13/08216-2, 12/14524-9, 11/09488-0)
ALVES-LOPES, RHEURE; NEVES, KARLA B.; MONTEZANO, AUGUSTO C.; HARVEY, ADAM; CARNEIRO, FERNANDO S.; TOUYZ, RHIAN M.; TOSTES, RITA C.. Internal Pudental Artery Dysfunction in Diabetes Mellitus Is Mediated by NOX1-Derived ROS-, Nrf2-, and Rho Kinase-Dependent Mechanisms. Hypertension, v. 68, n. 4, p. 1056-1064, . (12/12178-6, 13/08216-2)
PUCCA, MANUELA BERTO; CERNI, FELIPE AUGUSTO; CORDEIRO, FRANCIELLE ALMEIDA; PEIGNEUR, STEVE; CUNHA, THIAGO MATTAR; TYTGAT, JAN; ARANTES, ELIANE CANDIANI. Ts8 scorpion toxin inhibits the Kv4.2 channel and produces nociception in vivo. Toxicon, v. 119, p. 244-252, . (12/12954-6, 13/21342-7, 12/13590-8, 13/21329-0, 13/08216-2)
PINTO, LARISSA G.; TALBOT, JHIMMY; PERES, RAPHAEL S.; FRANCA, RAFAEL F.; FERREIRA, SERGIO H.; RYFFEL, BERNHARD; AVES-FILHO, JOSE CARLOS F.; FIGUEIREDO, FLORENCIO; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1 beta production. ARTHRITIS RESEARCH & THERAPY, v. 17, . (13/08216-2, 11/19670-0)
SILVA, MARCONDES A. B.; BRUDER-NASCIMENTO, THIAGO; CAU, STEFANY B. A.; LOPES, RHEURE A. M.; MESTRINER, FABIOLA L. A. C.; FAIS, RAFAEL S.; TOUYZ, RHIAN M.; TOSTES, RITA C.. Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling. FRONTIERS IN PHYSIOLOGY, v. 6, . (13/08216-2, 10/52214-6)
BASSI, GABRIEL S.; BROGNARA, FERNANDA; CASTANIA, JACI A.; TALBOT, JHIMMY; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; ULLOA, LUIS; KANASHIRO, ALEXANDRE; MARTINS DIAS, DANIEL P.; SALGADO, HELIO C.. Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function. BRAIN BEHAVIOR AND IMMUNITY, v. 49, p. 140-147, . (14/15386-4, 13/20549-7, 13/08216-2, 11/20343-4, 12/04237-2)
PRATES, T. P.; TAIRA, T. M.; HOLANDA, M. C.; BIGNARDI, L. A.; SALVADOR, S. L.; ZAMBONI, D. S.; CUNHA, F. Q.; FUKADA, S. Y.. NOD2 Contributes to Porphyromonas gingivalis-induced Bone Resorption. JOURNAL OF DENTAL RESEARCH, v. 93, n. 11, p. 1155-1162, . (11/20736-6, 13/08216-2)
TAMASHIRO, LETICIA FALEIROS; OLIVEIRA, RENE D. R.; OLIVEIRA, RODRIGO; COMINI FROTA, ELIZABETH REGINA; DONADI, EDUARDO ANTONIO; DEL-BEN, CRISTINA MARTA; TEIXEIRA, ANTONIO LUCIO; LOUZADA-JUNIOR, PAULO. Participation of the neutrophin brain-derived neurotrophic factor in neuropsychiatric systemic lupus erythematosus. RHEUMATOLOGY, v. 53, n. 12, p. 2182-2190, . (13/08216-2, 11/19670-0)
FATTORI, VICTOR; BORGHI, SERGIO M.; GUAZELLI, CARLA F. S.; GIROLDO, ANDRESSA C.; CRESPIGIO, JEFFERSON; BUSSMANN, ALLAN J. C.; COELHO-SILVA, LETICIA; LUDWIG, NATASHA G.; MAZZUCO, TANIA L.; CASAGRANDE, RUBIA; et al. Vinpocetine reduces diclofenac-induced acute kidney injury through inhibition of oxidative stress, apoptosis, cytokine production, and NF-kappa B activation in mice. PHARMACOLOGICAL RESEARCH, v. 120, p. 10-22, . (13/08216-2)
PRADA-MEDINA, CESAR A.; FUKUTANI, KIYOSHI F.; KUMAR, NATHELLA PAVAN; GIL-SANTANA, LEONARDO; BABU, SUBASH; LICHTENSTEIN, FLAVIO; WEST, KIM; SIVAKUMAR, SHANMUGAM; MENON, PRADEEP A.; VISWANATHAN, VIJAY; et al. Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications. SCIENTIFIC REPORTS, v. 7, . (13/08216-2)
VERAS, FLAVIO P.; PERES, RAPHAEL S.; SARAIVA, ANDRE L. L.; PINTO, LARISSA G.; LOUZADA-JUNIOR, PAULO; CUNHA, THIAGO M.; PASCHOAL, JONAS A. R.; CUNHA, FERNANDO Q.; ALVES-FILHO, JOSE C.. Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway. SCIENTIFIC REPORTS, v. 5, . (13/08216-2, 09/54014-7, 11/19670-0)
BENEVIDES, LUCIANA; DA FONSECA, DENISE MORAIS; DONATE, PAULA BARBIM; TIEZZI, DANIEL GUIMARAES; DE CARVALHO, DANIEL D.; DE ANDRADE, JURANDYR M.; MARTINS, GISLAINE A.; SILVA, JOAO S.. IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment. Cancer Research, v. 75, n. 18, p. 3788-3799, . (13/08216-2, 12/08240-8, 12/14524-9)
QUADROS, ANDREZA U.; PINTO, LARISSA G.; FONSECA, MIRIAM M.; KUSUDA, RICARDO; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.. Dynamic weight bearing is an efficient and predictable method for evaluation of arthritic nociception and its pathophysiological mechanisms in mice. SCIENTIFIC REPORTS, v. 5, . (13/08216-2, 09/54014-7, 11/19670-0)
PERNOMIAN, LARISSA; DA SILVA, CARLOS H. T. P.. Current basis for discovery and development of aryl hydrocarbon receptor antagonists for experimental and therapeutic use in atherosclerosis. European Journal of Pharmacology, v. 764, p. 118-123, . (14/17740-0, 13/08216-2)
PERNOMIAN, LARISSA; DO PRADO, ALEJANDRO F.; GOMES, MAYARA S.; PERNOMIAN, LAENA; DA SILVA, CARLOS H. T. P.; GERLACH, RAQUEL F.; DE OLIVEIRA, ANA M.. MAS receptors mediate vasoprotective and atheroprotective effects of candesartan upon the recovery of vascular angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS axis functionality. European Journal of Pharmacology, v. 764, p. 173-188, . (14/17740-0, 13/08216-2, 12/00640-7, 12/09019-3)
MOREIRA, JOSIMAR D.; PERNOMIAN, LARISSA; GOMES, MAYARA S.; PERNOMIAN, LAENA; MOREIRA, RAFAEL P.; DO PRADO, ALEJANDRO F.; DA SILVA, CARLOS H. T. P.; DE OLIVEIRA, ANA M.. Acute restraint stress increases carotid reactivity in type-I diabetic rats by enhancing Nox4/NADPH oxidase functionality. European Journal of Pharmacology, v. 765, p. 503-516, . (14/17740-0, 13/08216-2, 11/11205-7)
COSTA, FREDERICO R. C.; FRANCOZO, MARCELA C. S.; DE OLIVEIRA, GABRIELA G.; IGNACIO, ALINE; CASTOLDI, ANGELA; ZAMBONI, DARIO S.; RAMOS, SIMONE G.; CAMARA, NIELS O.; DE ZOETE, MARCEL R.; PALM, NOAH W.; et al. Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset. JOURNAL OF EXPERIMENTAL MEDICINE, v. 213, n. 7, p. 1223-1239, . (12/10395-0, 13/08216-2)
SOUZA, GUILHERME R.; CUNHA, THIAGO M.; SILVA, RANGE L.; LOTUFO, CELINA M.; VERRI, JR., WALDICEU A.; FUNEZ, MANI I.; VILLARREAL, CHRISTIANE F.; TALBOT, JHIMMY; SOUSA, LIRLANDIA P.; PARADA, CARLOS A.; et al. Involvement of nuclear factor kappa B in the maintenance of persistent inflammatory hypernociception. Pharmacology Biochemistry and Behavior, v. 134, p. 49-56, . (13/08216-2, 11/19670-0)
TALBOT, JHIMMY; BIANCHINI, FRANCINE J.; NASCIMENTO, DANILELE C.; OLIVEIRA, RENE D. R.; SOUTO, FABRICIO O.; PINTO, LARISSA G.; PERES, RAPHAEL S.; SILVA, JAQUELINE R.; ALMEIDA, SERGIO C. L.; LOUZADA-JUNIOR, PAULO; et al. CCR2 Expression in Neutrophils Plays a Critical Role in Their Migration Into the Joints in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, v. 67, n. 7, p. 1751-1759, . (13/08216-2, 11/19670-0)
SANT'ANNA, MORENA B.; KUSUDA, RICARDO; BOZZO, TIAGO A.; BASSI, GABRIEL S.; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; FERREIRA, SERGIO H.; SOUZA, GUILHERME R.; CUNHA, THIAGO M.. Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization. SCIENTIFIC REPORTS, v. 6, . (13/08216-2, 11/19670-0)
NEVES, KARLA BIANCA; CAT, AURELIE NGUYEN DINH; ALVES-LOPES, RHEURE; HARVEY, KATIE YATES; DA COSTA, RAFAEL MENEZES; LOBATO, NUBIA SOUZA; MONTEZANO, AUGUSTO CESAR; DE OLIVEIRA, ANA MARIA; TOUYZ, RHIAN M.; TOSTES, RITA C.. Chemerin receptor blockade improves vascular function in diabetic obese mice via redox-sensitive and Akt-dependent pathways. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 315, n. 6, p. H1851-H1860, . (13/08216-2, 15/01630-3, 12/13144-8)
JOCHEMS, SIMON P.; MARCON, FERNANDO; CARNIEL, BEATRIZ F.; HOLLOWAY, MARK; MITSI, ELENA; SMITH, EMMA; GRITZFELD, JENNA F.; SOLORZANO, CARLA; REINE, JESUS; POJAR, SHERIN; et al. Inflammation induced by influenza virus impairs human innate immune control of pneumococcus. NATURE IMMUNOLOGY, v. 19, n. 12, p. 1299+, . (12/19278-6, 13/08216-2)
ZUCOLOTO, AMANDA Z.; MANCHOPE, MARILIA F.; STAURENGO-FERRARI, LARRISA; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; ANTUNES, MAISA M.; MENEZES, GUSTAVO B.; CUNHA, FERNANDO Q.; CASAGRANDE, RUBIA; VERRI, JR., WALDICEU A.. Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-kappa B activation and cytokine production without antioxidant effects. Inflammation Research, v. 66, n. 7, p. 591-602, . (13/08216-2, 11/19670-0)
BASSI, GABRIEL SHIMIZU; MARTINS DIAS, DANIEL PENTEADO; FRANCHIN, MARCELO; TALBOT, JHIMMY; REIS, DANIEL GUSTAVO; MENEZES, GUSTAVO BATISTA; CASTANIA, JACI AIRTON; GARCIA-CAIRASCO, NORBERTO; MORAES RESSTEL, LEONARDO BARBOSA; SALGADO, HELIO CESAR; et al. Modulation of experimental arthritis by vagal sensory and central brain stimulation. BRAIN BEHAVIOR AND IMMUNITY, v. 64, p. 330-343, . (15/20463-0, 13/20549-7, 13/08216-2, 11/20343-4, 12/04237-2)
FRANCO, LUIS H.; FLEURI, ANNA K. A.; PELLISON, NATALIA C.; QUIRINO, GUSTAVO F. S.; HORTA, CATARINA V.; DE CARVALHO, RENAN V. H.; OLIVEIRA, SERGIO C.; ZAMBONI, DARIO S.. Autophagy downstream of endosomal Toll-like receptor signaling in macrophages is a key mechanism for resistance to Leishmania major infection. Journal of Biological Chemistry, v. 292, n. 32, p. 13087-13096, . (13/08216-2, 14/04684-4)
ANDRADE, WARRISON A.; ZAMBONI, DARIO S.. Inflammasome-dependent Mechanisms Involved in Sensing and Restriction of Bacterial Replication. CURRENT ISSUES IN MOLECULAR BIOLOGY, v. 25, p. 99-131, . (14/50268-2, 13/08216-2, 14/04684-4)
LOPES, ALEXANDRE H.; BRANDOLINI, LAURA; ARAMINI, ANDREA; BIANCHINI, GIANLUCA; SILVA, RANGEL L.; ZAPERLON, ANA C.; VERRI, JR., WALDICEU A.; ALVES-FILHO, JOSE C.; CUNHA, FERNANDO Q.; TEIXEIRA, MAURO M.; et al. DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain. PHARMACOLOGICAL RESEARCH, v. 103, p. 69-79, . (13/08216-2, 11/19670-0)
TOSTES, RITA C.; CARNEIRO, FERNANDO S.; CARVALHO, MARIA HELENA C.; RECKELHOFF, JANE F.. Reactive oxygen species: players in the cardiovascular effects of testosterone. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, v. 310, n. 1, p. R1-R14, . (13/08216-2)
SACRAMENTO, LAIS; TREVELIN, SILVIA C.; NASCIMENTO, MANUELA S.; LIMA-JUNIOR, DJALMA S.; COSTA, DIEGO L.; ALMEIDA, ROQUE P.; CUNHA, FERNANDO Q.; SILVA, JOAO S.; CARREGARO, VANESSA. Toll-Like Receptor 9 Signaling in Dendritic Cells Regulates Neutrophil Recruitment to Inflammatory Foci following Leishmania infantum Infection. Infection and Immunity, v. 83, n. 12, p. 4604-4616, . (13/08216-2, 12/14524-9)
FORNARI, THAIS A.; DONATE, PAULA B.; ASSIS, AMANDA F.; MACEDO, CLAUDIA; SAKAMOTO-HOJO, ELZA T.; DONADI, EDUARDO A.; PASSOS, GERALDO A.. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice. PLoS One, v. 10, n. 11, . (13/08216-2, 08/56594-8)
SILVA, RANGEL L.; LOPES, ALEXANDRE H.; FRANCA, RAFAEL O.; VIEIRA, SILVIO M.; SILVA, ELLEN C. C.; AMORIM, RODRIGO C. N.; CUNHA, FERNANDO Q.; POHLIT, ADRIAN M.; CUNHA, THIAGO M.. The Quassinoid Isobrucein B Reduces Inflammatory Hyperalgesia and Cytokine Production by Post-transcriptional Modulation. Journal of Natural Products, v. 78, n. 2, p. 241-249, . (13/08216-2)
DE ALMEIDA, LETICIA; DA SILVA, ALEXANDRE L. N.; RODRIGUES, TAMARA S.; OLIVEIRA, SAMUEL; ISHIMOTO, ADRIENE Y.; SERIBELLI, AMANDA A.; BECERRA, AMANDA; ANDRADE, WARRISON A.; ATAIDE, MARCO A.; CAETANO, CAMILA C. S.; et al. Identification of immunomodulatory drugs that inhibit multiple inflammasomes and impair SARS-CoV-2 infection. SCIENCE ADVANCES, v. 8, n. 37, p. 15-pg., . (20/04964-8, 13/08216-2, 19/11342-6)
WANDERLEY, CARLOS WAGNER S.; MAGANIN, ALEXANDRE G. M.; ADJAFRE, BEATRIZ; MENDES, ATLANTE S.; SILVA, CONCEICAO ELIDIANNE ANIBAL; QUADROS, ANDREZA URBA; LUIZ, JOAO PAULO MESQUITA; SILVA, CAMILA MEIRELLES S.; SILVA, NICOLE R.; OLIVEIRA, FRANCISCO FABIO BEZERRA; et al. PD-1/PD-L1 Inhibition Enhances Chemotherapy-Induced Neuropathic Pain by Suppressing Neuroimmune Antinociceptive Signaling. CANCER IMMUNOLOGY RESEARCH, v. 10, n. 11, p. 10-pg., . (13/08216-2, 17/25308-9)
SANTOS, JEIMISON D.; OLIVEIRA-NETO, JOSE T.; BARROS, PAULA R.; DAMASCENO, LUIS E. A.; LAUTHERBACH, NATALIA; ASSIS, ANA P.; SILVA, CARLOS A. A.; SORGI, CARLOS A.; FACCIOLI, LUCIA H.; KETTELHUT, ISIS C.; et al. Th17 cell-linked mechanisms mediate vascular dysfunction induced by testosterone in a mouse model of gender-affirming hormone therapy. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 323, n. 2, p. 14-pg., . (13/08216-2)
THAÍSE OLIVEIRA QUARESMA; SÉRGIO COUTO LUNA DE ALMEIDA; TARCÍLIA APARECIDA DA SILVA; PAULO LOUZADA JÚNIOR; RENÊ DONIZETI RIBEIRO DE OLIVEIRA. Comparative study of the synovial levels of RANKL and OPG in rheumatoid arthritis, spondyloarthritis and osteoarthritis. ADVANCES IN RHEUMATOLOGY, v. 63, . (13/08216-2)
CORSI-ZUELLI, FABIANA; MARQUES, LEONARDO; DA ROZA, DAIANE LEITE; LOUREIRO, CAMILA MARCELINO; SHUHAMA, ROSANA; DI FORTI, MARTA; MENEZES, PAULO ROSSI; LOUZADA-JUNIOR, PAULO; DEL-BEN, CRISTINA MARTA. The independent and combined effects of cannabis use and systemic inflammation during the early stages of psychosis: exploring the two-hit hypothesis. PSYCHOLOGICAL MEDICINE, v. N/A, p. 11-pg., . (12/05178-0, 17/13353-0, 13/11167-3, 13/08216-2, 19/13229-2, 18/07581-2)
DE CARVALHO, RENA N. V. H.; SILVA, ALEXANDRE L. N.; SANTOS, LEONARDO L.; ANDRADE, WARRISON A.; DE SA, KEYLA S. G.; ZANNBONI, DARIO S.. Macrophage priming is dispensable for NLRP3 inflammasome activation and restriction of Leishmania amazonensis replication. Journal of Leukocyte Biology, v. 106, n. 3, p. 10-pg., . (13/08216-2, 14/04684-4)
BASSI, GABRIEL SHIMIZU; ULLOA, LUIS; SANTOS, VICTOR RODRIGUES; DEL VECCHIO, FLAVIO; DELFINO-PEREIRA, POLIANNA; RODRIGUES, GERSON JHONATAN; CASTANIA, JACI AIRTON; CUNHA, FERNANDO DE QUEIROZ; SALGADO, HELIO CESAR; CUNHA, THIAGO MATTAR; et al. Cortical stimulation in conscious rats controls joint inflammation. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 84, p. 13-pg., . (13/20549-7, 13/08216-2, 12/04237-2, 11/20343-4)
SISTI, FLAVIA; WANG, SOUJUAN; BRANDT, STEPHANIE L.; GLOSSON-BYERS, NICOLE; MAYO, LINDSEY D.; SON, YOUNG MIN; STURGEON, SARAH; FILGUEIRAS, LUCIANO; JANCAR, SONIA; WONG, HECTOR; et al. Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis. SCIENCE SIGNALING, v. 11, n. 528, p. 14-pg., . (13/08216-2, 11/19670-0)
PERNOMIAN, LARISSA; MOREIRA, JOSIMAR DORNELAS; GOMES, MAYARA SANTOS. In the View of Endothelial Microparticles: Novel Perspectives for Diagnostic and Pharmacological Management of Cardiovascular Risk during Diabetes Distress. JOURNAL OF DIABETES RESEARCH, v. 2018, p. 7-pg., . (12/00640-7, 14/17740-0, 13/08216-2, 12/09019-3, 09/01005-0)
PERNOMIAN, LARISSA; GIMENES, LILIAN R.; GOMES, MAYARA S.; DO VALE, BRUNO N.; CARDOSO, CRISTINA R. B.; DE OLIVEIRA, ANA M.; MOREIRA, JOSIMAR D.. Endothelinergic Contractile Hyperreactivity in Rat Contralateral Carotid to Balloon Injury: Integrated Role for ETB Receptors and Superoxide Anion. BIOMED RESEARCH INTERNATIONAL, v. 2017, p. 13-pg., . (12/00640-7, 14/17740-0, 13/08216-2, 12/09019-3, 09/01005-0)
MORICONI, ALESSIO; CUNHA, THIAGO M.; SOUZA, GUILHERME R.; LOPES, ALEXANDRE H.; CUNHA, FERNANDO Q.; CARNEIRO, VICTOR L.; PINTO, LARISSA G.; BRANDOLINI, LAURA; ARAMINI, ANDREA; BIZZARRI, CINZIA; et al. Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 111, n. 47, p. 6-pg., . (13/08216-2, 11/19670-0)
LOURENCO-GONZALEZ, YURI; FATTORI, VICTOR; DOMICIANO, TALITA P.; ROSSANEIS, ANA C.; BORGHI, SERGIO M.; ZANINELLI, TIAGO H.; BERNARDY, CATIA C. F.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; et al. Repurposing of the Nootropic Drug Vinpocetine as an Analgesic and Anti-Inflammatory Agent: Evidence in a Mouse Model of Superoxide Anion-Triggered Inflammation. Mediators of Inflammation, v. 2019, p. 14-pg., . (13/08216-2, 11/19670-0)
DE MELO, BRUNO MARCEL SILVA; VERAS, FLAVIO PROTASIO; ZWICKY, PASCALE; LIMA, DIOGENES; INGELFINGER, FLORIAN; MARTINS, TIMNA VARELA; PRADO, DOUGLAS DA SILVA; SCHARLI, STEFANIE; PUBLIO, GABRIEL; HIROKI, CARLOS HIROJI; et al. S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/ Type 3 Immunity. JOURNAL OF INVESTIGATIVE DERMATOLOGY, v. 143, n. 9, p. 19-pg., . (13/08216-2, 20/13349-5, 18/19312-6)
GERMANO, THAIS ANDRADE; RAMOS DE OLIVEIRA, MATHEUS FINGER; AZIZ, SHAHID; ROCHA OLIVEIRA, ANTONIO EDSON; DA CRUZ SARAIVA, KATIA DANIELLA; DOS SANTOS, CLESIVAN PEREIRA; HERBSTER MOURA, CARLOS FARLEY; COSTA, JOSE HELIO. Transcriptome profiling of cashew apples (Anacardium occidentale) genotypes reveals specific genes linked to firmness and color during pseudofruit development. Plant Molecular Biology, v. 109, n. 1-2, p. 18-pg., . (13/08216-2, 19/22579-7)
LUSCHER-DIAS, THOMAZ; CONCEICAO, IZABELA MAMEDE; SCHUCH, VIVIANE; MARACAJA-COUTINHO, VINICIUS; AMARAL, PAULO P.; NAKAYA, HELDER I.; HON, CC. Long non-coding RNAs associated with infection and vaccine-induced immunity. NON-CODING GENOME, v. 65, n. 4, p. 13-pg., . (18/14933-2, 13/08216-2, 20/04836-0, 17/27131-9, 18/21934-5)
RODRIGUES, TAMARA S.; DE SA, KEYLA S. G.; ISHIMOTO, ADRIENE Y.; BECERRA, AMANDA; OLIVEIRA, SAMUEL; ALMEIDA, LETICIA; GONCALVES, V, AUGUSTO; PERUCELLO, DEBORA B.; ANDRADE, WARRISON A.; CASTRO, RICARDO; et al. Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients. JOURNAL OF EXPERIMENTAL MEDICINE, v. 218, n. 3, . (20/04964-8, 13/08216-2, 19/11342-6)
DE MATOS, NATALIA ALVES; LIMA, ONESIA CRISTINA OLIVEIRA; DA SILVA, JOSIANE FERNANDES; PINEROS, ANNIE ROCIO; TAVARES, JULIANA CARVALHO; LEMOS, VIRGINIA SOARES; ALVES-FILHO, JOSE CARLOS; KLEIN, ANDRE. Blockade of protease-activated receptor 2 attenuates allergen-mediated acute lung inflammation and leukocyte recruitment in mice. JOURNAL OF BIOSCIENCES, v. 47, n. 1, . (13/08216-2)
YANG, NICOLE J.; ISENSEE, JOERG; NEEL, V, DYLAN; QUADROS, ANDREZA U.; ZHANG, HAN-XIONG BEAR; LAUZADIS, JUSTAS; LIU, SAI MAN; SHIERS, STEPHANIE; BELU, ANDREEA; PALAN, SHILPA; et al. Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2(+) DRG sensory neurons. NATURE NEUROSCIENCE, . (13/08216-2)
GUIMARAESI, RAFAELA M.; DAVOLI-FERREIRA, MARCELA; FONSECA, MIRIAM M.; DAMASCENO, LUIS EDUARDO A.; SANTA-CECILIA, V, FLAVIA; KUSUDA, RICARDO; MENEZES, GUSTAVO B.; CUNHA, FERNANDO Q.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.. Frontline Science: Blood-circulating leukocytes fail to infiltrate the spinal cord parenchyma after spared nerve injury. Journal of Leukocyte Biology, v. 106, n. 3, SI, p. 541-551, . (13/08216-2, 11/19670-0)
COSTA, EDUARDO D.; SILVA, JOSIANE F.; GARCIA, DANIELA C.; WAINSTEIN, ALBERTO J.; REZENDE, BRUNO A.; TOSTES, RITA C.; TEIXEIRA, MAURO M.; CORTES, STEYNER F.; LEMOS, VIRGINIA S.. Decreased expression of neuronal nitric oxide synthase contributes to the endothelial dysfunction associated with cigarette smoking in human. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, v. 98, p. 20-28, . (13/08216-2, 16/16207-1)
DE LIMA, DIOGENES S.; CARDOZO, LUCAS E.; MARACAJA-COUTINHO, VINICIUS; SUHRBIER, ANDREAS; MANE, KARIM; JEFFRIES, DAVID; SILVEIRA, EDUARDO L. V.; AMARAL, PAULO P.; RAPPUOLI, RINO; DE SILVA, THUSHAN I.; et al. Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 116, n. 34, p. 17121-17126, . (12/19278-6, 13/08216-2, 17/50137-3)
FERREIRA, NATHANNE SANTOS; BRUDER-NASCIMENTO, THIAGO; PEREIRA, CAMILA ANDRE; ZANOTTO, CAMILA ZILLIOTO; PRADO, DOUGLAS SILVA; SILVA, JOSIANE FERNANDES; RASSI, DIANE MEYRE; FOSS-FREITAS, MARIA CRISTINA; ALVES-FILHO, JOSE CARLOS; CARLOS, DANIELA; et al. NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus. CELLS, v. 8, n. 12, . (13/08216-2)
CASTANHEIRA, FERNANDA VARGAS E SILVA; DE LIMA, KALIL ALVES; MARTELOSSI CEBINELLI, GUILHERME CESAR; SONEGO, FABIANE; KANASHIRO, ALEXANDRE; COLON, DAVID-FERNANDO; BORGES, VANESSA; CZAIKOSKI, PAULA GISELLE; MOTA, JOSE MAURICIO; CUNHA, THIAGO MATTAR; et al. CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis. Shock, v. 52, n. 5, p. E100-E106, . (13/08216-2, 12/04132-6)
ZHANG, BING; MA, SAI; RACHMIN, INBAL; HE, MEGAN; BARAL, PANKAJ; CHOI, SEKYU; GONCALVES, WILLIAM A.; SHWARTZ, YULIA; FAST, EVA M.; SU, YIQUN; et al. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature, . (13/08216-2)
PEREIRA, CAMILA A.; CARLOS, DANIELA; FERREIRA, NATHANNE S.; SILVA, JOSIANE F.; ZANOTTO, CAMILA Z.; ZAMBONI, DARIO S.; GARCIA, VALERIA D.; VENTURA, DORA FIX; SILVA, JOAO S.; TOSTES, RITA C.. Mitochondrial DNA Promotes NLRP3 Inflammasome Activation and Contributes to Endothelial Dysfunction and Inflammation in Type 1 Diabetes. FRONTIERS IN PHYSIOLOGY, v. 10, . (13/08216-2, 16/17303-4)
GUPTA, GAURAV; SANTANA, ALYNNE K. M.; GOMES, CIRO M.; TURATTI, ALINE; MILANEZI, CRISTIANE M.; BUENO FILHO, ROBERTO; FUZO, CARLOS; ALMEIDA, ROQUE P.; CARREGARO, VANESSA; ROSELINO, ANA M.; et al. Inflammasome gene expression is associated with immunopathology in human localized cutaneous leishmaniasis. Cellular Immunology, v. 341, . (13/08216-2)
BATISTA, V, NATHALIA; BARBAGALLO, MARIALUISA; OLIVEIRA, VIVIAN L. S.; CASTRO-GOMES, THIAGO; OLIVEIRA, RENE D. R.; LOUZADA-JUNIOR, PAULO; PINHEIRO, GERALDO R. C.; MANTOVANI, ALBERTO; TEIXEIRA, MAURO M.; GARLANDA, CECILIA; et al. The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals. JOURNAL OF IMMUNOLOGY, v. 202, n. 6, p. 1807-1814, . (13/08216-2)
CARDOZO, LUCAS E.; RUSSO, PEDRO S. T.; GOMES-CORREIA, BRUNO; ARAUJO-PEREIRA, MARIANA; SEPULVEDA-HERMOSILLA, GONZALO; MARACAJA-COUTINHO, VINICIUS; NAKAYA, I, HELDER. webCEMiTool: Co-expression Modular Analysis Made Easy. FRONTIERS IN GENETICS, v. 10, . (13/08216-2, 17/05762-7, 18/10748-6, 12/19278-6)
TAIRA, T. M.; LIMA, V; PRADO, D. S.; SILVA, T. A.; ISSA, J. P. M.; DA SILVA, L. A. B.; ZAMBONI, D. S.; CUNHA, F. Q.; FUKADA, S. Y.. NLRP12 Attenuates Inflammatory Bone Loss in Experimental Apical Periodontitis. JOURNAL OF DENTAL RESEARCH, v. 98, n. 4, p. 476-484, . (13/08216-2, 15/09034-0)
PEREZ, MALENA M.; MARTINS, LARISSA M. S.; DIAS, MURILO S.; PEREIRA, CAMILA A.; LEITE, JEFFERSON A.; GONCALVES, ENRICO C. S.; DE ALMEIDA, PAULA Z.; DE FREITAS, EMANUELLE N.; TOSTES, RITA C.; RAMOS, SIMONE G.; et al. Interleukin-17/interleukin-17 receptor axis elicits intestinal neutrophil migration, restrains gut dysbiosis and lipopolysaccharide translocation in high-fat diet-induced metabolic syndrome model. IMMUNOLOGY, v. 156, n. 4, p. 339-355, . (12/10395-0, 13/08216-2, 14/21020-2)
BORGHI, SERGIO M.; FATTORI, VICTOR; RUIZ-MIYAZAWA, KENJI W.; BERTOZZI, MARIANA M.; LOURENCO-GONZALEZ, YURI; TATAKIHARA, ROBERTO I.; BUSSMANN, ALLAN J. C.; MAZZUCO, TANIA L.; CASAGRANDE, RUBIA; VERRI, JR., WALDICEU A.. Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF-kappa B activity. Life Sciences, v. 208, p. 221-231, . (13/08216-2)
PERNOMIAN, LARISSA; GOMES, MAYARA S.; TOMICH DE PAULA DA SILVA, CARLOS H.; ROSA, JOAQUIN M. C.. Reverse Induced Fit-Driven MAS-Downstream Transduction: Looking for Metabotropic Agonists. Current Medicinal Chemistry, v. 24, n. 39, p. 4360-4367, . (12/00640-7, 13/08216-2, 14/17740-0, 12/09019-3)
SESTI-COSTA, RENATA; SANTIAGO FRANCOZO, MARCELA CRISTINA; SILVA, GRACE KELLY; PROENCA-MODENA, JOSE LUIZ; SILVA, JOAO SANTANA. TLR3 is required for survival following Coxsackievirus B3 infection by driving T lymphocyte activation and polarization: The role of dendritic cells. PLoS One, v. 12, n. 10, . (13/08216-2, 12/20786-6)
NASCIMENTO, DANIELE C.; MELO, PAULO H.; PINEROS, ANNIE R.; FERREIRA, RAPHAEL G.; COLON, DAVID F.; DONATE, PAULA B.; CASTANHEIRA, FERNANDA V.; GOZZI, ALINE; CZAIKOSKI, PAULA G.; NIEDBALA, WANDA; et al. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. NATURE COMMUNICATIONS, v. 8, . (13/08216-2, 11/19670-0)
KANASHIRO, ALEXANDRE; SONEGO, FABIANE; FERREIRA, RAPHAEL G.; CASTANHEIRA, FERNANDA V. S.; LEITE, CAIO A.; BORGES, VANESSA F.; NASCIMENTO, DANIELE C.; COLON, DAVID F.; ALVES-FILHO, JOSE CARLOS; ULLOA, LUIS; et al. Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis. PHARMACOLOGICAL RESEARCH, v. 117, p. 1-8, . (13/08216-2, 12/04237-2, 11/19670-0, 11/20343-4)
MASSIS, LILIANA M.; ASSIS-MARQUES, MARIANA A.; CASTANHEIRA, FERNANDA V. S.; CAPOBIANCO, YASMIN J.; BALESTRA, ANDIAMIRA C.; ESCOLL, PEDRO; WOOD, REBECCA E.; MANIN, GRAZIELE Z.; CORREA, VANI M. A.; ALVES-FILHO, JOSE C.; et al. Legionella longbeachae Is Immunologically Silent and Highly Virulent In Vivo. Journal of Infectious Diseases, v. 215, n. 3, p. 440-451, . (13/08216-2, 14/04684-4, 10/20600-4, 14/50268-2, 12/09363-6)
FATTORI, VICTOR; SERAFIM, KARLA G. G.; ZARPELON, ANA C.; BORGHI, SERGIO M.; PINHO-RIBEIRO, FELIPE A.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; CASAGRANDE, RUBIA; VERRI, JR., WALDICEU A.. Differential regulation of oxidative stress and cytokine production by endothelin ETA and ETB receptors in superoxide anion-induced inflammation and pain in mice. Journal of Drug Targeting, v. 25, n. 3, p. 264-274, . (13/08216-2, 11/19670-0)
PEREIRA, CAMILA A.; RODRIGUES, FERNANDA L.; RUGINSK, SILVIA G.; ZANOTTO, CAMILA Z.; RODRIGUES, JOSE A.; DUARTE, DIEGO A.; COSTA-NETO, CLAUDIO M.; RESSTEL, LEONARDO B.; CARNEIRO, FERNANDO S.; TOSTES, RITA C.. Chronic treatment with fluoxetine modulates vascular adrenergic responses by inhibition of pre- and post-synaptic mechanisms. European Journal of Pharmacology, v. 800, p. 70-80, . (13/08216-2)
FONSECA, MIRIAM D.; CUNHA, FERNANDO Q.; KASHFI, KHOSROW; CUNHA, THIAGO M.. NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain. PHARMACOLOGY RESEARCH & PERSPECTIVES, v. 3, n. 3, . (13/08216-2, 11/19670-0)
SOUZA-SILVA, LEONARDO; ALVES-LOPES, RHEURE; MIGUEZ, JESSICA SILVA; DELA JUSTINA, VANESSA; NEVES, KARLA BIANCA; MESTRINER, FABIOLA LESLIE; TOSTES, RITA DE CASSIA; GIACHINI, FERNANDA REGINA; LIMA, VICTOR VITORINO. Glycosylation with O-linked beta-N-acetylglucosamine induces vascular dysfunction via production of superoxide anion/reactive oxygen species. Canadian Journal of Physiology and Pharmacology, v. 96, n. 3, . (13/08216-2)
DA COSTA, RAFAEL M.; DA SILVA, JOSIANE F.; ALVES, JULIANO V.; DIAS, THIAGO B.; RASSI, DIANE M.; GARCIA, LUIS V.; LOBATO, NUBIA DE SOUZA; TOSTES, RITA C.. Increased O-GlcNAcylation of Endothelial Nitric Oxide Synthase Compromises the Anti-contractile Properties of Perivascular Adipose Tissue in Metabolic Syndrome. FRONTIERS IN PHYSIOLOGY, v. 9, . (13/08216-2)
PINTO, LARISSA G.; SOUZA, GUILHERME R.; KUSUDA, RICARDO; LOPES, ALEXANDRE H.; SANT'ANNA, MORENA B.; CUNHA, FERNANDO Q.; FERREIRA, SERGIO H.; CUNHA, THIAGO M.. Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice. Molecular Neurobiology, v. 56, n. 8, p. 5715-5728, . (13/08216-2, 10/04043-8, 11/19670-0)
LIMA, VILMA; MELO, IRACEMA MATOS; TAIRA, THAISE MAYUMI; WILCHES BUITRAGO, LISETH YAMILE; RORIZ FONTELES, CRISTIANE SA; ALMEIDA MOREIRA LEAL, LUZIA KALYNE; DE QUEIROZ SOUZA, ANA SHEILA; ALMEIDA, TALYSSON SILVA; DA COSTA FILHO, RAIMUNDO NOGUEIRA; MORAES, MANOEL ODORICO; et al. Uncaria tomentosa reduces osteoclastic bone loss in vivo. Phytomedicine, v. 79, . (15/09034-0, 13/08216-2)
RUIZ-MIYAZAWA, KENJI W.; STAURENGO-FERRARI, LARISSA; PINHO-RIBEIRO, FELIPE A.; FATTORI, VICTOR; ZANINELLI, TIAGO H.; BADARO-GARCIA, STEPHANIE; BORGHI, SERGIO M.; ANDRADE, KETLEM C.; CLEMENTE-NAPIMOGA, JULIANA T.; ALVES-FILHO, JOSE C.; et al. 15d-PGJ(2)-loaded nanocapsules ameliorate experimental gout arthritis by reducing pain and inflammation in a PPAR-gamma-sensitive manner in mice. SCIENTIFIC REPORTS, v. 8, . (13/08216-2, 10/15014-9, 11/19670-0)
STAURENGO-FERRARI, LARISSA; RUIZ-MIYAZAWA, KENJI W.; PINHO-RIBEIRO, FELIPE A.; FATTORI, VICTOR; ZANINELLI, TIAGO H.; BADARO-GARCIA, STEPHANIE; BORGHI, SERGIO M.; CARVALHO, THACYANA T.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; et al. Trans-Chalcone Attenuates Pain and Inflammation in Experimental Acute Gout Arthritis in Mice. FRONTIERS IN PHARMACOLOGY, v. 9, . (13/08216-2, 11/19670-0)
FATTORI, VICTOR; ZARPELON, ANA C.; STAURENGO-FERRARI, LARISSA; BORGHI, SERGIO M.; ZANINELII, TIAGO H.; DA COSTA, FERNANDO B.; AIVES, JOSE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; CASAGRANDE, RUBIA; et al. Budlein A, a Sesquiterpene Lactone From Viguiera robusta, Alleviates Pain and Inflammation in a Model o Acute Gout Arthritis in Mice. FRONTIERS IN PHARMACOLOGY, v. 9, . (13/08216-2, 11/19670-0)
RUIZ-MIYAZAWA, KENJI W.; BORGHI, SERGIO M.; PINHO-RIBEIRO, FELIPE A.; STAURENGO-FERRARI, LARISSA; FATTORI, VICTOR; FERNANDES, GLAURA S. A.; CASELLA, ANTONIO M.; ALVES-FILHO, JOSE C.; CUNHA, THIAGO M.; CUNHA, FERNANDO Q.; et al. The citrus flavanone naringenin reduces gout-induced joint pain and inflammation in mice by inhibiting the activation of NF kappa B and macrophage release of IL-1 beta. Journal of Functional Foods, v. 48, p. 106-116, . (13/08216-2, 11/19670-0, 10/15014-9)
FERREIRA, RAPHAEL G.; RODRIGUES, LILIAN C.; NASCIMENTO, DANIELE C.; KANASHIRO, ALEXANDRE; MELO, PAULO H.; BORGES, VANESSA F.; GOZZI, ALINE; PRADO, DOUGLAS DA SILVA; BORGES, MARCOS C.; RAMALHO, FERNANDO S.; et al. Galectin-3 aggravates experimental polymicrobial sepsis by impairing neutrophil recruitment to the infectious focus. Journal of Infection, v. 77, n. 5, p. 391-397, . (13/08216-2, 11/19670-0)
WILCHES-BUITRAGO, L.; VIACAVA, P. R.; CUNHA, F. Q.; ALVES-FILHO, J. C.; FUKADA, S. Y.. Fructose 1,6-bisphosphate inhibits osteoclastogenesis by attenuating RANKL-induced NF-kappa B/NFATc-1. Inflammation Research, v. 68, n. 5, p. 415-421, . (15/09034-0, 13/08216-2)
ZHANG, BING; MA, SAI; RACHMIN, INBAL; HE, MEGAN; BARAL, PANKAJ; CHOI, SEKYU; GONCALVES, WILLIAM A.; SHWARTZ, YULIA; FAST, EVA M.; SU, YIQUN; et al. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature, v. 577, n. 7792, p. 676+, . (13/08216-2)
VERAS, FLAVIO P.; PUBLIO, GABRIEL A.; MELO, BRUNO M.; PRADO, DOUGLAS S.; NORBIATO, THAINA; CECILIO, NERRY T.; HIROKI, CARLOS; DAMASCENO, LUIS EDUARDO A.; JUNG, REBECCA; TOLLER-KAWAHISA, JULIANA E.; et al. Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation. CELL REPORTS, v. 41, n. 13, p. 23-pg., . (13/08216-2, 16/10867-0)
BORGHI, SERGIO M.; ZANINELLI, TIAGO H.; SARAIVA-SANTOS, TELMA; BERTOZZI, MARIANA M.; CARDOSO, RENATO D. R.; CARVALHO, THACYANA T.; FERRAZ, CAMILA R.; CAMILIOS-NETO, DOUMIT; CUNHA, FERNANDO Q.; CUNHA, THIAGO M.; et al. Brief research report: Repurposing pentoxifylline to treat intense acute swimming-Induced delayed-onset muscle soreness in mice: Targeting peripheral and spinal cord nociceptive mechanisms. FRONTIERS IN PHARMACOLOGY, v. 13, p. 9-pg., . (13/08216-2)
SANTOS, VIVIANE CORREA; OLIVEIRA, ANTONIO EDSON ROCHA; CAMPOS, AUGUSTO CESAR BROILO; REIS-CUNHA, JOAO LUIS; BARTHOLOMEU, DANIELLA CASTANHEIRA; TEIXEIRA, SANTUZA MARIA RIBEIRO; LIMA, ANA PAULA C. A.; FERREIRA, RAFAELA SALGADO. The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites. SCIENTIFIC REPORTS, v. 11, n. 1, . (13/08216-2, 19/22579-7)
NASCIMENTO, DANIELE CARVALHO; VIACAVA, PAULA RAMOS; FERREIRA, RAPHAEL GOMES; DAMACENO, MARINA ALVES; PINEROS, ANNIE ROCIO; MELO, PAULO HENRIQUE; DONATE, PAULA BARBIM; TOLLER-KAWAHISA, JULIANA ESCHER; ZOPPI, DANIEL; VERAS, FLAVIO PROTASIO; et al. Sepsis expands a CD39(+) plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity. IMMUNITY, v. 54, n. 9, p. 2024+, . (13/08216-2, 15/25974-3, 12/10100-0, 15/25364-0)
SOUZA, CAMILA O. S.; KETELUT-CARNEIRO, NATALIA; MILANEZI, CRISTIANE M.; FACCIOLI, LUCIA H.; GARDINASSI, LUIZ G.; SILVA, JOAO S.. NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8(+) T cell responses. ISCIENCE, v. 24, n. 6, . (13/08216-2, 12/14524-9, 13/21295-9, 15/21605-3)
ZANATA, GRAZIELE C.; PINTO, LARISSA G.; DA SILVA, NICOLE R.; LOPES, ALEXANDRE H. P.; DE OLIVEIRA, FRANCISCO F. B.; SCHIVO, IEDA R. S.; CUNHA, FERNANDO Q.; MCNAUGHTON, PETER; CUNHA, THIAGO M.; SILVA, RANGEL L.. Blockade of bradykinin receptors or angiotensin II type 2 receptor prevents paclitaxel-associated acute pain syndrome in mice. EUROPEAN JOURNAL OF PAIN, v. 25, n. 1, p. 189-198, . (13/08216-2, 17/50419-9)
CREIGHTON, RACHEL; SCHUCH, VIVIANE; URBANSKI, ALYSSON H.; GIDDALURU, JEEVAN; COSTA-MARTINS, ANDRE G.; NAKAYA, I, HELDER. Network vaccinology. SEMINARS IN IMMUNOLOGY, v. 50, . (18/14933-2, 17/27131-9, 13/08216-2, 18/21934-5)
VERAS, FLAVIO PROTASIO; PONTELLI, MARJORIE CORNEJO; SILVA, CAMILA MEIRELLES; TOLLER-KAWAHISA, JULIANA E.; DE LIMA, MIKHAEL; NASCIMENTO, DANIELE CARVALHO; SCHNEIDER, AYDA HENRIQUES; CAETITE, DIEGO; TAVARES, LUCAS ALVES; PAIVA, ISADORA M.; et al. SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology. JOURNAL OF EXPERIMENTAL MEDICINE, v. 217, n. 12, . (13/08216-2, 20/05601-6)
DE CARVALHO, RENAN V. H.; ZAMBONI, DARIO S.. Inflammasome Activation in Response to Intracellular Protozoan Parasites. Trends in Parasitology, v. 36, n. 5, p. 459-472, . (13/08216-2, 18/14398-0, 14/04684-4)
KETELUT-CARNEIRO, NATALIA; SILVA SOUZA, CAMILA OLIVEIRA; BENEVIDES, LUCIANA; GARDINASSI, LUIZ GUSTAVO; SILVA, MARIA CLAUDIA; TAVARES, LUCAS ALVES; ZAMBONI, DARIO SIMOES; SILVA, JOAO SANTANA. Caspase-11-dependent IL-1 alpha release boosts Th17 immunity against Paracoccidioides brasiliensis. PLOS PATHOGENS, v. 15, n. 8, . (13/08216-2, 13/21295-9, 12/14524-9)
DE CASTRO-JORGE, LUIZA A.; DE CARVALHO, RENAN V. H.; KLEIN, TALINE M.; HIROKI, CARLOS H.; LOPES, ALEXANDRE H.; GUIMARAES, RAFAELA M.; FUMAGALLI, MARCILIO JORGE; FLORIANO, VITOR G.; AGOSTINHO, MAYARA R.; SLHESSARENKO, RENATA DEZENGRINI; et al. The NLRP3 inflammasome is involved with the pathogenesis of Mayaro virus. PLOS PATHOGENS, v. 15, n. 9, . (13/08216-2, 14/04684-4)
FRANCOZO, MARCELA C. S.; COSTA, FREDERICO R. C.; GUERRA-GOMES, ISABEL C.; SILVA, JOAO S.; SESTI-COSTA, RENATA. Dendritic cells and regulatory T cells expressing CCR4 provide resistance to coxsackievirus B5-induced pancreatitis. SCIENTIFIC REPORTS, v. 9, . (13/08216-2, 11/15832-6)
HELUANY, CINTIA SCUCUGLIA; SCHARF, PABLO; SCHNEIDER, AYDA HENRIQUES; DONATE, PAULA BARBIM; PEDREIRA FILHO, WALTER DOS REIS; DE OLIVEIRA, TIAGO FRANCO; CUNHA, FERNANDO QUEIROZ; POLISELLI FARSKY, SANDRA HELENA. oxic mechanisms of cigarette smoke and heat-not-burn tobacco vapor inhalation on rheumatoid arthriti. Science of The Total Environment, v. 809, . (19/19573-7, 13/08216-2, 17/26998-9)
LEITE, JEFFERSON ANTONIO; PESSENDA, GABRIELA; GUERRA-GOMES, ISABEL C.; MENDONCA DE SANTANA, ALYNNE KAREN; PEREIRA, CAMILA ANDRE; CAMPOS COSTA, FREDERICO RIBEIRO; RAMOS, SIMONE G.; ZAMBONI, DARIO SIMOES; CAETANO FARIA, ANA MARIA; DE ALMEIDA, DANILO CANDIDO; et al. The DNA Sensor AIM2 Protects against Streptozotocin-Induced Type 1 Diabetes by Regulating Intestinal Homeostasis via the IL-18 Pathway. CELLS, v. 9, n. 4, . (12/10395-0, 16/25116-0, 13/08216-2)
SOUTO, FABRICIO O.; CASTANHEIRA, FERNANDA V. S.; TREVELIN, SILVIA C.; LIMA, BRAULIO H. F.; MARTELOSSI CEBINELLI, GUILHERME CESAR; TURATO, WALTER M.; AUXILIADORA-MARTINS, MARIA; BASILE-FILHO, ANIBAL; ALVES-FILHO, JOSE CARLOS; CUNHA, FERNANDO Q.. Liver X Receptor Activation Impairs Neutrophil Functions and Aggravates Sepsis. Journal of Infectious Diseases, v. 221, n. 9, p. 1542-1553, . (13/08216-2, 11/03293-3, 09/07651-1)
LEITE, CAIO ABNER; MOTA, JOSE MAURICIO; DE LIMA, KALIL ALVES; WANDERLEY, CARLOS WAGNER; NASCIMENTO, LETICIA ALMEIDA; FERREIRA, MARCELA DAVOLI; SOUZA SILVA, CAMILA MEIRELLES; COLON, DAVID FERNANDO; SAKITA, JULIANA YUMI; KANNEN, VINICIUS; et al. Paradoxical interaction between cancer and long-term postsepsis disorder: impairment of de novo carcinogenesis versus favoring the growth of established tumors. JOURNAL FOR IMMUNOTHERAPY OF CANCER, v. 8, n. 1, . (13/08216-2)
DA SILVA, JOSIANE FERNANDES; ALVES, V, JULIANO; SILVA-NETO, JULIO A.; COSTA, RAFAEL M.; NEVES, KARLA B.; ALVES-LOPES, RHEURE; CAMARGO, LIVIA L.; RIOS, FRANCISCO J.; MONTEZANO, AUGUSTO C.; TOUYZ, RHIAN M.; et al. Lysophosphatidylcholine induces oxidative stress in human endothelial cells via NOX5 activation - implications in atherosclerosis. Clinical Science, v. 135, n. 15, p. 1845-1858, . (13/08216-2, 17/26072-9)
DONATE, PAULA B.; DE LIMA, KALIL ALVES; PERES, RAPHAEL S.; ALMEIDA, FAUSTO; FUKADA, SANDRA Y.; SILVA, TARCILIA A.; NASCIMENTO, DANIELE C.; CECILIO, NERRY T.; TALBOT, JHIMMY; OLIVEIRA, RENE D.; et al. Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 118, n. 1, . (12/02438-0, 13/08216-2)
RODRIGUES, DANIEL; MACHADO, MIRELE R.; ALVES, JULIANO V.; FRAGA-SILVA, THAIS F. C.; MARTINS, RONALDO B.; CAMPOS, LIGIA C. B.; FRANCISCO, DANIELY F.; COUTO, ARIEL E. S.; BONATO, VANIA L. D.; ARRUDA, EURICO; et al. Cytokine storm in individuals with severe COVID-19 decreases endothelial cell antioxidant defense via downregulation of the Nrf2 transcriptional factor. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 325, n. 2, p. 12-pg., . (13/08216-2, 19/11213-1, 21/08847-9, 21/09273-6)
DA SILVA, JOSIANE FERNANDES; BOLSONI, JULIANA A.; DA COSTA, RAFAEL M.; ALVES, JULIANO, V; BRESSAN, ALECSANDER F. M.; SILVA, LUIZ EDUARDO, V; COSTA, TIAGO J.; OLIVEIRA, ANTONIO E. R.; MANZATO, CARLA P.; AGUIAR, CARLOS A.; et al. Aryl hydrocarbon receptor (AhR) activation contributes to high-fat diet-induced vascular dysfunction. British Journal of Pharmacology, v. 179, n. 12, p. 15-pg., . (18/21199-3, 13/08216-2, 19/22579-7, 16/16207-1)
MARUYAMA, SANDRA R.; DE SANTANA, ALYNNE K. M.; TAKAMIYA, NAYORE T.; TAKAHASHI, TALITA Y.; ROGERIO, LUANA A.; OLIVEIRA, CAIO A. B.; MILANEZI, CRISTIANE M.; TROMBELA, VIVIANE A.; CRUZ, ANGELA K.; JESUS, AMELIA R.; et al. Non-Leishmania Parasite in Fatal Visceral Leishmaniasis Like Disease, Brazil. Emerging Infectious Diseases, v. 25, n. 11, p. 2088-2092, . (18/05767-1, 18/26799-9, 13/08216-2, 16/20258-0, 17/16328-6, 19/03095-9)
GONCALVES, ANDRE N. A.; LEVER, MELISSA; RUSSO, PEDRO S. T.; GOMES-CORREIA, BRUNO; URBANSKI, ALYSSON H.; POLLARA, GABRIELE; NOURSADEGHI, MAHDAD; MARACAJA-COUTINHO, VINICIUS; NAKAYA, I, HELDER. Assessing the Impact of Sample Heterogeneity on Transcriptome Analysis of Human Diseases Using MDP Webtool. FRONTIERS IN GENETICS, v. 10, . (13/08216-2, 12/19278-6, 18/14933-2)
DE CARVALHO, RENAN V. H.; LIMA-JUNIOR, DJALMA S.; DA SILVA, MARCUS VINICIUS G.; DILUCCA, MARISA; RODRIGUES, TAMARA S.; HORTA, CATARINA V.; SILVA, ALEXANDRE L. N.; DA SILVA, PATRICK F.; FRANTZ, FABIANI G.; LORENZON, LUCAS B.; et al. Leishmania RNA virus exacerbates Leishmaniasis by subverting innate immunity via TLR3-mediated NLRP3 inflammasome inhibition. NATURE COMMUNICATIONS, v. 10, . (13/08216-2, 14/04684-4)
DAVOLI-FERREIRA, MARCELA; DE LIMA, KALIL A.; FONSECA, MIRIAM M.; GUIMARAES, RAFAELA M.; GOMES, I, FRANCISCO; CAVALLINI, MARIA C.; QUADROS, ANDREZA U.; KUSUDA, RICARDO; CUNHA, FERNANDO Q.; ALVES-FILHO, JOSE C.; et al. Regulatory T cells counteract neuropathic pain through inhibition of the Th1 response at the site of peripheral nerve injury. Pain, v. 161, n. 8, p. 1730-1743, . (13/08216-2, 11/19670-0)
ALVES, JULIANO VILELA; DA COSTA, RAFAEL MENEZES; PEREIRA, CAMILA ANDRE; FEDOCE, ALINE GARCIA; AGUIAR SILVA, CARLOS ALBERTO; CARNEIRO, FERNANDO SILVA; LOBATO, NUBIA SOUZA; TOSTES, RITA C.. Supraphysiological Levels of Testosterone Induce Vascular Dysfunction via Activation of the NLRP3 Inflammasome. FRONTIERS IN IMMUNOLOGY, v. 11, . (13/08216-2)
RODRIGUES, DANIEL; COSTA, TIAGO J.; SILVA, JOSIANE F.; NETO, JOSE TELES DE OLIVEIRA; ALVES, JULIANO V.; FEDOCE, ALINE G.; COSTA, RAFAEL MENEZES; TOSTES, RITA C.. Aldosterone Negatively Regulates Nrf2 Activity: An Additional Mechanism Contributing to Oxidative Stress and Vascular Dysfunction by Aldosterone. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 22, n. 11, . (13/08216-2, 18/05298-1)
CEBINELLI, GUILHERME CESAR MARTELOSSI; DE LIMA, KALIL ALVES; SILVA CASTANHEIRA, FERNANDA VARGAS E; HIROKI, CARLOS HIROJI; MONTEIRO, VALTER VINICIUS SILVA; DE LIMA, MIKHAEL HARUO FERNANDES; NASCIMENTO, DANIELE CARVALHO BERNARDO; ALVES FILHO, JOSE CARLOS; CUNHA, THIAGO MATTAR; CUNHA, FERNANDO DE QUEIROZ. CCR2-deficient mice are protected to sepsis by the disruption of the inflammatory monocytes emigration from the bone marrow. Journal of Leukocyte Biology, v. 109, n. 6, p. 1063-1070, . (13/08216-2)
CORSI-ZUELLI, FABIANA; DEAKIN, BILL; LIMA, MIKHAEL HARUO FERNANDES DE; QURESHI, OMAR; BARNES, NICHOLAS M.; UPTHEGROVE, RACHEL; LOUZADA-JUNIOR, PAULO; DEL-BEN, CRISTINA MARTA. T regulatory cells as a potential therapeutic target in psychosis? Current challenges and future perspectives. BRAIN, BEHAVIOR, & IMMUNITY - HEALTH, v. 17, p. 14-pg., . (12/05178-0, 13/08216-2, 20/02642-3, 19/13229-2, 21/07448-3)
TREVELIN, SILVIA CELLONE; SAG, CAN MARTIN; ZHANG, MIN; ALVES-FILHO, JOSE CARLOS; CUNHA, THIAGO MATTAR; DOS SANTOS, CELIO XAVIER; SAWYER, GRETA; MURRAY, THOMAS; BREWER, ALISON; MARTINS LAURINDO, FRANCISCO RAFAEL; et al. Endothelial Nox2 Limits Systemic Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4. Shock, v. 56, n. 2, p. 268-277, . (12/24677-7, 13/07937-8, 13/08216-2)
ZUCCOLI, GIULIANA S.; REIS-DE-OLIVEIRA, GUILHERME; GARBES, BRUNA; FALKAI, PETER; SCHMITT, ANDREA; NAKAYA, I, HELDER; MARTINS-DE-SOUZA, DANIEL. Linking proteomic alterations in schizophrenia hippocampus to NMDAr hypofunction in human neurons and oligodendrocytes. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, v. 271, n. 8, p. 1579-1586, . (18/01410-1, 17/25588-1, 13/08216-2, 19/00098-7, 12/19278-6, 17/50137-3, 18/14666-4)
POTJE, SIMONE R.; COSTA, TIAGO J.; FRAGA-SILVA, THAIS F. C.; MARTINS, RONALDO B.; BENATTI, MAIRA N.; ALMADO, CARLOS E. L.; DE SA, KEYLA S. G.; BONATO, VANIA L. D.; ARRUDA, EURICO; LOUZADA-JUNIOR, PAULO; et al. Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients. Life Sciences, v. 276, . (17/25116-2, 16/21239-0, 13/08216-2, 20/05270-0)
DE SOUZA, DEBORA MARIA SOARES; SILVA, MARIA CLAUDIA; FARIAS, SILVIA ELVIRA BARROS; MENEZES, ANA PAULA DE J.; MILANEZI, CRISTIANE MARIA; LUCIO, KARINE DE P.; PAIVA, NIVIA CAROLINA N.; DE ABREU, PAULA MELO; COSTA, DANIELA CALDEIRA; PINTO, KELERSON MAURO DE CASTRO; et al. Diet Rich in Lard Promotes a Metabolic Environment Favorable to Trypanosoma cruzi Growth. FRONTIERS IN CARDIOVASCULAR MEDICINE, v. 8, . (13/08216-2)
FACHIM, HELENE A.; CORSI-ZUELLI, FABIANA; LOUREIRO, CAMILA M.; IAMJAN, SRI-ARUN; SHUHAMA, ROSANA; JOCA, SAMIA; MENEZES, PAULO ROSSI; HEALD, ADRIAN; LOUZADA-JUNIOR, PAULO; DALTON, CAROLINE F.; et al. Early-life stress effects on BDNF DNA methylation in first-episode psychosis and in rats reared in isolation. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 108, . (12/05178-0, 12/17626-7, 13/11167-3, 17/00624-5, 13/08216-2, 19/13229-2, 17/17480-6, 15/02948-7)
PRADO, D. S.; DAMASCENO, L. E. A.; SONEGO, A. B.; ROSA, M. H.; MARTINS, T. V.; FONSECA, M. D. M.; CUNHA, T. M.; CUNHA, F. Q.; ALVES-FILHO, J. C.. Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism. International Immunopharmacology, v. 91, . (16/05377-3, 13/08216-2)
COSTA, TIAGO J.; BARROS, PAULA RODRIGUES; ARCE, CRISTINA; SANTOS, JEIMISON DUARTE; DA SILVA-NETO, JULIO; EGEA, GUSTAVO; PAULA DANTAS, ANA; TOSTES, RITA C.; JIMENEZ-ALTAYO, FRANCESC. The homeostatic role of hydrogen peroxide, superoxide anion and nitric oxide in the vasculature. Free Radical Biology and Medicine, v. 162, p. 615-635, . (13/08216-2)
DE CARVALHO, RENAN V. H.; LIMA-JUNIOR, DJALMA S.; DE OLIVEIRA, V, CAROLINE; ZAMBONI, DARIO S.. Endosymbiotic RNA virus inhibits Leishmania-induced caspase-11 activation. ISCIENCE, v. 24, n. 1, . (19/11342-6, 13/08216-2, 18/14398-0)
ZAMBONI, DARIO S.; SACKS, DAVID L.. Inflammasomes and Leishmania: in good times or bad, in sickness or in health. Current Opinion in Microbiology, v. 52, p. 70-76, . (13/08216-2, 14/04684-4)
SILVA, BRUNA M.; GOMES, GIOVANNI F.; VERAS, FLAVIO P.; CAMBIER, SEPPE; SILVA, GABRIEL V. L.; QUADROS, ANDREZA U.; CAETITE, DIEGO B.; NASCIMENTO, DANIELE C.; SILVA, CAMILLA M.; SILVA, JULIANA C.; et al. C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps. Journal of Clinical Investigation, v. 133, n. 12, p. 18-pg., . (13/08216-2, 20/04860-8, 18/10990-1)
DE LIMA, MIKHAEL HARUO FERNANDES; MACHADO, CAIO CAVALCANTE; NASCIMENTO, DANIELE CARVALHO; SILVA, CAMILA MEIRELLES S.; TOLLER-KAWAHISA, JULIANA ESCHER; RODRIGUES, TAMARA SILVA; VERAS, FLAVIO PROTASSIO; PONTELLI, MARJORIE CORNEJO; CASTRO, ITALO A.; ZAMBONI, DARIO SIMOES; et al. The TIGIT+ T regulatory cells subset associates with nosocomial infection and fatal outcome in COVID-19 patients under mechanical ventilation. SCIENTIFIC REPORTS, v. 13, n. 1, p. 12-pg., . (13/08216-2, 20/02642-3)
BONILHA, CAIO SANTOS; VERAS, FLAVIO PROTASIO; CUNHA, FERNANDO DE QUEIROZ. NET-targeted therapy: effects, limitations, and potential strategies to enhance treatment efficacy. TRENDS IN PHARMACOLOGICAL SCIENCES, v. 44, n. 9, p. 13-pg., . (13/08216-2, 21/09539-6, 20/05601-6)
RODRIGUES, TAMARA S.; CAETANO, CAMILA C. S.; DE SA, KEYLA S. G.; ALMEIDA, LETICIA; BECERRA, AMANDA; GONCALVES, AUGUSTO, V; LOPES, LETICIA DE SOUSA; OLIVEIRA, SAMUEL; MASCARENHAS, DANIELLE P. A.; BATAH, SABRINA S.; et al. CASP4/11 Contributes to NLRP3 Activation and COVID-19 Exacerbation. Journal of Infectious Diseases, v. 227, n. 12, p. 12-pg., . (13/08216-2, 20/04964-8, 19/11342-6)
COSTA, TIAGO J.; BARROS, PAULA R.; DUARTE, DIEGO A.; SILVA-NETO, JULIO A.; HOTT, SARA CRISTINA; SANTOS-SILVA, THAMYRIS; COSTA-NETO, CLAUDIO M.; V. GOMES, FELIPE; AKAMINE, ELIANA H.; MCCARTHY, CAMERON G.; et al. Carotid dysfunction in senescent female mice is mediated by increased a1A-adrenoceptor activity and COX-derived vasoconstrictor prostanoids. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 324, n. 4, p. 13-pg., . (13/08216-2, 17/25116-2)
PUHL, ANA C.; GOMES, GIOVANNI F.; DAMASCENO, SAMARA; FRITCH, ETHAN J.; LEVI, JAMES A.; JOHNSON, NICOLE J.; SCHOLLE, FRANK; PREMKUMAR, LAKSHMANANE; HURST, BRETT L.; LEE-MONTIEL, FELIPE; et al. Vandetanib Blocks the Cytokine Storm in SARS-CoV-2-Infected Mice. ACS OMEGA, v. 7, n. 36, p. 10-pg., . (13/08216-2, 20/04860-8)
CORSI-ZUELLI, FABIANA; HENRIQUES SCHNEIDER, AYDA; SANTOS-SILVA, THAMYRIS; MARCELINO LOUREIRO, CAMILA; SHUHAMA, ROSANA; ROSSI MENEZES, PAULO; SILVEIRA GUIMARAES, FRANCISCO; VILLELA GOMES, FELIPE; QUEIROZ CUNHA, FERNANDO; LOUZADA, PAULO; et al. Increased blood neutrophil extracellular traps (NETs) associated with early life stress: translational findings in recent-onset schizophrenia and rodent model. TRANSLATIONAL PSYCHIATRY, v. 12, n. 1, p. 11-pg., . (13/08216-2, 13/11167-3, 18/17597-3, 12/05178-0, 19/19190-0, 19/13229-2, 21/07448-3, 20/15752-1, 17/24304-0)
OLIVEIRA DA COSTA, LORENA CARLA; GARDINASSI, LUIZ GUSTAVO; VERAS, FLAVIO PROTASIO; MILANEZI, CRISTIANE; ZAMBELLI RAMALHO, LEANDRA NAIRA; BENEVIDES, LUCIANA; ALVES-FILHO, JOSE CARLOS; DA SILVA, JOAO SANTANA; SOUZA, CACILDA DA SILVA. Expression of B lymphocyte-induced maturation protein 1 (Blimp-1) in keratinocyte and cytokine signalling drives human Th17 response in psoriasis. ARCHIVES OF DERMATOLOGICAL RESEARCH, v. N/A, p. 10-pg., . (13/08216-2)
SCHNEIDER, AYDA HENRIQUES; TAIRA, THAISE MAYUMI; PUBLIO, GABRIEL AZEVEDO; PRADO, DOUGLAS DA SILVA; YABUTA, PAULA BARBIM DONATE; DOS SANTOS, JESSICA CRISTINA; MACHADO, CAIO CAVALCANTE; DE SOUZA, FLAVIO FALCAO LIMA; VENTURINI, LUCAS GABRIEL RODRIGUES; DE OLIVEIRA, RENE DONIZETI RIBEIRO; et al. Neutrophil extracellular traps mediate bone erosion in rheumatoid arthritis by enhancing RANKL-induced osteoclastogenesis. British Journal of Pharmacology, v. N/A, p. 18-pg., . (13/08216-2, 19/19190-0)
RODRIGUES, TAMARA S.; ZAMBONI, DARIO S.. Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation. CURRENT OPINION IN IMMUNOLOGY, v. 84, p. 6-pg., . (13/08216-2, 20/04964-8, 19/11342-6)
DE SA, KEYLA S. G.; AMARAL, LUANA A.; RODRIGUES, TAMARA S.; ISHIMOTO, ADRIENE Y.; DE ANDRADE, WARRISON A. C.; DE ALMEIDA, LETICIA; FREITAS-CASTRO, FELIPE; BATAH, SABRINA S.; OLIVEIRA, SERGIO C.; PASTORELLO, MONICA T.; et al. Gasdermin-D activation promotes NLRP3 activation and host resistance to Leishmania infection. NATURE COMMUNICATIONS, v. 14, n. 1, p. 19-pg., . (13/08216-2, 18/14398-0, 19/11342-6)
SACRAMENTO, LAIS AMORIM; CUNHA, FERNANDO Q.; DE ALMEIDA, ROQUE PACHECO; DA SILVA, JOAO SANTANA; CARREGARO, VANESSA. Protective Role of 5-Lipoxigenase during Leishmania infantum Infection Is Associated with Th17 Subset. BIOMED RESEARCH INTERNATIONAL, v. 2014, p. 12-pg., . (13/08216-2, 12/14524-9)
CUNHA, LARISSA D.; ZAMBONI, DARIO S.. Recognition of Legionella pneumophila nucleic acids by innate immune receptors. Microbes and Infection, v. 16, n. 12, p. 6-pg., . (13/08216-2, 14/04684-4, 12/09363-6)
PERES, RAPHAEL SANCHES; LIEW, FOO Y.; TALBOT, JHIMMY; CARREGARO, VANESSA; OLIVEIRA, RENE D.; ALMEIDA, SERGIO L.; FRANCA, RAFAEL F. O.; DONATE, PAULA B.; PINTO, LARISSA G.; FERREIRA, FLAVIA I. S.; et al. Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 112, n. 8, p. 6-pg., . (13/08216-2, 11/19670-0)
ZAMBONI, DARIO S.; LIMA-JUNIOR, DJALMA S.. Inflammasomes in host response to protozoan parasites. IMMUNOLOGICAL REVIEWS, v. 265, n. 1, p. 16-pg., . (13/08216-2, 14/04684-4)
XAVIER-ELSAS, PEDRO; DE LUCA, BIANCA; QUETO, TULIO; VIEIRA, BRUNO MARQUES; MASID-DE-BRITO, DANIELA; DAHAB, ELIZABETH CHEN; ALVES FILHO, JOSE CARLOS; CUNHA, FERNANDO Q.; GASPAR-ELSAS, MARIA IGNEZ C.. Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation. Mediators of Inflammation, v. 2015, p. 11-pg., . (13/08216-2)
LOUREIRO, CAMILA M.; FACHIM, HELENE A.; CORSI-ZUELLI, FABIANA; SHUHAMA, ROSANA; MENEZES, PAULO R.; DALTON, CAROLINE F.; DEL-BEN, CRISTINA M.; REYNOLDS, GAVIN P.; LOUZADA-JUNIOR, PAULO. The relationship of childhood trauma and DNA methylation of NMDA receptor genes in first-episode schizophrenia. Epigenomics, v. 13, n. 12, p. 927-937, . (12/05178-0, 13/11167-3, 17/00624-5, 16/12195-9, 19/13229-2, 15/02948-7, 13/08216-2)
CICALESE, STEPHANIE M.; DA SILVA, JOSIANE FERNANDES; PRIVIERO, FERNANDA; WEBB, R. CLINTON; EGUCHI, SATORU; TOSTES, RITA C.. Vascular Stress Signaling in Hypertension. Circulation Research, v. 128, n. 7, p. 969-992, . (13/08216-2, 16/16207-1)

Please report errors in scientific publications list using this form.
X

Report errors in this page


Error details: