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Development of ceramic composites of Si3N4-SiO2-CaO system for bone compatibility

Grant number: 15/02265-7
Support type:Regular Research Grants
Duration: July 01, 2015 - June 30, 2017
Field of knowledge:Engineering - Materials and Metallurgical Engineering
Principal Investigator:Cecília Chaves Guedes e Silva
Grantee:Cecília Chaves Guedes e Silva
Home Institution: Instituto de Pesquisas Energéticas e Nucleares (IPEN). Secretaria de Desenvolvimento Econômico (São Paulo - Estado). São Paulo , SP, Brazil
Assoc. researchers:Andrea Cecilia Dorión Rodas ; Olga Zazuco Higa

Abstract

Considering the ceramic materials investigated for biomedical applications, those based on silicon nitride have presented great potentiality owing to the high mechanical strength, relatively high fracture toughness and low density. However, the biocompatibility of these ceramics depends on the features of intergranular phases usually present and required to produce the final components. Hence, the present project will contribute to the development of silicon nitride containing a second phase depending upon the SiO2-CaO system. Silica and calcia will be added to the initial powder of silicon nitride to promote the biocomposite consolidation with great mechanical properties after sintering. Moreover, it is expected to obtain a bioactive material due to the Si-OH groups formed during the contact with body fluids, promoting deposition of apatite on the surface. The influence of different oxides amounts on the biocomposites will be evaluated in terms of densification, microstructure, mechanical properties and in vitro bioactivity. (AU)

Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DAGUANO, JULIANA K. M. B.; MILESI, MARIANA T. B.; RODAS, ANDREA C. D.; WEBER, ALINE F.; SARKIS, JORGE E. S.; HORTELLANI, MARCOS A.; ZANOTTO, EDGAR D. In vitro biocompatibility of new bioactive lithia-silica glass-ceramics. Materials Science & Engineering C-Materials for Biological Applications, v. 94, p. 117-125, JAN 1 2019. Web of Science Citations: 3.
T. S. FERREIRA; F. M. S. CARVALHO; C. C. GUEDES-SILVA. Densification and microstructure of Si3N4-TiN ceramic composites. Cerâmica, v. 65, p. 87-91, Jan. 2019.
GUEDES-SILVA, CECILIA CHAVES; DORION RODAS, ANDREA CECILIA; SILVA, ANTONIO CARLOS; RIBEIRO, CHRISTIANE; DE SOUZA CARVALHO, FLAVIO MACHADO; HIGA, OLGA ZAZUCO; FERREIRA, THIAGO DOS SANTOS. Microstructure, Mechanical Properties and in vitro Biological Behavior of Silicon Nitride Ceramics. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 21, n. 6 2018. Web of Science Citations: 0.
JURASKI, AMANDA DE CASTRO; DORION RODAS, ANDREA CECILIA; ELSAYED, HAMADA; BERNARDO, ENRICO; SOARES, VIVIANE OLIVEIRA; DAGUANO, JULIANA. The In Vitro Bioactivity, Degradation, and Cytotoxicity of Polymer-Derived Wollastonite-Diopside Glass-Ceramics. MATERIALS, v. 10, n. 4 APR 2017. Web of Science Citations: 7.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.