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Drug abuse among pregnant adolescents

Grant number: 00/10293-5
Support type:Research Projects - Thematic Grants
Duration: February 01, 2001 - July 31, 2007
Field of knowledge:Health Sciences - Medicine - Maternal and Child Health
Principal Investigator:Ronaldo Laranjeira
Grantee:Ronaldo Laranjeira
Home Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
Co-Principal Investigators:Ruth Guinsburg


Teenager pregnancy and drug abuse by pregnant women are cause of concern regarding the mothers and their babies. Besides clinical and obstetrical problems, newborn infants exposed in-utero to drugs are at greater risk of neonatal and infant morbidity and mortality. Neuro-behavioral problems of these infants during the neonatal period, and growth and developmental deficits during the childhood are of special concern. The aim of this study is to verify the prevalence of drug abuse among teenager pregnant women assisted in a 3rd level Maternity of São Paulo City and to define their demographic, social, and psychopathological characteristics. Also, this study's goal is to analyze obstetrical, fetal and neonatal outcomes of the drug abusing of mothers and their infants. Questionnaires will be, applied to the mother soon after delivery and information will be checked with toxicological screening tests in mothers hair and infants meconium. The newborn infants will be assessed clinically and neurologically. The neurological and behavioral exam, will be performed by a specific tool recently developed. The results of this study may help the implementation of preventive measures to decrease the drug abuse during pregnancy of teenager women and the creation facilities to take care of the specific needs of the infants exposed in utero to drugs. (AU)

Scientific publications (9)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE MORAES BARROS, MARINA CARVALHO; MITSUHIRO, SANDRO SENDIM; CHALEM, ELISA; LARANJEIRA, RONALDO RAMOS; GUINSBURG, RUTH. Depression during gestation in adolescent mothers interferes with neonatal neurobehavior. Revista Brasileira de Psiquiatria, v. 35, n. 4, p. 353-359, OCT-DEC 2013. Web of Science Citations: 3.
CHALEM, ELISA; MITSUHIRO, SANDRO S.; MANZOLLI, PATRICIA; BARROS, MARINA C. M.; GUINSBURG, RUTH; SASS, NELSON; LARANJEIRA, RONALDO; FERRI, CLEUSA P. Underdetection of Psychiatric Disorders During Prenatal Care: A Survey of Adolescents in Sao Paulo, Brazil. JOURNAL OF ADOLESCENT HEALTH, v. 50, n. 1, p. 93-96, JAN 2012. Web of Science Citations: 4.
BARROS, MARINA C. M.; MITSUHIRO, SANDRO S.; CHALEM, ELISA; LARANJEIRA, RONALDO R.; GUINSBURG, RUTH. Prenatal tobacco exposure is related to neurobehavioral modifications in infants of adolescent mothers. Clinics, v. 66, n. 9, p. 1597-1603, 2011. Web of Science Citations: 5.
BARROS, MARINA C. M.; MITSUHIRO, SANDRO; CHALEM, ELISA; LARANJEIRA, RONALDO R.; GUINSBURG, RUTH. Neurobehavior of Late Preterm Infants of Adolescent Mothers. NEONATOLOGY, v. 99, n. 2, p. 133-139, 2011. Web of Science Citations: 13.
DE MORAES BARROS‚ M.C.; GUINSBURG‚ R.; MITSUHIRO‚ S.; CHALEM‚ E.; LARANJEIRA‚ R.R. Neurobehavioral profile of healthy full-term newborn infants of adolescent mothers. EARLY HUMAN DEVELOPMENT, v. 84, n. 5, p. 281-287, 2008.
CHALEM, ELISA; MITSUHIRO, SANDRO SENDIN; FERRI, CLEUSA P.; BARROS, MARINA CARVALHO MORAES; GUINSBURG, RUTH; LARANJEIRA, RONALDO. Gravidez na adolescência: perfil sócio-demográfico e comportamental de uma população da periferia de São Paulo, Brasil. Cadernos de Saúde Pública, v. 23, n. 1, p. 177-186, jan. 2007.
FERRI‚ C.; MITSUHIRO‚ S.; BARROS‚ M.; CHALEM‚ E.; GUINSBURG‚ R.; PATEL‚ V.; PRINCE‚ M.; LARANJEIRA‚ R. The impact of maternal experience of violence and common mental disorders on neonatal outcomes: a survey of adolescent mothers in Sao Paulo‚ Brazil. BMC PUBLIC HEALTH, v. 7, n. 1, p. 209, 2007.
MITSUHIRO‚ S.S.; CHALEM‚ E.; BARROS‚ M.C.M.; GUINSBURG‚ R.; LARANJEIRA‚ R. Prevalence of cocaine and marijuana use in the last trimester of adolescent pregnancy: Socio-demographic‚ psychosocial and behavioral characteristics. ADDICTIVE BEHAVIORS, v. 32, n. 2, p. 392-397, 2007.
SANDRO SENDIN MITSUHIRO; ELISA CHALEM; MARINA MORAES BARROS; RUTH GUINSBURG; RONALDO LARANJEIRA. Teenage pregnancy: use of drugs in the third trimester and prevalence of psychiatric disorders. Revista Brasileira de Psiquiatria, v. 28, n. 2, p. -, Jun. 2006.

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