Advanced search
Start date
Betweenand
Related content

PREDICTIVE VALUE OF BIOMARKERS AND NEUROIMAGING IN LONG-TERM EVOLUTION OF POST-STROKE DEPRESSION AND COGNITIVE IMPAIRMENT IN EMMA STUDY

Abstract

Recent data shows that stroke is responsible for about 5.7 million deaths, of which 87% have been reported in countries with low and middle incomes. In Brazil, the stroke in association with hypertension was responsible for the occurrence of 52,000 deaths in 2012, and ranked as the third cause of mortality. The reported risk of death by stroke is two times higher in areas with low income status (SES) compared to areas with higher SES in São Paulo. Despite the impact of cerebrovascular disease as a major public health problem, few resources have been used in strategies to control risk factors, organization of public networks of medical care, and especially rehabilitation and support of patients affected by stroke. In addition to the physical and motor limitations, the patient post-stroke, can often develop neuropsychological changes as depressive symptoms and cognitive impairment that may progress to severe depression and dementia. It is estimated that the post-stroke depression can occur in around 30-50% of cases and is usually associated with a worsening of cognitive status, impaired recovery of motor function and increased mortality. In addition, post-stroke depression is also associated with a deterioration in the quality life. Therefore, we propose an extended evaluation in a sub-sample of prospective cohort of the EMMA study (Mortality and Morbidity Study of Stroke), which provides for monitoring the evolution of depression and cognitive impairment after stroke, and prognostic value of neuroimaging and biomarkers related to vascular injury in long term survival. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
Articles published in other media outlets (0 total):
More itemsLess items
VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (5)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BACCARO, ALESSANDRA; WANG, YUAN-PANG; BRUNONI, ANDRE RUSSOWSKY; CANDIDO, MIRIAM; CONFORTO, ADRIANA BASTOS; LEITE, CLAUDIA DA COSTA; LOTUFO, PAULO A.; BENSENOR, ISABELA M.; GOULART, ALESSANDRA C. Does stroke laterality predict major depression and cognitive impairment after stroke? Two-year prospective evaluation in the EMMA study. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 94, AUG 30 2019. Web of Science Citations: 1.
BACCARO, ALESSANDRA; WANG, YUAN-PANG; CANDIDO, MIRIAM; CONFORTO, ADRIANA BASTOS; BRUNONI, ANDRE RUSSOWSKY; LEITE, CLAUDIA DA COSTA; FILHO, GERALDO BUSATTO; LOTUFO, PAULO A.; BENSENOR, ISABELA M.; GOULART, ALESSANDRA CARVALHO. Post-stroke depression and cognitive impairment: Study design and preliminary findings in a Brazilian prospective stroke cohort (EMMA study). Journal of Affective Disorders, v. 245, p. 72-81, FEB 15 2019. Web of Science Citations: 3.
CASTRO, HERBERT H. G.; ALENCAR, AIRLANE PEREIRA; BENSENOR, ISABELA M.; LOTUFO, PAULO A.; GOULART, ALESSANDRA C. Multimorbidities Are Associated to Lower Survival in Ischaemic Stroke: Results from a Brazilian Stroke Cohort (EMMA Study). CEREBROVASCULAR DISEASES, v. 44, n. 3-4, p. 232-239, 2017. Web of Science Citations: 10.
GOULART, ALESSANDRA CARVALHO. ``EMMA Study: a Brazilian community-based cohort study of stroke mortality and morbidity{''}. São Paulo Medical Journal, v. 134, n. 6, p. 543-554, NOV-DEC 2016. Web of Science Citations: 1.
ALESSANDRA CARVALHO GOULART. "EMMA Study: a Brazilian community-based cohort study of stroke mortality and morbidity". São Paulo Medical Journal, v. 134, n. 6, p. -, Dez. 2016.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.