Development of electrochemical sensors and biosensors for different analytical purposes

• Grant number: 15/19099-2
• Support Opportunities: Regular Research Grants
• Duration: December 01, 2015 - November 30, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Bruno Campos Janegitz
• Grantee: Bruno Campos Janegitz
• Host Institution: Centro de Ciências Agrárias (CCA). Universidade Federal de São Carlos (UFSCAR). Araras , SP, Brazil

Abstract

In recent years, new analytical methods have been proposed for easy and quick detection of different compounds of interest. In this project, we will develop new architectures for electrochemical sensors and biosensors. Biosensors will be prepared for different diseases: DNA sensor for mutation detection predisposition related to anemia; immunosensor for DJ-1, protein related with Parkinson disease. Moreover, it will be proposed biosensors using tyrosinase and acetylcholinesterase for the determination of pesticides and phenols for environmental analysis. In addition, it will be proposed nanostructured sensors for determination of pesticides and heavy metals in natural water and wastewater samples in order to obtain low cost devices with high sensitivity for field application. (AU)

Scientific publications

(25)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

JANEGITZ, BRUNO CAMPOS; SILVA, TIAGO ALMEIDA; WONG, ADEMAR; RIBOVSKI, LAIS; VICENTINI, FERNANDO CAMPANHA; TABOADA SOTOMAYOR, MARIA DEL PILAR; FATIBELLO-FILHO, ORLANDO. The application of graphene for in vitro and in vivo electrochemical biosensing. BIOSENSORS & BIOELECTRONICS, v. 89, n. 1, SI, p. 224-233, MAR 15 2017. (15/19099-2)

SILVA, TIAGO ALMEIDA; MORAES, FERNANDO CRUZ; JANEGITZ, BRUNO CAMPOS; FATIBELLO-FILHO, ORLANDO. Electrochemical Biosensors Based on Nanostructured Carbon Black: A Review. Journal of Nanomaterials, 2017. (16/12926-3, 15/19099-2)

VICENTINI, FERNANDO CAMPANHA; JANEGITZ, BRUNO C.; BONIFACIO, VIVIANE G.; FATIBELLO-FILHO, ORLANDO; MARCOLINO-JUNIOR, LUIZ H.. Novel flow injection spectrophotometric determination of ranitidine in pharmaceuticals. Canadian Journal of Chemistry, v. 94, n. 7, p. 604-607, JUL 2016. (15/19099-2)

SIMIONI, NATALIA BORTOLUCCI; OLIVEIRA, GEISER GABRIEL; VICENTINI, FERNANDO CAMPANHA; LANZA, MARCOS R. V.; JANEGITZ, BRUNO C.; FATIBELLO-FILHO, ORLANDO. Nanodiamonds stabilized in dihexadecyl phosphate film for electrochemical study and quantification of codeine in biological and pharmaceutical samples. DIAMOND AND RELATED MATERIALS, v. 74, p. 191-196, APR 2017. (15/19099-2, 13/16770-0)

RIBOVSKI, LAIS; ZUCOLOTTO, VALTENCIR; JANEGITZ, BRUNO C.. A label-free electrochemical DNA sensor to identify breast cancer susceptibility. Microchemical Journal, v. 133, p. 37-42, JUL 2017. (15/19099-2)

JODAR, LETICIA VIEIRA; ORZARI, LUIZ OTAVIO; ORTOLANI, TULIO STORTI; ASSUMPCAO, MONICA H. M. T.; VICENTINI, FERNANDO C.; JANEGITZ, BRUNO C.. Electrochemical Sensor Based on Casein and Carbon Black for Bisphenol A Detection. Electroanalysis, v. 31, n. 11, JULY 2019. (15/19099-2, 17/21898-6)

BRAZACA, LAIS C.; BRAMORSKI, CAMILA B.; CANCINO-BERNARDI, JULIANA; CRUZ-MACHADO, SANSERAY DA SILVEIRA; MARKUS, REGINA P.; JANEGITZ, BRUNO C.; ZUCOLOTTO, VALTENCIR. An antibody-based platform for melatonin quantification. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 171, p. 94-100, NOV 1 2018. (13/13691-1, 15/02623-0, 15/19099-2)

ORZARI, LUIZ O.; SANTOS, FABRICIO A.; JANEGITZ, BRUNO C.. Manioc starch thin film as support of reduced graphene oxide: A novel architecture for electrochemical sensors. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 823, p. 350-358, AUG 15 2018. (17/21898-6, 15/19099-2, 16/12697-4)

DELGADO, KARINA P.; RAYMUNDO-PEREIRA, PAULO A.; CAMPOS, ANDERSON M.; OLIVEIRA, JR., OSVALDO N.; JANEGITZ, BRUNO C.. Ultralow Cost Electrochemical Sensor Made of Potato Starch and Carbon Black Nanoballs to Detect Tetracycline in Waters and Milk. Electroanalysis, v. 30, n. 9, p. 2153-2159, SEP 2018. (16/01919-6, 16/19885-0, 13/14262-7, 15/19099-2)

MAURUTO DE OLIVEIRA, GABRIELA C.; DE PALMA, ELISANGELA P.; KUNITA, MARCOS H.; MEDEIROS, ROBERTA ANTIGO; DE MATOS, ROBERTO; FRANCISCO, KELLY ROBERTA; JANEGITZ, BRUNO C.. Tapioca Biofilm Containing Nitrogen-doped Titanium Dioxide Nanoparticles for Electrochemical Detection of 17-beta Estradiol. Electroanalysis, v. 29, n. 11, p. 2638-2645, NOV 2017. (16/04743-6, 15/19099-2)

WONG, ADEMAR; SILVA, TIAGO A.; CAETANO, FABIO R.; BERGAMINI, MARCIO F.; MARCOLINO-JUNIOR, LUIZ H.; FATIBELLO-FILHO, ORLANDO; JANEGITZ, BRUNO C.. An Overview of Pesticide Monitoring at Environmental Samples Using Carbon Nanotubes-Based Electrochemical Sensors. C-JOURNAL OF CARBON RESEARCH, v. 3, n. 1, MAR 2017. (15/19099-2)

RIBOVSKI, LAIS; DOS SANTOS, FABRICIO A.; ZUCOLOTTO, VALTENCIR; JANEGITZ, BRUNO C.. Gold nanorods and poly(amido amine) dendrimer thin film for biosensing. Journal of Solid State Electrochemistry, v. 23, n. 5, p. 1581-1591, MAY 2019. (15/19099-2)

BRAZACA, LAIS C.; BRAMORSKI, CAMILA B.; CANCINO-BERNARDI, JULIANA; JANEGITZ, BRUNO C.; ZUCOLOTTO, VALTENCIR. A Genosensor for Sickle Cell Anemia Trait Determination. Electroanalysis, v. 29, n. 3, p. 773-777, MAR 2017. (15/19099-2)

BACCARIN, MARINA; SANTOS, FABRICIO A.; VICENTINI, FERNANDO C.; ZUCOLOTTO, VALTENCIR; JANEGITZ, BRUNO C.; FATIBELLO-FILHO, ORLANDO. Electrochemical sensor based on reduced graphene oxide/carbon black/chitosan composite for the simultaneous determination of dopamine and paracetamol concentrations in urine samples. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 799, p. 436-443, AUG 15 2017. (15/19099-2)

JANEGITZ, BRUNO CAMPOS; SILVA, TIAGO ALMEIDA; WONG, ADEMAR; RIBOVSKI, LAIS; VICENTINI, FERNANDO CAMPANHA; TABOADA SOTOMAYOR, MARIA DEL PILAR; FATIBELLO-FILHO, ORLANDO. The application of graphene for in vitro and in vivo electrochemical biosensing. BIOSENSORS & BIOELECTRONICS, v. 89, p. 10-pg., 2017-03-15. (15/19099-2)

JODAR, LETICIA VIEIRA; SANTOS, FABRICIO APARECIDO; ZUCOLOTTO, VALTENCIR; JANEGITZ, BRUNO CAMPOS. Electrochemical sensor for estriol hormone detection in biological and environmental samples. Journal of Solid State Electrochemistry, v. 22, n. 5, SI, p. 1431-1438, MAY 2018. (15/19099-2)

CAMARGO, ESSICA ROCHA; BACCARIN, MARINA; RAYMUNDO-PEREIRA, PAULO A.; CAMPOS, ANDERSON M.; OLIVEIRA, GEISER G.; FATIBELLO-FILHO, ORLANDO; OLIVEIRA, JR., OSVALDO N.; JANEGITZ, BRUNO C.. Electrochemical biosensor made with tyrosinase immobilized in a matrix of nanodiamonds and potato starch for detecting phenolic compounds. Analytica Chimica Acta, v. 1034, p. 137-143, NOV 30 2018. (16/01919-6, 13/14262-7, 15/19099-2)

DE FIGUEIREDO-FILHO, LUIZ C. S.; BACCARIN, MARINA; JANEGITZ, BRUNO C.; FATIBELLO-FILHO, ORLANDO. A disposable and inexpensive bismuth film minisensor for a voltammetric determination of diquat and paraquat pesticides in natural water samples. SENSORS AND ACTUATORS B-CHEMICAL, v. 240, p. 749-756, MAR 2017. (15/19099-2)

PEREIRA, TAMIRES DOS SANTOS; MAURUTO DE OLIVEIRA, GABRIELA C.; SANTOS, FABRICIO APARECIDO; RAYMUNDO-PEREIRA, PAULO A.; OLIVEIRA, JR., OSVALDO N.; JANEGITZ, BRUNO CAMPOS. Use of zein microspheres to anchor carbon black and hemoglobin in electrochemical biosensors to detect hydrogen peroxide in cosmetic products, food and biological fluids. Talanta, v. 194, p. 737-744, MAR 1 2019. (17/17572-8, 16/01919-6, 13/14262-7, 16/18270-2, 15/19099-2, 16/04743-6)

RAYMUNDO-PEREIRA, PAULO A.; CAMPOS, ANDERSON M.; VICENTINI, FERNANDO C.; JANEGITZ, BRUNO C.; MENDONCA, CAMILA D.; FURINI, LEONARDO N.; BOAS, NAIZA V.; CALEGARO, MARCELO L.; CONSTANTINO, CARLOS J. L.; MACHADO, SERGIO A. S.; et al. Sensitive detection of estriol hormone in creek water using a sensor platform based on carbon black and silver nanoparticles. Talanta, v. 174, p. 652-659, NOV 1 2017. (16/01919-6, 14/05197-0, 13/14262-7, 16/12759-0, 15/19099-2, 12/17689-9)

VICENTINI, FERNANDO CAMPANHA; RAYMUNDO-PEREIRA, PAULO A.; JANEGITZ, BRUNO C.; MACHADO, SERGIO A. S.; FATIBELLO-FILHO, ORLANDO. Nanostructured carbon black for simultaneous sensing in biological fluids. SENSORS AND ACTUATORS B-CHEMICAL, v. 227, p. 610-618, MAY 2016. (12/17689-9, 15/19099-2, 12/02877-4, 13/16770-0)

BRAZACA, LAIS C.; JANEGITZ, BRUNO C.; CANCINO-BERNARDI, JULIANA; ZUCOLOTTO, VALTENCIR. Transmembrane Protein-Based Electrochemical Biosensor for Adiponectin Hormone Quantification. CHEMELECTROCHEM, v. 3, n. 6, p. 1006-1011, JUN 2016. (15/19099-2, 13/10608-6)

ORZARI, LUIZ OTAVIO; DE ARAUJO ANDREOTTI, ISABELA APARECIDA; BERGAMINI, MARCIO FERNANDO; MARCOLINO JUNIOR, LUIZ HUMBERTO; JANEGITZ, BRUNO CAMPOS. Disposable electrode obtained by pencil drawing on corrugated fiberboard substrate. SENSORS AND ACTUATORS B-CHEMICAL, v. 264, p. 20-26, JUL 1 2018. (16/12697-4, 15/19099-2)

JODAR, LETICIA VIEIRA; SANTOS, FABRICIO APARECIDO; ZUCOLOTTO, VALTENCIR; JANEGITZ, BRUNO CAMPOS. Electrochemical sensor for estriol hormone detection in biological and environmental samples. Journal of Solid State Electrochemistry, v. 22, n. 5, p. 8-pg., 2018-05-01. (15/19099-2)

SILVA, TIAGO ALMEIDA; MORAES, FERNANDO CRUZ; JANEGITZ, BRUNO CAMPOS; FATIBELLO-FILHO, ORLANDO. Electrochemical Biosensors Based on Nanostructured Carbon Black: A Review. Journal of Nanomaterials, v. 2017, p. 14-pg., 2017-01-01. (15/19099-2, 16/12926-3)

Filed patent(s) as a result of this research project