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Isolation of keratinase microorganism producer, optimization of culture medium for enzyme production and physical-chemical characterization of pure enzyme

Grant number: 05/02712-1
Support Opportunities:Regular Research Grants
Start date: July 01, 2006
End date: June 30, 2008
Field of knowledge:Biological Sciences - Microbiology - Applied Microbiology
Principal Investigator:Jonas Contiero
Grantee:Jonas Contiero
Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil

Abstract

Keratinases (EC 3.4.99.11) are proteolitic enzymes that are capable of degrading Keratin. These are insoluble proteins present at hight levels in feathers, wool, hair, hooves and nails. Keratinases have an important use in the poultry processing because a great potential use of protein and amino acids for animal nutrition. Keratinases of microorganisms may be useful in the biotechnological clean-up of keratin-containing wastes such as feather and hair, thereby enhancing the nutritional quality of feather meal, and in the leather industry for removal of hair from hides. So far, a myriad of keratinolytic micro-organisms, mostly bacteria and fungi, have been reported. (AU)

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