MINA study - Maternal and child health in Acre: birth cohort in the Western Brazilian Amazon

• Grant number: 16/00270-6
• Support Opportunities: Research Projects - Thematic Grants
• Duration: April 01, 2017 - October 31, 2023
• Field of knowledge: Health Sciences - Collective Health - Epidemiology
• Principal Investigator: Marly Augusto Cardoso
• Grantee: Marly Augusto Cardoso
• Host Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Pesquisadores principais: Alicia Matijasevich Manitto ; Suely Godoy Agostinho Gimeno
• Associated researchers: Alexandre da Costa Pereira ; Bárbara Hatzlhoffer Lourenço ; Cláudio Romero Farias Marinho ; Ester Cerdeira Sabino ; Fernanda Baeza Scagliusi ; Luciana Yuki Tomita ; Marcelo Urbano Ferreira ; Marcia Caldas de Castro ; Maria Antonieta de Barros Leite Carvalhaes ; Maria Helena D'Aquino Benicio ; Rogerio Lerner ; Silvia Beatriz Boscardin
• Associated scholarship(s): 22/03400-9 - Head circumference trajectories in early childhood in Cruzeiro do Sul, Acre: associated factors and relationship with child development, BP.DD; 22/03401-5 - Remote nutritional intervention to promote healthy eating practices among Amazonian schoolchildren: a randomized clinical trial, BP.DD; 21/13371-3 - Gut microbiota and clinical expression of SARS-CoV-2 infection in children: a prospective population-based study, BP.PD; + associated scholarships 21/02096-1 - Longitudinal analysis of childhood nutritional indicators in Cruzeiro do Sul, Acre, BP.PD; 21/02467-0 - Technical training in communication strategies in birth cohort study, BP.TT; 21/01688-2 - Head circumference trajectory in early childhood in Cruzeiro do Sul, Acre, Brazil: associated factors and relationship with child development, BP.DD; 20/11603-1 - Training in communication strategies for following-up participants in cohort studies, BP.TT; 20/11792-9 - Data processing and follow-up strategies in cohort studies, BP.TT; 20/12302-5 - Technical training in the MINA-Brazil birth cohort study: collection and interpretation of maternal and child anthropometric data, BP.TT; 20/04259-2 - Maternal mental health and child development in the MINA-Brazil cohort study, BP.PD; 19/23399-2 - Food practices, emotions, feelings and affections: comparison between foods with different levels of processing, BP.IC; 19/00248-9 - Infant feeding practices and gut microbiota in a cohort study in Brazilian Western Amazon, BP.IC; 18/21057-4 - Association of vitamin D status and anthropometric outcomes in the first year of life in the MINA Brazil Study, BP.IC; 18/18557-5 - Maternal IgG antibodies and protection against clinical Vivax Malaria in the first year of life, BP.DR; 18/04040-0 - Technical training for molecular biology in cohort study, BP.TT; 18/02329-3 - Data processing and follow-up strategies in cohort studies, BP.TT; 17/22378-6 - Socioeconomic influences on the eating practices of mothers living in the Brazilian Amazon, BP.IC; 17/17424-9 - Health and Well-Being in Obesity: evaluation of an interdisciplinary intervention based on the "Health at every size" approach for obese women., BE.PQ; 17/05019-2 - Longitudinal analysis of childhood growth determinants in early childhood in Cruzeiro do Sul, state of Acre, BP.PD; 17/07836-8 - Feeding practices and head circumference of 12 months old children in Cruzeiro do Sul, state of Acre, BP.IC; 17/07894-8 - Breastfeeding practices in the first year of life of babies in Cruzeiro do Sul, state of Acre, BP.IC; 17/05651-0 - Ultra processed food consumption and feeding practices of mothers in Cruzeiro do Sul, Acre: a mixed-methods approach, BP.PD - associated scholarships

Abstract

This research line integrates a program of epidemiological surveys on maternal and child health and nutrition in the city of Cruzeiro do Sul, Acre state, Western Brazilian Amazon. This is the first birth cohort study in a malaria endemic area - Materno-Infantil no Acre (MINA Study). The central hypothesis is focused on the relations among socioeconomic, intergenerational, and child nutritional and morbidity exposures and the health profile observed during childhood. It is speculated that such associations encompass a double burden of disease, which may affect the development since early stages of life. The overall objective aims to identify early determinants to promote infant growth and development with prevention of morbidities and nutritional deficiencies, without leading to excessive weight gain and adiposity. The main lines of research are: a) Anemia, nutritional status and micronutrient deficiencies; b) Malaria and other infections; c) Maternal lifestyle (dietary patterns, physical activity, smoking, alcohol and illegal drugs); d) Weight gain, genetic factors and maternal and child metabolic disorders; e) Maternal mental health and child development; and f) Intestinal microbiota and child feeding behavior. The study design will be a population-based birth cohort. Obstetric, prenatal care and morbidity data, socioeconomic characteristics, dietary intake and biochemical indicators of mothers and their babies will be collected during the follow-up period. Findings of the present study will contribute to the current knowledge on mechanisms and impact of biological and psychosocial factors of determinants of maternal and child health, supporting the planning of interventions aimed at reducing the risk associated with morbidity and nutritional disorders and their consequences on maternal and child health. (AU)

Scientific publications

(17)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LOURENCO, BARBARA HATZLHOFFER; LIMA, DANIEL LEAL; VIVANCO, EDWIN; FERNANDES, RACHELLE DE BRITO; DUARTE, MIRIAN; RIBEIRO NEVES, PAULO AUGUSTO; DE CASTRO, MARCIA CALDAS; CARDOSO, MARLY AUGUSTO; GRP, MINA-BRAZIL STUDY. Agreement between antenatal gestational age by ultrasound and clinical records at birth: A prospective cohort in the Brazilian Amazon. PLoS One, v. 15, n. 7, JUL 14 2020. (16/00270-6)

DAL BOM, JULIANA PAGHI; MAZZUCCHETTI, LALUCHA; MALTA, MAIRA BARRETO; LADEIA-ANDRADE, SIMONE; DE CASTRO, MARCIA CALDAS; CARDOSO, MARLY AUGUSTO; LOURENCO, BARBARA HATZLHOFFER; MANITTO, ALICIA MATIJASEVICH; ABANTO, JENNY; AGOSTINHO GIMENO, SUELY GODOY; et al. Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region. PLoS One, v. 14, n. 8, AUG 6 2019. (16/00270-6)

PINCELLI, ANACLARA; NEVES, PAULO A. R.; LOURENCO, BARBARA H.; CORDER, RODRIGO M.; MALTA, MAIRA B.; SAMPAIO-SILVA, JULIANA; DE SOUZA, RODRIGO M.; CARDOSO, MARLY A.; CASTRO, MARCIA C.; FERREIRA, MARCELO U.; et al. The Hidden Burden of Plasmodium vivax Malaria in Pregnancy in the Amazon: An Observational Study in Northwestern Brazil. American Journal of Tropical Medicine and Hygiene, v. 99, n. 1, p. 73-83, 2018. (16/00270-6)

CARDOSO, MARLY A.; MATIJASEVICH, ALICIA; MALTA, MAIRA BARRETO; LOURENCO, BARBARA HATZLHOFFER; GIMENO, SUELY G. A.; FERREIRA, MARCELO U.; CASTRO, MARCIA C.; GRP, MINA-BRAZIL STUDY. Cohort profile: the Maternal and Child Health and Nutrition in Acre, Brazil, birth cohort study (MINA-Brazil). BMJ OPEN, v. 10, n. 2, FEB 2020. (16/00270-6, 17/05019-2)

SATO, PRISCILA DE MORAIS; COUTO, MARCIA THEREZA; WELLS, JONATHAN; CARDOSO, MARLY AUGUSTO; DEVAKUMAR, DELANJATHAN; SCAGLIUSI, FERNANDA BAEZA. Mothers' food choices and consumption of ultra -processed foods in the Brazilian Amazon: A grounded theory study. APPETITE, v. 148, MAY 1 2020. (18/19279-9, 16/00270-6, 17/05651-0)

NEVES, PAULO A. R.; CAMPOS, CHIARA A. S.; MALTA, MAIRA B.; LOURENCO, BARBARA H.; CASTRO, MARCIA C.; CARDOSO, MARLY A.; MANITTO, ALICIA MATIJASEVICH; LOURENCO, BARBARA HATZLHOFFER; MALTA, MAIRA BARRETO; CARDOSO, MARLY AUGUSTO; et al. Predictors of vitamin A status among pregnant women in western Brazilian Amazon. BRITISH JOURNAL OF NUTRITION, v. 121, n. 2, p. 202-211, JAN 28 2019. (16/00270-6)

SATO, PRISCILA DE MORAIS; ULIAN, MARIANA DIMITROV; DA SILVA OLIVEIRA, MAYARA SANAY; CARDOSO, MANLY AUGUSTO; WELLS, JONATHAN; DEVAKUMAR, DELANJATHAN; LOURENCO, BARBARA HATZLHOFFER; SCAGLIUSI, FERNANDA BAEZA. Signs and strategies to deal with food insecurity and consumption of ultra-processed foods among Amazonian mothers. GLOBAL PUBLIC HEALTH, v. 15, n. 8, APR 2020. (16/00270-6, 18/19279-9, 17/05651-0)

SATO, PRISCILA DE MORAIS; LOURENCO, BARBARA HATZLHOFFER; MACHADO, RAFAELA DO MANCO; CARDOSO, MARLY AUGUSTO; SCAGLIUSI, FERNANDA BAEZA. Food Classifications by Brazilian Amazon Mothers: Interactions With Eating Practices. JOURNAL OF NUTRITION EDUCATION AND BEHAVIOR, v. 53, n. 10, p. 880-885, OCT 2021. (18/19279-9, 17/05651-0, 16/00270-6, 19/23399-2)

PINCELLI, ANACLARA; CARDOSO, MARLY A.; MALTA, MAIRA B.; JOHANSEN, IGOR C.; CORDER, RODRIGO M.; NICOLETE, VANESSA C.; SOARES, IRENE S.; CASTRO, MARCIA C.; FERREIRA, MARCELO U.; GRP, MINA-BRAZIL STUDY WORKING. Low-level Plasmodium vivax exposure, maternal antibodies, and anemia in early childhood: Population-based birth cohort study in Amazonian Brazil. PLoS Neglected Tropical Diseases, v. 15, n. 7, JUL 2021. (16/00270-6, 17/05019-2, 18/18557-5, 20/07020-0)

BRUNO PEREIRA DA SILVA; ALICIA MATIJASEVICH; MAÍRA BARRETO MALTA; PAULO A R NEVES; MARIA CRISTINA MAZZAIA; MARIA CRISTINA GABRIELLONI; MÁRCIA C CASTRO; MARLY AUGUSTO CARDOSO. Transtorno mental comum na gravidez e sintomas depressivos pós-natal no estudo MINA-Brasil: ocorrência e fatores associados. Revista de Saúde Pública, v. 56, 2022-09-26. (16/00270-6)

PAOLA SOLEDAD MOSQUERA; BÁRBARA HATZLHOFFER LOURENÇO; MARLY AUGUSTO CARDOSO. Frequência do aleitamento materno exclusivo aos 30 dias de vida: revisão de estudos longitudinais. Saúde e Sociedade, v. 31, n. 4, 2022-12-05. (16/00270-6)

DA SILVA OLIVEIRA, MAYARA SANAY; SATO, PRISCILA DE MORAIS; ARCENO, MARK ANTHONY; ULIAN, MARIANA DIMITROV; UNSAIN, RAMIRO FERNANDEZ; CARDOSO, MARLY AUGUSTO; SCAGLIUSI, FERNANDA BAEZA. ``It's women's obligation:{''} constitutive elements of gendered domestic cooking practices performed by women from western Brazilian Amazon. FOOD CULTURE & SOCIETY, JUN 2021. (16/00270-6)

KELLY APARECIDA KANUNFRE; MUSSYA CISOTTO ROCHA; MAÍRA BARRETO MALTA; RODRIGO MEDEIROS DE SOUZA; MARCIA CALDAS CASTRO; SILVIA BEATRIZ BOSCARDIN; HIGO FERNANDO SANTOS SOUZA; STEVEN S. WITKIN; MARLY AUGUSTO CARDOSO; THELMA SUELY OKAY. Silent circulation of Chikungunya virus among pregnant women and newborns in the Western Brazilian Amazon before the first outbreak of chikungunya fever. Revista do Instituto de Medicina Tropical de São Paulo, v. 64, 2022-04-04. (16/00270-6)

ANA ALICE DE ARAÚJO DAMASCENO; PAOLA SOLEDAD MOSQUERA; MAÍRA BARRETO MALTA; ALICIA MATIJASEVICH; MARLY AUGUSTO CARDOSO. Concordância entre informações registradas no cartão pré-natal e no estudo MINA-Brasil. Ciênc. saúde coletiva, v. 27, n. 4, p. 1619-1628, 2022-04-22. (17/05019-2, 16/00270-6)

RAMOS DE OLIVEIRA, CLARIANA V.; NEVES, PAULO A. R.; LOURENCO, BARBARA H.; MEDEIROS DE SOUZA, RODRIGO; MALTA, MAIRA B.; FUJIMORI, ELIZABETH; CARDOSO, MARLY A.; CASTRO, MARCIA C.; GRP, MINA BRAZIL STUDY. renatal care and preterm birth in the Western Brazilian Amazon: A population-based stud. GLOBAL PUBLIC HEALTH, v. 17, n. 3, JAN 2021. (16/00270-6)

MOSQUERA, PAOLA SOLEDAD; LOURENCO, BARBARA H.; GIMENO, SUELY G. A.; MALTA, MAIRA B.; CASTRO, MARCIA C.; CARDOSO, MARLY AUGUSTO; MANITTO, ALICIA MATIJASEVICH; DAMASCENO, ANA ALICE; DA SILVA, BRUNO PEREIRA; DE SOUZA, RODRIGO MEDEIROS; et al. Factors affecting exclusive breastfeeding in the first month of life among Amazonian children. PLoS One, v. 14, n. 7, JUL 11 2019. (16/00270-6)

NEVES, PAULO A. R.; LOURENCO, BARBARA H.; PINCELLI, ANACLARA; MALTA, MAIRA B.; SOUZA, RODRIGO M.; FERREIRA, MARCELO U.; CASTRO, MARCIA C.; CARDOSO, MARLY A.; DA SILVA, BRUNO PEREIRA; DE SOUZA, RODRIGO MEDEIROS; et al. High prevalence of gestational night blindness and maternal anemia in a population-based survey of Brazilian Amazonian postpartum women. PLoS One, v. 14, n. 7, JUL 3 2019. (16/00270-6)