Multi-user equipment approved in grant 2014/50489-9:Elastography ultrasound for safe research dimensions and organ texture in children - elastography

• Grant number: 15/26778-3
• Support Opportunities: Multi-user Equipment Program
• Duration: July 01, 2016 - June 30, 2018
• Field of knowledge: Health Sciences - Medicine - Maternal and Child Health
• Principal Investigator: Magda Maria Sales Carneiro-Sampaio
• Grantee: Magda Maria Sales Carneiro-Sampaio
• Host Institution: Instituto da Criança Professor Doutor Pedro de Alcantara (ICR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 14/50489-9 - Human thymus: development and diseases, AP.TEM
• EMU web page: http://icr.usp.br/elastografo
• Type of equipment: Caracterização de Materiais - Imageamento - Ultrassom; Caracterização e Análises de Amostras - Acústica - Ultrassom
• Manufacturer: Philips Medical Systems
• Model: EPIQ 7G System

Abstract

EMU 2014/50489-9: elastography ultrasound for safe study of dimensions and elasticity of organs in children Ultrasound Elastography uses ultrasound waves to obtaining imaging and to study elasticity of tissues, with the advantage of not using ionizing radiation, therefore harmless. The main objective of the equipment that will be installed at the Imaging Department of the Diagnostic Center "Child Friendly" of the ICr is the study of thymus dimensions and its elasticity in healthy children population of various ages and children that knownly have affected thymus, as in Down syndrome, and children submitted to situations that can damage the thymus, such as use of immunosuppressive drugs. Parallel to imaging study, a functional assessment of the organ will be accomplished through: i) determining the total number of lymphocytes and number of T helper lymphocytes (CD4 +) and cytotoxic; ii) determining the numbers of TRECs (T-cell receptor excision circles or thymic recent emigrant cells), in In turn, this multi-user equipment (EMU) should also be used by other medical researcher groups of ICr, especially those working with liver disease, where elastography ultrasound has already been proved to be very useful in identifying liver cirrhosis. (CD8 +) and order to trying to establish relationships between imaging and functional parameters. (AU)