Development of High Performance Bioelectrodes for Application in Miniaturized Biofuel Cell

• Grant number: 15/16672-3
• Support Opportunities: Regular Research Grants
• Duration: February 01, 2016 - January 31, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Principal Investigator: Frank Nelson Crespilho
• Grantee: Frank Nelson Crespilho
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil

Abstract

Nowadays, miniaturization of biofuel cells (BFCs) is the biggest challenge in bioelectronics, which is directly dependent on obtaining stable and efficient enzymatic bioelectrodes. Our Group has proposed that electrodes based on individual graphene sheets, as well as flexible carbon fibers (FCFs), produce the most efficient bioelectrodes reported so far, these being applied in implantable BFCs. Thus, in this project we will develop new electrodes for use in biocathodes and bioanodes, with the focus on developing two classes of bioeletrodos, one with the FCFs and other with individual graphene sheets. Besides the micromanipulation of the electrodes, the non-catalytic processes of charge transfer using the Marcus theory will be investigated. Finally, the viability of electrodes application BCs will be investigated by studying the bioelectrocatalysis, particularly for glucose oxidation and oxygen reduction in a physiological medium. (AU)

Scientific publications

(16)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

RODRIGUES, FERNANDO POSTALLI; MACEDO, LUCYANO J. A.; MAXIMO, LEANDRO N. C.; SALES, FERNANDA C. P. F.; DA SILVA, ROBERTO S.; CRESPILHO, FRANK N.. Real-time redox monitoring of a nitrosyl ruthenium complex acting as NO-donor agent in a single A549 cancer cell with multiplex Fourier-transform infrared microscopy. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, v. 96, p. 29-34, MAR 1 2020. (13/07829-0, 16/12707-0, 15/16672-3, 13/14262-7, 17/20493-2, 14/03964-3)

PEREIRA, ANDRESSA R.; LUZ, ROBERTO A. S.; LIMA, FILIPE C. D. A.; CRESPILHO, FRANK N.. Protein Oligomerization Based on Bronsted Acid Reaction. ACS CATALYSIS, v. 7, n. 4, p. 3082-3088, APR 2017. (15/16672-3, 13/19908-2, 13/14262-7)

PEREIRA, ANDRESSA R.; SEDENHO, GRAZIELA C.; DE SOUZA, JOAO C. P.; CRESPILHO, FRANK N.. Advances in enzyme bioelectrochemistry. Anais da Academia Brasileira de Ciências, v. 90, n. 1, 1, p. 825-857, 2018. (15/16672-3, 15/22973-6, 13/14262-7)

HASSAN, AYAZ; MACEDO, LUCYANO J. A.; DE SOUZA, JOAO C. P.; LIMA, FILIPE C. D. A.; CRESPILHO, FRANK N.. A combined Far-FTIR, FTIR Spectromicroscopy, and DFT Study of the Effect of DNA Binding on the [4Fe4S] Cluster Site in EndoIII. SCIENTIFIC REPORTS, v. 10, n. 1, FEB 6 2020. (17/20493-2, 13/14262-7, 15/16672-3, 16/25806-6)

PEREIRA, ANDRESSA R.; DE SOUZA, JOAO C. P.; GONCALVES, ANDRESSA D.; PAGNONCELLI, KAMILA C.; CRESPILHO, FRANK N.. Bioelectrooxidation of Ethanol Using NAD-Dependent Alcohol Dehydrogenase on Oxidized Flexible Carbon Fiber Arrays. Journal of the Brazilian Chemical Society, v. 28, n. 9, p. 10-pg., 2017-09-01. (13/14262-7, 13/19908-2, 15/16672-3)

PEREIRA, ANDRESSA R.; DE SOUZA, JOAO C. P.; GONCALVES, ANDRESSA D.; PAGNONCELLI, KAMILA C.; CRESPILHO, FRANK N.. Bioelectrooxidation of Ethanol Using NAD-Dependent Alcohol Dehydrogenase on Oxidized Flexible Carbon Fiber Arrays. Journal of the Brazilian Chemical Society, v. 28, n. 9, p. 1698-1707, SEP 2017. (15/16672-3, 13/14262-7, 13/19908-2)

MACEDO, LUCYANO J. A.; LIMA, FITIPE C. D. A.; AMORIM, RODRIGO G.; FREITAS, RAUL O.; YADAV, ANUR; IOST, RODRIGO M.; BALASUBRAMANIAN, KANNAN; CRESPILHO, FRANK N.. Interplay of non-uniform charge distribution on the electrochemical modification of graphene. NANOSCALE, v. 10, n. 31, p. 15048-15057, AUG 21 2018. (13/14262-7, 15/16672-3)

KHALID, MOHD.; HASSAN, AYAZ; HONORATO, ANA M. B.; CRESPILHO, FRANK N.; VARELA, HAMILTON. Nano-flocks of a bimetallic organic framework for efficient hydrogen evolution electrocatalysis. CHEMICAL COMMUNICATIONS, v. 54, n. 78, p. 11048-11051, OCT 7 2018. (13/14262-7, 13/16930-7, 15/16672-3, 16/25806-6, 17/00433-5)

KHALID, MOHD; HASSAN, AYAZ; HONORATO, ANA M. B.; CRESPILHO, FRANK N.; VARELA, HAMILTON. 8-Hydroxyquinoline-5-sulfonic acid on reduced graphene oxide layers as a metal-free electrode material for supercapacitor applications. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 847, AUG 15 2019. (13/14262-7, 15/16672-3, 13/16930-7, 16/25806-6, 17/00433-5)

MACEDO, LUCYANO J. A.; CRESPILHO, FRANK N.. Multiplex Infrared Spectroscopy Imaging for Monitoring Spatially Resolved Redox Chemistry. Analytical Chemistry, v. 90, n. 3, p. 1487-1491, FEB 6 2018. (13/14262-7, 15/16672-3)

BECHER, TIAGO B.; BRAGA, CAROLYNE B.; BERTUZZI, DIEGO L.; RAMOS, JR., MIGUEL D.; HASSAN, AYAZ; CRESPILHO, FRANK N.; ORNELAS, CATIA. The structure-property relationship in LAPONITE (R) materials: from Wigner glasses to strong self-healing hydrogels formed by non-covalent interactions. SOFT MATTER, v. 15, n. 6, p. 1278-1289, FEB 14 2019. (13/11519-7, 15/16672-3, 18/02093-0, 13/14262-7, 16/25806-6, 15/04929-0)

PAGNONCELLI, KAMILA C.; PEREIRA, ANDRESSA R.; SEDENHO, GRAZIELA C.; BERTAGLIA, THIAGO; CRESPILHO, FRANK N.. Ethanol generation, oxidation and energy production in a cooperative bioelectrochemical system. BIOELECTROCHEMISTRY, v. 122, p. 11-25, AUG 2018. (15/16672-3, 13/14262-7, 13/19908-2, 15/22973-6)

RODRIGO M. IOST; MARCCUS V.A. MARTINS; FRANK N. CRESPILHO. Dendritic Gold Nanoparticles Towards Transparent and Electroactive Electrodes. Anais da Academia Brasileira de Ciências, v. 91, n. 4, 2019-11-28. (15/16672-3, 09/12000-0, 13/04663-4, 13/14262-7)

ALI, MIAN A.; HASSAN, AYAZ; SEDENHO, GRAZIELA C.; GONCALVES, RENATO V.; CARDOSO, DANIEL R.; CRESPILHO, FRANK N.. Operando Electron Paramagnetic Resonance for Elucidating the Electron Transfer Mechanism of Coenzymes. Journal of Physical Chemistry C, v. 123, n. 26, p. 16058-16064, JUL 4 2019. (13/14262-7, 15/16672-3, 16/25806-6, 17/01189-0, 15/22973-6)

DE SOUZA, JOAO C. P.; SILVA, WANDERSON O.; LIMA, FABIO H. B.; CRESPILHO, FRANK N.. Enzyme activity evaluation by differential electrochemical mass spectrometry. CHEMICAL COMMUNICATIONS, v. 53, n. 60, p. 8400-8402, AUG 4 2017. (13/14262-7, 15/16672-3, 13/16930-7, 16/13323-0)

LUZ, ROBERTO A. S.; CRESPILHO, FRANK N.. Gold nanoparticle-mediated electron transfer of cytochrome c on a self-assembled surface. RSC ADVANCES, v. 6, n. 67, p. 62585-62593, 2016. (13/04663-4, 13/14262-7, 15/16672-3, 09/17898-4)