Preeclampsia is an important cause of glomerulonephritis in the world and it seems to be associated to future risk of nephropathy and cardiovascular disease. Several studies indicate that preeclampsia is an independent risk factor for long-term complications such as chronic hypertension, stroke, metabolic syndrome and glomerulonephritis. Investigate the history of preeclampsia is important to follow-up, early diagnosis and treatment of cardiovascular or renal disorders and should be part of the clinical practice.This project is a continuation of the same research group previously financed by Fapesp which evaluated the podocyturia in preeclampsia. The objective is to investigate future risk of cardiovascular and chronic kidney disease in women with history of preeclampsia by clinical, laboratory and epidemiologic criteria. The patients will be called, examined and submitted to bioimpedance test, dosage of albuminuria, albumin/creatinine ratio, urinary protein/creatinine, urinary retinol transporter protein, podocyturia, serum creatinine, urea , insulin, activated protein C, uric acid, triglycerides, cholesterol, cystatin C, complete blood count, homocysteine, glucose, vitamin D, vascular endothelial growth factor and soluble receptor for vascular endothelial growth factor. (AU)
Articles published in Agência FAPESP Newsletter about the research grant:
FACCA, THAIS ALQUEZAR;
PEREIRA SABINO, AMELIA RODRIGUES;
PASSOS, MICHELLE TIVERON;
DOS SANTOS, LARISSA FATIMA;
BROSCO FAMA, EDUARDO AUGUSTO;
NISHIDA, SONIA KIYOMI;
Pregnancy as an early stress test for cardiovascular and kidney disease diagnosis.
PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH,
Web of Science Citations: 5.