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Impact of the implementation of a ‘standard operating procedure’ in sepsis mortality rates in public hospitals at São Paulo

Abstract

Considering national data, Brazilian sepsis mortality rates are very high, mainly in public hospitals from the Unified Health System (SUS). This mortality rate is much higher than the reported world mortality. This justifies actions aiming to reduce such rates. Surviving Sepsis Campaign is an international initiative devoted to implement guidelines for clinical management of these patients. The objective of this study is to determine severe sepsis/septic shock prevalence and baseline mortality in nine public hospitals at São Paulo, as well as the baseline compliance to the guidelines of treatment, and to evaluate the impact of the implementation of an education program and standard operating procedure, based on SSC guidelines, in the treatment adequacy and mortality rates. The study will be divided in three phases with 24-months duration. Prevalence, compliance and mortality will be compared before and after the intervention. Positive results will demonstrate the efficacy of this strategy and can result in a model to be applied in other public Brazilian institutions. In this way, the present study can benefit patients treated in SUS, contributing to a reduction in Brazilian sepsis mortality rates. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MACHADO, FLAVIA RIBEIRO; FERREIRA, ELAINE MARIA; SCHIPPERS, PIERRE; DE PAULA, ILUSCA CARDOSO; VENDRAME SAES, LETICIA SANDRE; DE OLIVEIRA, JR., FRANCISCO IVANILDO; TUMA, PAULA; NOGUEIRA FILHO, WILSON; PIZA, FELIPE; GUARE, SANDRA; et al. Implementation of sepsis bundles in public hospitals in Brazil: a prospective study with heterogeneous results. CRITICAL CARE, v. 21, . (09/53227-7)