Advanced search
Start date

Antibiofilm and antimicrobial activity of rhamnolipids against food pathogenic bacteria

Grant number: 15/22414-7
Support type:Regular Research Grants
Duration: March 01, 2016 - February 28, 2018
Field of knowledge:Agronomical Sciences - Food Science and Technology
Principal Investigator:Marcia Nitschke
Grantee:Marcia Nitschke
Home Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil


Rhamnolipids (RL) are bacterial-derived surfactants showing very interesting properties to food industry not only as emulsifier agents but also due to their biodegradability, low toxicity and production using renewable substrates. The RL show potential on controlling microorganisms exhibiting antimicrobial activity and decreasing biofilm formation of food pathogens as Listeria monocytogenes and Salmonella spp. Owing to their amphiphilic nature, RL can also be useful on disrupting/removing established biofilms improving the efficiency of sanitization procedures. The aim of this project is to evaluate the remove of biofilms formed by food pathogenic bacteria using rhamnolipids, focusing on the effect of temperature, RL concentration and food matrix (milk). The mechanisms involved on biofilm disruption and antimicrobial activity of RL will be also investigated. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FERREIRA, JAKELINE DE FREITAS; VIEIRA, ESTEVAO ALAN; NITSCHKE, MARCIA. The antibacterial activity of rhamnolipid biosurfactant is pH dependent. Food Research International, v. 116, p. 737-744, FEB 2019. Web of Science Citations: 3.
SILVA, S. S. E; CARVALHO, J. W. P.; AIRES, C. P.; NITSCHKE, M. Disruption of Staphylococcus aureus biofilms using rhamnolipid biosurfactants. JOURNAL OF DAIRY SCIENCE, v. 100, n. 10, p. 7864-7873, OCT 2017. Web of Science Citations: 13.

Please report errors in scientific publications list by writing to: