Defining the relationship between sex hormones, protein quality control and male fertility

• Grant number: 15/50011-4
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2015
• End date: January 31, 2018
• Field of knowledge: Biological Sciences - Pharmacology - Biochemical and Molecular Pharmacology
• Agreement: Durham University
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Maria Christina Werneck de Avellar
• Grantee: Maria Christina Werneck de Avellar
• Principal researcher abroad: Adam Maurice Benhaam
• Institution abroad: Durham University (DU), England
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated research grant: 14/19378-6 - Expression, behavioral effects and fertility parameters of beta-defensins and neuropeptide Y in a mouse model of post-traumatic stress disorder (PTSD) related to neurosteroids profile, AP.R

Abstract

Our cross-disciplinary research proposal aims to increase our understanding of the basic biochemistry and pharmacology that underpins human health, fertility and reproduction. One in six couples are affected by infertility and in ~ 45% the infertility is (AU)